{"id":9296345675,"title":"Metagenics HPA Essentials 60 tablets","handle":"metagenics-hpa-essentials-60-tabs","description":"\u003ch3\u003e\u003cem\u003eFor Healthy Adrenal And Neuroendocrine Function\u003c\/em\u003e\u003c\/h3\u003e\n\u003ch2\u003eMetagenics HPA Essentials 60 tablets\u003c\/h2\u003e\n\u003cp\u003eSize: 60 tablets (30 days)\u003c\/p\u003e\n\u003cp\u003eMetagenics HPA Essentials has been shown to or may:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh dose vitamin B5 helps healthy neuroendocrine function in combination with Vitamin C for adrenal health.\u003c\/li\u003e\n\u003cli\u003eAssist metabolism and synthesis of some neurotransmitters.\u003c\/li\u003e\n\u003cli\u003eCore product in the Metagenics Stress Less Program and Energy Program.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMetagenics HPA Essentials is free from animal products, corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, soy protein and starches.\u003c\/p\u003e\n\u003cp\u003eMetagenics HPA Essentials is free from artificial colours, flavours and preservatives.\u003c\/p\u003e\n\u003cp\u003eMetagenics HPA Essentials AUST L 297273\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe products listed below are suggestions that may be used as a substitute if the product you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/metagenics-metagen-methyl-active-60caps\" target=\"_blank\" title=\"Metagenics Metagen Methyl-Active 10% off RRP | HealthMasters Metagenics\" rel=\"noopener\"\u003e\u003cspan style=\"text-decoration: underline;\"\u003eMetagenics Metagen Methyl-Active 60 VegeCaps\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/metagenics-meta-b-complex-50-tabs\" title=\"Metagenics Meta B Complex 10% off RRP | HealthMasters Metagenics\"\u003e\u003cspan style=\"text-decoration: underline;\"\u003eMetagenics Meta B Complex 50tabs\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate product, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca title=\"Contact HealthMasters For Assistance\" href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDescription\u003c\/h5\u003e\n\u003ch2\u003eDescription: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cp\u003eMetagenics HPA Essentials has been shown to or may:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh dose vitamin B5 helps healthy neuroendocrine function in combination with Vitamin C for adrenal health.\u003c\/li\u003e\n\u003cli\u003eAssist metabolism and synthesis of some neurotransmitters.\u003c\/li\u003e\n\u003cli\u003eCore product in the Metagenics Stress Less Program and Energy Program.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eActivated B vitamins:\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eLevomefolate calcium Equivalent Levomefolic acid (5-Methyltetrahydrofolate) (Vitamin B9)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePyridoxal 5-phosphate monohydrate (Vitamin B6)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMecobalamin (Co-methylcobalamin) (Vitamin B12)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eHelps protect from Hypothalamus-Pituitary-Adrenal dysfinction:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThiamine hydrocholoride (Vitamin B1)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMecobalamin (Co-methylcobalamin) (Vitamin B12)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eDecreased adrenal function:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eVitamin B5\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBiotin\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eProduct Video: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cstyle\u003e\u003c!--\n.embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; }\n--\u003e\u003c\/style\u003e\n\u003cdiv class=\"embed-container\"\u003e\u003ciframe src=\"https:\/\/player.vimeo.com\/video\/210539823\" frameborder=\"0\" webkitallowfullscreen=\"\" mozallowfullscreen=\"\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003ch5\u003eDirections\u003c\/h5\u003e\n\u003ch2\u003eDirections: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cp\u003eAdults:\u003c\/p\u003e\n\u003cp\u003eTake 1 tablet twice daily with food.\u003c\/p\u003e\n\u003ch5\u003eBenefits\u003c\/h5\u003e\n\u003ch2\u003eClinical Benefits: Metagenics HPA Essentials\u003cspan\u003e \u003c\/span\u003e\n\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImproves the adrenal gland rhythm.\u003csup\u003e4\u003c\/sup\u003e\u003c\/strong\u003e A researched trial of 52 people demonstrated a daily combination of vitamins B1 and B6, and 900 mg ascorbic acid, improved glucocorticoid function of the adrenal glands, and simultaneously normalised the rhythmic activity of the gland.\u003csup\u003e5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVitamins B1 and B12 help protect from HPA dysfunction and regulate the cortisol clock.\u003c\/strong\u003e Vitamin B1 has been shown to reduce cortisol activity in times of stress, thereby protecting the body against excessive cortisol.\u003csup\u003e8\u003c\/sup\u003e Although mecobalamin, the active form of vitamin B12, doesn’t increase levels of cortisol in the blood, evidence suggests it helps shift the cortisol secretion peak, helping place the cortisol clock back on schedule.\u003csup\u003e8\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eB vitamins needed for neurotransmitter synthesis.