{"id":2288396533819,"title":"BioCeuticals MTHF 60 caps","handle":"bioceuticals-mthf-60-caps","description":"\u003ch3\u003e\u003cem\u003eBiologically Active Folate\u003c\/em\u003e\u003c\/h3\u003e\n\u003ch2\u003eBioCeuticals MTHF 60 caps\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBioCeuticals MTHF 5-methyltetrahydrofolate (5-MTHF) is the most active metabolite of folic acid, bypassing all of the enzymatic activation steps in the conversion of folic acid to the biologically active 5-MTHF.\u003c\/li\u003e\n\u003cli\u003eDirectly utilised by the body, 5-MTHF supports healthy methylation, homocysteine metabolism, DNA replication and foetal development.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eServing Type: Capsule\u003c\/p\u003e\n\u003cp\u003eAvailable In Sizes: 60 capsules\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBioCeuticals MTHF has No Added Dairy, No Added Gluten, No Added Shellfish, No Added Soy Protein, No Added Yeast.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBioCeuticals MTHF is Pregnancy Friendly, Vegan Friendly, Vegetarian Friendly.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eBioCeuticals MTHF conditions associated: Women's Health, Cognitive Health, Cardiovascular Health, Pregnancy Health, Nervous System\u003c\/p\u003e\n\u003cp\u003eBioCeuticals MTHF AUST L 260279\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioCeuticals MTHF\u003c\/h2\u003e\n\u003cp\u003eAdults: Take 1 capsule daily or as directed by your healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eFeatures\u003c\/h5\u003e\n\u003ch2\u003eFeatures: BioCeuticals MTHF\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eContains 5-MTHF, the most active form of folic acid.\u003c\/li\u003e\n\u003cli\u003eSupports a healthy brain and nervous system function.\u003c\/li\u003e\n\u003cli\u003eSupports healthy methylation pathways and homocysteine metabolism.\u003c\/li\u003e\n\u003cli\u003eIs involved in growth and cellular replication, and supports healthy replication of DNA through healthy DNA methylation.\u003c\/li\u003e\n\u003cli\u003eProvides 500mcg of 5-MTHF (active folate), which contributes to the normal growth of the foetus.\u003c\/li\u003e\n\u003cli\u003eIf taken daily for one month before conception and during pregnancy, may reduce the risk of women having a child with birth defects of the brain and\/or spinal cord such as the neural tube defects known as spina bifida and anencephaly.\u003c\/li\u003e\n\u003cli\u003eHelps maintain normal blood by helping to form red blood cells and assisting with their function.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioCeuticals MTHF\u003c\/h2\u003e\n\u003ctable width='100%\"'\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach capsule contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLevomefolate calcium\u003c\/td\u003e\n\u003ctd\u003e541.4mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. 5-MTHF (active folate)\u003c\/td\u003e\n\u003ctd\u003e500mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: BioCeuticals MTHF\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003e5-methyltetrahydrofolate (5-MTHF)\u003c\/em\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e5-MTHF is the active metabolite of folic acid. It does not require the enzymes dihydrofolate reductase (DHFR) or methylenetetrahydrofolate reductase (MTHFR) in order to participate in reactions utilising folates as a source of one-carbon moieties.\u003c\/li\u003e\n\u003cli\u003eFolic acid is converted to dihydrofolate (DHF) by DHF reductase (DHFR) and then tetrahydrofolate (THF). Folinic acid (5-formyl THF) is rapidly metabolised via 5,10-methylenetetrahydrofolate (5,10-MTHF), which is then converted to 5-methyltetrahydrofolate (5-MTHF). See Figure 1.\u003c\/li\u003e\n\u003cli\u003e5-MTHF can in turn be metabolised by other pathways back to 5,10-MTHF, which is converted to 5-MTHF by an irreversible enzyme MTHFR catalysed reduction using the cofactors FADH2 and NADPH.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: BioCeuticals MTHF\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eIf symptoms persist consult your healthcare practitioner.