{"id":8252651340006,"title":"RN Labs Selenium","handle":"rn-labs-selenium","description":"\u003ch2\u003eRN Labs Selenium\u003cbr\u003e\n\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eHelp Prevent Dietary Selenium Deficiency and Maintenance of Healthy Thyroid Hormones, Antioxidant Support and Support Detoxification\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eSize: 60 Capsules\u003c\/p\u003e\n\u003cp\u003eRN Labs Selenium AUST L 389882\u003c\/p\u003e\n\u003cp\u003eRN Labs Selenium is part of the RN Labs Range of Practitioner Brand quality naturopathic medicines available for patients under the care of a practitioner.\u003c\/p\u003e\n\u003cp\u003eRN Labs was formerly named Research Nutrition.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #ff2a00;\"\u003eTo access RN Labs Selenium select the \u003ca href=\"#how-to-access\" title=\"How To Access RN Labs Naturopathic Medicines 10% off RRP | HealthMasters RN Labs\"\u003e\u003cspan style=\"text-decoration: underline;\"\u003eHow To Access tab\u003c\/span\u003e\u003c\/a\u003e for more information.\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eSummary\u003c\/h5\u003e\n\u003ch2\u003eSummary: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eRN Labs Selenium capsules help to prevent dietary selenium deficiency, for the maintenance of healthy thyroid hormones, antioxidant support and the support of detoxification processes.\u003c\/p\u003e\n\u003ch5\u003eIndications\u003c\/h5\u003e\n\u003ch2\u003eIndications: RN Labs Selenium\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSelenomethionine is an easily absorbed and utilised form of Selenium\u003c\/li\u003e\n\u003cli\u003eSupports healthy thyroid hormone metabolism\u003c\/li\u003e\n\u003cli\u003eassists activation of Thyroxine (T4) to Triiodothyronine (T3)\u003c\/li\u003e\n\u003cli\u003eSupports production of Glutathione for natural liver detoxification processes\u003c\/li\u003e\n\u003cli\u003eSupports antioxidant functions in the body\u003c\/li\u003e\n\u003cli\u003eas a cofactor for glutathione peroxidase activity\u003c\/li\u003e\n\u003cli\u003eSupports immune system defences\u003c\/li\u003e\n\u003cli\u003eassists inhibition of viral and bacterial infections\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eDosage\u003c\/h5\u003e\n\u003ch2\u003eDosage: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eAdults take 1 capsule per day, or as instructed by a healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eActive Ingredients\u003c\/h5\u003e\n\u003ch2\u003eActive Ingredients: \u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach Vegetarian Capsule Contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSelenomethionine\u003c\/td\u003e\n\u003ctd\u003e373micrograms\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEquiv. to elemental Selenium\u003c\/td\u003e\n\u003ctd\u003e150micrograms\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eExcipients: Leucine, Hypromellose (Capsule), Microcrystalline\u003c\/p\u003e\n\u003cp\u003eCellulose, Colloidal Anhydrous Silica.\u003c\/p\u003e\n\u003cp\u003eSuitable for vegans.\u003c\/p\u003e\n\u003ch5\u003eAllergen Information\u003c\/h5\u003e\n\u003ch2\u003eAllergen Information: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eRN Labs Selenium does NOT contain any wheat, gluten, dairy, lactose, egg, yeast, soy, artificial colours, artificial sweeteners, or artificial flavours.\u003c\/p\u003e\n\u003cp\u003eRN Labs Selenium also does not contain artificial preservatives, stearate lubricants and other commonly detrimental excipients\u003c\/p\u003e\n\u003ch5\u003eResearch Highlights\u003c\/h5\u003e\n\u003ch2\u003eResearch Highlights: RN Labs Selenium\u003c\/h2\u003e\n\u003ch3\u003eSelenomethionine Absorption\u003c\/h3\u003e\n\u003cp\u003eOne study measured the effects of different forms of Selenium on plasma biomarkers (including selenium concentration, selenoprotein P concentration, and glutathione peroxidase activity) as well as urinary selenium excretion. Supplementation with Selenomethionine, and high- Selenium yeast raised the plasma selenium concentration in a dose-dependant manner, whilst Selenite did not. The higher urinary selenium excretion or Selenomethionine, determined that this form is better absorbed than Selenite.