{"id":5735223132318,"title":"Orthoplex SaffroMind 60c","handle":"orthoplex-white-white-saffromind-60c","description":"\u003ch2\u003eOrthoplex White SaffroMind 60c\u003c\/h2\u003e\n\u003cp\u003eOrthoplex White SaffroMind addresses mood balance, mild anxiety and sleeplessness with a targeted, premium herbal and essential oil solution that may be suitable to prescribe alongside common pharmaceutical medications.\u003c\/p\u003e\n\u003cp\u003e10% off RRP at HealthMasters\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind (formerly called NeuroCare) is part of the Orthoplex White Range\u003c\/p\u003e\n\u003cp\u003ePack Size: 60 Capsules\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind Allergen Advice: Gluten Free, Egg Free, Dairy Free, Soy Protein Free\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind is Vegan, Vegetarian\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind AUST L 336055\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe naturopathic medicines listed below are suggestions that may be used as a substitute if the naturopathic medicines you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/saffron\" target=\"_blank\" title=\"Similar Products Containing Saffron | HealthMasters Saffron\" rel=\"noopener noreferrer\"\u003eSimilar Products Containing Saffron\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate naturopathic medicines, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" title=\"Contact HealthMasters For Assistance\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eProduct Summary\u003c\/h5\u003e\n\u003ch2\u003eProduct Summary: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eOrthoplex White SaffroMind contains an organic French saffron extract made exclusively from 100% fresh red stigmas. Developed in a patented encapsulation technology, independent testing has verified its rich concentration of bioactive compounds including safranal and crocins.\u003c\/p\u003e\n\u003cp\u003eCombined with lavender essential oil, containing scientifically validated levels of linalool and linalyl acetate, these verified levels of active constituents link directly to the scientific literature addressing mood balance and mild anxiety.\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind also contains our industry-first turmeric delivering more than 70 bioactive turmeric molecules.\u003c\/p\u003e\n\u003cp\u003eContains:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOrganic French saffron extract delivering scientifically validated safranal, crocins and safromotivines\u003c\/li\u003e\n\u003cli\u003eSteam distilled lavender essential oil with verified levels of linalool and linalyl acetate\u003c\/li\u003e\n\u003cli\u003eSuitable alongside common mood-regulating pharmaceutical medications\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe saffron in Orthoplex White SaffroMind has been third party tested at one of Australia’s most respected phytochemical laboratories; while the lavender essential oil has verified levels of active constituents. Orthoplex White SaffroMind exhibits crocin and safranal in saffron; and linalool and linalyl acetate in lavender essential oil at levels that are consistent with clinical research finding positive effects on mood balance and mild anxiety.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFig. 1. Independent third-party testing at Australia’smost respected phytochemical laboratory reports:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_1_600x600.jpg?v=1600750881\" alt=\"Orthoplex White NeuroCare 60c 10% off RRP at HealthMasters Orthoplex White Figure 1\"\u003e\u003c\/p\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eAdult Dose\u003c\/p\u003e\n\u003cp\u003eTake 1-2 capsules daily or as recommended by your registered healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eIndications\u003c\/h5\u003e\n\u003ch2\u003eIndications: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy emotional\/mood balance\u003c\/li\u003e\n\u003cli\u003eRelieves symptoms of mild anxiety and stress\u003c\/li\u003e\n\u003cli\u003eTraditionally used in Western herbal medicine to reduce sleeplessness\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eSupports Healthy Emotional\/Mood Balance\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eMost patients with low mood suffer from impaired sleep, with about 80 percent suffering from insomnia1 and around half also experiencing nervousness or tension.2 Not only do natural medicine practitioners need a solution that covers all of these symptoms, they must navigate medically prescribed treatments. Combined saffron, lavender and turmeric have been found to do this.