{"id":5281643397278,"title":"BioCeuticals PepZin Pro 60 caps","handle":"bioceuticals-pepzin-pro-60-caps","description":"\u003ch2\u003eBioCeuticals PepZin Pro 60 caps\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eTo Reduce and Relieve the Symptoms of Mild Gastritis and Support Gut Flora\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003eDiscontinued by the manufacturer for recommended alternatives see\u003c\/span\u003e \u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-pepzin-pro-60-caps?_pos=1\u0026amp;_psq=PepZn\u0026amp;_ss=e\u0026amp;_v=1.0#similar-products\" title=\"BioCeuticals PepZin Pro Similar Products 10% off RRP | HealthMasters BioCeuticals\" rel=\"noopener\" target=\"_blank\"\u003eSimilar Products TAB\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eAvailable In Sizes: 60 capsules\u003c\/p\u003e\n\u003cp\u003eBioCeuticals PepZin Pro Summary:\u003c\/p\u003e\n\u003cp\u003ePolaprezinc (zinc carnosine) PepZinGI a novel crystalline chelated compound consisting of L-Carnosine (N-ß-alanyl-L-histadine), is a highly bioavailable form of zinc and helps relieve symptoms of mild gastritis including gastrointestinal pain, nausea, abdominal distention and heartburn.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSupplementation with probiotics, including Lacidofil, Lactobacillus rhamnosus R0011 and Lactobacillus helveticus R0052 maintains beneficial gut flora during antibiotic use and helps restore beneficial gut flora after antibiotic use. Lacidofil probiotics relieve diarrhoea.\u003c\/li\u003e\n\u003cli\u003eProbiotics help maintain digestive system health and function. The clinically trialled Lacidofil probiotic strains in PepZin Pro help relieve the symptoms of medically diagnosed irritable bowel syndrome including a reduction in abdominal pain.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBioCeuticals PepZin Pro AUST L 319072\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe naturopathic medicines listed below are suggestions that may be used as a substitute if the naturopathic medicine you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca rel=\"noopener\" title=\"BioCeuticals Clinical IM Repair 150g 10% off RRP | HealthMasters BioCeuticals\" href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-clinical-im-repair-150g\" target=\"_blank\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-clinical-im-repair-150g\"\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003eBioCeuticals Clinical IM Repair 150g or 300g\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca rel=\"noopener\" title=\"BioCeuticals MultiGest Enzymes 90cap 10% off RRP | HealthMasters BioCeuticals\" href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-multigest-enzymes-90-caps\" target=\"_blank\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-multigest-enzymes-90-caps\"\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003eBioCeuticals MultiGest Enzymes 90caps\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca rel=\"noopener\" title=\"Metagenics Gut InflamX 10% off RRP | HealthMasters Metagenics\" href=\"https:\/\/shop.healthmasters.com.au\/products\/metagenics-gut-inflamx-60-caps\" target=\"_blank\"\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003eMetagenics Gut InflamX\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate naturopathic medicine, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" title=\"Contact HealthMasters For Assistance\" target=\"_blank\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eAdults:\u003c\/strong\u003e For symptoms of mild gastritis: Take 3-6 capsules daily. During and after antibiotic use: Take 1-3 capsules daily.\u003c\/p\u003e\n\u003cp\u003eTake as above or as directed by your health professional.\u003c\/p\u003e\n\u003ch5\u003eFeatures\u003c\/h5\u003e\n\u003ch2\u003eFeatures: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eContains Polaprezinc (zinc carnosine) PepZinGI a highly bioavailable chelated form of zinc.\u003c\/li\u003e\n\u003cli\u003ePolaprezinc (zinc carnosine) PepZinGI helps relieve symptoms of mild gastritis including gastrointestinal pain, nausea, abdominal distention and heartburn.