{"id":2288394010683,"title":"BioCeuticals D3 + K2 Spray 50mL liquid","handle":"bioceuticals-d3-k2-spray-50ml-liquid","description":"\u003ch3\u003e\u003cem\u003eSupporting bone and cardiovascular systems\u003c\/em\u003e\u003c\/h3\u003e\n\u003ch2\u003eBioCeuticals D3 + K2 Spray 50mL liquid\u003c\/h2\u003e\n\u003cp\u003eSizes: 50ml (277 sprays)\u003c\/p\u003e\n\u003cp\u003eBioCeuticals D3 + K2 Spray helps with:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVitamin D and vitamin K2 are important for supporting bone health.\u003c\/li\u003e\n\u003cli\u003eVitamin D helps maintain bone mineralisation and bone strength as well as assists in healthy bone development.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eVitamin D also supports healthy immune system and nervous system function.\u003c\/li\u003e\n\u003cli\u003eVitamin K supports artery health and maintains healthy cardiovascular system function.\u003c\/li\u003e\n\u003cli\u003eVitamin K maintains teeth mineralisation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBioCeuticals D3 + K2 Spray AUST L 227245\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe products listed below are suggestions that may be used as a substitute if the product you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca title=\"Vitamin D3 Products10% off RRP | HealthMasters Vitamin D3\" href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/vitamin-d3\" target=\"_blank\"\u003e \u003cspan style=\"text-decoration: underline;\"\u003eVitamin D3 Products\u003c\/span\u003e\u003c\/a\u003e (Regular Vitamin D3 - \u003cspan\u003eCholecalciferol\u003c\/span\u003e)\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/calcifediol\" title=\"Active Vitamin D Products | HealthMasters Active Vitamin D\" target=\"_blank\"\u003e \u003cspan style=\"text-decoration: underline;\"\u003eActive Vitamin D Products\u003c\/span\u003e\u003c\/a\u003e (Calcifediol)\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate product, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\"\u003e\u003ca title=\"Contact HealthMasters For Assistance\" href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cp\u003eAdults: Pump 1 spray (180 microlitres) into the mouth once a day, or as professionally prescribed.\u003c\/p\u003e\n\u003cp\u003eShake well before use.\u003c\/p\u003e\n\u003cp\u003eEach 50 mL bottle contains 277 sprays.\u003c\/p\u003e\n\u003ch5\u003eFeatures\u003c\/h5\u003e\n\u003ch2\u003eFeatures: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVitamin D supports the absorption of dietary calcium.\u003c\/li\u003e\n\u003cli\u003eD3 + K2 spray supports vitamin D and K levels in the body.\u003c\/li\u003e\n\u003cli\u003eVitamin D helps to maintain healthy immune system function.\u003c\/li\u003e\n\u003cli\u003eVitamin D aids in healthy bone development and supports bone mineralisation and bone strength in ageing individuals.\u003c\/li\u003e\n\u003cli\u003eVitamins D and K support bone health.\u003c\/li\u003e\n\u003cli\u003eVitamins D and K support healthy cardiovascular system function.\u003c\/li\u003e\n\u003cli\u003eVitamin K supports artery health.\u003c\/li\u003e\n\u003cli\u003eVitamin D supports nervous system function.\u003c\/li\u003e\n\u003cli\u003eVitamin K maintains teeth mineralisation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eD3 + K2: the body’s bone and cardiovascular partners\u003c\/h3\u003e\n\u003cp\u003eOVER 90% of studies showed benefits of using  vitamins D and K together for bone health and cardiovascular function, in a systematic review8.\u003c\/p\u003e\n\u003ch3\u003eD3 + K2 Spray for adults who:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHave low vitamin D and K levels1,2\u003c\/li\u003e\n\u003cli\u003eHave diets lacking in vitamins D3 and K2 rich foods2,3\u003c\/li\u003e\n\u003cli\u003eNeed bone strengthening and  mineralisation support\u003c\/li\u003e\n\u003cli\u003eWant to support their artery health and cardiovascular function2,5\u003c\/li\u003e\n\u003cli\u003eAre in their later years, including post-menopausal women and men over 506,7\u003c\/li\u003e\n\u003cli\u003eLive an indoor or low sun exposure lifestyle6\u003c\/li\u003e\n\u003cli\u003eWant immune and nervous system support6\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003ctable