{"id":8205599080678,"title":"Spectrumceuticals SporeBiotic","handle":"spectrumceuticals-sporebiotic","description":"\u003ch2\u003eSpectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eMaintains healthy bowel function\u003c\/em\u003e\u003c\/h3\u003e\n\u003ch3\u003e\u003cem\u003eSupports bowel regularity\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eSpectrumceuticals SporeBiotic \u003cspan style=\"color: rgb(255, 42, 0);\"\u003e10% off RRP\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003ePack Size: 60 Capsules\u003c\/p\u003e\n\u003cp\u003eSpectrumceuticals SporeBiotic Summary:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSpectrumceuticals SporeBiotic contains Bacillus coagulans Unique IS-2 MTCC 5260, Saccharomyces cerevisiae (boulardii) strain CNCM I-3799 and fructo-oligosaccharides.\u003c\/li\u003e\n\u003cli\u003eSpectrumceuticals SporeBiotic maintains healthy bowel function and supports bowel regularity.\u003c\/li\u003e\n\u003cli\u003eSpectrumceuticals SporeBiotic maintains gastrointestinal system health and supports intestinal-friendly\/beneficial flora.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBacillus coagulans Unique IS-2® has been completely characterized by phenotypic and genotypic (Whole Genome Sequencing) methods. Its probiotic properties have also been established and it has been deposited under Patent deposits at:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAmerican Type Culture Collection (ATCC) – assigned number ATCC PTA-11748\u003c\/li\u003e\n\u003cli\u003eMicrobial Type Culture Collection (MTCC) and Gene Bank with an accession number of B. coagulans Unique IS-2® (MTCC 5260)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSpectrumceuticals SporeBiotic has No added yeast, gluten, wheat, dairy, preservatives or artificial colours and flavours. Suitable for vegans.\u003c\/p\u003e\n\u003cp\u003eSpectrumceuticals SporeBiotic AUST L 435112\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eIndications\u003c\/h5\u003e\n\u003ch2\u003eIndications: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMaintain\/support bowel regularity\u003c\/li\u003e\n\u003cli\u003eDecrease\/reduce\/relieve bowel discomfort in healthy adults\u003c\/li\u003e\n\u003cli\u003eMaintain\/support healthy bowel\/colon function\u003c\/li\u003e\n\u003cli\u003eMaintain\/support general health and wellbeing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eActive Ingredients\u003c\/h5\u003e\n\u003ch2\u003eActive Ingredients: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach vegetarian hard capsule contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSaccharomyces cerevisiae (boulardii) strain CNCM I-3799\u003c\/td\u003e\n\u003ctd\u003e250mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBacillus coagulans MTCC 5260\u003c\/td\u003e\n\u003ctd\u003e2 Billion CFU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFructo-oligosaccharides\u003c\/td\u003e\n\u003ctd\u003e100mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eBacillus coagulans Unique IS-2® has been completely characterized by phenotypic and genotypic (Whole Genome Sequencing) methods. Its  probiotic properties have also been established and it has been deposited under Patent deposits at:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAmerican Type Culture Collection (ATCC) – assigned number ATCC PTA-11748\u003c\/li\u003e\n\u003cli\u003eMicrobial Type Culture Collection (MTCC) and Gene Bank with an accession number of B. coagulans Unique IS-2® (MTCC 5260)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eExcipient ingredients: microcrystalline cellulose, colloidal anhydrous silica, magnesium stearate, maltodextrin (maize starch) and size 0 hypromellose capsules.\u003c\/p\u003e\n\u003ch5\u003eAllergen Advice\u003c\/h5\u003e\n\u003ch2\u003eAllergen Advice: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eNo added yeast, gluten, wheat, dairy, preservatives or artificial colours and flavours. Suitable for vegans.\u003c\/p\u003e\n\u003ch5\u003eDose \u0026amp; Administration\u003c\/h5\u003e\n\u003ch2\u003eDose \u0026amp; Administration: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eAdults: take 1 – 2 capsules daily, with water, or as directed by your healthcare professional.\u003c\/p\u003e\n\u003cp\u003eIf symptoms persist consult your healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eNot suitable for children.\u003c\/p\u003e\n\u003cp\u003eBacillus coagulans may affect the way some medicines work, including immunosuppressants.\u003c\/p\u003e\n\u003cp\u003eConsult your healthcare practitioner before taking other medicines.\u003c\/p\u003e\n\u003cp\u003eDrink plenty of water.\u003c\/p\u003e\n\u003cp\u003eDo not use when abdominal pain, nausea or vomiting are present, or if you develop diarrhoea. If you are pregnant or breastfeeding, seek the advice of a healthcare professional before taking this product.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eStore below 25 degrees Celsius away from direct sunlight.\u003c\/p\u003e\n\u003ch5\u003eEducation\u003c\/h5\u003e\n\u003ch2\u003eEducation: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003ch2\u003ePurpose\u003c\/h2\u003e\n\u003cp\u003eA comprehensive gastrointestinal formula designed to support bowel regularity, gut health and function. With robust soil based probiotic and yeast strains this product is shelf stable and has high potential for GI survivability and viability.