Designs For Health Magnesium Threonate
Directions: Designs For Health Magnesium Threonate
Each scoop provides 1g of pure magnesium threonate powder
Doses used in research range from 1.5g - 2g daily (1.5 - 2 scoops)
Please use as directed by your health practitioner.
For extemporaneous compounding only.
Benefits: Designs For Health Magnesium Threonate
- Each scoop provides 1g of pure Magnesium threonate
- Utilises Magtein, a clinically researched form of Magnesium Threonate
- Vegan Friendly
- 100 % Pure
- Unflavoured and Excipient Free
Ingredients: Designs For Health Magnesium Threonate
|Each 1g scoop contains:
Excipients: Designs For Health Magnesium Threonate
Allergen Information: Designs For Health Magnesium Threonate
- No Added: Gluten, Eggs, Soy, Sesame, Nuts, Dairy.
- Free From: Sulfites, Flavours and Colours (100% Pure)
- Vegan Friendly
Quality Guarantee: Designs For Health Magnesium Threonate
Designs for Health medicines that are listed on the Australian Register of Therapeutic Goods will display an AUSTL number on the label.
Listed medicines in Australia need to be manufactured according to legislated standards set out in Therapeutic Goods Order 101.
TGO101 legislation sets out minimum quality standards for medicines supplied in Australia that display an AUSTL number.
TGO101 mandates testing for:
- Impurities such as heavy metals (including lead, mercury, cadmium and arsenic), pesticides and residual solvents
- Dissolution (to ensure the capsule will dissolve once taken)
- Uniformity (to ensure that every capsule is the same)
- Final assay testing is also performed to ensure that what we have on the label is in each capsule, and microbiological testing is performed to ensure that no microbial contamination has occurred during the encapsulation and packing process.
Warnings: Designs For Health Magnesium Threonate
If symptoms persist, talk to your health professional.
Dietary supplements should not replace a balanced diet.
- Caution advised with use of magnesium in individuals with renal dysfunction.1
- Excessive intake of magnesium may cause diarrhoea and gastric irritation.1,5
- Excessive intake of magnesium may result in reduced calcium levels.1
- Magnesium may potentiate the therapeutic effect of calcium-channel blockers and neuroblocker medications.1
- Long term use of loop and thiazide diuretics increase urinary magnesium excretion.1,5
- Magnesium may decrease absorption of fluoroquinolones. Separate doses by at least 2 hours before and 4 hours after oral magnesium.1
Education: Designs For Health Magnesium Threonate
The human body contains around 24g of Magnesium, and it is present in the serum, muscles and soft tissues, bones and extracellular fluid. It is also found in the cerebrospinal fluid where it regulates various brain functions, mainly related to excitatory neuronal function.11
Magnesium is a critical regulator of the activity rate of the Sodium-Potassium ATPase pump (Na+, K+- ATPase pump)2 which is required for the removal of sodium from inside the cell in exchange for potassium (i.e., brings potassium back into the cell despite the chemical gradient favouring potassium movement out of the cell).3 This makes Magnesium critical for maintaining the electrical potential of skeletal and cardiac muscles and nerves and for neurotransmission across neuromuscular and neuronal junctions.2,3
Further to regulating the activity of the pumps and therefore the electrical potential, Magnesium in the extracellular space facilitates optimal neurotransmitter binding at the neuronal receptor site.7
Magnesium is a calcium antagonist and competes with calcium for binding sites on calcium channels.8 Magnesium can displace calcium at N-methyl-D-aspartate (NMDA) glutamate binding/ receptor sites preventing their activation.
NMDA receptor activation is associated with numerous biological outcomes such as synaptic plasticity, learning and memory, pain emergence and migraine, sleep6,9 and mood fluctuations.10
NMDA receptors are ion-channels that arbitrate the movement of calcium across synapses. An increase in calcium influx causes glutamate release and consequent excitatory neurotransmission in the central nervous system.6,9,11
Excessive calcium influx in the brain may also disrupt the blood brain barrier, inflammation and oxidative stress.11
Magnesium can also agonise GABAA receptors inhibiting neuronal excitation.11
Magtein has been trialled in both preclinical and clinical studies.12,13