\u003c\/p\u003e\n\u003cp\u003eA review found that organic Selenium forms (such as Selenomethionine) increased blood selenium concentration more rapidly and to a greater extent than inorganic forms (such as selenite or selenate).\u003c\/p\u003e\n\u003ch3\u003eAntioxidant Support\u003c\/h3\u003e\n\u003cp\u003eSelenium supplementation has demonstrated an effective increase in serum Selenium, and subsequently increasing the antioxidant enzyme Glutathione Peroxidase (GSH-Px) activity, for which Selenium is an essential component.\u003c\/p\u003e\n\u003cp\u003eSome long term studies have demonstrated that Selenium supplementation over a 24 week intervention period, was able to reduce the oxidation marker Malondyaldehyde (MDA), as well as increasing serum Glutathione. One study in particular, by Razavi and colleagues, found that in PCOS patients, Selenium supplementation for 8 weeks was effective in reducing MDA, inflammatory markers and also improved reproductive outcomes.\u003c\/p\u003e\n\u003ch3\u003eThyroid Hormone Metabolism\u003c\/h3\u003e\n\u003cp\u003eSelenium, as Selenoproteins, contribute to thyroid hormone biosynthesis and metabolism, antioxidant defence and control of redox processes in thyrocytes. Selenium has, in particular, a significant role in converting inactive thyroid hormone T4 to T3 to be utilised by the body.\u003c\/p\u003e\n\u003cp\u003eOne double-blind placebo-controlled trial by Olivieri et al, found a significant improvement of selenium indices, and a decrease in T4 following selenium supplementation. Compared with the placebo treated group, which found that serum selenium, erythrocyte glutathione peroxidase activity and thyroid hormones were unchanged. The authors concluded that selenium status influences thyroid hormones.\u003c\/p\u003e\n\u003cp\u003eA study by Kobayashi and colleagues, found that selenium supplementation in patients with abnormal thyroid levels, resulted in a significantly decreased TSH, FT4, and FT4\/FT3 ratio, and increased FT3.\u003c\/p\u003e\n\u003ch3\u003eSelenium as a Co-Factor\u003c\/h3\u003e\n\u003cp\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" alt=\"RN Labs Selenium- Selenium as a Co-Factor at HealthMasters RN Labs\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/RNLabsSelenium-SeleniumasaCo-FactoratHealthMastersRNLabs_1024x1024.png?v=1690446492\"\u003e\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eFOR PRACTITIONER DISPENSING ONLY.\u003c\/p\u003e\n\u003cp\u003eSafety has not been confirmed during pregnancy \u0026amp; lactation.\u003c\/p\u003e\n\u003cp\u003eSelenium is toxic in high doses, it is recommended that a daily dose of 150 micrograms for adults of selenium from dietary supplements not be exceeded.\u003c\/p\u003e\n\u003ch5\u003eQuality and Purity\u003c\/h5\u003e\n\u003ch2\u003eQuality and Purity: RN Labs Selenium\u003c\/h2\u003e\n\u003ch3\u003eRN Labs use only the highest grade ingredients and materials available. RN Labs' purity standards for manufacturing and sourcing are extensively researched and verified.\u003c\/h3\u003e\n\u003cp\u003eRN Labs Selenium is a pure and hypoallergenic product, developed to meet the needs of even the most sensitive patients.\u003c\/p\u003e\n\u003ch3\u003ePure and Free From\u003c\/h3\u003e\n\u003cp\u003eRN Labs Selenium is formulated with no harsh or irritating excipients, ensuring comfort, safety and efficacy for improved patient compliance and results.