width='100%\"'\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach 180mcL dose (1 spray) contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCholecalciferol\u003c\/td\u003e\n\u003ctd\u003e25mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. vitamin D3\u003c\/td\u003e\n\u003ctd\u003e1000IU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMenaquinone 7 (vitamin K2)\u003c\/td\u003e\n\u003ctd\u003e45micrograms\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eDietary influence\u003c\/h5\u003e\n\u003ch2\u003eDietary influence: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cp\u003eNo Added Dairy, Halal Certified, No Added Gluten, No Added Yeast\u003c\/p\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cp\u003eVitamin D3 and vitamin K2 are fat-soluble vitamins that work together in the healthy functioning of major body systems, including the skeletal and cardiovascular systems.2,4,5\u003c\/p\u003e\n\u003ch3\u003eVitamin D3\u003c\/h3\u003e\n\u003cp\u003eD3 is the main form in humans and is produced in the skin through contact with the sun, with diet and supplements as secondary sources.4,5 However, vitamin D deficiency is a global concern, even in sunny Australia.1,5\u003c\/p\u003e\n\u003ch3\u003eVitamin K2 (MK-7)\u003c\/h3\u003e\n\u003cp\u003eVitamin K is available in different forms – phylloquinone (K1) and various menaquinones (K2). Menaquinones are named based on their structure, which also affects their efficacy and absorption efficiency. Menaquinone 7 (K2-7 or MK-7) is naturally occurring with researched health benefits and superior absorption and bioavailability to other vitamin K forms. It also has a 72-hour half-life compared to 1 hour with K2-4 (MK-4).2,9\u003c\/p\u003e\n\u003ch3\u003eVitamin D3 in bone and cardiovascular function\u003c\/h3\u003e\n\u003cp\u003eVitamin D3, as its biologically active form calcitriol, is involved in every step of calcium regulation and is essential for bone health, strength and density. When serum calcium levels drop parathyroid hormone (PTH) is released, which triggers calcitriol production. Calcitriol interacts with vitamin D receptors (VDRs) to increase dietary calcium absorption, and along with PTH, increases circulating calcium plasma levels when they are low, which is necessary for ongoing bone mineralisation.6,10 In the cardiovascular system, vitamin D plays numerous roles, including endothelial function and vascular contraction. However, calcium regulation is again important by helping to reduce platelet aggregation.5\u003c\/p\u003e\n\u003ch3\u003eVitamin K2 (MK-7) supports bone and artery health\u003c\/h3\u003e\n\u003cp\u003eVitamin K2, as MK-7, reduces circulating calcium being deposited within artery walls, thereby supporting artery health, and is necessary for calcium transport to the bone.2 MK-7 is an essential cofactor in the activation of the vitamin K-dependent proteins (VKDPs), matrix Gla protein (MGP) and osteocalcin. It is required for the carboxylation and phosphorylation (activation) of MGP, which in turn reduces calcium deposition on artery walls. Osteocalcin is produced by the bone building cells (osteoblasts) but is also inactive until it is carboxylated by MK-7. Once activated it binds and transports circulating plasma calcium to the bone matrix.2\u003c\/p\u003e\n\u003ch5\u003eWarning\u003c\/h5\u003e\n\u003ch2\u003eWarning: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cp\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/p\u003e\n\u003cp\u003eAlways read the label and follow the directions for use.\u003c\/p\u003e\n\u003cp\u003eIf you are pregnant or breastfeeding, talk to your health professional before use.\u003c\/p\u003e\n\u003cp\u003eDietary supplements can only be of assistance if dietary intake is inadequate.\u003c\/p\u003e\n\u003cp\u003eIf you have any pre-existing conditions, are on any medications, always talk to your health professional before use.\u003c\/p\u003e\n\u003cp\u003eSome products should be ceased at least two weeks before any elective surgery, please confirm with your health professional.\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eDunlop E, Boorman JL, Hambridge TL, et al. Evidence of low vitamin D intakes in the Australian population points to a need for data-driven nutrition policy for improving population vitamin D status. J Hum Nutr Diet. 2023;36(1):203–15.