{"id":7693514342630,"title":"Bioclinic Naturals Opti B12 5mg","handle":"bioclinic-naturals-opti-b12","description":"\u003ch2\u003eBioclinic Naturals Opti B12 5mg\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eBiologically Active Form\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eSizes: 60 Sublingual Tablets\u003c\/p\u003e\n\u003cp\u003eBioclinic Naturals Opti B12 Feature Summary:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBioclinic Naturals Opti B12 contains the bioactive form of vitamin B12: Co-methylcobalamin.\u003c\/li\u003e\n\u003cli\u003eThis form has enhanced bioavailability and is in a convenient, sublingual format for rapid absorption into the bloodstream.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBioclinic Naturals Opti B12 AUST L299716\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eBenefits\u003c\/h5\u003e\n\u003ch2\u003eBenefits: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003cp\u003eCo-methylcobalamin bypasses active absorption routes enabling the restoration of normal B12 levels even in individuals with impaired absorptive capacity1-3\u003c\/p\u003e\n\u003cp\u003eProvides B12 at a dose of 5 mg per day in sublingual tablet format, allowing for a fast-acting delivery system, directly into the bloodstream\u003c\/p\u003e\n\u003cp\u003eCo-methylcobalamin supports sustained B12 levels in the body compared to cyanocobalamin due to decreased urinary excretion4\u003c\/p\u003e\n\u003cp\u003eSuitable for vegetarians\u003c\/p\u003e\n\u003ch5\u003eRecommended Use\u003c\/h5\u003e\n\u003ch2\u003eRecommended Use: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003cp\u003eAdults:\u003c\/p\u003e\n\u003cp\u003e1 tablet (B12 5000ug) per day or as directed by a health care practitioner.\u003c\/p\u003e\n\u003cp\u003eSublingual is oral delivery dissolved under the tongue, without chewing or swallowing. Absorption is very quick, and higher levels are achieved in the bloodstream by sublingual routes than when swallowed because the sublingual route avoids first-pass metabolism by the liver.\u003c\/p\u003e\n\u003ch5\u003eMedicinal Ingredients\u003c\/h5\u003e\n\u003ch2\u003eMedicinal Ingredients: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach Tablet Contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMecobalamin (co-methylcobalamin) (active vitamin B12)\u003c\/td\u003e\n\u003ctd\u003e5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eKey Features and Benefits\u003c\/h5\u003e\n\u003ch2\u003eKey Features and Benefits: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eHelps prevent the dietary B12 deficiency.\u003c\/li\u003e\n\u003cli\u003eHelps promote body utilisation of vitamin B12.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 is a cofactor in enzymatic reactions with diverse physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as the conversion of homocysteine to methionine by methionine synthase, which is then converted into S-adenosylmethionine. In vitamin B12 deficiency, folate may accumulate in serum as a result of the slowing of the vitamin B12-dependent methyltransferase.5,7\u003c\/li\u003e\n\u003cli\u003eB12 is required for the synthesis of fatty acids in myelin and for DNA synthesis in conjunction with folate.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 lowers homocysteine levels for protective cardiovascular benefits.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eContraindications\u003cbr\u003e\n\u003c\/h5\u003e\n\u003ch2\u003eContraindications: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003cp\u003eWARNINGS: Vitamins can only be of assistance if the dietary vitamin intake is inadequate.\u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eParry TE. Megaloblastic anaemia in the elderly. Baillieres Clin Haematol. 1987 Jun;1(2):315-53.\u003c\/li\u003e\n\u003cli\u003eKim HI, Hyung WJ, Song KJ, Choi SH, Kim CB, Noh SH. Oral vitamin B12 replacement: an effective treatment for vitamin B12 deficiency after total gastrectomy in gastric cancer patients. Ann Surg Oncol. 2011 Dec;18(13):371-7.\u003c\/li\u003e\n\u003cli\u003eBolaman Z, Kadikoylu G, Yukselen V, Yavasoglu I, Barutca S, Senturk T. Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study. Clin Ther. 2003 Dec;25(12):3124-34.\u003c\/li\u003e\n\u003cli\u003eOkuda K, Yashima K, Kitazaki T, et al. Intestinal absorption and concurrent chemical changes of methylcobalamin. J Lab Clin Med 1973;81:557-567.\u003c\/li\u003e\n\u003cli\u003eCarmel R, Cobalamin (Vitamin B12) in Shils ME, et. al., eds., Modern Nutrition in Health and Disease, Lippincott Williams and Wilkens, Philadelphia, 2006, 482-497.