\u003c\/p\u003e\n\u003cp\u003eFormula contains a prebiotic (fructo-oligosaccharides), spore-based probiotic (Bacillus coagulans), and a probiotic yeast (Saccharomyces boulardii).\u003c\/p\u003e\n\u003ch2\u003e\u003cem\u003eBacillus coagulans\u003c\/em\u003e\u003c\/h2\u003e\n\u003cp\u003eBacillus coagulans form a spore, a temporary structure enveloped by a resistant outer coating. The spore germinates in the intestine, which is favourable for reactivation. The vegetative form of Bacillus coagulans is transient, the bacterium does not inhabit the intestine permanently.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSoil-based bacterial species\u003c\/li\u003e\n\u003cli\u003eSpore-forming\u003c\/li\u003e\n\u003cli\u003eGram-positive bacillus\u003c\/li\u003e\n\u003cli\u003eNon-pathogenic\u003c\/li\u003e\n\u003cli\u003eFacultative anaerobic\u003c\/li\u003e\n\u003cli\u003eLactic acid-producing (produces L+ lactic acid only)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eBenefits of \u003cem\u003eBacillus coagulans\u003c\/em\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eShelf-stable and does not require refrigeration\u003c\/li\u003e\n\u003cli\u003eMaintains viability during preparation, manufacturing and storage until consumption\u003c\/li\u003e\n\u003cli\u003eResistant to high temperatures\u003c\/li\u003e\n\u003cli\u003eResistant to bile acids and acidic conditions of the stomach\u003c\/li\u003e\n\u003cli\u003eSpore-forming probiotics have a transient time of about three to four weeks, while traditional probiotics normally have a transient time of four to seven days. B.\u003c\/li\u003e\n\u003cli\u003eCoagulans were detected in a rat 28 days after consumption.\u003c\/li\u003e\n\u003cli\u003eReported as GRAS (Generally Recognised as Safe)\u003c\/li\u003e\n\u003cli\u003eResistant to antibiotics\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eMechanism of action of \u003cem\u003eBacillus coagulans\u003c\/em\u003e\n\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eModulate the gut microbiota\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eB coagulans Unique IS-2 was able to modulate the gut microbiota by increasing beneficial bacteria. It has been shown to enhance bacterial genera:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus\u003c\/li\u003e\n\u003cli\u003eBifidobacterium\u003c\/li\u003e\n\u003cli\u003eFaecalibacterium\u003c\/li\u003e\n\u003cli\u003eBacteroides\u003c\/li\u003e\n\u003cli\u003eMegamonas\u003c\/li\u003e\n\u003cli\u003eLachnospira\u003c\/li\u003e\n\u003cli\u003eBlautia and\u003c\/li\u003e\n\u003cli\u003eAlistipes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBacterial genera Lactobacillus, Bifidobacterium, and Faecalibacterium have been reported to be protective for mucosal inflammation in the host via several mechanisms, including the up-regulation of the anti-inflammatory cytokine, and down-regulation of inflammatory cytokines.\u003c\/p\u003e\n\u003cp\u003ePopulating the gut with beneficial bacteria restricts the growth of harmful microbes competing for nutrients and environment in the gut.\u003c\/p\u003e\n\u003cp\u003eB. coagulans is capable of restoring microbial imbalance by generating an acidic environment that is harmful to many pathogenic microbes by fermenting polysaccharides.\u003c\/p\u003e\n\u003ch3\u003eAnti-inflammatory properties of \u003cem\u003eBacillus coagulans\u003c\/em\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eIncreases the secretion of IL-10.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eAlleviates digestive discomforts\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eB. coagulans Unique IS2 significantly reduces abdominal pain and increases the number of complete spontaneous bowel movements (CSBM) in IBS patients. Symptoms such as bloating, incomplete evacuation, urgency, straining, passage of gas, bowel habit satisfaction, and stool consistency all improve after taking B. coagulans.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShown efficacy in the treatment of:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eConstipation\u003c\/strong\u003e: Madempudi, R. S. et al. Bacillus coagulans Unique IS2 in constipation: a double-blind, placebo-controlled study. Probiotics Antimicrob. Proteins, https:\/\/doi.org\/10.1007\/s12602-019-09542-9 (2019)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhoea\u003c\/strong\u003e: Sudha M. R., Radkar N. \u0026amp; Maurya, A. Effect of supplementation of probiotic Bacillus coagulans Unique IS-2 (ATCC PAT-11748) on hypercholesterolemic subjects: a clinical study. Int. J. Probiotics Prebiotics 6, 89–93 (2011).)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBacterial vaginosis\u003c\/strong\u003e: Sudha, R. M., Yelikar, K. A. \u0026amp; Deshpande, S. Clinical study of Bacillus coagulans Unique IS-2 (ATCC PTA-11748) in the treatment of patients with bacterial vaginosis. Indian J. Microbiol. 