\u003c\/li\u003e\n\u003cli\u003eJadhav N, Ajgaonkar S, Saha P, et al. Molecular pathways and roles for vitamin K2-7 as a health-beneficial nutraceutical: challenges and opportunities. Front Pharmacol. 2022;13:896920.\u003c\/li\u003e\n\u003cli\u003eBopape PG, Wagenaar C, Poka M, et al. Vitamin D supplementation in a post-pandemic era: A narrative review. South African Family Practice. 2023;65(4):a5752.\u003c\/li\u003e\n\u003cli\u003eDědečková E, Viták R, Jirásko M, et al. Vitamin D3 supplementation: comparison of 1000 IU and 2000 IU dose in healthy individuals. Life (Basel). 2023;13(3):808.\u003c\/li\u003e\n\u003cli\u003eNardin M, Verdoia M, Nardin S, et al. Vitamin D and cardiovascular diseases: from physiology to pathophysiology and outcomes. Biomedicines. 2024;12(4):768.\u003c\/li\u003e\n\u003cli\u003eHigdon J. Linus Pauling Institute, Oregon State University. Vitamin D. Viewed May 20 2024, https:\/\/lpi.oregonstate.edu\/mic\/vitamins\/vitamin-D\u003c\/li\u003e\n\u003cli\u003eNPS MedicineWise. 2019. Vitamin D supplementation in musculoskeletal health: what’s new? Viewed 16 July 2024,ww https:\/\/www.nps.org.au\/news\/vitamin-d-supplementation\u003c\/li\u003e\n\u003cli\u003eSingh V, Jain S, Prakash S, et al. Studies on the synergistic interplay of vitamin D and K for improving bone and cardiovascular health. Current Research in Nutrition and Food Science Journal. 2022;10(3):840–57.\u003c\/li\u003e\n\u003cli\u003eZhang T, O’Connor C, Sheridan H, Barlow JW. Vitamin K2 in health and disease: a clinical perspective. Foods. 2024;13(11):1646. 10.\u003c\/li\u003e\n\u003cli\u003eVeldurthy V, Wei R, Oz L, et al. Vitamin D, calcium homeostasis and aging. Bone Res. 2016;4:16041. 11.\u003c\/li\u003e\n\u003cli\u003eTakahashi N, Udagawa N, Suda T. Vitamin D endocrine system and osteoclasts. Bonekey Rep. 2014;3:495.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2022-10-11T14:05:38+11:00","created_at":"2019-07-09T17:20:36+10:00","vendor":"BioCeuticals","type":"BioCeuticals Naturopathic Medicines","tags":["BioCeuticals","Naturopathic","PB","Vitamin D3"],"price":4676,"price_min":4676,"price_max":4676,"available":true,"price_varies":false,"compare_at_price":5195,"compare_at_price_min":5195,"compare_at_price_max":5195,"compare_at_price_varies":false,"variants":[{"id":21199235579963,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"D3K2Spray50mLoralliquid","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"BioCeuticals D3 + K2 Spray 50mL liquid","public_title":null,"options":["Default Title"],"price":4676,"weight":70,"compare_at_price":5195,"inventory_quantity":19938,"inventory_management":"shopify","inventory_policy":"deny","barcode":"9337896000601","requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticals.jpg?v=1736922268","\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsIngredients.png?v=1736922004","\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsDirections.png?v=1736922004","\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsCardiovascular.png?v=1736922004","\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsBones.png?v=1736922004","\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsAdultDose.png?v=1736922004","\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsArteries.png?v=1736922004","\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsPractitionerOnly.png?v=1736922004","\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsInnovation.png?v=1736922004"],"featured_image":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticals.jpg?v=1736922268","options":["Title"],"media":[{"alt":"BioCeuticals D3 + K2 Spray 50mL 10% off RRP at HealthMasters BioCeuticals","id":35315702726886,"position":1,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticals.jpg?v=1736922268"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticals.jpg?v=1736922268","width":1200},{"alt":"BioCeuticals D3 + K2 Spray 50mL 10% off RRP at HealthMasters BioCeuticals Ingredients","id":35315497337062,"position":2,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsIngredients.png?v=1736922004"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsIngredients.png?v=1736922004","width":1200},{"alt":"BioCeuticals