\u003c\/p\u003e\n\u003cp\u003eA systematic review and meta-analysis of saffron found that a daily dose of 30mg extract had a large and positive effect on those experiencing issues with both emotional balance and nervousness.3 A systematic review that included six studies found that a dose of 30mg\/day resulted in statistically significant improvements in mood symptoms after the first week, and continued for the rest of the trial (six to eight weeks).4 This effect was compared to placebo and medically prescribed treatments.4\u003c\/p\u003e\n\u003cp\u003eIt is suggested that crocin and safranal in saffron inhibit the reuptake of dopamine and norepinephrine, and serotonin; they also possess antioxidant and anti-inflammatory properties, and are able to modulate Brain Derived Neurotrophic Factor (BDNF) expression and the hypothalamus-pituitary-adrenal (HPA) axis.3\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFig. 2. Effect of 30mg saffron and placebo on mood as measured on a validated mood scale\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_2_796a4a54-5f54-4635-9060-d49e5e26a754_600x600.jpg?v=1600753258\" alt=\"Orthoplex White NeuroCare 60c 10% off RRP at HealthMasters Orthoplex White Figure 2\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_2_796a4a54-5f54-4635-9060-d49e5e26a754_600x600.jpg?v=1600753258\"\u003e\u003c\/p\u003e\n\u003cp\u003eA 2019 meta-analysis which included nine studies found curcumin had a significant positive effect on those with mild mood imbalance at baseline.6 Curcumin is involved in serotonin and dopamine release, the inhibition of the enzyme monoamine oxidase (MAO) which plays a role in the metabolism of neurotransmitters and detoxifying endogenous and exogenous amines, the regulation of the HPA axis and increasing levels of BDNF.6 Its most studied mechanisms relate to its antioxidant and anti-inflammatory properties. For example, curcumin suppresses the transcription signalling pathways of nuclear factor kappa β, essential in the production of proinflammatory cytokines; and curcuminoids reduce C-reactive protein levels.6\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eRelieves Symptoms of Mild Anxiety and Stress\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eThe two primary terpenoid constituents of lavender essential oil, linalool and linalyl acetate, may reduce restlessness, in combination via inhibition of voltage-gated calcium channels, reduction of 5HT1A receptor activity, and increased parasympathetic tone.7\u003c\/p\u003e\n\u003cp\u003eOne study used a lavender essential oil with 36.8% linalool and 34.2% linalyl acetate, administered at either 80mg or 160mg per day, a medication or placebo for 10 weeks. Sixty per cent of those taking the higher dose of lavender experienced at least a halving of the Hamilton Anxiety Scale (HAMA) at study end. Improvements were seen after 4 weeks.8 This was compared to 51% of those taking 80mg daily; 34% taking medication and 38% of those taking placebo.8 The lower dose resulted in improvements after 6 weeks of supplementation.8 Lavender also had a significant effect on mood balance.8\u003c\/p\u003e\n\u003cp\u003eIn a meta-analysis, saffron had a large positive effect on symptoms of anxiety.3 Saffron lowers the HPA response to stress.4 Safranal and crocin prevented elevations in plasma corticosterone levels in animal models of stress.4\u003c\/p\u003e\n\u003cp\u003eCurcumin was also found to have a positive effect on anxiety symptoms as measured by validated tools including the Hamilton Anxiety Rating Scale.6 Its ability to inhibit MAO leading to reduced serotonin turnover is believed to be one of the mechanisms involved in reducing these symptoms.6\u003c\/p\u003e\n\u003cp\u003eFig. 3. Responder and remission rates for lavender supplementation versus placebo\u003c\/p\u003e\n\u003cp\u003e \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_3_67329cb5-9309-4dba-a4d3-0ca88c7e9d62_600x600.jpg?v=1600753388\" alt=\"Orthoplex White NeuroCare 60c 10% off RRP at HealthMasters Orthoplex White Figure 3\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_3_67329cb5-9309-4dba-a4d3-0ca88c7e9d62_600x600.jpg?v=1600753388\"\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eReduces Sleeplessness\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eIn traditional Western herbal medicine lavender oil is prescribed for sleeplessness. Patients with symptoms such as agitation or restlessness and sleep disturbance received 80mg of lavender essential oil with 36.8% linalool and 34.2% linalyl acetate for 10 weeks, or placebo – there was a 44.7% reduction in the Pittsburgh Sleep Quality Index (PSQI) compared to 30.9% in those taking placebo.9\u003c\/p\u003e\n\u003ch5\u003eingredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach Capsule contains\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCrocus sativus stigma (Dry Herb Equiv) Saffron\u003c\/td\u003e\n\u003ctd\u003e75.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurcuma longa rhizome (Dry Herb Equiv) Turmeric\u003c\/td\u003e\n\u003ctd\u003e7.81g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Curcuminoids\u003c\/td\u003e\n\u003ctd\u003e118.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLavender oil\u003c\/td\u003e\n\u003ctd\u003e80.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eMicrocrystalline cellulose, colloidal anhydrous silica, magnesium stearate, vegetable capsule (Vcaps®)*. *Incidental excipients associated with the manufacture of Vcaps: disodium edetate, gellan gum, hypromellose, potable water and potassium acetate.\u003c\/p\u003e\n\u003ch5\u003eAllergen Advice\u003c\/h5\u003e\n\u003ch2\u003eAllergen Advice: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eGluten Free, Egg Free, Dairy Free, Soy Protein Free, Vegan, Vegetarian\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eStore below 30°C in a cool, dry place away from direct sunlight.