52, 396–399 (2012))\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIBS\u003c\/strong\u003e in adults and children: Sudha, M. R. et al. Efficacy of Bacillus coagulans Unique IS2 in treatment of irritable bowel syndrome in children: a double blind, randomised placebo controlled study. Benef. Microbes 9, 563–572 (2018)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAbdominal pain\u003c\/strong\u003e: Saneian, H. et al. Synbiotic containing Bacillus coagulans and fructo-oligosaccharides for functional abdominal pain in children. Gastro Hepatol. Bed Bench 8, 56–65 (2015)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypercholesteremia\u003c\/strong\u003e: Sudha M. R., Radkar N. \u0026amp; Maurya, A. Effect of supplementation of probiotic Bacillus coagulans Unique IS-2 (ATCC PAT-11748) on hypercholesterolemic subjects: a clinical study. Int. J. Probiotics Prebiotics 6, 89–93 (2011)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver cirrhosis\u003c\/strong\u003e (Pawar, R. R., Pardeshi, M. L. \u0026amp; Ghongane, B. B. Study of effects of probiotic lactobacilli in preventing major complications in patients of liver cirrhosis. Int. J. Res. Pharma. Biomed. Sci. 3, 206–211 (2012)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammatory Bowel Disorders\u003c\/strong\u003e: Bamola VD, Dubey D, Samanta P, et al. Effect of Bacillus coagulans Unique IS-2 in Inflammatory Bowel Disease (IBD): A Randomized Controlled Trial. medRxiv; 2021. DOI: 10.1101\/2021.07.18.21260556.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCaution:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSome experts are critical of spore-forming probiotics as these bacteria can be opportunistic, especially in people who are immunocompromised. If the microbiome isn’t strong, introducing resilient strains, may prove problematic\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\n\u003cem\u003eSaccharomyces boulardii\u003c\/em\u003e (SB)\u003c\/h2\u003e\n\u003cp\u003eNon-pathogenic, non-colonising (transient) and shelf-stable probiotic yeast\u003c\/p\u003e\n\u003cp\u003eOffers protection against pathogenic microorganisms and promotes the healing of the intestinal lining.\u003c\/p\u003e\n\u003cp\u003eTo consider several types of diarrhea, dyspepsia, recurrent Clostridium difficile-associated diseases, restoration of bowel function and flora, adjunctive treatment for \u003cem\u003eH. pylori\u003c\/em\u003e therapy, IBS and Crohn’s disease. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAntibiotic resistant\u003c\/li\u003e\n\u003cli\u003eAnti-diarrheal, reducing; severity, duration and frequency of diarrhea\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eLUMINAL\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAntitoxin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cem\u003eClostridium difficile\u003c\/em\u003e (preventing disease recurrences)\u003c\/li\u003e\n\u003cli\u003eCholera (\u003cem\u003eVibrio cholerae\u003c\/em\u003e)\u003c\/li\u003e\n\u003cli style=\"font-style: italic;\"\u003e\u003cem\u003eE. coli\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSelective Antibacterial\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePreserve tight epithelial cell junctions\u003c\/li\u003e\n\u003cli\u003eSelective bacterial adherence with SB = ↓ pathogenic invasion\u003c\/li\u003e\n\u003cli\u003eAntagonistic to \u003cem\u003eC. albicans\u003c\/em\u003e filamentation, adherence and biofilm formation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eModulate gut flora profile\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNo unwanted effect on healthy gut flora in human controls\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRe-establishment of short chain fatty acids (SCFAs),\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSupporting colon function,\u003c\/li\u003e\n\u003cli\u003eReduce over fermentation in the bowel\u003c\/li\u003e\n\u003cli\u003eIncrease recolonization of normal microbiota = Increase strengthened microbial barrier\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMUCOSAL ANTI-INFLAMMATORY \u0026amp; IMMUNE MODULATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eReduce pro-inflammatory cytokines\u003c\/li\u003e\n\u003cli\u003eIncrease Secretory IgA and IgG = Increase gut immune defence\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFructooligosaccharides (FOS)\u003c\/h2\u003e\n\u003cp\u003eOligosaccharides are composed of linear chains of fructose units, linked by β (2-1) bonds.\u003c\/p\u003e\n\u003cp\u003eFOS transits through the large bowel, is unabsorbed and is hydrolyzed into sugar. These sugars are fermented to short-chain fatty acids (SCFA). SCFA are absorbed by the colon and are the major respiratory fuels for colonocytes, supplying up to 60 to 70% of their energy needs. Acetate and lactate are the main SCFA produced by FOS.\u003c\/p\u003e\n\u003cp\u003eSCFAs are known for their favourable modulatory effects on:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eImmune function\u003c\/li\u003e\n\u003cli\u003egastrointestinal epithelial cell integrity\u003c\/li\u003e\n\u003cli\u003eglucose homeostasis\u003c\/li\u003e\n\u003cli\u003elipid metabolism\u003c\/li\u003e\n\u003cli\u003eregulation of appetite\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003ePrebiotic effects\u003c\/h3\u003e\n\u003cp\u003eFOS selectively promotes the growth and activity of specific spp of bacteria in the gut\u003c\/p\u003e\n\u003cp\u003eIn the colon, FOS specifically promote the growth of Bifidobacterium and Lactobacillus, which in turn produce enzymes that metabolise FOS\u003c\/p\u003e\n\u003cp\u003eThe beneficial bacterium discourages the growth of harmful bacteria such as \u003cem\u003eC. difficile\u003c\/em\u003e and \u003cem\u003eE. coli.