\u003c\/li\u003e\n\u003cli\u003eFormulated with Lacidofil which is a clinically trialled probiotic combination of Lactobacillus helveticus Rosell-52 (R0052) and Lactobacillus rhamnosus Rosell-11 (R0011).\u003c\/li\u003e\n\u003cli\u003eLacidofil relieves symptoms of medically diagnosed irritable bowel syndrome including a reduction in abdominal pain.\u003c\/li\u003e\n\u003cli\u003eLactobacillus rhamnosus supports beneficial gut flora during antibiotic use and restores beneficial gut flora after antibiotic use.\u003c\/li\u003e\n\u003cli\u003eZinc supports wound healing.\u003c\/li\u003e\n\u003cli\u003eVegan friendly.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003ctable width='100%\"'\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach capsule contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePolaprezinc (zinc carnosine) - PepZin GI\u003c\/td\u003e\n\u003ctd\u003e25mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ezinc\u003c\/td\u003e\n\u003ctd\u003e5.56mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. to carnosine\u003c\/td\u003e\n\u003ctd\u003e19.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus rhamnosus R0011 (Lacidofil)\u003c\/td\u003e\n\u003ctd\u003e3.8 billion CFU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus helveticus R0052 (Lacidofil)\u003c\/td\u003e\n\u003ctd\u003e200 million CFU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eGastritis\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eWith roughly 40% of the Australian population over 60 years old infected with a bacteria which can cause gastritis28-29, it is a common clinical presentation. Gastritis is an inflammation of the stomach lining.1,8 Common causes of gastritis include non-steroidal anti-inflammatory medication (NSAIDs), alcohol and bacterial infection.8 Zinc carnosine helps relieve the symptoms of mild gastritis including gastrointestinal pain, nausea, bloating and heartburn.\u003c\/p\u003e\n\u003ch3\u003ePolaprezinc (zinc carnosine)\u003c\/h3\u003e\n\u003cp\u003ePepZin Pro contains PepZinGI a compound which was developed in 1983 and is a novel chelated crystalline compound combining zinc and L-carnosine (N-beta-alanyl-L-histidine).15 The healing properties of zinc are well established and the use of zinc in combination with carnosine is innovative, due to the synergistic effects and beneficial properties as a combination.4 Combining both zinc and L-carnosine into a molecule, called polaprezinc, has been shown in rats to have a greater effect than each individual nutrient, even when taken together.16-17 For over 20 years, zinc carnosine has been used in Japan for promoting healing of gastric mucosa. In vivo and in vitro studies have shown that zinc carnosine has a particular affinity with the digestive tract.9-14 This is due to zinc carnosine having the ability to be broken down slowly in the digestive juices, allowing it to stay in contact with the gastrointestinal tissues for longer.4 Animal studies show that this extended exposure enables zinc carnosine to aid in wound healing and to exert its beneficial health effects on this area.4,16-17\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eWound healing\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eZinc assists in wound healing. In vivo and in vitro studies suggest that zinc carnosine prevents gastric mucosal injury.2 The hypothesis behind this is attributed to several mechanisms, including the wound healing properties of zinc. Research on healthy humans alongside in vivo and in vitro models of gut injury and repair has shown that when zinc carnosine was given alongside a medication, there was no increase in gut permeability when compared to taking the medication alone. When the medicine was administered alone, it caused a three-fold increase in gut permeability after five days of treatment suggesting stabilisation of the gut mucosa.9 L\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eLacidofil probiotic blend\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eThe beneficial effects of probiotic supplementation are known to maintain beneficial intestinal flora and re-establish it when it is disturbed.24-26 This includes the Lactobacillus rhamnosus strain as it maintains beneficial gut flora during antibiotic use and restores beneficial gut flora after antibiotic use.19, 22 Lacidofil is a probiotic blend consisting of Lactobacillus rhamnosus (L. rhamnosus) Rosell-11, R0011 and Lactobacillus helveticus (L. helveticus) Rosell-52, R0052. Both of these strains have full genome sequencing and can survive in the gastrointestinal tract as they are unaffected by bile and gastric acidity.7 Lacidofil also relieves diarrhoea.22-23\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMineral supplements should not replace a balanced diet.