{"id":8456065450214,"title":"RN Labs Bergasome +","handle":"rn-labs-bergasome-plus","description":"\u003ch2\u003eRN Labs Bergasome +\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eCholesterol Support\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003e(Formerly RN Labs Bergastat)\u003c\/p\u003e\n\u003cp\u003eSize: 60 Capsules\u003c\/p\u003e\n\u003cp\u003eRN Labs Bergasome + is part of the RN Labs Range of Practitioner Brand quality naturopathic medicines available for patients under the care of a practitioner.\u003c\/p\u003e\n\u003cp\u003eRN Labs was formerly named Research Nutrition.\u003c\/p\u003e\n\u003cp\u003eRN Labs Bergasome + for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCholesterol Support\u003c\/li\u003e\n\u003cli\u003eCardiovascular Support\u003c\/li\u003e\n\u003cli\u003eMetabolic Support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eRN Labs Bergasome + is Vegan\u003c\/p\u003e\n\u003cp\u003eRN Labs Bergasome + AUST L 416221\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #ff2a00;\"\u003eTo access RN Labs Bergasome + select the \u003ca title=\"How To Access RN Labs Naturopathic Medicines 10% off RRP | HealthMasters RN Labs\" href=\"#how-to-access\"\u003e\u003cspan style=\"text-decoration: underline;\"\u003eHow To Access tab\u003c\/span\u003e\u003c\/a\u003e for more information.\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eSummary\u003c\/h5\u003e\n\u003ch2\u003eSummary: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRN Labs Bergasome + combines proprietary Italian Bergamot extract formulated with enhanced Phytosome delivery technology, along with pure Globe Artichoke Extract for a powerful synergistic approach to managing healthy blood lipids.\u003c\/li\u003e\n\u003cli\u003eHealthy cholesterol support\u003c\/li\u003e\n\u003cli\u003eHealthy blood lipids (fats) support\u003c\/li\u003e\n\u003cli\u003eCardiovascular system health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eDetails\u003c\/h5\u003e\n\u003ch2\u003eDetails: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eThis scientifically studied formula has been shown in clinical trials to reduce serum cholesterol and improve blood markers of lipid metabolism, while also supporting liver function.\u003c\/p\u003e\n\u003cp\u003eBergamot phyto-phospholipid is synergistically paired with Artichoke extract for maximum efficacy, to assist in the maintenance of healthy Cholesterol and support overall cardiovascular system health.\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eScientifically proven formula\u003c\/li\u003e\n\u003cli\u003eInnovative approach to cholesterol management\u003c\/li\u003e\n\u003cli\u003eCalabrian sourced Bergamot juice extract (delivers unique polyphenol actives)\u003c\/li\u003e\n\u003cli\u003ePhytosome form ensures maximum absorption\u003c\/li\u003e\n\u003cli\u003eSynergistic blend provides optimised efficacy\u003c\/li\u003e\n\u003cli\u003eWorks via natural body processes\u003c\/li\u003e\n\u003cli\u003eHelps maintain healthy blood lipids\u003c\/li\u003e\n\u003cli\u003eSupports cardiovascular system health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/chrome_Pk7D9b6Xwa_1024x1024.png?v=1709017152\" alt=\"RN Labs Bergastat 10% off RRP | HealthMasters RN Labs Actions\"\u003e\u003c\/p\u003e\n\u003ch5\u003eDosage\u003c\/h5\u003e\n\u003ch2\u003eDosage: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003e1-2 capsules once or twice daily.\u003c\/p\u003e\n\u003cp\u003eTypically 2 capsules twice daily for acute interventions.\u003c\/p\u003e\n\u003cp\u003e3-4 capsules per day may be taken in cases proving resistant to treatment after subsequent testing.\u003c\/p\u003e\n\u003cp\u003e1 capsule per day may be sufficient as a maintenance dose in some individuals.\u003c\/p\u003e\n\u003ch5\u003eActive Ingredients\u003c\/h5\u003e\n\u003ch2\u003eActive Ingredients: RN Labs Bergasome +\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach Vegetarian Capsule Contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVazguard Bergamot Phytosome\u003c\/td\u003e\n\u003ctd\u003e500mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003econtaining Citrus limon (Lemon) (Bergamot)\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003efruit juice extract dry concentrate\u003c\/td\u003e\n\u003ctd\u003e200mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003efrom Citus limon (Bergamot) fresh fruit juice\u003c\/td\u003e\n\u003ctd\u003e12g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003estandardised to contain total Flavones\u003c\/td\u003e\n\u003ctd\u003e80mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCynara scolymus dry leaf extract concentrate\u003c\/td\u003e\n\u003ctd\u003e100mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003efrom dry Cynara scolymus (Globe Artichoke) leaf\u003c\/td\u003e\n\u003ctd\u003e1g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eLeucine, Microcrystalline Cellulose, Hypromellose (Capsule), Lecithin (Sunflower), Medium Chain Triglycerides, Acacia, Maltodextrin (Corn), Liquid Glucose, Colloidal Anhydrous Silica.