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch3\u003eGastrointestinal effects\u003c\/h3\u003e\n\u003cp\u003eFOS increases defecation frequency and reduces bowel transit time in humans. As a prebiotic fibre, FOS promotes colonic fermentation leading to increased faecal biomass.\u003c\/p\u003e\n\u003ch2\u003eSummary of Actives, Needs and Benefits\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center; width: 23.8678%;\"\u003e\u003cstrong\u003eActives\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center; width: 35.6181%;\"\u003e\u003cstrong\u003eNeeds\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center; width: 39.6573%;\"\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8678%;\"\u003e\n\u003cp\u003eBacillus coagulans\u003c\/p\u003e\n\u003cp\u003eSaccharomyces\u003c\/p\u003e\n\u003cp\u003eBoulardii FOS\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 35.6181%;\"\u003e\n\u003cp\u003ePatients with generalised gut disorders. E.g. diagnosed IBS, poor overall gut health, bloating, flatulence, diarrhea, constipation, abdominal pain\u003c\/p\u003e\n\u003cp\u003ePatients with poor immune function\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 39.6573%;\"\u003e\n\u003cp\u003eTherapeutic efficacy for many gut disorders, improved patient signs and symptoms\u003c\/p\u003e\n\u003cp\u003eReduced symptoms associated with Inflammatory Bowel Disease and Irritable bowel Syndrome.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8678%;\"\u003eBacillus coagulans\u003c\/td\u003e\n\u003ctd style=\"width: 35.6181%;\"\u003ePatients with \u003cstrong\u003egastroenteritis\u003c\/strong\u003e and diarrhea (e.g. rotavirus)\u003c\/td\u003e\n\u003ctd style=\"width: 39.6573%;\"\u003e\n\u003cp\u003ePrevention and treatment of diarrhoea.\u003c\/p\u003e\n\u003cp\u003eCompetitive inhibition of pathogenic microorganisms in the gastrointestinal tract*\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8678%;\"\u003eFOS\u003c\/td\u003e\n\u003ctd style=\"width: 35.6181%;\"\u003ePatients with poor gut microbial profile\u003c\/td\u003e\n\u003ctd style=\"width: 39.6573%;\"\u003eEnhanced gut microbiota profile at therapeutic and safe adult dosing. Promotes the growth of the beneficial bacteria in the colon.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8678%;\"\u003e\n\u003cp\u003eSaccharomyces cerevisiae (boulardii) 500mg DBVPG isolate\u003c\/p\u003e\n\u003cp\u003e(10 billion CFU)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 35.6181%;\"\u003e\n\u003cp\u003eAntibiotic associated \u003cstrong\u003ediarrhea\u003c\/strong\u003e, \u003cstrong\u003etraveller’s diarrhea\u003c\/strong\u003e (viral or parasitic)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChronic diarrhea\u003c\/strong\u003e, HIV related or when the origin is unknown *\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eBlastocystis hominis\u003c\/em\u003e \u003cem\u003eClostridium difficile\u003c\/em\u003e, IBS, Crohn’s disease, giardiasis * E. coli overgrowth *, recurrent UTIs H. pylori infection.\u003c\/p\u003e\n\u003cp\u003eTriple therapy dyspepsia and epigastric distress\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 39.6573%;\"\u003e\n\u003cp\u003eReduced severity and duration of diarrhea (all types) *.\u003c\/p\u003e\n\u003cp\u003ePotent, convenient dose for the patient. Protective effect on healthy gut flora *, promotion of secretory IgA\u003c\/p\u003e\n\u003cp\u003eReduced E. coli overgrowth *\u003c\/p\u003e\n\u003cp\u003eIncreased H. pylori eradication rate\u003c\/p\u003e\n\u003cp\u003eReduced GIT distress during triple therapy\u003c\/p\u003e\n\u003cp\u003eInhibited growth of Candida albicans and Salmonella enterica\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eFAQ\u003c\/h5\u003e\n\u003ch2\u003eFAQ: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003ch3\u003eIs Saccharomyces cerevisiae (boulardii) CNCM I-3799 a probiotic?\u003c\/h3\u003e\n\u003cp\u003eA probiotic is a living microorganism (yeast or bacteria) that when taken in adequate amounts, confers a health benefit. Saccharomyces cerevisiae (boulardii) is therefore a probiotic by definition.\u003c\/p\u003e\n\u003ch3\u003eHow do I store Saccharomyces cerevisiae (boulardii) fridge free probiotics, are they stable?\u003c\/h3\u003e\n\u003cp\u003eFor fridge-free, shelf-stable probiotics, please store in a cool dry place below 25°C, or refrigerate if you like. Prolonged excessive moisture and high heat will accelerate probiotic deterioration. High temperatures can kill probiotics, and exposure to temperatures above 46°C can increase the rate of loss rapidly.\u003c\/p\u003e\n\u003ch3\u003eDo you have allergen and certification for the CNCM I-3799?\u003c\/h3\u003e\n\u003cp\u003eThe ingredient is gluten-free, dairy free, non-GMO verified, Halal and Kosher.\u003c\/p\u003e\n\u003cp\u003eWe add no fillers or binders to this ingredient, only encapsulation in a hypromellose capsule suitable for vegans and vegetarians.\u003c\/p\u003e\n\u003cp\u003eHow do I store Bacillus coagulans Unique IS-2 fridge free probiotics, are they stable?\u003cbr\u003eFor fridge-free, shelf-stable probiotics, please store in a cool dry place below 25°C, or refrigerate if you like. Prolonged excessive moisture and high heat will accelerate probiotic deterioration. High temperatures can kill probiotics, and exposure to temperatures above 46°C can increase the rate of loss rapidly.