{"id":8367861530854,"title":"Activated Probiotics Biome Advanced Probiotic","handle":"activated-probiotics-biome-advanced-probiotic","description":"\u003ch2\u003eActivated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eTo help restore beneficial gut bacteria after antibiotic use\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003ePack Size: 10 VegCaps and 30 VegCaps\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eActivated Probiotics Biome Advanced Probiotic Summary:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHelps restore beneficial gut bacteria after antibiotic use.\u003c\/li\u003e\n\u003cli\u003eMicrobac technology: 5x more effective delivery.\u003c\/li\u003e\n\u003cli\u003eGuaranteed potency.\u003c\/li\u003e\n\u003cli\u003eClinically trialed probiotic strains.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eActivated Probiotics formulate premium probiotic products backed by cutting-edge scientific research on the human gut microbiome. Using targeted bacterial strains at doses supported by clinical trials, Activated Probiotics seeks to provide tangible improvements in health and well-being with a new generation of evidence-based probiotics.\u003c\/p\u003e\n\u003cp\u003eActivated Probiotics Biome Advanced Probiotic has No Added: GMOs, wheat, gluten, dairy, lactose, fructose, yeast, nuts, seeds, peanut, soy, egg, fish, shellfish, or animal derivatives.\u003c\/p\u003e\n\u003cp\u003eNo artificial colours, flavours, sweeteners, or preservatives.\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp\u003eSuitable for vegetarians and vegans.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eActivated Probiotics Biome Advanced Probiotic AUST L 315959\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eAilments\u003c\/h5\u003e\n\u003ch2\u003eAilments: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports beneficial gut bacteria during antibiotic use\u003c\/li\u003e\n\u003cli\u003eHelps restore beneficial gut bacteria after antibiotic use\u003c\/li\u003e\n\u003cli\u003ePromotes healthy digestion and bowel regularity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eInstructions For Use\u003c\/h5\u003e\n\u003ch2\u003eInstructions For Use: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003eAdults and children over 12 years:\u003c\/p\u003e\n\u003cp\u003etake 1 capsule daily (with or without food), or as directed by your healthcare practitioner.\u003c\/p\u003e\n\u003cp\u003eActivated Probiotics Biome Advanced Probiotic is recommended daily during antibiotic use, starting on the first day of the course. Continue taking Activated Probiotics Biome Advanced Probiotic daily for at least two weeks after completing the course of antibiotics.\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach VegCap Contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus plantarum (DSM6595)\u003c\/td\u003e\n\u003ctd\u003e9 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus plantarum (HEAL 9-DSM 15312)\u003c\/td\u003e\n\u003ctd\u003e0.5 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus paracasei (8700:2-DSM 13434)\u003c\/td\u003e\n\u003ctd\u003e0.5 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus rhamnosus (ATCC 53103)\u003c\/td\u003e\n\u003ctd\u003e5 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus acidophilus (LA02-DSM 21717)\u003c\/td\u003e\n\u003ctd\u003e5 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBifidobacterium animalis ssp. lactis (BS01-LMG P-21384)\u003c\/td\u003e\n\u003ctd\u003e10 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTotal live bacteria\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e30 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*BLB = Billion Live Bacteria\"\u003c\/p\u003e\n\u003cp\u003eNo Refrigeration Required\u003c\/p\u003e\n\u003ch5\u003eNo Added\u003c\/h5\u003e\n\u003ch2\u003eNo Added: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003eNo added: GMOs, wheat, gluten, dairy, lactose, fructose, yeast, nuts, seeds, peanut, soy, egg, fish, shellfish, or animal derivatives.\u003c\/p\u003e\n\u003cp\u003eNo artificial colours, flavours, sweeteners, or preservatives.