\u003c\/p\u003e\n\u003ch5\u003eThe RN Difference\u003c\/h5\u003e\n\u003ch2\u003eThe RN Labs Difference: \u003c\/h2\u003e\n\u003cstyle\u003e\u003c!--\n.embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; }\n--\u003e\u003c\/style\u003e\n\u003cdiv class=\"embed-container\"\u003e\u003ciframe src=\"https:\/\/player.vimeo.com\/video\/325810732\" allowfullscreen=\"\" mozallowfullscreen=\"\" webkitallowfullscreen=\"\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: \u003c\/h2\u003e\n\u003cp\u003eAdeoye et al, 2018, Review on the role of glutathione on oxidative stress and infertility, JBRA assisted reproduction.\u003c\/p\u003e\n\u003cp\u003eAgostoni C et al, 2014, Scientific Opinion on Dietary Reference Values for selenium, European Food Safety Authority Journal.\u003c\/p\u003e\n\u003cp\u003eBurk, RF et al, 2006, Effects of Chemical Form of Selenium on Plasma Biomarkers in a High-Dose Human Supplementation Trial, Cancer Epidemiology, Biomarkers \u0026amp; Prevention.\u003c\/p\u003e\n\u003cp\u003eDorea JG, 2002, Selenium and breast-feeding, The British Journal of Nutrition.\u003c\/p\u003e\n\u003cp\u003eKang et al, 1997, Effect of diet induced hypercholesterolemia and selenium supplementation in nitric oxide synthase activity. Archives of physiology and biochemistry.\u003c\/p\u003e\n\u003cp\u003eKawai et al, 2018, Thyroid hormone status in patients with severe selenium deficiency, Clinical Pediatric Endocrinology.\u003c\/p\u003e\n\u003cp\u003eKe et al, 2020, Reduced glutathione ameliorates liver function, oxidative stress and inflammation after interventional therapy for hepatocellular carcinoma. Journal of B.U.ON.\u003c\/p\u003e\n\u003cp\u003eKoboyashi et al, 2021, Thyroid function in patients with selenium deficiency exhibits high free T4 to T3 ratio, Clinical Pediatric Endocrinology.\u003c\/p\u003e\n\u003cp\u003eKöhrle et al, 2009, Selenium and Thyroid, Best practice \u0026amp; research.\u003c\/p\u003e\n\u003cp\u003eLook et al, 1997, Serum selenium, plasma glutathione (GSH) and erythrocyte glutathione peroxidase (GSH-Px) levels in asymptomatic versus symptomatic human immunodeficiency virus-1 (HIV-1)-infection. European Journal of Clinical Nutrition.\u003c\/p\u003e\n\u003cp\u003eMahmoodianfard et al, Effects of Zinc and Selenium Supplementation on Thyroid Function in Overweight and Obese Hypothyroid Female Patients: A Randomized Double-Blind Controlled Trial. Journal of the American College of Nutrition.\u003c\/p\u003e\n\u003cp\u003eMuri et al, 2020, Redox regulation of immunometabolism, Nature reviews. Immunology. Nève J, 1995, Human Selenium Supplementation as Assessed by Changes in Blood Selenium Concentration and Glutathione Peroxidase Activity, Journal of Trace Elements in Medicine and Biology.\u003c\/p\u003e\n\u003cp\u003eOlivieri O et al, 1995, Low Selenium Status in the Elderly Influences Thyroid Hormones, Clinical Science (London).\u003c\/p\u003e\n\u003cp\u003eOzturk et al, 2008, Comparison of plasma malondialdehyde glutathione, glutathione peroxidase, hydroxyproline and selenium levels in patients with vitiligo and healthy controls. Indian Journal of Dermatology.\u003c\/p\u003e\n\u003cp\u003eRazavi et al, 2016, Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome. Hormone and metabolic research.\u003c\/p\u003e\n\u003cp\u003eRohr-Udilova, 2012, Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. Hepatology.\u003c\/p\u003e\n\u003cp\u003eSalama, 2007, The role of selenium in critical illness: Basic science and clinical implications. Indian Journal of Critical Care Medicine\u003c\/p\u003e\n\u003cp\u003eSavory et al, 2012, Selenium supplementation and exercise: effect on oxidant stress in overweight adults. Obesity (Silver Spring).\u003c\/p\u003e\n\u003cp\u003eSteinbrenner et al, 2013, Toward Understanding Success and Failures in the Use of Selenium for Cancer Prevention. Antioxidants \u0026amp; Redox Signalling.