\u003cbr\u003e\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2023-05-06T18:22:26+10:00","created_at":"2023-05-06T17:59:59+10:00","vendor":"Spectrumceuticals","type":"Spectrumceuticals Naturopathic Medicines","tags":["Naturopathic","PB","Refrigeration Not Required","Saccharomyces cerevisiae (boulardii)","Spectrumceuticals"],"price":5850,"price_min":5850,"price_max":5850,"available":true,"price_varies":false,"compare_at_price":6500,"compare_at_price_min":6500,"compare_at_price_max":6500,"compare_at_price_varies":false,"variants":[{"id":43767927374054,"title":"60 Capsules","option1":"60 Capsules","option2":null,"option3":null,"sku":"SpcSporeBiotic60C","requires_shipping":true,"taxable":true,"featured_image":{"id":43640138432742,"product_id":8205599080678,"position":1,"created_at":"2025-03-12T13:53:41+11:00","updated_at":"2025-03-12T13:54:42+11:00","alt":"Spectrumceuticals SporeBiotic 60caps 10% off RRP at HealthMasters Spectrumceuticals","width":1200,"height":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/SpectrumceuticalsSporeBiotic60caps10_offRRPatHealthMastersSpectrumceuticals.png?v=1741748082","variant_ids":[43767927374054]},"available":true,"name":"Spectrumceuticals SporeBiotic - 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Its probiotic properties have also been established and it has been deposited under Patent deposits at:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAmerican Type Culture Collection (ATCC) – assigned number ATCC PTA-11748\u003c\/li\u003e\n\u003cli\u003eMicrobial Type Culture Collection (MTCC) and Gene Bank with an accession number of B. coagulans Unique IS-2® (MTCC 5260)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSpectrumceuticals SporeBiotic has No added yeast, gluten, wheat, dairy, preservatives or artificial colours and flavours. Suitable for vegans.\u003c\/p\u003e\n\u003cp\u003eSpectrumceuticals SporeBiotic AUST L 435112\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eIndications\u003c\/h5\u003e\n\u003ch2\u003eIndications: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMaintain\/support bowel regularity\u003c\/li\u003e\n\u003cli\u003eDecrease\/reduce\/relieve bowel discomfort in healthy adults\u003c\/li\u003e\n\u003cli\u003eMaintain\/support healthy bowel\/colon function\u003c\/li\u003e\n\u003cli\u003eMaintain\/support general health and wellbeing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eActive Ingredients\u003c\/h5\u003e\n\u003ch2\u003eActive Ingredients: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach vegetarian hard capsule contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSaccharomyces cerevisiae (boulardii) strain CNCM I-3799\u003c\/td\u003e\n\u003ctd\u003e250mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBacillus coagulans MTCC 5260\u003c\/td\u003e\n\u003ctd\u003e2 Billion CFU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFructo-oligosaccharides\u003c\/td\u003e\n\u003ctd\u003e100mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eBacillus coagulans Unique IS-2® has been completely characterized by phenotypic and genotypic (Whole Genome Sequencing) methods. Its  probiotic properties have also been established and it has been deposited under Patent deposits at:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAmerican Type Culture Collection (ATCC) – assigned number ATCC PTA-11748\u003c\/li\u003e\n\u003cli\u003eMicrobial Type Culture Collection (MTCC) and Gene Bank with an accession number of B. coagulans Unique IS-2® (MTCC 5260)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eExcipient ingredients: microcrystalline cellulose, colloidal anhydrous silica, magnesium stearate, maltodextrin (maize starch) and size 0 hypromellose capsules.\u003c\/p\u003e\n\u003ch5\u003eAllergen Advice\u003c\/h5\u003e\n\u003ch2\u003eAllergen Advice: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eNo added yeast, gluten, wheat, dairy, preservatives or artificial colours and flavours. Suitable for vegans.\u003c\/p\u003e\n\u003ch5\u003eDose \u0026amp; Administration\u003c\/h5\u003e\n\u003ch2\u003eDose \u0026amp; Administration: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eAdults: take 1 – 2 capsules daily, with water, or as directed by your healthcare professional.\u003c\/p\u003e\n\u003cp\u003eIf symptoms persist consult your healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eNot suitable for children.\u003c\/p\u003e\n\u003cp\u003eBacillus coagulans may affect the way some medicines work, including immunosuppressants.\u003c\/p\u003e\n\u003cp\u003eConsult your healthcare practitioner before taking other medicines.\u003c\/p\u003e\n\u003cp\u003eDrink plenty of water.\u003c\/p\u003e\n\u003cp\u003eDo not use when abdominal pain, nausea or vomiting are present, or if you develop diarrhoea. If you are pregnant or breastfeeding, seek the advice of a healthcare professional before taking this product.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003cp\u003eStore below 25 degrees Celsius away from direct sunlight.\u003c\/p\u003e\n\u003ch5\u003eEducation\u003c\/h5\u003e\n\u003ch2\u003eEducation: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003ch2\u003ePurpose\u003c\/h2\u003e\n\u003cp\u003eA comprehensive gastrointestinal formula designed to support bowel regularity, gut health and function. With robust soil based probiotic and yeast strains this product is shelf stable and has high potential for GI survivability and viability.