\u003c\/p\u003e\n\u003ch5\u003eAllergen Information\u003c\/h5\u003e\n\u003ch2\u003eAllergen Information: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRN Labs Bergastat does NOT contain any wheat, gluten, dairy, lactose, egg, yeast, soy, artificial colours, artificial sweeteners, or artificial flavours.\u003c\/li\u003e\n\u003cli\u003eRN Labs Bergastat also does not contain artificial preservatives, stearate lubricants and other commonly detrimental excipients.\u003c\/li\u003e\n\u003cli\u003eSuitable for vegans.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eFAQs\u003c\/h5\u003e\n\u003ch2\u003eFAQs: RN Labs Bergasome +\u003c\/h2\u003e\n\u003ch3\u003eWhy does Bergastat contain Glucose?\u003c\/h3\u003e\n\u003cp\u003eA very small amount of glucose is used by Indena in the production of their proprietary Bergamot Phytosome (Vazguard).\u003c\/p\u003e\n\u003cp\u003eA further small amount of pure corn maltodextrin is used in the preparation of high quality standardised Globe Artichoke extract.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRN Labs has not added any further carbohydrate sources in the process of formulating these specialised ingredients into a finished product.\u003c\/p\u003e\n\u003ch3\u003eIs Bergasome + suitable for Carbohydrate Sensitive patients?\u003c\/h3\u003e\n\u003cp\u003eRN Labs has specifically formulated Bergastat for those seeking to achieve metabolic control, including those impacted by dietary sugars, carbohydrates and lipids.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThe extremely small residual quantities of glucose and maltodextrin that are introduced by the use of such high quality ingredients are not expected to be capable of stimulating any adverse increases of insulin, nor disrupting blood sugar or ketone levels, when taking Bergastat at typical doses.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRN Labs takes pride in not only sourcing the highest quality ingredients, but also providing full label transparency and a higher level of ingredient detail than is conventionally required of supplement companies, to help practitioners and patients make fully informed decisions for their health, and achieve the highest levels of clinical efficacy.\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eResearch\u003c\/h5\u003e\n\u003ch2\u003eResearch: RN Labs Bergasome +\u003c\/h2\u003e\n\u003ch3\u003eCALABRIAN BERGAMOT JUICE EXTRACT\u003c\/h3\u003e\n\u003cp\u003eFormisano et al (2019) sought to identify the active polyphenols in Bergamot and found a wide array of previously unidentified compounds in the juice of Calabrian Bergamot (not found in other non-juice Bergamot extracts).\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eHeightened clinical activity was demonstrated from these flavone compounds, making Calabrian Bergamot juice extracts the preferred form of Bergamot supplementation for metabolic purposes.\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eGLOBE ARTICHOKE LEAF EXTRACT\u003c\/h3\u003e\n\u003cp\u003eCynara scolymus (Globe Artichoke) extracts have been shown in numerous studies (as reviewed by Sahebkar et al 2018) to possess plasma lipid lowering effects (especially of LDL, while sparing HDL – demonstrating direct metabolic actions).\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eAuthors such as Mocelin et al (2016) have also studied these effects in comparison to statin medications in animals, and found lower markers of inflammation (such as IL-6 and TNF-a), further contributing to antiatherogenic potential, and ultimately attributed these metabolic actions to the unique array of polar flavanoid compounds present in high quality Artichoke extracts.\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eBERGAMOT + ARTICHOKE FOR LOWERING CHOLESTEROL ROL\u003c\/h3\u003e\n\u003cp\u003eRiva et al (2022) conducted a randomised, placebo-controlled trial investigating natural alternatives for reducing hypercholesterolemia. The researchers found that the combined use of Bergamot Phytosome® with Artichoke extract enhanced clinical outcomes.