\u003c\/p\u003e\n\u003cp\u003eSuitable for vegetarians and vegans.\u003c\/p\u003e\n\u003ch5\u003eWarnings and Cautions\u003c\/h5\u003e\n\u003ch2\u003eWarnings and Cautions: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003eIf symptoms persist, consult your healthcare practitioner.\u003c\/p\u003e\n\u003cp\u003eDrink plenty of water.\u003c\/p\u003e\n\u003cp\u003eDo not use when abdominal pain, nausea or vomiting are present, or if you develop diarrhoea.\u003c\/p\u003e\n\u003cp\u003eIf you are pregnant or breastfeeding seek the advice of a healthcare practitioner before using.\u003c\/p\u003e\n\u003cp\u003eResources\u003c\/p\u003e\n\u003ch5\u003eStorage Conditions\u003c\/h5\u003e\n\u003ch2\u003eStorage Conditions: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003eRefrigeration Not Required\u003c\/p\u003e\n\u003ch5\u003eTechnical Information\u003c\/h5\u003e\n\u003ch2\u003eTechnical Information: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003ch3\u003eEFFECT OF ANTIBIOTIC USE ON THE GUT MICROBIOME\u003c\/h3\u003e\n\u003cp\u003eThe use of antibiotics in the Australian community is high, with more than 30 million courses prescribed in 2015 [1]. In order to target a number of different pathogens, most antibiotics have broad-spectrum antimicrobial activity. An unintended consequence of this is that susceptible beneficial (non-pathogenic) strains in the gut microbiome are often adversely affected [2]. While the composition of the gut microbiome generally remains stable within individuals over time, the composition can be disrupted by a number of external factors, in particular, treatment with antibiotics. [3]\u003c\/p\u003e\n\u003cp\u003eNumerous studies have demonstrated that antibiotics can significantly reduce microbial abundance and diversity [3, 4] and induce a state of microbial imbalance, known as intestinal dysbiosis [5]. Intestinal dysbiosis results in the loss of the ability of the gut microbiota to ward off pathogens, which increases susceptibility to infections [6]. Intestinal pathogens weaken gut barrier function and trigger inflammation, which generally results in diarrhoea [7]. As such, a common side effect of antibiotics is antibiotic-associated diarrhea (AAD), which affects 5-39% of patients treated (depending on the type of antibiotic used), and can persist for up to two months after the end of treatment [8].\u003c\/p\u003e\n\u003ch3\u003eBENEFIT OF PROBIOTIC SUPPLEMENTATION\u003c\/h3\u003e\n\u003cp\u003eProbiotics have numerous beneficial effects on the gut microbiome, including inhibiting the growth and proliferation of pathogenic microorganisms, known as colonisation resistance [9]. This is achieved through a number of mechanisms, including the production of acids, which lowers the pH intestinal lumen, suppressing the growth of pathogenic bacteria; the production of hydrogen peroxide, bacteriocins and other substances that are toxic to pathogens; and competitive inhibition of adhesion of the pathogen to the intestinal epithelium9. Probiotics are also able to enhance the gut barrier function (reducing intestinal permeability), and modulate the local immune system [10].\u003c\/p\u003e\n\u003cp\u003eFollowing a course of antibiotics, probiotics may help to restore the abundance and diversity of beneficial gut microbes after the course of antibiotics is completed [11,12] (Figure 1). A recent systematic review investigating the efficacy of probiotics for the restoration of the gut microbiome following a disruptive event (such as a course of antibiotics) found that the probiotic product partially or fully restored the gut microbiota in 83% of the studies included [11].\u003c\/p\u003e\n\u003ch3\u003ePROBIOTICS AND ANTIBIOTIC-ASSOCIATED DIARRHOEA (AAD)\u003c\/h3\u003e\n\u003cp\u003eA recent meta-analysis found that the use of a probiotic may reduce the risk of AAD by 51% (RR 0.49; 95% CI 0.36-0.66; I2=58%) [13]. Lactobacillus rhamnosus GG was found to be the most effective probiotic strain, which demonstrated a 71% reduction in risk of AAD (RR 0.29; 95% CI: 0.150.57)13. The authors concluded that supplementation with probiotics is considered a safe and simple method of AAD prophylaxis [13].