\u003c\/p\u003e\n\u003cp\u003eFormula contains a prebiotic (fructo-oligosaccharides), spore-based probiotic (Bacillus coagulans), and a probiotic yeast (Saccharomyces boulardii).\u003c\/p\u003e\n\u003ch2\u003e\u003cem\u003eBacillus coagulans\u003c\/em\u003e\u003c\/h2\u003e\n\u003cp\u003eBacillus coagulans form a spore, a temporary structure enveloped by a resistant outer coating. The spore germinates in the intestine, which is favourable for reactivation. The vegetative form of Bacillus coagulans is transient, the bacterium does not inhabit the intestine permanently.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSoil-based bacterial species\u003c\/li\u003e\n\u003cli\u003eSpore-forming\u003c\/li\u003e\n\u003cli\u003eGram-positive bacillus\u003c\/li\u003e\n\u003cli\u003eNon-pathogenic\u003c\/li\u003e\n\u003cli\u003eFacultative anaerobic\u003c\/li\u003e\n\u003cli\u003eLactic acid-producing (produces L+ lactic acid only)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eBenefits of \u003cem\u003eBacillus coagulans\u003c\/em\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eShelf-stable and does not require refrigeration\u003c\/li\u003e\n\u003cli\u003eMaintains viability during preparation, manufacturing and storage until consumption\u003c\/li\u003e\n\u003cli\u003eResistant to high temperatures\u003c\/li\u003e\n\u003cli\u003eResistant to bile acids and acidic conditions of the stomach\u003c\/li\u003e\n\u003cli\u003eSpore-forming probiotics have a transient time of about three to four weeks, while traditional probiotics normally have a transient time of four to seven days. B.\u003c\/li\u003e\n\u003cli\u003eCoagulans were detected in a rat 28 days after consumption.\u003c\/li\u003e\n\u003cli\u003eReported as GRAS (Generally Recognised as Safe)\u003c\/li\u003e\n\u003cli\u003eResistant to antibiotics\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eMechanism of action of \u003cem\u003eBacillus coagulans\u003c\/em\u003e\n\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eModulate the gut microbiota\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eB coagulans Unique IS-2 was able to modulate the gut microbiota by increasing beneficial bacteria. It has been shown to enhance bacterial genera:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus\u003c\/li\u003e\n\u003cli\u003eBifidobacterium\u003c\/li\u003e\n\u003cli\u003eFaecalibacterium\u003c\/li\u003e\n\u003cli\u003eBacteroides\u003c\/li\u003e\n\u003cli\u003eMegamonas\u003c\/li\u003e\n\u003cli\u003eLachnospira\u003c\/li\u003e\n\u003cli\u003eBlautia and\u003c\/li\u003e\n\u003cli\u003eAlistipes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBacterial genera Lactobacillus, Bifidobacterium, and Faecalibacterium have been reported to be protective for mucosal inflammation in the host via several mechanisms, including the up-regulation of the anti-inflammatory cytokine, and down-regulation of inflammatory cytokines.\u003c\/p\u003e\n\u003cp\u003ePopulating the gut with beneficial bacteria restricts the growth of harmful microbes competing for nutrients and environment in the gut.\u003c\/p\u003e\n\u003cp\u003eB. coagulans is capable of restoring microbial imbalance by generating an acidic environment that is harmful to many pathogenic microbes by fermenting polysaccharides.\u003c\/p\u003e\n\u003ch3\u003eAnti-inflammatory properties of \u003cem\u003eBacillus coagulans\u003c\/em\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eIncreases the secretion of IL-10.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eAlleviates digestive discomforts\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eB. coagulans Unique IS2 significantly reduces abdominal pain and increases the number of complete spontaneous bowel movements (CSBM) in IBS patients. Symptoms such as bloating, incomplete evacuation, urgency, straining, passage of gas, bowel habit satisfaction, and stool consistency all improve after taking B. coagulans.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShown efficacy in the treatment of:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eConstipation\u003c\/strong\u003e: Madempudi, R. S. et al. Bacillus coagulans Unique IS2 in constipation: a double-blind, placebo-controlled study. Probiotics Antimicrob. Proteins, https:\/\/doi.org\/10.1007\/s12602-019-09542-9 (2019)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhoea\u003c\/strong\u003e: Sudha M. R., Radkar N. \u0026amp; Maurya, A. Effect of supplementation of probiotic Bacillus coagulans Unique IS-2 (ATCC PAT-11748) on hypercholesterolemic subjects: a clinical study. Int. J. Probiotics Prebiotics 6, 89–93 (2011).)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBacterial vaginosis\u003c\/strong\u003e: Sudha, R. M., Yelikar, K. A. \u0026amp; Deshpande, S. Clinical study of Bacillus coagulans Unique IS-2 (ATCC PTA-11748) in the treatment of patients with bacterial vaginosis. Indian J. Microbiol. 