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThe supplemented group exhibited significant reductions in total and LDL cholesterol compared to the placebo group. Notably, even individuals who did not follow a low-calorie diet showed improvements including reduced waist circumference, indicative of visceral adipose tissue.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThis study showed that a small subset of the population are non-responders to Bergamot alone and required the addition of Artichoke extract to receive the full benefit from Bergamot supplementation.\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"RN Labs Bergastat 10% off RRP | HealthMasters RN Labs Lowering Cholesterol\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/chrome_XRICUCKPAX_1024x1024.png?v=1709019443\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003ch3\u003eReducing Visceral Adiposiy\u003c\/h3\u003e\n\u003cp\u003eA recent study conducted by Rondanelli et al. (2020) explored the impact of Bergamot Phytosome on Visceral Adipose Tissue (VAT) and metabolic profile in overweight and obese individuals with mild hypercholesterolemia. The 30 day randomised placebo-controlled trial resulted in the Bergamot Phytosome group experiencing significant reductions in VAT, total cholesterol, and LDL-cholesterol compared to the placebo group.\u003c\/p\u003e\n\u003cp\u003eThis highlights the benefits of Bergamot extract to support patients presenting with dyslipidaemia and complications of metabolic syndrome.\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"RN Labs Bergastat 10% off RRP | HealthMasters RN Labs Reducint VAT\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/chrome_6hfkdhJ57z_600x600.png?v=1709019233\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003ch3\u003eImproving NAFLD Markers\u003c\/h3\u003e\n\u003cp\u003eBergamot extracts have been studied for their effects on hypercholesterolaemia, and fatty liver.\u003c\/p\u003e\n\u003cp\u003eIn a study investigating dietary supplementation, researchers investigated a formula containing Bergamot Phytosome and Globe Artichoke extract in 60 healthy individuals with polygenic hypercholesterolemia. After a one-month low-fat Mediterranean diet, participants took the formula or a placebo for 8 weeks. Results showed a significant improvement in lipid profiles, reduced inflammation, and positive effects on NAFLD markers (Fogacci et al, 2022).\u003c\/p\u003e\n\u003cp\u003eBergamot Phytosome® supplementation therefore presents a unique opportunity to support cholesterol and lipid management, without negatively impacting liver function.\u003c\/p\u003e\n\u003cp\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/chrome_Pk7D9b6Xwa_1024x1024.png?v=1709017152\" alt=\"RN Labs Bergastat 10% off RRP | HealthMasters Rn Labs Bergamont Actions\"\u003e\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eFOR PRACTITIONER DISPENSING ONLY.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eIf symptoms persist consult your healthcare practitioner.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin and\/or mineral supplements should not replace a balanced diet.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eSafety has not been confirmed during pregnancy \u0026amp; lactation.\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eKNOWN SIDE EFFECTS\u003c\/h3\u003e\n\u003cp\u003eBergastat is considered to be well tolerated within typical dosage ranges.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRN Labs use only the highest grade ingredients and materials available. Our purity standards for manufacturing and sourcing are extensively researched and verified.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eStore below 25⁰C in a cool, dry, dark place.\u003c\/p\u003e\n\u003ch5\u003eQuality and Purity\u003c\/h5\u003e\n\u003ch2\u003eQuality and Purity: \u003c\/h2\u003e\n\u003ch3\u003eRN Labs use only the highest grade ingredients and materials available. RN Labs' purity standards for manufacturing and sourcing are extensively researched and verified.\u003c\/h3\u003e\n\u003cp\u003eRN Labs Bergastat is a pure and hypoallergenic product, developed to meet the needs of even the most sensitive patients.\u003c\/p\u003e\n\u003ch3\u003ePure and Free From\u003c\/h3\u003e\n\u003cp\u003eRN Labs Bergastat is formulated with no harsh or irritating excipients, ensuring comfort, safety and efficacy for improved patient compliance and results.