\u003c\/li\u003e\n\u003cli\u003eIf symptoms persist or worsen speak to your medical practitioner.\u003c\/li\u003e\n\u003cli\u003eContains zinc which may be dangerous if taken in large amounts or for a long period.\u003c\/li\u003e\n\u003cli\u003eContains soy.\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children.\u003c\/li\u003e\n\u003cli\u003eDo not use if seal on cap is broken.\u003c\/li\u003e\n\u003cli\u003eStore below 25°C. Shelf stable.\u003c\/li\u003e\n\u003cli\u003eIf you have any pre-existing conditions, are on any medications, always talk to your health professional before use.\u003c\/li\u003e\n\u003cli\u003eSome products should be ceased at least two weeks before any elective surgery, please confirm with your health professional.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003cp\u003e[1] Miyoshi A, Matsuo H, Miwa T, et al. Clinical Evaluation of Z-103 in the Treatment of Gastritis Ref. 30. A multicentre double-blind dose finding study. Jpn Pharmacol Ther 1997;25(5):1403-1442\u003c\/p\u003e\n\u003cp\u003e[2] Fuji Y, Matsura T, Kai M, et al. Protection by Polaprezinc, an Anti-ulcer Drug, Against Indomethacin-Induced Apoptosis in Rat Gastric Mucosal Cells. Jpm. J. Pharmacol. 2000;84(1):63-70\u003c\/p\u003e\n\u003cp\u003e[3] Tan B, Luo HQ, Xu H, et al. Polaprezinc combined with clarithromycin-based triple therapy for Helicobacter pylori-associated gastritis: A prospective, multicenter, randomized clinical trial. PLoS ONE 12(4): e0175625.\u003c\/p\u003e\n\u003cp\u003e[4] Matsukura T, Tanaka H. Applicability of Zinc Complex of L-Carnosine for Med-ical Use. Biochemistry (Moscow), Vol 65, No. 7, 2000, pp. 817-823\u003c\/p\u003e\n\u003cp\u003e[5] Simadibrata M, Ndraha S, Tedjasaputra R, et al. Revealing the effect of probiotic combination: Lactobacillus rhamnosus and Lactobacillus acidophilus (Lacidofil) on acute diarrhea in adult patients. Journal of Clinical Medicine and Research 2013;5:(2):23-28\u003c\/p\u003e\n\u003cp\u003e[6] Song H. et al. Effect of Probiotic Lactobacillus (Lacidofil Cap) for the Prevention of Antibiotic-associated Diarrhea: A Prospective, Randomized, Double-blind, Mul-ticenter Study. J Korean Med Sci. 2010;25(12):1784–1791.\u003c\/p\u003e\n\u003cp\u003e[7] Lacidofil Unique combination. Twenty-six clinical studies. Lallemand brochure.\u003c\/p\u003e\n\u003cp\u003e[8] Better Health Channel. Gastritis. Viewed 16th July 2019 https:\/\/www.betterhealth.vic.gov.au\/health\/ConditionsAndTreatments\/gastritis\u003c\/p\u003e\n\u003cp\u003e[9] Mahmood A, Fitzgerald AJ, Marchbank T, et al. Zinc carnosine, a health food sup-plement that stabilises small bowel integrity and stimulates gut repair processes. Gut 2007;56(2):168-175\u003c\/p\u003e\n\u003cp\u003e[10] Shimada T, Watanabe N, Ohtsuka Y, et al. Polaprezinc down-regulates proinflamma-tory cytokine-induced nuclear factor-kappB activation and interleukin-8 expression in gastric epithelial cells. J Pharmacol Exp Ther 1999;291(1):345-352.\u003c\/p\u003e\n\u003cp\u003e[11] Hiraishi H, Sasai T, Oinuma T, et al. Polaprezinc protects gastric mucosal cells from noxious agents through antioxidant properties in vitro. Aliment Pharmacol Ther 1999;13(2):261.\u003c\/p\u003e\n\u003cp\u003e[12] Handa O, Yoshida N, Tanaka Y, et al. Inhibitory effect of polaprezinc on the inflamma-tory response to Helicobacter pylori. Can J Gastroenterol 2002;16(11):785-789.\u003c\/p\u003e\n\u003cp\u003e[13] Cho CH, Luk CT, Ogle CW. The membrane-stabilizing action of zinc carnosine (Z-103) in stress-induced gastric ulceration in rats. Life Sci 1991;49(23):PL189-194.\u003c\/p\u003e\n\u003cp\u003e[14] Ueki S, Seiki M, Yoneta T, et al. Effect of Z-103 on compound 48\/80-induced gastric lesions in rats. Scand J Gastroenterol Suppl 1989;162:202-205.