Cell-Logic EnduraCell Plus

Description

Cell-Logic EnduraCell Plus formulation is based on the same grade and quantity of EnduraCell but with the addition of 25 mcg selenium per capsule. Many of the enzymes which increase cellular defences, depend upon seleno-enzymes.

Features

Cell-Logic EnduraCell Plus may:

• Stimulate cellular antioxidant defences within the body
• Activate key enzymes in liver detoxification
• Support selenium deficient diets
• Aid thyroid metabolism and protection
• Support gut homeostasis and immune function

Cell-Logic EnduraCell Plus combines 100% Whole Broccoli Sprout powder with a natural source of selen-ium. Selenium is a trace element that is associated with the production of cell-protective compounds activated by broccoli phytonutrients.

Endura Cell Plus does not contain goitrogens or significant levels of Vitamin K.

Active Ingredients

Free From

Cell-Logic EnduraCell is hydroganically grown in a carefully controlled environment to maximise bioactivity. Cell-Logic's hydrogranic growing process does not use herbicides, pesticides or other harmful chemicals.

Cell-Logic EnduraCell Plus is GMO free

Dosage

Adults:

Take 1-3 capsules twice daily or as directed by your healthcare practitioner.

Warnings

This product contains selenium which is toxic in high doses.

For adults, a daily dose of 150 mi-crograms of selenium from dietary supplements should not be exceeded.

Do not exceed 6 capsules daily.

Very occasionally, gastro-intestinal adverse effects have been reported, and include nausea, gastro-abdominal discomfort and diarrhoea. Limited data available seem to indicate that such effects are limited to certain pre-existing gastro-intestinal conditions, in particular, those with dysbiosis. However, it has been observed that for those affected, the dose can be managed in a manner whereby the symptoms disappear and may not recur even after the consumption of larger doses. Click here for further information on this and on how to address the effects. 

Storage

Store below 30° away from light and moisture.

Evidence

1. Li D et al. Synergy between broccoli sprout extract and selenium in the upregulation of thioredoxin reductase in human hepatocytes Food Chemistry 110 (2008) 193–198
2. Lee J-M, Johnson JA. An Important Role of Nrf2-ARE Pathway in the Cellular Defense Mechanism Journal of Biochemistry and Molecular Biology 2004 ; 37(2):139-143
3. Fahey JW, Talalay P.  Antioxidant Functions of Sulforaphane: a Potent Inducer of Phase II Detoxication Enzymes. Food and Chemical Toxicology. 1999; 37:973-979
4. Fahey JW, Kensler TW. Role of dietary supplements/nutraceuticals in chemoprevention through induction of cytoprotective enzymes. Chem Res Toxicol. 2007 Apr;20(4):572-6.
5. Yeh C-T, Yen G-C.  Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells. Carcinogenesis 2005;26 (12) ;2138–2148
6. Jeong W-S et al. Modulatory Properties of Various Natural Chemopreventive Agents on the Activation of NF-κB Signaling Pathway. Pharmaceutical Research. 2004;21(4): 661-670.
7. Innmorato NG et al. The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation. The Journal of Immunology 2008;181:680 – 689.
8. Wu L, Juurlink B The impaired glutathione system and its up-regulation by sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats. Journal of Hypertension 2001, 19:181-1825
9. Cramer J, Jeffery EH. Sulforaphane Absorption and Excretion Following Ingestion of a Semi-Purified Broccoli Powder Rich in Glucoraphanin and Broccoli Sprouts in Healthy Men.2011;  Nutrition and Cancer, 63(2), 196–201
10. Halliwell B Free radicals and antioxidants – quo vadis? Trends in Pharmacological Sciences 2011: 32(3):125-130.
11. Kensler TW et al.  Translational Strategies for cancer prevention in liver. Nature Reviews Cancer 3, 321-329 (May 2003)
12. 2001 Steinkellner H et al. Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.  Mutation Research 480–481 (2001) 285–297.