\u003c\/p\u003e\n\u003ch5\u003eThe RN Difference\u003c\/h5\u003e\n\u003ch2\u003eThe RN Labs Difference: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cstyle\u003e\u003c!--\n.embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; }\n--\u003e\u003c\/style\u003e\n\u003cdiv class=\"embed-container\"\u003e\u003ciframe src=\"https:\/\/player.vimeo.com\/video\/325810732\" frameborder=\"0\" webkitallowfullscreen=\"\" mozallowfullscreen=\"\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eDi Donna L. et al (2009). Statin-like principles of bergamot fruit (Citrus bergamia): isolation of 3-hydroxymethylglutaryl flavonoid glycosides. Journal of natural products.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eFogacci F (2022). Effect of Dietary Supplementation with Eufortyn® Colesterolo Plus on Serum Lipids, Endothelial Reactivity, Indexes of Non Alcoholic Fatty Liver Disease and Systemic Inflammation in Healthy Subjects with Polygenic Hypercholesterolemia: The ANEMONE Study, Nutrients, vol. 14, no. 10, pp. 2099\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eFormisano C et al (2019). Detailed Phytochemical Characterization of Bergamot Polyphenolic Fraction (BPF) by UPLC-DAD-MS and LC-NMR. American Chemical Society.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eMonica Leopoldini et al. (2010). On the Inhibitor Effects of Bergamot Juice Flavonoids Binding to the 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Enzyme. Journal of Agricultural and Food Chemistry\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eNauman MC \u0026amp; Johnson JJ (2019). Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers. Integrative food, nutrition and metabolism.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003ePu P, et al. (2012). Naringin ameliorates metabolic syndrome by activating AMPactivated protein kinase in mice fed a high-fat diet. Archives of biochemistry and biophysics.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eQu H, et al. (2018). The effect of statin treatment on circulating coenzyme Q10 concentrations: an updated meta-analysis of randomized controlled trials. Eur J Med Res.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRiva A, (2021). Artichoke and Bergamot Phytosome Alliance: A Randomized Double Blind Clinical Trial in Mild Hypercholesterolemia, Nutrients, vol. 14, no. 1, pp. 108\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRondanelli M, et al (2021). Bergamot phytosome improved visceral fat and plasma lipid profiles in overweight and obese class I subject with mild\u003cbr\u003ehypercholesterolemia: A randomized placebo-controlled trial, Phytotherapy Research, vol. 35, no. 4, pp, 2045-2056\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eSui GG. et al (2018). Naringin Activates AMPK Resulting in Altered Expression of SREBPs, PCSK9, and LDLR To Reduce Body Weight in Obese C57BL\/6J Mice. Journal of agricultural and food chemistry.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eZheng Y, et al (2022). Effect of Bergamot and Laoxianghuang Polysaccharides on Gut Microbiota Derived from Patients with Hyperlipidemia: An Integrative Analysis of Microbiome and Metabolome during In Vitro Fermentation. Foods.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eAmirhossein Sahebkar, Matteo Pirro, Maciej Banach, Dimitri P Mikhailidis, Stephen L Atkin, Arrigo F G Cicero. 2018 . Lipid-lowering activity of artichoke extracts: A systematic review and meta-analysis\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRicieri Mocelin a, Matheus Marcon a, Glaucia D. Santo a, Leila Zanatta a, Adrieli Sachett b, Amanda P. Schönell b, Fernanda Bevilaqua b, Marta Giachini b, Rafael Chitolina b, Silvana M. Wildner b, Marta M.M.F. Duarte c, Greicy M.M. Conterato d, Angelo L. Piato e, Denise B. Gomes f, Walter A. Roman Junior. 2016. Hypolipidemic and antiatherogenic effects of Cynara scolymus in cholesterol-fed rats.