\u003c\/p\u003e\n\u003cp\u003e[15] PepZinGI. Scientific Literature for PepZinGI. Viewed 16th July 2019 https:\/\/www.pepzingi.com\/health_claims.php\u003c\/p\u003e\n\u003cp\u003e[16] Opoka W, Adamek D, Plonka M, et al. Importance of luminal and mucosal zinc in the mechanism of experimental gastric ulcer healing. J Physiology Pharmacol 2010;61(5):581-591.\u003c\/p\u003e\n\u003cp\u003e[17] Furuta S, Toyama S, Miwa M, et al. Residence time of polaprezinc (zinc L-carnosine complex) in the rat stomach and adhesiveness to ulcerous sites. Jpn J Pharmacol 1995;67(4):271-278.\u003c\/p\u003e\n\u003cp\u003e[18] Drake VJ. Zinc. Micronutrient information center, Linus Pauling Institute 2013. Viewed 10 June 2014, http:\/\/lpi.oregonstate.edu\/infocenter\/minerals\/zinc\/\u003c\/p\u003e\n\u003cp\u003e[19] Braun L, Cohen M. Herbs \u0026amp; Natural Supplements: An evidence-based guide, Volume 2, 4th ed. Sydney: Churchill Livingstone Elsevier, 2015.\u003c\/p\u003e\n\u003cp\u003e[20] Therapeutic Research Center. Natural Medicines Database 2019. Professional Mon-ograph, Zinc. Viewed 30 July 2019. https:\/\/naturalmedicines.therapeuticresearch.com\/databases\/food,-herbs-supplements\/professional.aspx?productid=982\u003c\/p\u003e\n\u003cp\u003e[21] Foster LM, Tompkins TA, Dahl WJ. A comprehensive post-market review of studies on a probiotic prod-uct containing Lactobacillus helveticus R0052 and Lactobacillus rhamnosus R0011. Beneficial Microbes. 2011;2(4):319-334\u003c\/p\u003e\n\u003cp\u003e[22] Evans M, Salewski RP, Christman MC, et al. Effectiveness of Lactobacillus helveticus and Lactobacillus rhamno-sus for the management of antibiotic-associated diarrhoea in healthy adults: a random-ized, double-blind, placebo-controlled trial. Br J Nutr. 2016;116(1):94-103\u003c\/p\u003e\n\u003cp\u003e[23] Simadibrata M, Ndraha S, Tedjasaputra R, et al. Revealing the effect of probiotic combination: Lactobacillus rhamnosus and Lactobacillus acidophilus (Lacidofil®) on acute diarrhea in adult patients. Journal of Clinical Medicine and Research 2013;5(2):23-28\u003c\/p\u003e\n\u003cp\u003e[24] Health Canada. Probiotics. Viewed 2nd August 2019. http:\/\/webprod.hc-sc.gc.ca\/nhpid-bdipsn\/atReq.do?atid=probio\u0026amp;lang=eng#t2fn1\u003c\/p\u003e\n\u003cp\u003e[25] Hendler, PDR for Nutritional Supplements p. 517\u003c\/p\u003e\n\u003cp\u003e[26] Linares DM, Ross P, Stanton C. Beneficial Microbes: The pharmacy in the gut. Bio-engineered. 2016;7(1):1-20\u003c\/p\u003e\n\u003cp\u003e[27] Therapeutic Research Center. Natural Medicines Database 2019. Professional Monograph, Carnosine. Viewed 9th August 2019. https:\/\/naturalmedicines.therapeuticresearch.com\/databases\/food,-herbs-supplements\/professional.aspx?productid=1038\u003c\/p\u003e\n\u003cp\u003e[28] GESA Gastroentrological Society of Australia. Helicobacter Pylori. Viewed 14th Au-gust 2019. https:\/\/www.gesa.org.au\/index.cfm\/\/resources\/patients\/helicobacter-pylori\/\u003c\/p\u003e\n\u003cp\u003e[29] dhf. Digestive Health Foundation. GESA Gastroenteological Society of Australia. In-formation about Helicobacter Pylori (H. pylori). Third edition 2010. Viewed 14th August 2019. http:\/\/cart.gesa.org.au\/membes\/files\/Consumer%20Information\/H_Pylori.pdf\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2022-10-11T16:03:51+11:00","created_at":"2020-06-13T12:47:09+10:00","vendor":"BioCeuticals","type":"BioCeuticals Naturopathic Medicines","tags":["BioCeuticals","Discontinued","Naturopathic","PB","Zinc Carnosine"],"price":4496,"price_min":4496,"price_max":4496,"available":false,"price_varies":false,"compare_at_price":4995,"compare_at_price_min":4995,"compare_at_price_max":4995,"compare_at_price_varies":false,"variants":[{"id":34611703021726,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"BiCPepZinPro60C","requires_shipping":true,"taxable":true,"featured_image":null,"available":false,"name":"BioCeuticals PepZin Pro 60 caps","public_title":null,"options":["Default Title"],"price":4496,"weight":114,"compare_at_price":4995,"inventory_quantity":0,"inventory_management":"shopify","inventory_policy":"deny","barcode":"9337896003145","requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsPepZinPro60caps10_offRRPatHealthMasters.jpg?v=1592017710","\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsPepZinPro60capspill10_offRRPatHealthMasters.jpg?v=1592017741"],"featured_image":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsPepZinPro60caps10_offRRPatHealthMasters.jpg?v=1592017710","options":["Title"],"media":[{"alt":"BioCeuticals