\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003e1. Australian Commission on Safety \u0026amp; Quality in Health Care (ACSQHC). AURA 2016: first Australian report on antimicrobial use and resistance in human health. Sydney; 2016.\u003c\/p\u003e\n\u003cp\u003e2. Willing BP, Russell SL, Finlay BB. Shifting the balance: antibiotic effects on host–microbiota mutualism. Nat Rev Microbiol. 2011 Apr;9(4):233–43.\u003c\/p\u003e\n\u003cp\u003e3. Clemente JC, Ursell LK, Parfrey LW, Knight R. The Impact of the Gut Microbiota on Human Health: An Integrative View. Cell. 2012 Mar 16;148(6):1258–70.\u003c\/p\u003e\n\u003cp\u003e4. Antonopoulos DA, Huse SM, Morrison HG, Schmidt TM, Sogin ML, Young VB. Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation. Infect Immun. 2009 Jun;77(6):2367–75.\u003c\/p\u003e\n\u003cp\u003e5. Weiss GA, Hennet T. Mechanisms and consequences of intestinal dysbiosis. Cell Mol Life Sci. 2017 Aug 1;74(16):2959–77.\u003c\/p\u003e\n\u003cp\u003e6. Langdon A, Crook N, Dantas G. The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation. Genome Med [Internet]. 2016 Apr 13 [cited 2019 Jun 13];8. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4831151\/\u003c\/p\u003e\n\u003cp\u003e7. Lawley TD, Walker AW. Intestinal colonization resistance. Immunology. 2013 Jan;138(1):1–11.\u003c\/p\u003e\n\u003cp\u003e8. McFarland LV. Epidemiology, risk factors and treatments for antibiotic-associated diarrhea. Dig Dis Basel Switz. 1998 Oct;16(5):292–307.\u003c\/p\u003e\n\u003cp\u003e9. Williams NT. Probiotics. Am J Health Syst Pharm. 2010 Mar 15;67(6):449–58.\u003c\/p\u003e\n\u003cp\u003e10. Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, et al. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol. 2014 Aug;11(8):506–14.\u003c\/p\u003e\n\u003cp\u003e11. McFarland LV. Use of probiotics to correct dysbiosis of normal microbiota following disease or disruptive events: a systematic review. BMJ Open. 2014 Aug 25;4(8):e005047–e005047.\u003c\/p\u003e\n\u003cp\u003e12. Engelbrektson A, Korzenik JR, Pittler A, Sanders ME, Klaenhammer TR, Leyer G, et al. Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy. J Med Microbiol. 2009 May 1;58(5):663–70.\u003c\/p\u003e\n\u003cp\u003e13. Blaabjerg S, Artzi D, Aabenhus R. Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients—A Systematic Review and Meta-Analysis. 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Using targeted bacterial strains at doses supported by clinical trials, Activated Probiotics seeks to provide tangible improvements in health and well-being with a new generation of evidence-based probiotics.\u003c\/p\u003e\n\u003cp\u003eActivated Probiotics Biome Advanced Probiotic has No Added: GMOs, wheat, gluten, dairy, lactose, fructose, yeast, nuts, seeds, peanut, soy, egg, fish, shellfish, or animal derivatives.\u003c\/p\u003e\n\u003cp\u003eNo artificial colours, flavours, sweeteners, or preservatives.\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp\u003eSuitable for vegetarians and vegans.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eActivated Probiotics Biome Advanced Probiotic AUST L 315959\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eAilments\u003c\/h5\u003e\n\u003ch2\u003eAilments: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports beneficial gut bacteria during antibiotic use\u003c\/li\u003e\n\u003cli\u003eHelps restore beneficial gut bacteria after antibiotic use\u003c\/li\u003e\n\u003cli\u003ePromotes healthy digestion and bowel regularity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eInstructions For Use\u003c\/h5\u003e\n\u003ch2\u003eInstructions For Use: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003eAdults and children over 12 years:\u003c\/p\u003e\n\u003cp\u003etake 1 capsule daily (with or without food), or as directed by your healthcare practitioner.\u003c\/p\u003e\n\u003cp\u003eActivated Probiotics Biome Advanced Probiotic is recommended daily during antibiotic use, starting on the first day of the course. Continue taking Activated Probiotics Biome Advanced Probiotic daily for at least two weeks after completing the course of antibiotics.