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2024-02-27T18:01:39+11:00","created_at":"2024-02-27T16:03:04+11:00","vendor":"RN Labs","type":"RN Labs Naturopathic Medicines","tags":["CardioMetabolic","Cardiovascular","Naturopathic","RN Labs"],"price":5940,"price_min":5940,"price_max":5940,"available":true,"price_varies":false,"compare_at_price":6600,"compare_at_price_min":6600,"compare_at_price_max":6600,"compare_at_price_varies":false,"variants":[{"id":44336092840166,"title":"60 Capsules","option1":"60 Capsules","option2":null,"option3":null,"sku":"RNLBergasome60C","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"RN Labs Bergasome + - 60 Capsules","public_title":"60 Capsules","options":["60 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Bergasome + 10% off RRP at HealthMasters RN Labs Logo","id":33142115664102,"position":3,"preview_image":{"aspect_ratio":3.0,"height":100,"width":300,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/RNLabsLogo_cd9d7730-7ee1-4be8-8038-e616139a0abf.jpg?v=1723186769"},"aspect_ratio":3.0,"height":100,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/RNLabsLogo_cd9d7730-7ee1-4be8-8038-e616139a0abf.jpg?v=1723186769","width":300}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch2\u003eRN Labs Bergasome +\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eCholesterol Support\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003e(Formerly RN Labs Bergastat)\u003c\/p\u003e\n\u003cp\u003eSize: 60 Capsules\u003c\/p\u003e\n\u003cp\u003eRN Labs Bergasome + is part of the RN Labs Range of Practitioner Brand quality naturopathic medicines available for patients under the care of a practitioner.\u003c\/p\u003e\n\u003cp\u003eRN Labs was formerly named Research Nutrition.\u003c\/p\u003e\n\u003cp\u003eRN Labs Bergasome + for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCholesterol Support\u003c\/li\u003e\n\u003cli\u003eCardiovascular Support\u003c\/li\u003e\n\u003cli\u003eMetabolic Support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eRN Labs Bergasome + is Vegan\u003c\/p\u003e\n\u003cp\u003eRN Labs Bergasome + AUST L 416221\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #ff2a00;\"\u003eTo access RN Labs Bergasome + select the \u003ca title=\"How To Access RN Labs Naturopathic Medicines 10% off RRP | HealthMasters RN Labs\" href=\"#how-to-access\"\u003e\u003cspan style=\"text-decoration: underline;\"\u003eHow To Access tab\u003c\/span\u003e\u003c\/a\u003e for more information.\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eSummary\u003c\/h5\u003e\n\u003ch2\u003eSummary: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRN Labs Bergasome + combines proprietary Italian Bergamot extract formulated with enhanced Phytosome delivery technology, along with pure Globe Artichoke Extract for a powerful synergistic approach to managing healthy blood lipids.\u003c\/li\u003e\n\u003cli\u003eHealthy cholesterol support\u003c\/li\u003e\n\u003cli\u003eHealthy blood lipids (fats) support\u003c\/li\u003e\n\u003cli\u003eCardiovascular system health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eDetails\u003c\/h5\u003e\n\u003ch2\u003eDetails: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eThis scientifically studied formula has been shown in clinical trials to reduce serum cholesterol and improve blood markers of lipid metabolism, while also supporting liver function.\u003c\/p\u003e\n\u003cp\u003eBergamot phyto-phospholipid is synergistically paired with Artichoke extract for maximum efficacy, to assist in the maintenance of healthy Cholesterol and support overall cardiovascular system health.\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eScientifically proven formula\u003c\/li\u003e\n\u003cli\u003eInnovative approach to cholesterol management\u003c\/li\u003e\n\u003cli\u003eCalabrian sourced Bergamot juice extract (delivers unique polyphenol actives)\u003c\/li\u003e\n\u003cli\u003ePhytosome form ensures maximum absorption\u003c\/li\u003e\n\u003cli\u003eSynergistic blend provides optimised efficacy\u003c\/li\u003e\n\u003cli\u003eWorks via natural body processes\u003c\/li\u003e\n\u003cli\u003eHelps maintain healthy blood lipids\u003c\/li\u003e\n\u003cli\u003eSupports cardiovascular system health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/chrome_Pk7D9b6Xwa_1024x1024.png?v=1709017152\" alt=\"RN Labs Bergastat 10% off RRP | HealthMasters RN Labs Actions\"\u003e\u003c\/p\u003e\n\u003ch5\u003eDosage\u003c\/h5\u003e\n\u003ch2\u003eDosage: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003e1-2 capsules once or twice daily.\u003c\/p\u003e\n\u003cp\u003eTypically 2 capsules twice daily for acute interventions.\u003c\/p\u003e\n\u003cp\u003e3-4 capsules per day may be taken in cases proving resistant to treatment after subsequent testing.\u003c\/p\u003e\n\u003cp\u003e1 capsule per day may be sufficient as a maintenance dose in some individuals.