PepZin Pro 60 caps 10% off RRP | HealthMasters","id":9521098162334,"position":1,"preview_image":{"aspect_ratio":0.76,"height":500,"width":380,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsPepZinPro60caps10_offRRPatHealthMasters.jpg?v=1592017710"},"aspect_ratio":0.76,"height":500,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsPepZinPro60caps10_offRRPatHealthMasters.jpg?v=1592017710","width":380},{"alt":"BioCeuticals PepZin Pro 60 caps pill 10% off RRP at HealthMasters","id":9521102913694,"position":2,"preview_image":{"aspect_ratio":1.556,"height":90,"width":140,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsPepZinPro60capspill10_offRRPatHealthMasters.jpg?v=1592017741"},"aspect_ratio":1.556,"height":90,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsPepZinPro60capspill10_offRRPatHealthMasters.jpg?v=1592017741","width":140}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch2\u003eBioCeuticals PepZin Pro 60 caps\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eTo Reduce and Relieve the Symptoms of Mild Gastritis and Support Gut Flora\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003eDiscontinued by the manufacturer for recommended alternatives see\u003c\/span\u003e \u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-pepzin-pro-60-caps?_pos=1\u0026amp;_psq=PepZn\u0026amp;_ss=e\u0026amp;_v=1.0#similar-products\" title=\"BioCeuticals PepZin Pro Similar Products 10% off RRP | HealthMasters BioCeuticals\" rel=\"noopener\" target=\"_blank\"\u003eSimilar Products TAB\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eAvailable In Sizes: 60 capsules\u003c\/p\u003e\n\u003cp\u003eBioCeuticals PepZin Pro Summary:\u003c\/p\u003e\n\u003cp\u003ePolaprezinc (zinc carnosine) PepZinGI a novel crystalline chelated compound consisting of L-Carnosine (N-ß-alanyl-L-histadine), is a highly bioavailable form of zinc and helps relieve symptoms of mild gastritis including gastrointestinal pain, nausea, abdominal distention and heartburn.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSupplementation with probiotics, including Lacidofil, Lactobacillus rhamnosus R0011 and Lactobacillus helveticus R0052 maintains beneficial gut flora during antibiotic use and helps restore beneficial gut flora after antibiotic use. Lacidofil probiotics relieve diarrhoea.\u003c\/li\u003e\n\u003cli\u003eProbiotics help maintain digestive system health and function. The clinically trialled Lacidofil probiotic strains in PepZin Pro help relieve the symptoms of medically diagnosed irritable bowel syndrome including a reduction in abdominal pain.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBioCeuticals PepZin Pro AUST L 319072\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe naturopathic medicines listed below are suggestions that may be used as a substitute if the naturopathic medicine you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca rel=\"noopener\" title=\"BioCeuticals Clinical IM Repair 150g 10% off RRP | HealthMasters BioCeuticals\" href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-clinical-im-repair-150g\" target=\"_blank\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-clinical-im-repair-150g\"\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003eBioCeuticals Clinical IM Repair 150g or 300g\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca rel=\"noopener\" title=\"BioCeuticals MultiGest Enzymes 90cap 10% off RRP | HealthMasters BioCeuticals\" href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-multigest-enzymes-90-caps\" target=\"_blank\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-multigest-enzymes-90-caps\"\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003eBioCeuticals MultiGest Enzymes 90caps\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca rel=\"noopener\" title=\"Metagenics Gut InflamX 10% off RRP | HealthMasters Metagenics\" href=\"https:\/\/shop.healthmasters.com.au\/products\/metagenics-gut-inflamx-60-caps\" target=\"_blank\"\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003eMetagenics Gut InflamX\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate naturopathic medicine, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" title=\"Contact HealthMasters For Assistance\" target=\"_blank\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eAdults:\u003c\/strong\u003e For symptoms of mild gastritis: Take 3-6 capsules daily. During and after antibiotic use: Take 1-3 capsules daily.