\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach VegCap Contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus plantarum (DSM6595)\u003c\/td\u003e\n\u003ctd\u003e9 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus plantarum (HEAL 9-DSM 15312)\u003c\/td\u003e\n\u003ctd\u003e0.5 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus paracasei (8700:2-DSM 13434)\u003c\/td\u003e\n\u003ctd\u003e0.5 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus rhamnosus (ATCC 53103)\u003c\/td\u003e\n\u003ctd\u003e5 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus acidophilus (LA02-DSM 21717)\u003c\/td\u003e\n\u003ctd\u003e5 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBifidobacterium animalis ssp. lactis (BS01-LMG P-21384)\u003c\/td\u003e\n\u003ctd\u003e10 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTotal live bacteria\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e30 BLB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*BLB = Billion Live Bacteria\"\u003c\/p\u003e\n\u003cp\u003eNo Refrigeration Required\u003c\/p\u003e\n\u003ch5\u003eNo Added\u003c\/h5\u003e\n\u003ch2\u003eNo Added: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003eNo added: GMOs, wheat, gluten, dairy, lactose, fructose, yeast, nuts, seeds, peanut, soy, egg, fish, shellfish, or animal derivatives.\u003c\/p\u003e\n\u003cp\u003eNo artificial colours, flavours, sweeteners, or preservatives.\u003c\/p\u003e\n\u003cp\u003eSuitable for vegetarians and vegans.\u003c\/p\u003e\n\u003ch5\u003eWarnings and Cautions\u003c\/h5\u003e\n\u003ch2\u003eWarnings and Cautions: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003eIf symptoms persist, consult your healthcare practitioner.\u003c\/p\u003e\n\u003cp\u003eDrink plenty of water.\u003c\/p\u003e\n\u003cp\u003eDo not use when abdominal pain, nausea or vomiting are present, or if you develop diarrhoea.\u003c\/p\u003e\n\u003cp\u003eIf you are pregnant or breastfeeding seek the advice of a healthcare practitioner before using.\u003c\/p\u003e\n\u003cp\u003eResources\u003c\/p\u003e\n\u003ch5\u003eStorage Conditions\u003c\/h5\u003e\n\u003ch2\u003eStorage Conditions: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003eRefrigeration Not Required\u003c\/p\u003e\n\u003ch5\u003eTechnical Information\u003c\/h5\u003e\n\u003ch2\u003eTechnical Information: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003ch3\u003eEFFECT OF ANTIBIOTIC USE ON THE GUT MICROBIOME\u003c\/h3\u003e\n\u003cp\u003eThe use of antibiotics in the Australian community is high, with more than 30 million courses prescribed in 2015 [1]. In order to target a number of different pathogens, most antibiotics have broad-spectrum antimicrobial activity. An unintended consequence of this is that susceptible beneficial (non-pathogenic) strains in the gut microbiome are often adversely affected [2]. While the composition of the gut microbiome generally remains stable within individuals over time, the composition can be disrupted by a number of external factors, in particular, treatment with antibiotics. [3]\u003c\/p\u003e\n\u003cp\u003eNumerous studies have demonstrated that antibiotics can significantly reduce microbial abundance and diversity [3, 4] and induce a state of microbial imbalance, known as intestinal dysbiosis [5]. Intestinal dysbiosis results in the loss of the ability of the gut microbiota to ward off pathogens, which increases susceptibility to infections [6]. Intestinal pathogens weaken gut barrier function and trigger inflammation, which generally results in diarrhoea [7]. As such, a common side effect of antibiotics is antibiotic-associated diarrhea (AAD), which affects 5-39% of patients treated (depending on the type of antibiotic used), and can persist for up to two months after the end of treatment [8].