\u003c\/p\u003e\n\u003cp\u003eShidfar, 2018, Regression of Non alcoholic Fatty Liver Disease with Zinc and Selenium Co-Supplementation after Disease Progression in Rats. Iranian journal of medical sciences.\u003c\/p\u003e\n\u003cp\u003eThomson et al, 1993, Long-term supplementation with selenate and selenomethionine: Selenium and glutathione peroxidase (EC 1.11.1.8) in blood components of New Zealand women. British Journal of Nutrition.\u003c\/p\u003e\n\u003cp\u003eXu et al, 2022, The Role and Mechanisms of Selenium Supplementation on Fatty Liver-Associated Disorder, Antioxidants.\u003c\/p\u003e\n\u003cp\u003eYun et al, 2007, NF-kappaB signaling pathway, not IFN-beta\/STAT1, is responsible for the selenium suppression of LPS-induced nitric oxide production. International immunopharmacology.\u003c\/p\u003e\n\u003cp\u003eZakeri et al, 2021, Selenium supplementation and oxidative stress: A review. PharmaNutrition\u003c\/p\u003e\n\u003cp\u003eSteinbrenner et. al. 2015. Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections. Adv Nutr. 6(1): 73–82\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2023-07-27T18:17:55+10:00","created_at":"2023-07-27T17:58:34+10:00","vendor":"RN Labs","type":"RN Labs Naturopathic Medicines","tags":["Naturopathic","PB","RN Labs"],"price":1917,"price_min":1917,"price_max":1917,"available":true,"price_varies":false,"compare_at_price":2130,"compare_at_price_min":2130,"compare_at_price_max":2130,"compare_at_price_varies":false,"variants":[{"id":43845463015654,"title":"60 Capsules","option1":"60 Capsules","option2":null,"option3":null,"sku":"RNLSelenium60C","requires_shipping":true,"taxable":true,"featured_image":{"id":39712600686822,"product_id":8252651340006,"position":2,"created_at":"2023-07-27T18:14:16+10:00","updated_at":"2023-07-27T18:14:19+10:00","alt":"RN Labs Selenium 60 Capsules 10% off RRP at HealthMasters RN Labs","width":1200,"height":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/RNLabsSelenium60Capsules10_offRRPatHealthMastersRNLabs.png?v=1690445659","variant_ids":[43845463015654]},"available":true,"name":"RN Labs Selenium - 60 Capsules","public_title":"60 Capsules","options":["60 Capsules"],"price":1917,"weight":0,"compare_at_price":2130,"inventory_quantity":29994,"inventory_management":"shopify","inventory_policy":"deny","barcode":null,"featured_media":{"alt":"RN Labs Selenium 60 Capsules 10% off RRP at HealthMasters RN 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Labs Selenium 10% off RRP at HealthMasters RN Labs Logo","id":32315635761382,"position":3,"preview_image":{"aspect_ratio":3.0,"height":100,"width":300,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/RNLabsLogo_f74f9ccd-a4d2-40c3-b63c-97562188be6e.jpg?v=1690445659"},"aspect_ratio":3.0,"height":100,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/RNLabsLogo_f74f9ccd-a4d2-40c3-b63c-97562188be6e.jpg?v=1690445659","width":300}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch2\u003eRN Labs Selenium\u003cbr\u003e\n\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eHelp Prevent Dietary Selenium Deficiency and Maintenance of Healthy Thyroid Hormones, Antioxidant Support and Support Detoxification\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eSize: 60 Capsules\u003c\/p\u003e\n\u003cp\u003eRN Labs Selenium AUST L 389882\u003c\/p\u003e\n\u003cp\u003eRN Labs Selenium is part of the RN Labs Range of Practitioner Brand quality naturopathic medicines available for patients under the care of a practitioner.\u003c\/p\u003e\n\u003cp\u003eRN Labs was formerly named Research Nutrition.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #ff2a00;\"\u003eTo access RN Labs Selenium select the \u003ca href=\"#how-to-access\" title=\"How To Access RN Labs Naturopathic Medicines 10% off RRP | HealthMasters RN Labs\"\u003e\u003cspan style=\"text-decoration: underline;\"\u003eHow To Access tab\u003c\/span\u003e\u003c\/a\u003e for more information.