\u003c\/li\u003e\n\u003cli\u003eDo not exceed the stated dose except on medical advice.\u003c\/li\u003e\n\u003cli\u003eIf you have had a baby with neural tube defect\/spina bifida, seek medical advice.\u003c\/li\u003e\n\u003cli\u003eVitamin supplements should not replace a balanced diet.\u003c\/li\u003e\n\u003cli\u003eAlways read the label. Use only as directed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: BioCeuticals MTHF\u003c\/h2\u003e\n\u003cp\u003e[1] Fava M, Mischoulon D. Folate in depression: efficacy, safety, differences in formulation, and clinical issues. J Clin Psychiatry 2009;70(suppl 5):12-17.\u003c\/p\u003e\n\u003cp\u003e[2] Braun L, Cohen M. Herbs and natural supplements: an evidence-based guide, 3rd ed. Sydney: Churchill Livingstone Elsevier, 2010.\u003c\/p\u003e\n\u003cp\u003e[3] Folic acid\/5'-MTHF. Natural Medicines Comprehensive Database. Viewed 10 Nov 2015, www.naturaldatabase.com\u003c\/p\u003e\n\u003cp\u003e[4] 5-methyltetrahydrofolate monograph. AMR 2005;10(4):330-337.\u003c\/p\u003e\n\u003cp\u003e[5] Gutstein S, Bernstein LH, Levy L, et al. Failure of response to N5-methyltetrahydrofolate in combined folate and B12 deficiency. Digestive Dis 1973;18(2):142-146.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2022-10-11T16:03:31+11:00","created_at":"2019-07-09T17:21:50+10:00","vendor":"BioCeuticals","type":"BioCeuticals Naturopathic Medicines","tags":["BioCeuticals","Methylation","MTHFR","Naturopathic","PB"],"price":2336,"price_min":2336,"price_max":2336,"available":true,"price_varies":false,"compare_at_price":2595,"compare_at_price_min":2595,"compare_at_price_max":2595,"compare_at_price_varies":false,"variants":[{"id":21199241347131,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"BiCMTHF60C","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"BioCeuticals MTHF 60 caps","public_title":null,"options":["Default Title"],"price":2336,"weight":50,"compare_at_price":2595,"inventory_quantity":19956,"inventory_management":"shopify","inventory_policy":"deny","barcode":"9337896001011","requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/bioceuticals-mthf-bmthf120_524x690_87befa28-ced2-4a84-a886-4b7bb6cb14ee.png?v=1603678773"],"featured_image":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/bioceuticals-mthf-bmthf120_524x690_87befa28-ced2-4a84-a886-4b7bb6cb14ee.png?v=1603678773","options":["Title"],"media":[{"alt":"BioCeuticals MTHF 60 caps 10% off RRP | HealthMasters BioCeuticals","id":2798241906747,"position":1,"preview_image":{"aspect_ratio":0.483,"height":1200,"width":579,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/bioceuticals-mthf-bmthf120_524x690_87befa28-ced2-4a84-a886-4b7bb6cb14ee.png?v=1603678773"},"aspect_ratio":0.483,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/bioceuticals-mthf-bmthf120_524x690_87befa28-ced2-4a84-a886-4b7bb6cb14ee.png?v=1603678773","width":579}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch3\u003e\u003cem\u003eBiologically Active Folate\u003c\/em\u003e\u003c\/h3\u003e\n\u003ch2\u003eBioCeuticals MTHF 60 caps\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBioCeuticals MTHF 5-methyltetrahydrofolate (5-MTHF) is the most active metabolite of folic acid, bypassing all of the enzymatic activation steps in the conversion of folic acid to the biologically active 5-MTHF.\u003c\/li\u003e\n\u003cli\u003eDirectly utilised by the body, 5-MTHF supports healthy methylation, homocysteine metabolism, DNA replication and foetal development.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eServing Type: Capsule\u003c\/p\u003e\n\u003cp\u003eAvailable In Sizes: 60 capsules\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBioCeuticals MTHF has No Added Dairy, No Added Gluten, No Added Shellfish, No Added Soy Protein, No Added Yeast.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBioCeuticals MTHF is Pregnancy Friendly, Vegan Friendly, Vegetarian Friendly.