\u003c\/p\u003e\n\u003ch3\u003eBENEFIT OF PROBIOTIC SUPPLEMENTATION\u003c\/h3\u003e\n\u003cp\u003eProbiotics have numerous beneficial effects on the gut microbiome, including inhibiting the growth and proliferation of pathogenic microorganisms, known as colonisation resistance [9]. This is achieved through a number of mechanisms, including the production of acids, which lowers the pH intestinal lumen, suppressing the growth of pathogenic bacteria; the production of hydrogen peroxide, bacteriocins and other substances that are toxic to pathogens; and competitive inhibition of adhesion of the pathogen to the intestinal epithelium9. Probiotics are also able to enhance the gut barrier function (reducing intestinal permeability), and modulate the local immune system [10].\u003c\/p\u003e\n\u003cp\u003eFollowing a course of antibiotics, probiotics may help to restore the abundance and diversity of beneficial gut microbes after the course of antibiotics is completed [11,12] (Figure 1). A recent systematic review investigating the efficacy of probiotics for the restoration of the gut microbiome following a disruptive event (such as a course of antibiotics) found that the probiotic product partially or fully restored the gut microbiota in 83% of the studies included [11].\u003c\/p\u003e\n\u003ch3\u003ePROBIOTICS AND ANTIBIOTIC-ASSOCIATED DIARRHOEA (AAD)\u003c\/h3\u003e\n\u003cp\u003eA recent meta-analysis found that the use of a probiotic may reduce the risk of AAD by 51% (RR 0.49; 95% CI 0.36-0.66; I2=58%) [13]. Lactobacillus rhamnosus GG was found to be the most effective probiotic strain, which demonstrated a 71% reduction in risk of AAD (RR 0.29; 95% CI: 0.150.57)13. The authors concluded that supplementation with probiotics is considered a safe and simple method of AAD prophylaxis [13].\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: Activated Probiotics Biome Advanced Probiotic\u003c\/h2\u003e\n\u003cp\u003e1. Australian Commission on Safety \u0026amp; Quality in Health Care (ACSQHC). AURA 2016: first Australian report on antimicrobial use and resistance in human health. Sydney; 2016.\u003c\/p\u003e\n\u003cp\u003e2. Willing BP, Russell SL, Finlay BB. Shifting the balance: antibiotic effects on host–microbiota mutualism. Nat Rev Microbiol. 2011 Apr;9(4):233–43.\u003c\/p\u003e\n\u003cp\u003e3. Clemente JC, Ursell LK, Parfrey LW, Knight R. The Impact of the Gut Microbiota on Human Health: An Integrative View. Cell. 2012 Mar 16;148(6):1258–70.\u003c\/p\u003e\n\u003cp\u003e4. Antonopoulos DA, Huse SM, Morrison HG, Schmidt TM, Sogin ML, Young VB. Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation. Infect Immun. 2009 Jun;77(6):2367–75.\u003c\/p\u003e\n\u003cp\u003e5. Weiss GA, Hennet T. Mechanisms and consequences of intestinal dysbiosis. Cell Mol Life Sci. 2017 Aug 1;74(16):2959–77.\u003c\/p\u003e\n\u003cp\u003e6. Langdon A, Crook N, Dantas G. The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation. Genome Med [Internet]. 2016 Apr 13 [cited 2019 Jun 13];8. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4831151\/\u003c\/p\u003e\n\u003cp\u003e7. Lawley TD, Walker AW. Intestinal colonization resistance. Immunology. 2013 Jan;138(1):1–11.\u003c\/p\u003e\n\u003cp\u003e8. McFarland LV. Epidemiology, risk factors and treatments for antibiotic-associated diarrhea. Dig Dis Basel Switz. 1998 Oct;16(5):292–307.\u003c\/p\u003e\n\u003cp\u003e9. Williams NT. Probiotics. Am J Health Syst Pharm. 2010 Mar 15;67(6):449–58.\u003c\/p\u003e\n\u003cp\u003e10. Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, et al. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol. 2014 Aug;11(8):506–14.\u003c\/p\u003e\n\u003cp\u003e11. McFarland LV. Use of probiotics to correct dysbiosis of normal microbiota following disease or disruptive events: a systematic review. BMJ Open. 2014 Aug 25;4(8):e005047–e005047.\u003c\/p\u003e\n\u003cp\u003e12. Engelbrektson A, Korzenik JR, Pittler A, Sanders ME, Klaenhammer TR, Leyer G, et al. Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy. J Med Microbiol. 2009 May 1;58(5):663–70.\u003c\/p\u003e\n\u003cp\u003e13. Blaabjerg S, Artzi D, Aabenhus R. Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients—A Systematic Review and Meta-Analysis. Antibiotics. 2017 Oct 12;6(4):21.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}