\u003c\/p\u003e\n\u003ch5\u003eActive Ingredients\u003c\/h5\u003e\n\u003ch2\u003eActive Ingredients: RN Labs Bergasome +\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach Vegetarian Capsule Contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVazguard Bergamot Phytosome\u003c\/td\u003e\n\u003ctd\u003e500mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003econtaining Citrus limon (Lemon) (Bergamot)\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003efruit juice extract dry concentrate\u003c\/td\u003e\n\u003ctd\u003e200mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003efrom Citus limon (Bergamot) fresh fruit juice\u003c\/td\u003e\n\u003ctd\u003e12g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003estandardised to contain total Flavones\u003c\/td\u003e\n\u003ctd\u003e80mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCynara scolymus dry leaf extract concentrate\u003c\/td\u003e\n\u003ctd\u003e100mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 40px;\"\u003efrom dry Cynara scolymus (Globe Artichoke) leaf\u003c\/td\u003e\n\u003ctd\u003e1g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eLeucine, Microcrystalline Cellulose, Hypromellose (Capsule), Lecithin (Sunflower), Medium Chain Triglycerides, Acacia, Maltodextrin (Corn), Liquid Glucose, Colloidal Anhydrous Silica.\u003c\/p\u003e\n\u003ch5\u003eAllergen Information\u003c\/h5\u003e\n\u003ch2\u003eAllergen Information: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRN Labs Bergastat does NOT contain any wheat, gluten, dairy, lactose, egg, yeast, soy, artificial colours, artificial sweeteners, or artificial flavours.\u003c\/li\u003e\n\u003cli\u003eRN Labs Bergastat also does not contain artificial preservatives, stearate lubricants and other commonly detrimental excipients.\u003c\/li\u003e\n\u003cli\u003eSuitable for vegans.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eFAQs\u003c\/h5\u003e\n\u003ch2\u003eFAQs: RN Labs Bergasome +\u003c\/h2\u003e\n\u003ch3\u003eWhy does Bergastat contain Glucose?\u003c\/h3\u003e\n\u003cp\u003eA very small amount of glucose is used by Indena in the production of their proprietary Bergamot Phytosome (Vazguard).\u003c\/p\u003e\n\u003cp\u003eA further small amount of pure corn maltodextrin is used in the preparation of high quality standardised Globe Artichoke extract.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRN Labs has not added any further carbohydrate sources in the process of formulating these specialised ingredients into a finished product.\u003c\/p\u003e\n\u003ch3\u003eIs Bergasome + suitable for Carbohydrate Sensitive patients?\u003c\/h3\u003e\n\u003cp\u003eRN Labs has specifically formulated Bergastat for those seeking to achieve metabolic control, including those impacted by dietary sugars, carbohydrates and lipids.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThe extremely small residual quantities of glucose and maltodextrin that are introduced by the use of such high quality ingredients are not expected to be capable of stimulating any adverse increases of insulin, nor disrupting blood sugar or ketone levels, when taking Bergastat at typical doses.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRN Labs takes pride in not only sourcing the highest quality ingredients, but also providing full label transparency and a higher level of ingredient detail than is conventionally required of supplement companies, to help practitioners and patients make fully informed decisions for their health, and achieve the highest levels of clinical efficacy.\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eResearch\u003c\/h5\u003e\n\u003ch2\u003eResearch: RN Labs Bergasome +\u003c\/h2\u003e\n\u003ch3\u003eCALABRIAN BERGAMOT JUICE EXTRACT\u003c\/h3\u003e\n\u003cp\u003eFormisano et al (2019) sought to identify the active polyphenols in Bergamot and found a wide array of previously unidentified compounds in the juice of Calabrian Bergamot (not found in other non-juice Bergamot extracts).\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eHeightened clinical activity was demonstrated from these flavone compounds, making Calabrian Bergamot juice extracts the preferred form of Bergamot supplementation for metabolic purposes.\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eGLOBE ARTICHOKE LEAF EXTRACT\u003c\/h3\u003e\n\u003cp\u003eCynara scolymus (Globe Artichoke) extracts have been shown in numerous studies (as reviewed by Sahebkar et al 2018) to possess plasma lipid lowering effects (especially of LDL, while sparing HDL – demonstrating direct metabolic actions).\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eAuthors such as Mocelin et al (2016) have also studied these effects in comparison to statin medications in animals, and found lower markers of inflammation (such as IL-6 and TNF-a), further contributing to antiatherogenic potential, and ultimately attributed these metabolic actions to the unique array of polar flavanoid compounds present in high quality Artichoke extracts.