\u003c\/strong\u003e Vitamin B6 is important due to its function as a coenzyme in the biosynthesis of neurotransmitters GABA, noradrenaline, dopamine and serotonin.\u003csup\u003e6\u003c\/sup\u003e Pyridoxal 5-phosphate, (P5P), is the biologically active form of B6.\u003csup\u003e7\u003c\/sup\u003e Vitamin B5 is involved in the synthesis of melatonin from serotonin due to its progression to Coenzyme A (CoA), which donates its acetyl group to serotonin to convert to melatonin, which has been shown to have a favourable effect on certain dysphoric mental states such as restlessness, anxiety and depression.\u003csup\u003e6,8\u003c\/sup\u003e Vitamin B5 deficiency is specifically related to decreased adrenal function and biotin deficiency has been shown to contribute to adrenal insufficiency.\u003csup\u003e9\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003e\u003cstrong\u003eEach Metagenics HPA Essentials tablet contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eCalcium ascorbate dihydrate\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e545mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"padding-left: 30px; height: 16px;\"\u003eEquivalent Ascorbic acid (Vitamin C)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e450mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eCalcium pantothenate (Vitamin B5)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e300mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eCitrus bioflavonoids extract\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eThiamine hydrocholoride (Vitamin B1)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eNicotinamide (Vitamin B3)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003ePyridoxal 5-phosphate monohydrate (Vitamin B6)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eRiboflavin sodium phosphate (Vitamin B2)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e20mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eBiotin \u003cspan data-mce-fragment=\"1\"\u003e(Vitamin B7)\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e500µg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eLevomefolate calcium \u003cspan data-mce-fragment=\"1\"\u003e(Vitamin B9)\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e217µg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.6876px;\"\u003e\n\u003ctd style=\"padding-left: 30px; height: 17.6876px;\"\u003eEquivalent Levomefolic acid (5-Methyltetrahydrofolate)\u003c\/td\u003e\n\u003ctd style=\"height: 17.6876px;\"\u003e200µg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eMecobalamin (Co-methylcobalamin) (Vitamin B12)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e200µg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eMetagenics HPA Essentials is free from animal products, corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, soy protein and starches. Metagenics HPA Essentials is free from artificial colours, flavours and preservatives.\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cp\u003eWARNING: This product contains B6. See your healthcare professional if you experience tingling, burning or numbness.\u003c\/p\u003e\n\u003cp\u003eAlways read the label. Use only as directed. If symptoms persist consult your healthcare professional.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cp\u003eStore below 30° C\u003c\/p\u003e\n\u003ch5\u003eProduct Video\u003c\/h5\u003e\n\u003ch2\u003eProduct Video: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cstyle\u003e\u003c!--\n.embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; }\n--\u003e\u003c\/style\u003e\n\u003cdiv class=\"embed-container\"\u003e\u003ciframe src=\"https:\/\/player.vimeo.com\/video\/210539823\" frameborder=\"0\" webkitallowfullscreen=\"\" mozallowfullscreen=\"\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2022-10-11T14:14:32+11:00","created_at":"2017-06-29T17:41:11+10:00","vendor":"Metagenics","type":"Metagenics Naturopathic Medicines","tags":["Anxiety","Dairy protein free","Fatigue","Free from Nuts and Seeds","Free from Soy protein","Gluten free","Healthy Ageing","Insomnia","Lactose free","Melatonin","Metagenics","Methylation","MTHFR","Naturopathic","Nutrition","PB","Stress-Anxiety-Mood","Wellness"],"price":4496,"price_min":4496,"price_max":4496,"available":true,"price_varies":false,"compare_at_price":4995,"compare_at_price_min":4995,"compare_at_price_max":4995,"compare_at_price_varies":false,"variants":[{"id":33461911563,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"HPAEsstls60T","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Metagenics HPA Essentials 60 tablets","public_title":null,"options":["Default Title"],"price":4496,"weight":227,"compare_at_price":4995,"inventory_quantity":9668,"inventory_management":"shopify","inventory_policy":"continue","barcode":"9315771010204","requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-1.jpg?v=1621918205","\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-2.jpg?v=1621918236","\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-3.jpg?v=1593121122","\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/Metagenics_Products_10_off_RRP_at_HealthMasters_e3769937-0ef1-42d3-9763-e87d00ccf5c4.jpg?v=1593121093"],"featured_image":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-1.jpg?v=1621918205","options":["Title"],"media":[{"alt":"Metagenics