\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eSummary\u003c\/h5\u003e\n\u003ch2\u003eSummary: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eRN Labs Selenium capsules help to prevent dietary selenium deficiency, for the maintenance of healthy thyroid hormones, antioxidant support and the support of detoxification processes.\u003c\/p\u003e\n\u003ch5\u003eIndications\u003c\/h5\u003e\n\u003ch2\u003eIndications: RN Labs Selenium\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSelenomethionine is an easily absorbed and utilised form of Selenium\u003c\/li\u003e\n\u003cli\u003eSupports healthy thyroid hormone metabolism\u003c\/li\u003e\n\u003cli\u003eassists activation of Thyroxine (T4) to Triiodothyronine (T3)\u003c\/li\u003e\n\u003cli\u003eSupports production of Glutathione for natural liver detoxification processes\u003c\/li\u003e\n\u003cli\u003eSupports antioxidant functions in the body\u003c\/li\u003e\n\u003cli\u003eas a cofactor for glutathione peroxidase activity\u003c\/li\u003e\n\u003cli\u003eSupports immune system defences\u003c\/li\u003e\n\u003cli\u003eassists inhibition of viral and bacterial infections\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eDosage\u003c\/h5\u003e\n\u003ch2\u003eDosage: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eAdults take 1 capsule per day, or as instructed by a healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eActive Ingredients\u003c\/h5\u003e\n\u003ch2\u003eActive Ingredients: \u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach Vegetarian Capsule Contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSelenomethionine\u003c\/td\u003e\n\u003ctd\u003e373micrograms\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEquiv. to elemental Selenium\u003c\/td\u003e\n\u003ctd\u003e150micrograms\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eExcipients: Leucine, Hypromellose (Capsule), Microcrystalline\u003c\/p\u003e\n\u003cp\u003eCellulose, Colloidal Anhydrous Silica.\u003c\/p\u003e\n\u003cp\u003eSuitable for vegans.\u003c\/p\u003e\n\u003ch5\u003eAllergen Information\u003c\/h5\u003e\n\u003ch2\u003eAllergen Information: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eRN Labs Selenium does NOT contain any wheat, gluten, dairy, lactose, egg, yeast, soy, artificial colours, artificial sweeteners, or artificial flavours.\u003c\/p\u003e\n\u003cp\u003eRN Labs Selenium also does not contain artificial preservatives, stearate lubricants and other commonly detrimental excipients\u003c\/p\u003e\n\u003ch5\u003eResearch Highlights\u003c\/h5\u003e\n\u003ch2\u003eResearch Highlights: RN Labs Selenium\u003c\/h2\u003e\n\u003ch3\u003eSelenomethionine Absorption\u003c\/h3\u003e\n\u003cp\u003eOne study measured the effects of different forms of Selenium on plasma biomarkers (including selenium concentration, selenoprotein P concentration, and glutathione peroxidase activity) as well as urinary selenium excretion. Supplementation with Selenomethionine, and high- Selenium yeast raised the plasma selenium concentration in a dose-dependant manner, whilst Selenite did not. The higher urinary selenium excretion or Selenomethionine, determined that this form is better absorbed than Selenite.\u003c\/p\u003e\n\u003cp\u003eA review found that organic Selenium forms (such as Selenomethionine) increased blood selenium concentration more rapidly and to a greater extent than inorganic forms (such as selenite or selenate).\u003c\/p\u003e\n\u003ch3\u003eAntioxidant Support\u003c\/h3\u003e\n\u003cp\u003eSelenium supplementation has demonstrated an effective increase in serum Selenium, and subsequently increasing the antioxidant enzyme Glutathione Peroxidase (GSH-Px) activity, for which Selenium is an essential component.