52, 396–399 (2012))\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIBS\u003c\/strong\u003e in adults and children: Sudha, M. R. et al. Efficacy of Bacillus coagulans Unique IS2 in treatment of irritable bowel syndrome in children: a double blind, randomised placebo controlled study. Benef. Microbes 9, 563–572 (2018)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAbdominal pain\u003c\/strong\u003e: Saneian, H. et al. Synbiotic containing Bacillus coagulans and fructo-oligosaccharides for functional abdominal pain in children. Gastro Hepatol. Bed Bench 8, 56–65 (2015)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypercholesteremia\u003c\/strong\u003e: Sudha M. R., Radkar N. \u0026amp; Maurya, A. Effect of supplementation of probiotic Bacillus coagulans Unique IS-2 (ATCC PAT-11748) on hypercholesterolemic subjects: a clinical study. Int. J. Probiotics Prebiotics 6, 89–93 (2011)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver cirrhosis\u003c\/strong\u003e (Pawar, R. R., Pardeshi, M. L. \u0026amp; Ghongane, B. B. Study of effects of probiotic lactobacilli in preventing major complications in patients of liver cirrhosis. Int. J. Res. Pharma. Biomed. Sci. 3, 206–211 (2012)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammatory Bowel Disorders\u003c\/strong\u003e: Bamola VD, Dubey D, Samanta P, et al. Effect of Bacillus coagulans Unique IS-2 in Inflammatory Bowel Disease (IBD): A Randomized Controlled Trial. medRxiv; 2021. DOI: 10.1101\/2021.07.18.21260556.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCaution:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSome experts are critical of spore-forming probiotics as these bacteria can be opportunistic, especially in people who are immunocompromised. If the microbiome isn’t strong, introducing resilient strains, may prove problematic\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\n\u003cem\u003eSaccharomyces boulardii\u003c\/em\u003e (SB)\u003c\/h2\u003e\n\u003cp\u003eNon-pathogenic, non-colonising (transient) and shelf-stable probiotic yeast\u003c\/p\u003e\n\u003cp\u003eOffers protection against pathogenic microorganisms and promotes the healing of the intestinal lining.\u003c\/p\u003e\n\u003cp\u003eTo consider several types of diarrhea, dyspepsia, recurrent Clostridium difficile-associated diseases, restoration of bowel function and flora, adjunctive treatment for \u003cem\u003eH. pylori\u003c\/em\u003e therapy, IBS and Crohn’s disease. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAntibiotic resistant\u003c\/li\u003e\n\u003cli\u003eAnti-diarrheal, reducing; severity, duration and frequency of diarrhea\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eLUMINAL\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAntitoxin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cem\u003eClostridium difficile\u003c\/em\u003e (preventing disease recurrences)\u003c\/li\u003e\n\u003cli\u003eCholera (\u003cem\u003eVibrio cholerae\u003c\/em\u003e)\u003c\/li\u003e\n\u003cli style=\"font-style: italic;\"\u003e\u003cem\u003eE. coli\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSelective Antibacterial\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePreserve tight epithelial cell junctions\u003c\/li\u003e\n\u003cli\u003eSelective bacterial adherence with SB = ↓ pathogenic invasion\u003c\/li\u003e\n\u003cli\u003eAntagonistic to \u003cem\u003eC. albicans\u003c\/em\u003e filamentation, adherence and biofilm formation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eModulate gut flora profile\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNo unwanted effect on healthy gut flora in human controls\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRe-establishment of short chain fatty acids (SCFAs),\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSupporting colon function,\u003c\/li\u003e\n\u003cli\u003eReduce over fermentation in the bowel\u003c\/li\u003e\n\u003cli\u003eIncrease recolonization of normal microbiota = Increase strengthened microbial barrier\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMUCOSAL ANTI-INFLAMMATORY \u0026amp; IMMUNE MODULATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eReduce pro-inflammatory cytokines\u003c\/li\u003e\n\u003cli\u003eIncrease Secretory IgA and IgG = Increase gut immune defence\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFructooligosaccharides (FOS)\u003c\/h2\u003e\n\u003cp\u003eOligosaccharides are composed of linear chains of fructose units, linked by β (2-1) bonds.\u003c\/p\u003e\n\u003cp\u003eFOS transits through the large bowel, is unabsorbed and is hydrolyzed into sugar. These sugars are fermented to short-chain fatty acids (SCFA). SCFA are absorbed by the colon and are the major respiratory fuels for colonocytes, supplying up to 60 to 70% of their energy needs. Acetate and lactate are the main SCFA produced by FOS.\u003c\/p\u003e\n\u003cp\u003eSCFAs are known for their favourable modulatory effects on:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eImmune function\u003c\/li\u003e\n\u003cli\u003egastrointestinal epithelial cell integrity\u003c\/li\u003e\n\u003cli\u003eglucose homeostasis\u003c\/li\u003e\n\u003cli\u003elipid metabolism\u003c\/li\u003e\n\u003cli\u003eregulation of appetite\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003ePrebiotic effects\u003c\/h3\u003e\n\u003cp\u003eFOS selectively promotes the growth and activity of specific spp of bacteria in the gut\u003c\/p\u003e\n\u003cp\u003eIn the colon, FOS specifically promote the growth of Bifidobacterium and Lactobacillus, which in turn produce enzymes that metabolise FOS\u003c\/p\u003e\n\u003cp\u003eThe beneficial bacterium discourages the growth of harmful bacteria such as \u003cem\u003eC. difficile\u003c\/em\u003e and \u003cem\u003eE. coli.