HPA Essentials 60 Tabs 10% off RRP | HealthMasters Metagenics","id":9759475073182,"position":1,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-1.jpg?v=1621918205"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-1.jpg?v=1621918205","width":1200},{"alt":"Metagenics HPA Essentials 60 Tabs 10% off RRP | HealthMasters Metagenics Ingredients","id":9759475105950,"position":2,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-2.jpg?v=1621918236"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-2.jpg?v=1621918236","width":1200},{"alt":"Metagenics HPA Essentials 60 Tablets-3","id":9759475138718,"position":3,"preview_image":{"aspect_ratio":1.0,"height":2400,"width":2400,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-3.jpg?v=1593121122"},"aspect_ratio":1.0,"height":2400,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/MetagenicsHPAEssentials60Tablets-3.jpg?v=1593121122","width":2400},{"alt":"Metagenics HPA Essentials 60 tablets 10% off RRP | HealthMasters","id":2527477465147,"position":4,"preview_image":{"aspect_ratio":1.0,"height":1000,"width":1000,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/Metagenics_Products_10_off_RRP_at_HealthMasters_e3769937-0ef1-42d3-9763-e87d00ccf5c4.jpg?v=1593121093"},"aspect_ratio":1.0,"height":1000,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/Metagenics_Products_10_off_RRP_at_HealthMasters_e3769937-0ef1-42d3-9763-e87d00ccf5c4.jpg?v=1593121093","width":1000}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch3\u003e\u003cem\u003eFor Healthy Adrenal And Neuroendocrine Function\u003c\/em\u003e\u003c\/h3\u003e\n\u003ch2\u003eMetagenics HPA Essentials 60 tablets\u003c\/h2\u003e\n\u003cp\u003eSize: 60 tablets (30 days)\u003c\/p\u003e\n\u003cp\u003eMetagenics HPA Essentials has been shown to or may:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh dose vitamin B5 helps healthy neuroendocrine function in combination with Vitamin C for adrenal health.\u003c\/li\u003e\n\u003cli\u003eAssist metabolism and synthesis of some neurotransmitters.\u003c\/li\u003e\n\u003cli\u003eCore product in the Metagenics Stress Less Program and Energy Program.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMetagenics HPA Essentials is free from animal products, corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, soy protein and starches.\u003c\/p\u003e\n\u003cp\u003eMetagenics HPA Essentials is free from artificial colours, flavours and preservatives.\u003c\/p\u003e\n\u003cp\u003eMetagenics HPA Essentials AUST L 297273\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe products listed below are suggestions that may be used as a substitute if the product you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/metagenics-metagen-methyl-active-60caps\" target=\"_blank\" title=\"Metagenics Metagen Methyl-Active 10% off RRP | HealthMasters Metagenics\" rel=\"noopener\"\u003e\u003cspan style=\"text-decoration: underline;\"\u003eMetagenics Metagen Methyl-Active 60 VegeCaps\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/metagenics-meta-b-complex-50-tabs\" title=\"Metagenics Meta B Complex 10% off RRP | HealthMasters Metagenics\"\u003e\u003cspan style=\"text-decoration: underline;\"\u003eMetagenics Meta B Complex 50tabs\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate product, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca title=\"Contact HealthMasters For Assistance\" href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDescription\u003c\/h5\u003e\n\u003ch2\u003eDescription: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cp\u003eMetagenics HPA Essentials has been shown to or may:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh dose vitamin B5 helps healthy neuroendocrine function in combination with Vitamin C for adrenal health.\u003c\/li\u003e\n\u003cli\u003eAssist metabolism and synthesis of some neurotransmitters.\u003c\/li\u003e\n\u003cli\u003eCore product in the Metagenics Stress Less Program and Energy Program.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eActivated B vitamins:\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eLevomefolate calcium Equivalent Levomefolic acid (5-Methyltetrahydrofolate) (Vitamin B9)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePyridoxal 5-phosphate monohydrate (Vitamin B6)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMecobalamin (Co-methylcobalamin) (Vitamin B12)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eHelps protect from Hypothalamus-Pituitary-Adrenal dysfinction:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eThiamine hydrocholoride (Vitamin B1)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMecobalamin (Co-methylcobalamin) (Vitamin B12)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eDecreased adrenal function:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eVitamin B5\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBiotin\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eProduct Video: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cstyle\u003e\u003c!--\n.embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; }\n--\u003e\u003c\/style\u003e\n\u003cdiv class=\"embed-container\"\u003e\u003ciframe src=\"https:\/\/player.vimeo.com\/video\/210539823\" frameborder=\"0\" webkitallowfullscreen=\"\" mozallowfullscreen=\"\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003ch5\u003eDirections\u003c\/h5\u003e\n\u003ch2\u003eDirections: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cp\u003eAdults:\u003c\/p\u003e\n\u003cp\u003eTake 1 tablet twice daily with food.