\u003c\/p\u003e\n\u003cp\u003eTake as above or as directed by your health professional.\u003c\/p\u003e\n\u003ch5\u003eFeatures\u003c\/h5\u003e\n\u003ch2\u003eFeatures: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eContains Polaprezinc (zinc carnosine) PepZinGI a highly bioavailable chelated form of zinc.\u003c\/li\u003e\n\u003cli\u003ePolaprezinc (zinc carnosine) PepZinGI helps relieve symptoms of mild gastritis including gastrointestinal pain, nausea, abdominal distention and heartburn.\u003c\/li\u003e\n\u003cli\u003eFormulated with Lacidofil which is a clinically trialled probiotic combination of Lactobacillus helveticus Rosell-52 (R0052) and Lactobacillus rhamnosus Rosell-11 (R0011).\u003c\/li\u003e\n\u003cli\u003eLacidofil relieves symptoms of medically diagnosed irritable bowel syndrome including a reduction in abdominal pain.\u003c\/li\u003e\n\u003cli\u003eLactobacillus rhamnosus supports beneficial gut flora during antibiotic use and restores beneficial gut flora after antibiotic use.\u003c\/li\u003e\n\u003cli\u003eZinc supports wound healing.\u003c\/li\u003e\n\u003cli\u003eVegan friendly.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003ctable width='100%\"'\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach capsule contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePolaprezinc (zinc carnosine) - PepZin GI\u003c\/td\u003e\n\u003ctd\u003e25mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ezinc\u003c\/td\u003e\n\u003ctd\u003e5.56mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. to carnosine\u003c\/td\u003e\n\u003ctd\u003e19.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus rhamnosus R0011 (Lacidofil)\u003c\/td\u003e\n\u003ctd\u003e3.8 billion CFU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLactobacillus helveticus R0052 (Lacidofil)\u003c\/td\u003e\n\u003ctd\u003e200 million CFU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eGastritis\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eWith roughly 40% of the Australian population over 60 years old infected with a bacteria which can cause gastritis28-29, it is a common clinical presentation. Gastritis is an inflammation of the stomach lining.1,8 Common causes of gastritis include non-steroidal anti-inflammatory medication (NSAIDs), alcohol and bacterial infection.8 Zinc carnosine helps relieve the symptoms of mild gastritis including gastrointestinal pain, nausea, bloating and heartburn.\u003c\/p\u003e\n\u003ch3\u003ePolaprezinc (zinc carnosine)\u003c\/h3\u003e\n\u003cp\u003ePepZin Pro contains PepZinGI a compound which was developed in 1983 and is a novel chelated crystalline compound combining zinc and L-carnosine (N-beta-alanyl-L-histidine).15 The healing properties of zinc are well established and the use of zinc in combination with carnosine is innovative, due to the synergistic effects and beneficial properties as a combination.4 Combining both zinc and L-carnosine into a molecule, called polaprezinc, has been shown in rats to have a greater effect than each individual nutrient, even when taken together.16-17 For over 20 years, zinc carnosine has been used in Japan for promoting healing of gastric mucosa. In vivo and in vitro studies have shown that zinc carnosine has a particular affinity with the digestive tract.9-14 This is due to zinc carnosine having the ability to be broken down slowly in the digestive juices, allowing it to stay in contact with the gastrointestinal tissues for longer.4 Animal studies show that this extended exposure enables zinc carnosine to aid in wound healing and to exert its beneficial health effects on this area.4,16-17\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eWound healing\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eZinc assists in wound healing. In vivo and in vitro studies suggest that zinc carnosine prevents gastric mucosal injury.2 