\u003c\/p\u003e\n\u003cp\u003eSome long term studies have demonstrated that Selenium supplementation over a 24 week intervention period, was able to reduce the oxidation marker Malondyaldehyde (MDA), as well as increasing serum Glutathione. One study in particular, by Razavi and colleagues, found that in PCOS patients, Selenium supplementation for 8 weeks was effective in reducing MDA, inflammatory markers and also improved reproductive outcomes.\u003c\/p\u003e\n\u003ch3\u003eThyroid Hormone Metabolism\u003c\/h3\u003e\n\u003cp\u003eSelenium, as Selenoproteins, contribute to thyroid hormone biosynthesis and metabolism, antioxidant defence and control of redox processes in thyrocytes. Selenium has, in particular, a significant role in converting inactive thyroid hormone T4 to T3 to be utilised by the body.\u003c\/p\u003e\n\u003cp\u003eOne double-blind placebo-controlled trial by Olivieri et al, found a significant improvement of selenium indices, and a decrease in T4 following selenium supplementation. Compared with the placebo treated group, which found that serum selenium, erythrocyte glutathione peroxidase activity and thyroid hormones were unchanged. The authors concluded that selenium status influences thyroid hormones.\u003c\/p\u003e\n\u003cp\u003eA study by Kobayashi and colleagues, found that selenium supplementation in patients with abnormal thyroid levels, resulted in a significantly decreased TSH, FT4, and FT4\/FT3 ratio, and increased FT3.\u003c\/p\u003e\n\u003ch3\u003eSelenium as a Co-Factor\u003c\/h3\u003e\n\u003cp\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" alt=\"RN Labs Selenium- Selenium as a Co-Factor at HealthMasters RN Labs\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/RNLabsSelenium-SeleniumasaCo-FactoratHealthMastersRNLabs_1024x1024.png?v=1690446492\"\u003e\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: RN Labs Selenium\u003c\/h2\u003e\n\u003cp\u003eFOR PRACTITIONER DISPENSING ONLY.\u003c\/p\u003e\n\u003cp\u003eSafety has not been confirmed during pregnancy \u0026amp; lactation.\u003c\/p\u003e\n\u003cp\u003eSelenium is toxic in high doses, it is recommended that a daily dose of 150 micrograms for adults of selenium from dietary supplements not be exceeded.\u003c\/p\u003e\n\u003ch5\u003eQuality and Purity\u003c\/h5\u003e\n\u003ch2\u003eQuality and Purity: RN Labs Selenium\u003c\/h2\u003e\n\u003ch3\u003eRN Labs use only the highest grade ingredients and materials available. RN Labs' purity standards for manufacturing and sourcing are extensively researched and verified.\u003c\/h3\u003e\n\u003cp\u003eRN Labs Selenium is a pure and hypoallergenic product, developed to meet the needs of even the most sensitive patients.\u003c\/p\u003e\n\u003ch3\u003ePure and Free From\u003c\/h3\u003e\n\u003cp\u003eRN Labs Selenium is formulated with no harsh or irritating excipients, ensuring comfort, safety and efficacy for improved patient compliance and results.\u003c\/p\u003e\n\u003ch5\u003eThe RN Difference\u003c\/h5\u003e\n\u003ch2\u003eThe RN Labs Difference: \u003c\/h2\u003e\n\u003cstyle\u003e\u003c!--\n.embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; }\n--\u003e\u003c\/style\u003e\n\u003cdiv class=\"embed-container\"\u003e\u003ciframe src=\"https:\/\/player.vimeo.com\/video\/325810732\" allowfullscreen=\"\" mozallowfullscreen=\"\" webkitallowfullscreen=\"\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: \u003c\/h2\u003e\n\u003cp\u003eAdeoye et al, 2018, Review on the role of glutathione on oxidative stress and infertility, JBRA assisted reproduction.\u003c\/p\u003e\n\u003cp\u003eAgostoni C et al, 2014, Scientific Opinion on Dietary Reference Values for selenium, European Food Safety Authority Journal.\u003c\/p\u003e\n\u003cp\u003eBurk, RF et al, 2006, Effects of Chemical Form of Selenium on Plasma Biomarkers in a High-Dose Human Supplementation Trial, Cancer Epidemiology, Biomarkers \u0026amp; Prevention.\u003c\/p\u003e\n\u003cp\u003eDorea JG, 2002, Selenium and breast-feeding, The British Journal of Nutrition.