D3 + K2 Spray 50mL 10% off RRP at HealthMasters BioCeuticals Directions","id":35315497238758,"position":3,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsDirections.png?v=1736922004"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsDirections.png?v=1736922004","width":1200},{"alt":"BioCeuticals D3 + K2 Spray 50mL 10% off RRP at HealthMasters BioCeuticals Cardiovascular","id":35315497205990,"position":4,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsCardiovascular.png?v=1736922004"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsCardiovascular.png?v=1736922004","width":1200},{"alt":"BioCeuticals D3 + K2 Spray 50mL 10% off RRP at HealthMasters BioCeuticals Bones","id":35315497140454,"position":5,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsBones.png?v=1736922004"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsBones.png?v=1736922004","width":1200},{"alt":"BioCeuticals D3 + K2 Spray 50mL 10% off RRP at HealthMasters BioCeuticals Adult Dose","id":35315497173222,"position":6,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsAdultDose.png?v=1736922004"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsAdultDose.png?v=1736922004","width":1200},{"alt":"BioCeuticals D3 + K2 Spray 50mL 10% off RRP at HealthMasters BioCeuticals Arteries","id":35315497107686,"position":7,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsArteries.png?v=1736922004"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsArteries.png?v=1736922004","width":1200},{"alt":"BioCeuticals D3 + K2 Spray 50mL 10% off RRP at HealthMasters BioCeuticals Practitioner Only","id":35315497042150,"position":8,"preview_image":{"aspect_ratio":1.0,"height":1536,"width":1536,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsPractitionerOnly.png?v=1736922004"},"aspect_ratio":1.0,"height":1536,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsPractitionerOnly.png?v=1736922004","width":1536},{"alt":"BioCeuticals D3 + K2 Spray 50mL 10% off RRP at HealthMasters BioCeuticals Innovation","id":35315497074918,"position":9,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsInnovation.png?v=1736922004"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioCeuticalsD3_K2Spray50mL10_offRRPatHealthMastersBioCeuticalsInnovation.png?v=1736922004","width":1200}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch3\u003e\u003cem\u003eSupporting bone and cardiovascular systems\u003c\/em\u003e\u003c\/h3\u003e\n\u003ch2\u003eBioCeuticals D3 + K2 Spray 50mL liquid\u003c\/h2\u003e\n\u003cp\u003eSizes: 50ml (277 sprays)\u003c\/p\u003e\n\u003cp\u003eBioCeuticals D3 + K2 Spray helps with:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVitamin D and vitamin K2 are important for supporting bone health.\u003c\/li\u003e\n\u003cli\u003eVitamin D helps maintain bone mineralisation and bone strength as well as assists in healthy bone development.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eVitamin D also supports healthy immune system and nervous system function.\u003c\/li\u003e\n\u003cli\u003eVitamin K supports artery health and maintains healthy cardiovascular system function.\u003c\/li\u003e\n\u003cli\u003eVitamin K maintains teeth mineralisation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBioCeuticals D3 + K2 Spray AUST L 227245\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe products listed below are suggestions that may be used as a substitute if the product you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca title=\"Vitamin D3 Products10% off RRP | HealthMasters Vitamin D3\" href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/vitamin-d3\" target=\"_blank\"\u003e \u003cspan style=\"text-decoration: underline;\"\u003eVitamin D3 Products\u003c\/span\u003e\u003c\/a\u003e (Regular Vitamin D3 - \u003cspan\u003eCholecalciferol\u003c\/span\u003e)\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/calcifediol\" title=\"Active Vitamin D Products | HealthMasters Active Vitamin D\" target=\"_blank\"\u003e \u003cspan style=\"text-decoration: underline;\"\u003eActive Vitamin D Products\u003c\/span\u003e\u003c\/a\u003e (Calcifediol)\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate product, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\"\u003e\u003ca title=\"Contact HealthMasters For Assistance\" href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cp\u003eAdults: Pump 1 spray (180 microlitres) into the mouth once a day, or as professionally prescribed.