\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eBERGAMOT + ARTICHOKE FOR LOWERING CHOLESTEROL ROL\u003c\/h3\u003e\n\u003cp\u003eRiva et al (2022) conducted a randomised, placebo-controlled trial investigating natural alternatives for reducing hypercholesterolemia. The researchers found that the combined use of Bergamot Phytosome® with Artichoke extract enhanced clinical outcomes.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThe supplemented group exhibited significant reductions in total and LDL cholesterol compared to the placebo group. Notably, even individuals who did not follow a low-calorie diet showed improvements including reduced waist circumference, indicative of visceral adipose tissue.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThis study showed that a small subset of the population are non-responders to Bergamot alone and required the addition of Artichoke extract to receive the full benefit from Bergamot supplementation.\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"RN Labs Bergastat 10% off RRP | HealthMasters RN Labs Lowering Cholesterol\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/chrome_XRICUCKPAX_1024x1024.png?v=1709019443\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003ch3\u003eReducing Visceral Adiposiy\u003c\/h3\u003e\n\u003cp\u003eA recent study conducted by Rondanelli et al. (2020) explored the impact of Bergamot Phytosome on Visceral Adipose Tissue (VAT) and metabolic profile in overweight and obese individuals with mild hypercholesterolemia. The 30 day randomised placebo-controlled trial resulted in the Bergamot Phytosome group experiencing significant reductions in VAT, total cholesterol, and LDL-cholesterol compared to the placebo group.\u003c\/p\u003e\n\u003cp\u003eThis highlights the benefits of Bergamot extract to support patients presenting with dyslipidaemia and complications of metabolic syndrome.\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"RN Labs Bergastat 10% off RRP | HealthMasters RN Labs Reducint VAT\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/chrome_6hfkdhJ57z_600x600.png?v=1709019233\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003ch3\u003eImproving NAFLD Markers\u003c\/h3\u003e\n\u003cp\u003eBergamot extracts have been studied for their effects on hypercholesterolaemia, and fatty liver.\u003c\/p\u003e\n\u003cp\u003eIn a study investigating dietary supplementation, researchers investigated a formula containing Bergamot Phytosome and Globe Artichoke extract in 60 healthy individuals with polygenic hypercholesterolemia. After a one-month low-fat Mediterranean diet, participants took the formula or a placebo for 8 weeks. Results showed a significant improvement in lipid profiles, reduced inflammation, and positive effects on NAFLD markers (Fogacci et al, 2022).\u003c\/p\u003e\n\u003cp\u003eBergamot Phytosome® supplementation therefore presents a unique opportunity to support cholesterol and lipid management, without negatively impacting liver function.\u003c\/p\u003e\n\u003cp\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/chrome_Pk7D9b6Xwa_1024x1024.png?v=1709017152\" alt=\"RN Labs Bergastat 10% off RRP | HealthMasters Rn Labs Bergamont Actions\"\u003e\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eFOR PRACTITIONER DISPENSING ONLY.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eIf symptoms persist consult your healthcare practitioner.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin and\/or mineral supplements should not replace a balanced diet.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eSafety has not been confirmed during pregnancy \u0026amp; lactation.\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eKNOWN SIDE EFFECTS\u003c\/h3\u003e\n\u003cp\u003eBergastat is considered to be well tolerated within typical dosage ranges.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRN Labs use only the highest grade ingredients and materials available. Our purity standards for manufacturing and sourcing are extensively researched and verified.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eStore below 25⁰C in a cool, dry, dark place.\u003c\/p\u003e\n\u003ch5\u003eQuality and Purity\u003c\/h5\u003e\n\u003ch2\u003eQuality and Purity: \u003c\/h2\u003e\n\u003ch3\u003eRN Labs use only the highest grade ingredients and materials available. RN Labs' purity standards for manufacturing and sourcing are extensively researched and verified.