\u003c\/p\u003e\n\u003cp\u003eKang et al, 1997, Effect of diet induced hypercholesterolemia and selenium supplementation in nitric oxide synthase activity. Archives of physiology and biochemistry.\u003c\/p\u003e\n\u003cp\u003eKawai et al, 2018, Thyroid hormone status in patients with severe selenium deficiency, Clinical Pediatric Endocrinology.\u003c\/p\u003e\n\u003cp\u003eKe et al, 2020, Reduced glutathione ameliorates liver function, oxidative stress and inflammation after interventional therapy for hepatocellular carcinoma. Journal of B.U.ON.\u003c\/p\u003e\n\u003cp\u003eKoboyashi et al, 2021, Thyroid function in patients with selenium deficiency exhibits high free T4 to T3 ratio, Clinical Pediatric Endocrinology.\u003c\/p\u003e\n\u003cp\u003eKöhrle et al, 2009, Selenium and Thyroid, Best practice \u0026amp; research.\u003c\/p\u003e\n\u003cp\u003eLook et al, 1997, Serum selenium, plasma glutathione (GSH) and erythrocyte glutathione peroxidase (GSH-Px) levels in asymptomatic versus symptomatic human immunodeficiency virus-1 (HIV-1)-infection. European Journal of Clinical Nutrition.\u003c\/p\u003e\n\u003cp\u003eMahmoodianfard et al, Effects of Zinc and Selenium Supplementation on Thyroid Function in Overweight and Obese Hypothyroid Female Patients: A Randomized Double-Blind Controlled Trial. Journal of the American College of Nutrition.\u003c\/p\u003e\n\u003cp\u003eMuri et al, 2020, Redox regulation of immunometabolism, Nature reviews. Immunology. Nève J, 1995, Human Selenium Supplementation as Assessed by Changes in Blood Selenium Concentration and Glutathione Peroxidase Activity, Journal of Trace Elements in Medicine and Biology.\u003c\/p\u003e\n\u003cp\u003eOlivieri O et al, 1995, Low Selenium Status in the Elderly Influences Thyroid Hormones, Clinical Science (London).\u003c\/p\u003e\n\u003cp\u003eOzturk et al, 2008, Comparison of plasma malondialdehyde glutathione, glutathione peroxidase, hydroxyproline and selenium levels in patients with vitiligo and healthy controls. Indian Journal of Dermatology.\u003c\/p\u003e\n\u003cp\u003eRazavi et al, 2016, Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome. Hormone and metabolic research.\u003c\/p\u003e\n\u003cp\u003eRohr-Udilova, 2012, Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. Hepatology.\u003c\/p\u003e\n\u003cp\u003eSalama, 2007, The role of selenium in critical illness: Basic science and clinical implications. Indian Journal of Critical Care Medicine\u003c\/p\u003e\n\u003cp\u003eSavory et al, 2012, Selenium supplementation and exercise: effect on oxidant stress in overweight adults. Obesity (Silver Spring).\u003c\/p\u003e\n\u003cp\u003eSteinbrenner et al, 2013, Toward Understanding Success and Failures in the Use of Selenium for Cancer Prevention. Antioxidants \u0026amp; Redox Signalling.\u003c\/p\u003e\n\u003cp\u003eShidfar, 2018, Regression of Non alcoholic Fatty Liver Disease with Zinc and Selenium Co-Supplementation after Disease Progression in Rats. Iranian journal of medical sciences.\u003c\/p\u003e\n\u003cp\u003eThomson et al, 1993, Long-term supplementation with selenate and selenomethionine: Selenium and glutathione peroxidase (EC 1.11.1.8) in blood components of New Zealand women. British Journal of Nutrition.\u003c\/p\u003e\n\u003cp\u003eXu et al, 2022, The Role and Mechanisms of Selenium Supplementation on Fatty Liver-Associated Disorder, Antioxidants.\u003c\/p\u003e\n\u003cp\u003eYun et al, 2007, NF-kappaB signaling pathway, not IFN-beta\/STAT1, is responsible for the selenium suppression of LPS-induced nitric oxide production. International immunopharmacology.\u003c\/p\u003e\n\u003cp\u003eZakeri et al, 2021, Selenium supplementation and oxidative stress: A review. PharmaNutrition\u003c\/p\u003e\n\u003cp\u003eSteinbrenner et. al. 2015. Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections. Adv Nutr. 6(1): 73–82\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}