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch3\u003eGastrointestinal effects\u003c\/h3\u003e\n\u003cp\u003eFOS increases defecation frequency and reduces bowel transit time in humans. As a prebiotic fibre, FOS promotes colonic fermentation leading to increased faecal biomass.\u003c\/p\u003e\n\u003ch2\u003eSummary of Actives, Needs and Benefits\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center; width: 23.8678%;\"\u003e\u003cstrong\u003eActives\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center; width: 35.6181%;\"\u003e\u003cstrong\u003eNeeds\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center; width: 39.6573%;\"\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8678%;\"\u003e\n\u003cp\u003eBacillus coagulans\u003c\/p\u003e\n\u003cp\u003eSaccharomyces\u003c\/p\u003e\n\u003cp\u003eBoulardii FOS\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 35.6181%;\"\u003e\n\u003cp\u003ePatients with generalised gut disorders. E.g. diagnosed IBS, poor overall gut health, bloating, flatulence, diarrhea, constipation, abdominal pain\u003c\/p\u003e\n\u003cp\u003ePatients with poor immune function\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 39.6573%;\"\u003e\n\u003cp\u003eTherapeutic efficacy for many gut disorders, improved patient signs and symptoms\u003c\/p\u003e\n\u003cp\u003eReduced symptoms associated with Inflammatory Bowel Disease and Irritable bowel Syndrome.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8678%;\"\u003eBacillus coagulans\u003c\/td\u003e\n\u003ctd style=\"width: 35.6181%;\"\u003ePatients with \u003cstrong\u003egastroenteritis\u003c\/strong\u003e and diarrhea (e.g. rotavirus)\u003c\/td\u003e\n\u003ctd style=\"width: 39.6573%;\"\u003e\n\u003cp\u003ePrevention and treatment of diarrhoea.\u003c\/p\u003e\n\u003cp\u003eCompetitive inhibition of pathogenic microorganisms in the gastrointestinal tract*\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8678%;\"\u003eFOS\u003c\/td\u003e\n\u003ctd style=\"width: 35.6181%;\"\u003ePatients with poor gut microbial profile\u003c\/td\u003e\n\u003ctd style=\"width: 39.6573%;\"\u003eEnhanced gut microbiota profile at therapeutic and safe adult dosing. Promotes the growth of the beneficial bacteria in the colon.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8678%;\"\u003e\n\u003cp\u003eSaccharomyces cerevisiae (boulardii) 500mg DBVPG isolate\u003c\/p\u003e\n\u003cp\u003e(10 billion CFU)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 35.6181%;\"\u003e\n\u003cp\u003eAntibiotic associated \u003cstrong\u003ediarrhea\u003c\/strong\u003e, \u003cstrong\u003etraveller’s diarrhea\u003c\/strong\u003e (viral or parasitic)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChronic diarrhea\u003c\/strong\u003e, HIV related or when the origin is unknown *\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eBlastocystis hominis\u003c\/em\u003e \u003cem\u003eClostridium difficile\u003c\/em\u003e, IBS, Crohn’s disease, giardiasis * E. coli overgrowth *, recurrent UTIs H. pylori infection.\u003c\/p\u003e\n\u003cp\u003eTriple therapy dyspepsia and epigastric distress\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 39.6573%;\"\u003e\n\u003cp\u003eReduced severity and duration of diarrhea (all types) *.\u003c\/p\u003e\n\u003cp\u003ePotent, convenient dose for the patient. Protective effect on healthy gut flora *, promotion of secretory IgA\u003c\/p\u003e\n\u003cp\u003eReduced E. coli overgrowth *\u003c\/p\u003e\n\u003cp\u003eIncreased H. pylori eradication rate\u003c\/p\u003e\n\u003cp\u003eReduced GIT distress during triple therapy\u003c\/p\u003e\n\u003cp\u003eInhibited growth of Candida albicans and Salmonella enterica\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eFAQ\u003c\/h5\u003e\n\u003ch2\u003eFAQ: Spectrumceuticals SporeBiotic\u003c\/h2\u003e\n\u003ch3\u003eIs Saccharomyces cerevisiae (boulardii) CNCM I-3799 a probiotic?\u003c\/h3\u003e\n\u003cp\u003eA probiotic is a living microorganism (yeast or bacteria) that when taken in adequate amounts, confers a health benefit. Saccharomyces cerevisiae (boulardii) is therefore a probiotic by definition.\u003c\/p\u003e\n\u003ch3\u003eHow do I store Saccharomyces cerevisiae (boulardii) fridge free probiotics, are they stable?\u003c\/h3\u003e\n\u003cp\u003eFor fridge-free, shelf-stable probiotics, please store in a cool dry place below 25°C, or refrigerate if you like. Prolonged excessive moisture and high heat will accelerate probiotic deterioration. High temperatures can kill probiotics, and exposure to temperatures above 46°C can increase the rate of loss rapidly.\u003c\/p\u003e\n\u003ch3\u003eDo you have allergen and certification for the CNCM I-3799?\u003c\/h3\u003e\n\u003cp\u003eThe ingredient is gluten-free, dairy free, non-GMO verified, Halal and Kosher.\u003c\/p\u003e\n\u003cp\u003eWe add no fillers or binders to this ingredient, only encapsulation in a hypromellose capsule suitable for vegans and vegetarians.\u003c\/p\u003e\n\u003cp\u003eHow do I store Bacillus coagulans Unique IS-2 fridge free probiotics, are they stable?\u003cbr\u003eFor fridge-free, shelf-stable probiotics, please store in a cool dry place below 25°C, or refrigerate if you like. Prolonged excessive moisture and high heat will accelerate probiotic deterioration. High temperatures can kill probiotics, and exposure to temperatures above 46°C can increase the rate of loss rapidly.\u003cbr\u003e\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}