\u003c\/p\u003e\n\u003cp\u003eShake well before use.\u003c\/p\u003e\n\u003cp\u003eEach 50 mL bottle contains 277 sprays.\u003c\/p\u003e\n\u003ch5\u003eFeatures\u003c\/h5\u003e\n\u003ch2\u003eFeatures: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVitamin D supports the absorption of dietary calcium.\u003c\/li\u003e\n\u003cli\u003eD3 + K2 spray supports vitamin D and K levels in the body.\u003c\/li\u003e\n\u003cli\u003eVitamin D helps to maintain healthy immune system function.\u003c\/li\u003e\n\u003cli\u003eVitamin D aids in healthy bone development and supports bone mineralisation and bone strength in ageing individuals.\u003c\/li\u003e\n\u003cli\u003eVitamins D and K support bone health.\u003c\/li\u003e\n\u003cli\u003eVitamins D and K support healthy cardiovascular system function.\u003c\/li\u003e\n\u003cli\u003eVitamin K supports artery health.\u003c\/li\u003e\n\u003cli\u003eVitamin D supports nervous system function.\u003c\/li\u003e\n\u003cli\u003eVitamin K maintains teeth mineralisation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eD3 + K2: the body’s bone and cardiovascular partners\u003c\/h3\u003e\n\u003cp\u003eOVER 90% of studies showed benefits of using  vitamins D and K together for bone health and cardiovascular function, in a systematic review8.\u003c\/p\u003e\n\u003ch3\u003eD3 + K2 Spray for adults who:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHave low vitamin D and K levels1,2\u003c\/li\u003e\n\u003cli\u003eHave diets lacking in vitamins D3 and K2 rich foods2,3\u003c\/li\u003e\n\u003cli\u003eNeed bone strengthening and  mineralisation support\u003c\/li\u003e\n\u003cli\u003eWant to support their artery health and cardiovascular function2,5\u003c\/li\u003e\n\u003cli\u003eAre in their later years, including post-menopausal women and men over 506,7\u003c\/li\u003e\n\u003cli\u003eLive an indoor or low sun exposure lifestyle6\u003c\/li\u003e\n\u003cli\u003eWant immune and nervous system support6\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003ctable width='100%\"'\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach 180mcL dose (1 spray) contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCholecalciferol\u003c\/td\u003e\n\u003ctd\u003e25mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. vitamin D3\u003c\/td\u003e\n\u003ctd\u003e1000IU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMenaquinone 7 (vitamin K2)\u003c\/td\u003e\n\u003ctd\u003e45micrograms\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eDietary influence\u003c\/h5\u003e\n\u003ch2\u003eDietary influence: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cp\u003eNo Added Dairy, Halal Certified, No Added Gluten, No Added Yeast\u003c\/p\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cp\u003eVitamin D3 and vitamin K2 are fat-soluble vitamins that work together in the healthy functioning of major body systems, including the skeletal and cardiovascular systems.2,4,5\u003c\/p\u003e\n\u003ch3\u003eVitamin D3\u003c\/h3\u003e\n\u003cp\u003eD3 is the main form in humans and is produced in the skin through contact with the sun, with diet and supplements as secondary sources.4,5 However, vitamin D deficiency is a global concern, even in sunny Australia.1,5\u003c\/p\u003e\n\u003ch3\u003eVitamin K2 (MK-7)\u003c\/h3\u003e\n\u003cp\u003eVitamin K is available in different forms – phylloquinone (K1) and various menaquinones (K2). Menaquinones are named based on their structure, which also affects their efficacy and absorption efficiency. Menaquinone 7 (K2-7 or MK-7) is naturally occurring with researched health benefits and superior absorption and bioavailability to other vitamin K forms. It also has a 72-hour half-life compared to 1 hour with K2-4 (MK-4).2,9\u003c\/p\u003e\n\u003ch3\u003eVitamin D3 in bone and cardiovascular function\u003c\/h3\u003e\n\u003cp\u003eVitamin D3, as its biologically active form calcitriol, is involved in every step of calcium regulation and is essential for bone health, strength and density. When serum calcium levels drop parathyroid hormone (PTH) is released, which triggers calcitriol