\u003c\/h3\u003e\n\u003cp\u003eRN Labs Bergastat is a pure and hypoallergenic product, developed to meet the needs of even the most sensitive patients.\u003c\/p\u003e\n\u003ch3\u003ePure and Free From\u003c\/h3\u003e\n\u003cp\u003eRN Labs Bergastat is formulated with no harsh or irritating excipients, ensuring comfort, safety and efficacy for improved patient compliance and results.\u003c\/p\u003e\n\u003ch5\u003eThe RN Difference\u003c\/h5\u003e\n\u003ch2\u003eThe RN Labs Difference: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cstyle\u003e\u003c!--\n.embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; }\n--\u003e\u003c\/style\u003e\n\u003cdiv class=\"embed-container\"\u003e\u003ciframe src=\"https:\/\/player.vimeo.com\/video\/325810732\" frameborder=\"0\" webkitallowfullscreen=\"\" mozallowfullscreen=\"\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: RN Labs Bergasome +\u003c\/h2\u003e\n\u003cp\u003eDi Donna L. et al (2009). Statin-like principles of bergamot fruit (Citrus bergamia): isolation of 3-hydroxymethylglutaryl flavonoid glycosides. Journal of natural products.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eFogacci F (2022). Effect of Dietary Supplementation with Eufortyn® Colesterolo Plus on Serum Lipids, Endothelial Reactivity, Indexes of Non Alcoholic Fatty Liver Disease and Systemic Inflammation in Healthy Subjects with Polygenic Hypercholesterolemia: The ANEMONE Study, Nutrients, vol. 14, no. 10, pp. 2099\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eFormisano C et al (2019). Detailed Phytochemical Characterization of Bergamot Polyphenolic Fraction (BPF) by UPLC-DAD-MS and LC-NMR. American Chemical Society.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eMonica Leopoldini et al. (2010). On the Inhibitor Effects of Bergamot Juice Flavonoids Binding to the 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Enzyme. Journal of Agricultural and Food Chemistry\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eNauman MC \u0026amp; Johnson JJ (2019). Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers. Integrative food, nutrition and metabolism.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003ePu P, et al. (2012). Naringin ameliorates metabolic syndrome by activating AMPactivated protein kinase in mice fed a high-fat diet. Archives of biochemistry and biophysics.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eQu H, et al. (2018). The effect of statin treatment on circulating coenzyme Q10 concentrations: an updated meta-analysis of randomized controlled trials. Eur J Med Res.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRiva A, (2021). Artichoke and Bergamot Phytosome Alliance: A Randomized Double Blind Clinical Trial in Mild Hypercholesterolemia, Nutrients, vol. 14, no. 1, pp. 108\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRondanelli M, et al (2021). Bergamot phytosome improved visceral fat and plasma lipid profiles in overweight and obese class I subject with mild\u003cbr\u003ehypercholesterolemia: A randomized placebo-controlled trial, Phytotherapy Research, vol. 35, no. 4, pp, 2045-2056\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eSui GG. et al (2018). Naringin Activates AMPK Resulting in Altered Expression of SREBPs, PCSK9, and LDLR To Reduce Body Weight in Obese C57BL\/6J Mice. Journal of agricultural and food chemistry.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eZheng Y, et al (2022). Effect of Bergamot and Laoxianghuang Polysaccharides on Gut Microbiota Derived from Patients with Hyperlipidemia: An Integrative Analysis of Microbiome and Metabolome during In Vitro Fermentation. Foods.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eAmirhossein Sahebkar, Matteo Pirro, Maciej Banach, Dimitri P Mikhailidis, Stephen L Atkin, Arrigo F G Cicero. 2018 . Lipid-lowering activity of artichoke extracts: A systematic review and meta-analysis\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eRicieri Mocelin a, Matheus Marcon a, Glaucia D. Santo a, Leila Zanatta a, Adrieli Sachett b, Amanda P. Schönell b, Fernanda Bevilaqua b, Marta Giachini b, Rafael Chitolina b, Silvana M. Wildner b, Marta M.M.F. Duarte c, Greicy M.M. Conterato d, Angelo L. Piato e, Denise B. Gomes f, Walter A. Roman Junior. 2016. Hypolipidemic and antiatherogenic effects of Cynara scolymus in cholesterol-fed rats.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}