The hypothesis behind this is attributed to several mechanisms, including the wound healing properties of zinc. Research on healthy humans alongside in vivo and in vitro models of gut injury and repair has shown that when zinc carnosine was given alongside a medication, there was no increase in gut permeability when compared to taking the medication alone. When the medicine was administered alone, it caused a three-fold increase in gut permeability after five days of treatment suggesting stabilisation of the gut mucosa.9 L\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eLacidofil probiotic blend\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eThe beneficial effects of probiotic supplementation are known to maintain beneficial intestinal flora and re-establish it when it is disturbed.24-26 This includes the Lactobacillus rhamnosus strain as it maintains beneficial gut flora during antibiotic use and restores beneficial gut flora after antibiotic use.19, 22 Lacidofil is a probiotic blend consisting of Lactobacillus rhamnosus (L. rhamnosus) Rosell-11, R0011 and Lactobacillus helveticus (L. helveticus) Rosell-52, R0052. Both of these strains have full genome sequencing and can survive in the gastrointestinal tract as they are unaffected by bile and gastric acidity.7 Lacidofil also relieves diarrhoea.22-23\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMineral supplements should not replace a balanced diet.\u003c\/li\u003e\n\u003cli\u003eIf symptoms persist or worsen speak to your medical practitioner.\u003c\/li\u003e\n\u003cli\u003eContains zinc which may be dangerous if taken in large amounts or for a long period.\u003c\/li\u003e\n\u003cli\u003eContains soy.\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children.\u003c\/li\u003e\n\u003cli\u003eDo not use if seal on cap is broken.\u003c\/li\u003e\n\u003cli\u003eStore below 25°C. Shelf stable.\u003c\/li\u003e\n\u003cli\u003eIf you have any pre-existing conditions, are on any medications, always talk to your health professional before use.\u003c\/li\u003e\n\u003cli\u003eSome products should be ceased at least two weeks before any elective surgery, please confirm with your health professional.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: BioCeuticals PepZin Pro\u003c\/h2\u003e\n\u003cp\u003e[1] Miyoshi A, Matsuo H, Miwa T, et al. Clinical Evaluation of Z-103 in the Treatment of Gastritis Ref. 30. A multicentre double-blind dose finding study. Jpn Pharmacol Ther 1997;25(5):1403-1442\u003c\/p\u003e\n\u003cp\u003e[2] Fuji Y, Matsura T, Kai M, et al. Protection by Polaprezinc, an Anti-ulcer Drug, Against Indomethacin-Induced Apoptosis in Rat Gastric Mucosal Cells. Jpm. J. Pharmacol. 2000;84(1):63-70\u003c\/p\u003e\n\u003cp\u003e[3] Tan B, Luo HQ, Xu H, et al. Polaprezinc combined with clarithromycin-based triple therapy for Helicobacter pylori-associated gastritis: A prospective, multicenter, randomized clinical trial. PLoS ONE 12(4): e0175625.\u003c\/p\u003e\n\u003cp\u003e[4] Matsukura T, Tanaka H. Applicability of Zinc Complex of L-Carnosine for Med-ical Use. Biochemistry (Moscow), Vol 65, No. 7, 2000, pp. 817-823\u003c\/p\u003e\n\u003cp\u003e[5] Simadibrata M, Ndraha S, Tedjasaputra R, et al. Revealing the effect of probiotic combination: Lactobacillus rhamnosus and Lactobacillus acidophilus (Lacidofil) on acute diarrhea in adult patients. Journal of Clinical Medicine and Research 2013;5:(2):23-28\u003c\/p\u003e\n\u003cp\u003e[6] Song H. et al. Effect of Probiotic Lactobacillus (Lacidofil Cap) for the Prevention of Antibiotic-associated Diarrhea: A Prospective, Randomized, Double-blind, Mul-ticenter Study. J Korean Med Sci. 2010;25(12):1784–1791.\u003c\/p\u003e\n\u003cp\u003e[7] Lacidofil Unique combination. Twenty-six clinical studies. Lallemand brochure.\u003c\/p\u003e\n\u003cp\u003e[8] Better Health Channel. Gastritis. Viewed 16th July 2019 https:\/\/www.betterhealth.vic.gov.au\/health\/ConditionsAndTreatments\/gastritis\u003c\/p\u003e\n\u003cp\u003e[9] Mahmood A, Fitzgerald AJ, Marchbank T, et al. Zinc carnosine, a health food sup-plement that stabilises small bowel integrity and stimulates gut repair processes. Gut 2007;56(2):168-175\u003c\/p\u003e\n\u003cp\u003e[10] Shimada T, Watanabe N, Ohtsuka Y, et al. Polaprezinc down-regulates proinflamma-tory cytokine-induced nuclear factor-kappB activation and interleukin-8 expression in gastric epithelial cells. J Pharmacol Exp Ther 1999;291(1):345-352.