\u003c\/li\u003e\n\u003cli\u003eWong CW1.Vitamin B12 deficiency in the elderly: is it worth screening? Hong Kong Med J. 2015 Apr;21(2):155-5.\u003c\/li\u003e\n\u003cli\u003ePawlak R, Parrot JS, Raj S et al. Understanding Vitamin B12. Am J Lifestyle Med. 2012 January; 7(1):60-65.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2022-10-11T16:13:54+11:00","created_at":"2022-03-19T11:41:53+11:00","vendor":"Bioclinic Naturals","type":"Bioclinic Naturals Naturopathic Medicines","tags":["Bioclinic Naturals","Naturopathic","PB","Sublingual B12","Vitamin B12"],"price":3146,"price_min":3146,"price_max":3146,"available":true,"price_varies":false,"compare_at_price":3495,"compare_at_price_min":3495,"compare_at_price_max":3495,"compare_at_price_varies":false,"variants":[{"id":42695206076646,"title":"60 Sublingual Tablets","option1":"60 Sublingual Tablets","option2":null,"option3":null,"sku":"BcNOptiB1260T","requires_shipping":true,"taxable":true,"featured_image":{"id":37179508818150,"product_id":7693514342630,"position":1,"created_at":"2022-03-19T12:03:31+11:00","updated_at":"2022-03-19T12:04:11+11:00","alt":"Bioclinic Naturals Opti B12 60caps 10% off RRP at HealthMasters Bioclinic Naturals","width":648,"height":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioclinicNaturalsOptiB1260caps10_offRRPatHealthMastersBioclinicNaturals.png?v=1647651851","variant_ids":[42695206076646]},"available":true,"name":"Bioclinic Naturals Opti B12 5mg - 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Absorption is very quick, and higher levels are achieved in the bloodstream by sublingual routes than when swallowed because the sublingual route avoids first-pass metabolism by the liver.\u003c\/p\u003e\n\u003ch5\u003eMedicinal Ingredients\u003c\/h5\u003e\n\u003ch2\u003eMedicinal Ingredients: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach Tablet Contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMecobalamin (co-methylcobalamin) (active vitamin B12)\u003c\/td\u003e\n\u003ctd\u003e5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eKey Features and Benefits\u003c\/h5\u003e\n\u003ch2\u003eKey Features and Benefits: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eHelps prevent the dietary B12 deficiency.\u003c\/li\u003e\n\u003cli\u003eHelps promote body utilisation of vitamin B12.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 is a cofactor in enzymatic reactions with diverse physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as the conversion of homocysteine to methionine by methionine synthase, which is then converted into S-adenosylmethionine. In vitamin B12 deficiency, folate may accumulate in serum as a result of the slowing of the vitamin B12-dependent methyltransferase.5,7\u003c\/li\u003e\n\u003cli\u003eB12 is required for the synthesis of fatty acids in myelin and for DNA synthesis in conjunction with folate.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 lowers homocysteine levels for protective cardiovascular benefits.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eContraindications\u003cbr\u003e\n\u003c\/h5\u003e\n\u003ch2\u003eContraindications: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003cp\u003eWARNINGS: Vitamins can only be of assistance if the dietary vitamin intake is inadequate.\u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: Bioclinic Naturals Opti B12\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eParry TE. Megaloblastic anaemia in the elderly. Baillieres Clin Haematol. 1987 Jun;1(2):315-53.\u003c\/li\u003e\n\u003cli\u003eKim HI, Hyung WJ, Song KJ, Choi SH, Kim CB, Noh SH. Oral vitamin B12 replacement: an effective treatment for vitamin B12 deficiency after total gastrectomy in gastric cancer patients. Ann Surg Oncol. 2011 Dec;18(13):371-7.\u003c\/li\u003e\n\u003cli\u003eBolaman Z, Kadikoylu G, Yukselen V, Yavasoglu I, Barutca S, Senturk T. Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study. Clin Ther. 2003 Dec;25(12):3124-34.\u003c\/li\u003e\n\u003cli\u003eOkuda K, Yashima K, Kitazaki T, et al. Intestinal absorption and concurrent chemical changes of methylcobalamin. J Lab Clin Med 1973;81:557-567.\u003c\/li\u003e\n\u003cli\u003eCarmel R, Cobalamin (Vitamin B12) in Shils ME, et. al., eds., Modern Nutrition in Health and Disease, Lippincott Williams and Wilkens, Philadelphia, 2006, 482-497.\u003c\/li\u003e\n\u003cli\u003eWong CW1.Vitamin B12 deficiency in the elderly: is it worth screening? Hong Kong Med J. 2015 Apr;21(2):155-5.\u003c\/li\u003e\n\u003cli\u003ePawlak R, Parrot JS, Raj S et al. Understanding Vitamin B12. Am J Lifestyle Med. 2012 January; 7(1):60-65.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c!-- \/TABS --\u003e"}