Designs For Health Liposomal Vitamin D3 50ml
Directions: Designs For Health Liposomal Vitamin D3
Take 1 spray (285 microlitres) once daily by mouth, or as directed by your healthcare professional.
Spray into the mouth under the tongue and hold in the mouth for 30 seconds before swallowing. Take on an empty stomach.
Always read the label. Follow the directions for use. This medicine may not be right for you. Read the warnings before purchase.
Always read the label. Follow the directions for use. If symptoms persist, worsen, or change unexpectedly, talk to your health professional. This medicine may not be right for you. Read the warnings before purchase.
Description: Designs For Health Liposomal Vitamin D3
Vitamin D is a fat-soluble secosteroid hormone that can be found in three main forms – vitamin D (calcitriol), vitamin D2 (ergocalciferol), and vitamin D3 (colecalciferol). Calcitriol is endogenously produced in the body via ultraviolet B exposure to the epidermis.1 Ergocalciferol is the synthetic form of vitamin D and is most commonly added to food. Colecalciferol is synthesised in the skin from 7-dehydrocholesterol and is also found in a limited range of food sources such as shiitake mushrooms and oily fish. Vitamin D is required for a vast number of biological processes.
Due to a number of disease states having low vitamin D status in common, serum vitamin D as 25-hydroxyvitamin D (25(OH) D) is often routinely tested. Vitamin D supplementation is suggested in those with a clinical vitamin D deficiency. Variations in vitamin D status are heavily dependent upon a number of factors, including sex, season, location, age, health conditions, and lifestyle.
Liposomes are vesicles with phospholipid bilayers surrounding an aqueous or lipid solution. The phospholipid make-up of the bilayer allows for the liposomes to permeate the cell membrane and promote cell to cell fusion, resulting in delivery of the nutrients enclosed within the liposomes into the cells.
Liposomal technology enhances bioavailability and absorption.3 Efficient intracellular delivery is achieved via superior absorption of the smaller sized liposome particles. Liposomal delivery also allows for greater stability in the bloodstream and can be retained in the blood without degradation or oxidation.
Vitamin D plays a primary role in maintaining bone health and integrity. Both bone mass and mineralisation require adequate vitamin D levels. Two of the main nutrients involved in strengthening the bone matrix, calcium and phosphorous, require adequate vitamin D in order to maintain homeostasis. Evidence suggests that as we age, vitamin D levels can decrease, leading to an imbalance in calcium and phosphorous.6 Hormonal factors also influence bone resorption and formation – therefore, vitamin D is both, directly and indirectly, responsible for processes involved in the mineralisation of the extracellular matrix in bone tissue.
The immune system requires optimal vitamin D levels to function. A number of important immune cells have vitamin D receptors and vitamin D metabolising enzymes, including monocytes, B cells, T cells, and antigen-presenting cells.
Results from in vivo human and animal studies show numerous beneficial outcomes for immune function with vitamin D supplementation.8 Calcitriol has specifically been shown to enhance macrophage and monocyte antimicrobial activity, as well as enhance innate immune cell chemotaxis and phagocytosis.8 Calcitriol is also involved in adaptive immunity where it directly influences B cell homeostasis, memory and plasma cell inhibition, and promotion of apoptosis of immunoglobulins responsible for producing B cells.
Maternal health and foetal development
Vitamin D has a vital role in foetal development due to its requirement in maintaining calcium homeostasis and supporting healthy bone growth. Young children and pregnant women are at particular risk of vitamin D deficiency, with numerous studies linking low serum 25(OH)D to poor health outcomes that can extend beyond bone health.9 Maternal 25(OH)D is believed to cross the human placenta to the foetus, as has been demonstrated in rat studies. The placenta possesses vitamin D receptors, as well as producing the enzyme CYP27B1 which is responsible for the conversion of 25(OH)D to the active form of vitamin D.
There is also a demonstrated connection between vitamin D, immune function, and maternal health. Adequate vitamin D levels support immune function, which may provide support for the appropriate maternal immune response to the placenta.
Ingredients: Designs For Health Liposomal Vitamin D3
<Content for ingredients from Info sheet Ingredients>
|Active Ingredients per 285 microlitre (1 spray) serve|
|Liposomal Vitamin D3 (as Colecalciferol) Colecalciferol||25micrograms|
|equiv. Vitamin D3||1000IU|
Excipients: Designs For Health Liposomal Vitamin D3
equiv phospholipids 40.7 mg/g
Orange oil (flavour)
Allergen Information: Designs For Health Liposomal Vitamin D3
No added: Soy, Gluten, Dairy, Eggs. Yeast, Sesame, Nuts.
Free From: Sulfites, Benzoates, Artificial Colours, Artificial Flavours.
Storage: Designs For Health Liposomal Vitamin D3
Store at 2-8 degrees, Refrigerate, do not freeze.
Warnings: Designs For Health Liposomal Vitamin D3
Contains 12% Ethanol