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eBioCeuticals MTHF conditions associated: Women's Health, Cognitive Health, Cardiovascular Health, Pregnancy Health, Nervous System\u003c\/p\u003e\n\u003cp\u003eBioCeuticals MTHF AUST L 260279\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioCeuticals MTHF\u003c\/h2\u003e\n\u003cp\u003eAdults: Take 1 capsule daily or as directed by your healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eFeatures\u003c\/h5\u003e\n\u003ch2\u003eFeatures: BioCeuticals MTHF\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eContains 5-MTHF, the most active form of folic acid.\u003c\/li\u003e\n\u003cli\u003eSupports a healthy brain and nervous system function.\u003c\/li\u003e\n\u003cli\u003eSupports healthy methylation pathways and homocysteine metabolism.\u003c\/li\u003e\n\u003cli\u003eIs involved in growth and cellular replication, and supports healthy replication of DNA through healthy DNA methylation.\u003c\/li\u003e\n\u003cli\u003eProvides 500mcg of 5-MTHF (active folate), which contributes to the normal growth of the foetus.\u003c\/li\u003e\n\u003cli\u003eIf taken daily for one month before conception and during pregnancy, may reduce the risk of women having a child with birth defects of the brain and\/or spinal cord such as the neural tube defects known as spina bifida and anencephaly.\u003c\/li\u003e\n\u003cli\u003eHelps maintain normal blood by helping to form red blood cells and assisting with their function.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioCeuticals MTHF\u003c\/h2\u003e\n\u003ctable width='100%\"'\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach capsule contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLevomefolate calcium\u003c\/td\u003e\n\u003ctd\u003e541.4mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. 5-MTHF (active folate)\u003c\/td\u003e\n\u003ctd\u003e500mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: BioCeuticals MTHF\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003e5-methyltetrahydrofolate (5-MTHF)\u003c\/em\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e5-MTHF is the active metabolite of folic acid. It does not require the enzymes dihydrofolate reductase (DHFR) or methylenetetrahydrofolate reductase (MTHFR) in order to participate in reactions utilising folates as a source of one-carbon moieties.\u003c\/li\u003e\n\u003cli\u003eFolic acid is converted to dihydrofolate (DHF) by DHF reductase (DHFR) and then tetrahydrofolate (THF). Folinic acid (5-formyl THF) is rapidly metabolised via 5,10-methylenetetrahydrofolate (5,10-MTHF), which is then converted to 5-methyltetrahydrofolate (5-MTHF). See Figure 1.\u003c\/li\u003e\n\u003cli\u003e5-MTHF can in turn be metabolised by other pathways back to 5,10-MTHF, which is converted to 5-MTHF by an irreversible enzyme MTHFR catalysed reduction using the cofactors FADH2 and NADPH.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: BioCeuticals MTHF\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eIf symptoms persist consult your healthcare practitioner.\u003c\/li\u003e\n\u003cli\u003eDo not exceed the stated dose except on medical advice.\u003c\/li\u003e\n\u003cli\u003eIf you have had a baby with neural tube defect\/spina bifida, seek medical advice.\u003c\/li\u003e\n\u003cli\u003eVitamin supplements should not replace a balanced diet.\u003c\/li\u003e\n\u003cli\u003eAlways read the label. Use only as directed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: BioCeuticals MTHF\u003c\/h2\u003e\n\u003cp\u003e[1] Fava M, Mischoulon D. Folate in depression: efficacy, safety, differences in formulation, and clinical issues. J Clin Psychiatry 2009;70(suppl 5):12-17.\u003c\/p\u003e\n\u003cp\u003e[2] Braun L, Cohen M. Herbs and natural supplements: an evidence-based guide, 3rd ed. Sydney: Churchill Livingstone Elsevier, 2010.\u003c\/p\u003e\n\u003cp\u003e[3] Folic acid\/5'-MTHF. Natural Medicines Comprehensive Database. Viewed 10 Nov 2015, www.naturaldatabase.com\u003c\/p\u003e\n\u003cp\u003e[4] 5-methyltetrahydrofolate monograph. AMR 2005;10(4):330-337.\u003c\/p\u003e\n\u003cp\u003e[5] Gutstein S, Bernstein LH, Levy L, et al. Failure of response to N5-methyltetrahydrofolate in combined folate and B12 deficiency. Digestive Dis 1973;18(2):142-146.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}