Metagenics TocoCare 30 capsules
Directions: Metagenics TocoCare
Adults: Take 1 capsule at night.
Clinical Benefits: Metagenics TocoCare
- The combination of 270 mg of citrus bioflavonoids and 18 mg of tocotrienols, has been shown to impact total cholesterol by an average of 25% over 4 weeks and 27% over 12 weeks1: Three studies including a double blind, randomised clinical trial plus two open-label trials demonstrated significant reductions in total cholesterol, triglycerides and LDL:HDL ratio (Figure One).1
Figure One: Citrus Bioflavonoids and Tocotrienol Combination Impact Cholesterol in a Clinical Trial with 120 subjects.
- Key mechanisms include HMG-CoA reductase inhibition, reduction of apolipoprotein-B100 secretion and modulation of hepatic LDL receptors.2,3 Specifically, the polymethoxyflavones tangeretin and nobiletin, suppress the hepatic secretion of ApoB and increase LDL receptor synthesis.4,2 is an exclusive extract of citrus bioflavonoids containing at least 11.5 mg of tangeretin and 10 mg nobiletin per dose.
- Tocotrienols inhibit the production of HMGCoA reductase but support endogenous CoQ10 production via induction of the enzyme geranylgeranyl pyrophosphate (GGPP)2. In vitro research shows an 80% inhibition of HMG-CoA reductase by decreasing transcription efficiency and enhancing degradation, unlike most HMG-CoA reductase inhibitors which block the mevalonate pathway by up to 99%.5
Figure Two: Ingredients in CholCare act upon multiple points within the Mevalonate Pathway.
Ingredients: Metagenics TocoCare
Each capsule contains: |
|
Citrus bioflavonoids extract |
270 mg |
Tocotrienols complex - palm* |
18 mg |
Metagenics TocoCare is free from corn, dairy protein, lactose, eggs, gluten, wheat, nuts, soy protein, starches and salt. Metagenics TocoCare is free from artificial colours, flavours and preservatives.
Warnings
*Sustainably sourced palm.
Not all cautions and contraindications are listed. For full details, references or more information contact HealthMasters in Australia on 02 4369 7770 or email reception@healthmasters.com.au.
Always read the label. Use only as directed. If symptoms persist consult your healthcare professional.
Storage
Store below 30° C