Metagenics D-Ribose 300g
Directions: Metagenics D-Ribose
1¼ metric teaspoons (5.0 g) is equal to 5.0 g of D-Ribose
- For fatigue – 5g (1¼ tsp) once daily
- For fibromyalgia and chronic fatigue syndrome – 5g (1¼ tsp) three times daily
- For exercise and sports performance – 5g (1¼ tsp) once to twice daily
- For heart health – 5g (1¼ tsp) three times daily
Benefits: Metagenics D-Ribose
KEY ACTIONS:
- Production of ATP (via AMP and ADP synthesis)
- Protects cardiac muscle from ischaemia
- Improves muscle recovery
- Improves exercise tolerance
- Reduces oxidative stress
KEY APPLICATIONS:
- Fatigue
- Fibromyalgia
- Chronic fatigue syndrome
- Exercise and sporting performance
- Cardiac health
Ingredients: Metagenics D-Ribose
Each dose (5.0g) contains: | |
D-Ribose | 5.0g |
D-Ribose is made from glucose and corn. Our own body makes Ribose from glucose.
Excipients: Metagenics D-Ribose
Nil Excipients
Warnings: Metagenics D-Ribose
CONTRAINDICATIONS:
Nil
CAUTIONS:
- Antidiabetic drugs: Ribose may increase the hypoglycaemic effect of oral antihyperglycaemic agents such as the sulfonylureas, biguanides, alfa-glucosidase inhibitors, thiazolidinediones, and meglitinides.3 While additional hypoglycaemic effects may be clinically desirable, blood glucose levels should be monitored.
- Insulin: Ribose may increase the hypoglycaemic effect of insulin.3 While additional hypoglycaemic effects may be clinically desirable, blood glucose levels should be monitored.
Pregnancy and Lactation:
- There are no human clinical studies in this area to date, however animal evidence suggests there are no teratogenic effects.3 Use with caution when there is a clear clinical benefit.
Storage: Metagenics D-Ribose
Store below 30° C
References: Metagenics D-Ribose
- http://chemwiki.ucdavis.edu/Physical_Chemistry/Thermodynamics/Case_Studies/Case_Study%3A_Thermodynamics_of_ATP?hig hlight=chemiosmosis date accessed 9/9/13
- Pasque MK & Wechsler AS. Metabolic intervention to affect myocardial recovery following ischaemia. Annals of Surgery 1984;1(200): 1-12
- Díaz-Flores M, et al. Oral supplementation with glycine reduces oxidative stress in patients with metabolic syndrome, improving their systolic blood pressure. Can J Physiol Pharmacol. 2013 Oct;91(10):855-60
- Seifert JG, Subudhi AW, Fu MX, Riska KL, John JC, Shecterle LM, St Cyr JA. The role of ribose on oxidative stress during hypoxic exercise: a pilot study. J Med Food. 2009 Jun;12(3):690-3.
- Elvin A, Siösteen AK, Nilsson A, Kosek E. Decreased muscle blood flow in fibromyalgia patients during standardised muscle exercise: a contrast media enhanced colour Doppler study. Eur J Pain. 2006 Feb;10(2):137-44.
- Lee JH, et al. Arterial stiffness in female patients with fibromyalgia and its relationship to chronic emotional and physical stress. Korean Circ J. 2011 Oct;41(10):596-602.
- Zarzeczny R et al. Influence of ribose on adenine salvage after intense muscle contractions. J Appl Physiol 2001; 91:1775-1781.
- Myhill S, Booth NE, McLaren-Howard J. Targeting mitochondrial dysfunction in the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) - a clinical audit. Int J Clin Exp Med. 2013;6(1):1-15.
- Bengtsson A, Henriksson KG, Larsson J. Reduced high-energy phosphate levels in the painful muscles of patients with primary fibromyalgia. Arthritis Rheum. 1986 Jul;29(7):817-21.