production. Calcitriol interacts with vitamin D receptors (VDRs) to increase dietary calcium absorption, and along with PTH, increases circulating calcium plasma levels when they are low, which is necessary for ongoing bone mineralisation.6,10 In the cardiovascular system, vitamin D plays numerous roles, including endothelial function and vascular contraction. However, calcium regulation is again important by helping to reduce platelet aggregation.5\u003c\/p\u003e\n\u003ch3\u003eVitamin K2 (MK-7) supports bone and artery health\u003c\/h3\u003e\n\u003cp\u003eVitamin K2, as MK-7, reduces circulating calcium being deposited within artery walls, thereby supporting artery health, and is necessary for calcium transport to the bone.2 MK-7 is an essential cofactor in the activation of the vitamin K-dependent proteins (VKDPs), matrix Gla protein (MGP) and osteocalcin. It is required for the carboxylation and phosphorylation (activation) of MGP, which in turn reduces calcium deposition on artery walls. Osteocalcin is produced by the bone building cells (osteoblasts) but is also inactive until it is carboxylated by MK-7. Once activated it binds and transports circulating plasma calcium to the bone matrix.2\u003c\/p\u003e\n\u003ch5\u003eWarning\u003c\/h5\u003e\n\u003ch2\u003eWarning: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003cp\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/p\u003e\n\u003cp\u003eAlways read the label and follow the directions for use.\u003c\/p\u003e\n\u003cp\u003eIf you are pregnant or breastfeeding, talk to your health professional before use.\u003c\/p\u003e\n\u003cp\u003eDietary supplements can only be of assistance if dietary intake is inadequate.\u003c\/p\u003e\n\u003cp\u003eIf you have any pre-existing conditions, are on any medications, always talk to your health professional before use.\u003c\/p\u003e\n\u003cp\u003eSome products should be ceased at least two weeks before any elective surgery, please confirm with your health professional.\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: BioCeuticals D3 + K2 Spray\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eDunlop E, Boorman JL, Hambridge TL, et al. Evidence of low vitamin D intakes in the Australian population points to a need for data-driven nutrition policy for improving population vitamin D status. J Hum Nutr Diet. 2023;36(1):203–15.\u003c\/li\u003e\n\u003cli\u003eJadhav N, Ajgaonkar S, Saha P, et al. Molecular pathways and roles for vitamin K2-7 as a health-beneficial nutraceutical: challenges and opportunities. Front Pharmacol. 2022;13:896920.\u003c\/li\u003e\n\u003cli\u003eBopape PG, Wagenaar C, Poka M, et al. Vitamin D supplementation in a post-pandemic era: A narrative review. South African Family Practice. 2023;65(4):a5752.\u003c\/li\u003e\n\u003cli\u003eDědečková E, Viták R, Jirásko M, et al. Vitamin D3 supplementation: comparison of 1000 IU and 2000 IU dose in healthy individuals. Life (Basel). 2023;13(3):808.\u003c\/li\u003e\n\u003cli\u003eNardin M, Verdoia M, Nardin S, et al. Vitamin D and cardiovascular diseases: from physiology to pathophysiology and outcomes. Biomedicines. 2024;12(4):768.\u003c\/li\u003e\n\u003cli\u003eHigdon J. Linus Pauling Institute, Oregon State University. Vitamin D. Viewed May 20 2024, https:\/\/lpi.oregonstate.edu\/mic\/vitamins\/vitamin-D\u003c\/li\u003e\n\u003cli\u003eNPS MedicineWise. 2019. Vitamin D supplementation in musculoskeletal health: what’s new? Viewed 16 July 2024,ww https:\/\/www.nps.org.au\/news\/vitamin-d-supplementation\u003c\/li\u003e\n\u003cli\u003eSingh V, Jain S, Prakash S, et al. Studies on the synergistic interplay of vitamin D and K for improving bone and cardiovascular health. Current Research in Nutrition and Food Science Journal. 2022;10(3):840–57.\u003c\/li\u003e\n\u003cli\u003eZhang T, O’Connor C, Sheridan H, Barlow JW. Vitamin K2 in health and disease: a clinical perspective. Foods. 2024;13(11):1646. 10.\u003c\/li\u003e\n\u003cli\u003eVeldurthy V, Wei R, Oz L, et al. Vitamin D, calcium homeostasis and aging. Bone Res. 2016;4:16041. 11.\u003c\/li\u003e\n\u003cli\u003eTakahashi N, Udagawa N, Suda T. Vitamin D endocrine system and osteoclasts. Bonekey Rep. 2014;3:495.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c!-- \/TABS --\u003e"}