\u003c\/p\u003e\n\u003ch5\u003eBenefits\u003c\/h5\u003e\n\u003ch2\u003eClinical Benefits: Metagenics HPA Essentials\u003cspan\u003e \u003c\/span\u003e\n\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImproves the adrenal gland rhythm.\u003csup\u003e4\u003c\/sup\u003e\u003c\/strong\u003e A researched trial of 52 people demonstrated a daily combination of vitamins B1 and B6, and 900 mg ascorbic acid, improved glucocorticoid function of the adrenal glands, and simultaneously normalised the rhythmic activity of the gland.\u003csup\u003e5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVitamins B1 and B12 help protect from HPA dysfunction and regulate the cortisol clock.\u003c\/strong\u003e Vitamin B1 has been shown to reduce cortisol activity in times of stress, thereby protecting the body against excessive cortisol.\u003csup\u003e8\u003c\/sup\u003e Although mecobalamin, the active form of vitamin B12, doesn’t increase levels of cortisol in the blood, evidence suggests it helps shift the cortisol secretion peak, helping place the cortisol clock back on schedule.\u003csup\u003e8\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eB vitamins needed for neurotransmitter synthesis.\u003c\/strong\u003e Vitamin B6 is important due to its function as a coenzyme in the biosynthesis of neurotransmitters GABA, noradrenaline, dopamine and serotonin.\u003csup\u003e6\u003c\/sup\u003e Pyridoxal 5-phosphate, (P5P), is the biologically active form of B6.\u003csup\u003e7\u003c\/sup\u003e Vitamin B5 is involved in the synthesis of melatonin from serotonin due to its progression to Coenzyme A (CoA), which donates its acetyl group to serotonin to convert to melatonin, which has been shown to have a favourable effect on certain dysphoric mental states such as restlessness, anxiety and depression.\u003csup\u003e6,8\u003c\/sup\u003e Vitamin B5 deficiency is specifically related to decreased adrenal function and biotin deficiency has been shown to contribute to adrenal insufficiency.\u003csup\u003e9\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003e\u003cstrong\u003eEach Metagenics HPA Essentials tablet contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eCalcium ascorbate dihydrate\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e545mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"padding-left: 30px; height: 16px;\"\u003eEquivalent Ascorbic acid (Vitamin C)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e450mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eCalcium pantothenate (Vitamin B5)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e300mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eCitrus bioflavonoids extract\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eThiamine hydrocholoride (Vitamin B1)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eNicotinamide (Vitamin B3)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003ePyridoxal 5-phosphate monohydrate (Vitamin B6)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eRiboflavin sodium phosphate (Vitamin B2)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e20mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eBiotin \u003cspan data-mce-fragment=\"1\"\u003e(Vitamin B7)\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e500µg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eLevomefolate calcium \u003cspan data-mce-fragment=\"1\"\u003e(Vitamin B9)\u003c\/span\u003e\n\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e217µg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.6876px;\"\u003e\n\u003ctd style=\"padding-left: 30px; height: 17.6876px;\"\u003eEquivalent Levomefolic acid (5-Methyltetrahydrofolate)\u003c\/td\u003e\n\u003ctd style=\"height: 17.6876px;\"\u003e200µg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd style=\"height: 16px;\"\u003eMecobalamin (Co-methylcobalamin) (Vitamin B12)\u003c\/td\u003e\n\u003ctd style=\"height: 16px;\"\u003e200µg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003eMetagenics HPA Essentials is free from animal products, corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, soy protein and starches. Metagenics HPA Essentials is free from artificial colours, flavours and preservatives.\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cp\u003eWARNING: This product contains B6. See your healthcare professional if you experience tingling, burning or numbness.\u003c\/p\u003e\n\u003cp\u003eAlways read the label. Use only as directed. If symptoms persist consult your healthcare professional.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cp\u003eStore below 30° C\u003c\/p\u003e\n\u003ch5\u003eProduct Video\u003c\/h5\u003e\n\u003ch2\u003eProduct Video: Metagenics HPA Essentials\u003c\/h2\u003e\n\u003cstyle\u003e\u003c!--\n.embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; }\n--\u003e\u003c\/style\u003e\n\u003cdiv class=\"embed-container\"\u003e\u003ciframe src=\"https:\/\/player.vimeo.com\/video\/210539823\" frameborder=\"0\" webkitallowfullscreen=\"\" mozallowfullscreen=\"\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003c!-- \/TABS --\u003e"}