- Casro-Marrero J, et al. Mitochondrial Dysfunction Be a Differentiating Marker Between Chronic Fatigue Syndrome and Fibromyalgia? Antioxid Redox Signal. 2013 May 29. [Epub ahead of print]
- Addis P, et al. Cellular Protection during Oxidative stress: a potential role for Ribose and Antioxidants. Journal of Dietary Supplements 2012;9(3):178-182.
- Dodd SL, et al. The role of ribose in human skeletal muscle metabolism. Medical Hypotheses 2004;62:819-824.
- Dodd SL, et al. The role of ribose in human skeletal muscle metabolism. Medical Hypotheses 2004;62:819-824.
- Hellsten Y, Skadhauge L & Bangsbo J. Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. Am J Physiol Regul Integr Comp Physiol 2004;286:R182-R188.
- http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id=827&ds=&name=RIBOSE&searchi d=40637790 date accessed 05/04/13.
- Zarzeczny R et al. Influence of ribose on adenine salvage after intense muscle contractions. J Appl Physiol 2001; 91:1775-1781.
- Seifert JG et al. The role of ribose on oxidative stress during hypoxic exercise: a pilot study. J Med Food 2009;12(3):690-693.
- Flanigan R, MacCarter D, Shecterle LM, St Cyr JA. D-ribose aids fatigue in aging adults. J Altern Complement Med. 2010 May;16(5):529-30.
- Teitelbaum JE et al. The use of Ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Alt and Complement Med 2006; 12(9):857-862.
- Teitelbaum J ect al. Treatment of chronic fatigue syndrome and fibromyalgia with Ribose – an open–label multicentre study. The Open Pain Journal 2012;5:32-37.
- Teitelbaum J ect al. Treatment of chronic fatigue syndrome and fibromyalgia with Ribose – an open–label multicentre study. The Open Pain Journal 2012;5:32-37.
- http://naturalstandard.com/databases/herbssupplements/ribose.asp?#undefined date accessed 10/9/13
- Pliml W et al. Effects of ribose on exercise-induced ischaemia in stable coronary artery disease. The Lancet 1992;340:507-510.
- MacCarter D et al. Ribose aids advanced ischaemic heart failure patients. Int J Cardiol 2009;137(1):79-80.
- Pliml W et al. Effects of ribose on exercise-induced ischaemia in stable coronary artery disease. The Lancet 1992;340:507-510.
- Dodd SL, et al. The role of ribose in human skeletal muscle metabolism. Medical Hypotheses 2004;62:819-824.
- Seifert JG et al. The role of ribose on oxidative stress during hypoxic exercise: a pilot study. J Med Food 2009;12(3):690-693.
- Seifert JG et al. The role of ribose on oxidative stress during hypoxic exercise: a pilot study. J Med Food 2009;12(3):690-693.
- Dodd SL, et al. The role of ribose in human skeletal muscle metabolism. Medical Hypotheses 2004;62:819-824.
- Addis P, et al. Cellular Protection during Oxidative stress: a potential role for Ribose and Antioxidants. Journal of Dietary Supplements 2012;9(3):178-182
- Hellsten Y, Skadhauge L & Bangsbo J. Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. Am J Physiol Regul Integr Comp Physiol 2004;286:R182-R188.
- Seifert JG et al. The role of ribose on oxidative stress during hypoxic exercise: a pilot study. J Med Food 2009;12(3):690-693.
- Hellsten Y, Skadhauge L & Bangsbo J. Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. Am J Physiol Regul Integr Comp Physiol 2004;286:R182-R188.
- Van Gammeren D, Falk D and Antonio J. The effects of four weeks of ribose supplementation on body composition and exercise performance in healthy, young, male recreational bodybuilders: a double-blind, placebo-controlled trial. Current Therapeutic Research 2002; 63(8):486-495
- http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id=827&ds=&name=RIBOSE&searchi d=40637790 date accessed 05/04/13.
- http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id=827&ds=&name=RIBOSE&searchi d=40637790 date accessed 05/04/13.
- Griffiths JC, Borzelleca JF, St Cyr J. Lack of oral embryotoxicity/teratogenicity with D-ribose in Wistar rats. Food Chem Toxicol. 2007 Mar;45(3):388-95.