\u003c\/p\u003e\n\u003cp\u003e[11] Hiraishi H, Sasai T, Oinuma T, et al. Polaprezinc protects gastric mucosal cells from noxious agents through antioxidant properties in vitro. Aliment Pharmacol Ther 1999;13(2):261.\u003c\/p\u003e\n\u003cp\u003e[12] Handa O, Yoshida N, Tanaka Y, et al. Inhibitory effect of polaprezinc on the inflamma-tory response to Helicobacter pylori. Can J Gastroenterol 2002;16(11):785-789.\u003c\/p\u003e\n\u003cp\u003e[13] Cho CH, Luk CT, Ogle CW. The membrane-stabilizing action of zinc carnosine (Z-103) in stress-induced gastric ulceration in rats. Life Sci 1991;49(23):PL189-194.\u003c\/p\u003e\n\u003cp\u003e[14] Ueki S, Seiki M, Yoneta T, et al. Effect of Z-103 on compound 48\/80-induced gastric lesions in rats. Scand J Gastroenterol Suppl 1989;162:202-205.\u003c\/p\u003e\n\u003cp\u003e[15] PepZinGI. Scientific Literature for PepZinGI. Viewed 16th July 2019 https:\/\/www.pepzingi.com\/health_claims.php\u003c\/p\u003e\n\u003cp\u003e[16] Opoka W, Adamek D, Plonka M, et al. Importance of luminal and mucosal zinc in the mechanism of experimental gastric ulcer healing. J Physiology Pharmacol 2010;61(5):581-591.\u003c\/p\u003e\n\u003cp\u003e[17] Furuta S, Toyama S, Miwa M, et al. Residence time of polaprezinc (zinc L-carnosine complex) in the rat stomach and adhesiveness to ulcerous sites. Jpn J Pharmacol 1995;67(4):271-278.\u003c\/p\u003e\n\u003cp\u003e[18] Drake VJ. Zinc. Micronutrient information center, Linus Pauling Institute 2013. Viewed 10 June 2014, http:\/\/lpi.oregonstate.edu\/infocenter\/minerals\/zinc\/\u003c\/p\u003e\n\u003cp\u003e[19] Braun L, Cohen M. Herbs \u0026amp; Natural Supplements: An evidence-based guide, Volume 2, 4th ed. Sydney: Churchill Livingstone Elsevier, 2015.\u003c\/p\u003e\n\u003cp\u003e[20] Therapeutic Research Center. Natural Medicines Database 2019. Professional Mon-ograph, Zinc. Viewed 30 July 2019. https:\/\/naturalmedicines.therapeuticresearch.com\/databases\/food,-herbs-supplements\/professional.aspx?productid=982\u003c\/p\u003e\n\u003cp\u003e[21] Foster LM, Tompkins TA, Dahl WJ. A comprehensive post-market review of studies on a probiotic prod-uct containing Lactobacillus helveticus R0052 and Lactobacillus rhamnosus R0011. Beneficial Microbes. 2011;2(4):319-334\u003c\/p\u003e\n\u003cp\u003e[22] Evans M, Salewski RP, Christman MC, et al. Effectiveness of Lactobacillus helveticus and Lactobacillus rhamno-sus for the management of antibiotic-associated diarrhoea in healthy adults: a random-ized, double-blind, placebo-controlled trial. Br J Nutr. 2016;116(1):94-103\u003c\/p\u003e\n\u003cp\u003e[23] Simadibrata M, Ndraha S, Tedjasaputra R, et al. Revealing the effect of probiotic combination: Lactobacillus rhamnosus and Lactobacillus acidophilus (Lacidofil®) on acute diarrhea in adult patients. Journal of Clinical Medicine and Research 2013;5(2):23-28\u003c\/p\u003e\n\u003cp\u003e[24] Health Canada. Probiotics. Viewed 2nd August 2019. http:\/\/webprod.hc-sc.gc.ca\/nhpid-bdipsn\/atReq.do?atid=probio\u0026amp;lang=eng#t2fn1\u003c\/p\u003e\n\u003cp\u003e[25] Hendler, PDR for Nutritional Supplements p. 517\u003c\/p\u003e\n\u003cp\u003e[26] Linares DM, Ross P, Stanton C. Beneficial Microbes: The pharmacy in the gut. Bio-engineered. 2016;7(1):1-20\u003c\/p\u003e\n\u003cp\u003e[27] Therapeutic Research Center. Natural Medicines Database 2019. Professional Monograph, Carnosine. Viewed 9th August 2019. https:\/\/naturalmedicines.therapeuticresearch.com\/databases\/food,-herbs-supplements\/professional.aspx?productid=1038\u003c\/p\u003e\n\u003cp\u003e[28] GESA Gastroentrological Society of Australia. Helicobacter Pylori. Viewed 14th Au-gust 2019. https:\/\/www.gesa.org.au\/index.cfm\/\/resources\/patients\/helicobacter-pylori\/\u003c\/p\u003e\n\u003cp\u003e[29] dhf. Digestive Health Foundation. GESA Gastroenteological Society of Australia. In-formation about Helicobacter Pylori (H. pylori). Third edition 2010. Viewed 14th August 2019. http:\/\/cart.gesa.org.au\/membes\/files\/Consumer%20Information\/H_Pylori.pdf\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}