\u003c\/p\u003e\n\u003ch5\u003eWarning\u003c\/h5\u003e\n\u003ch2\u003eWarning: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eIf symptoms persist, seek the advice of a healthcare professional.\u003c\/p\u003e\n\u003ch5\u003ePregnancy \u0026amp; Lactation\u003c\/h5\u003e\n\u003ch2\u003ePregnancy \u0026amp; Lactation: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003ePregnancy not advised. Lactation contact HealthMasters email: reception@healthmasters.com.au\u003c\/p\u003e\n\u003ch5\u003eOrthoplex White\u003c\/h5\u003e\n\u003ch2\u003eOrthoplex White\u003c\/h2\u003e\n\u003cp\u003eOrthoplex White Label is a range for clinical practitioners, developed for the increasing complexity of ailments presenting in clinic. To purchase products in the Orthoplex White Label range, patients must have a consultation with a clinical practitioner. Stockists of this range are bound by a contractual set of selling standards, ensuring the products are used correctly, and contributing to the robust integrity of the industry.\u003c\/p\u003e\n\u003cp\u003e\"I am impressed with the quality and effectiveness of Orthoplex White Label products. I have prescribed Orthoplex White Label products to my patients for over 30 years. Orthoplex White Label products have assisted me in successfully helping many 1000's of patients to better health.\"\u003c\/p\u003e\n\u003cp\u003eHealthMasters Naturopath Kevin Tresize ND\u003c\/p\u003e\n\u003cp\u003eThe Orthoplex White Label range was developed by nutritional biochemist Henry Osieki. Henry is an award-winning biochemist who, after years in clinic, developed the Orthoplex label Range of Naturopathic Medicines. The Orthoplex White Label range is known for being the first to market with new formulations, incorporating the latest in clinical research.\u003c\/p\u003e\n\u003cp\u003eOrthoplex White Label formulations have always focused on providing the correct dosage for specific biochemical pathways, rather than just delivering the largest dose possible.\u003c\/p\u003e\n\u003cp\u003eOrthoplex White Label is a practitioner range of naturopathic products and should be taken according to the recommendation of a qualified practitioner.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2022-10-11T15:59:54+11:00","created_at":"2020-09-22T14:47:51+10:00","vendor":"Orthoplex","type":"Orthoplex White 10% off RRP","tags":["Naturopathic","Orthoplex White","PB","Saffron","Turmeric"],"price":6300,"price_min":6300,"price_max":6300,"available":true,"price_varies":false,"compare_at_price":7000,"compare_at_price_min":7000,"compare_at_price_max":7000,"compare_at_price_varies":false,"variants":[{"id":36269987856542,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"OpxSaffroMind60c","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Orthoplex SaffroMind 60c","public_title":null,"options":["Default Title"],"price":6300,"weight":0,"compare_at_price":7000,"inventory_quantity":19992,"inventory_management":"shopify","inventory_policy":"deny","barcode":"9319091979104","requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/Orthoplex_White_with_10_off_RRP_at_HealthMasters_583b9c6c-c595-4645-a56e-0070e55311a9.jpg?v=1600753505","\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexWhiteNeuroCare60c10_offRRPatHealthMastersOrthoplexWhite_2.jpg?v=1600753482"],"featured_image":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/Orthoplex_White_with_10_off_RRP_at_HealthMasters_583b9c6c-c595-4645-a56e-0070e55311a9.jpg?v=1600753505","options":["Title"],"media":[{"alt":"Orthoplex White SaffroMind 10% off RRP | HealtMasters Orthoplex White","id":11330533359774,"position":1,"preview_image":{"aspect_ratio":0.77,"height":1200,"width":924,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/Orthoplex_White_with_10_off_RRP_at_HealthMasters_583b9c6c-c595-4645-a56e-0070e55311a9.jpg?v=1600753505"},"aspect_ratio":0.77,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/Orthoplex_White_with_10_off_RRP_at_HealthMasters_583b9c6c-c595-4645-a56e-0070e55311a9.jpg?v=1600753505","width":924},{"alt":"Orthoplex White NeuroCare 60c 10% off RRP at HealthMasters Orthoplex White","id":11331307339934,"position":2,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexWhiteNeuroCare60c10_offRRPatHealthMastersOrthoplexWhite_2.jpg?v=1600753482"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexWhiteNeuroCare60c10_offRRPatHealthMastersOrthoplexWhite_2.jpg?v=1600753482","width":1200}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch2\u003eOrthoplex White SaffroMind 60c\u003c\/h2\u003e\n\u003cp\u003eOrthoplex White SaffroMind addresses mood balance, mild anxiety and sleeplessness with a targeted, premium herbal and essential oil solution that may be suitable to prescribe alongside common pharmaceutical medications.\u003c\/p\u003e\n\u003cp\u003e10% off RRP at HealthMasters\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind (formerly called NeuroCare) is part of the Orthoplex White Range\u003c\/p\u003e\n\u003cp\u003ePack Size: 60 Capsules\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind Allergen Advice: Gluten Free, Egg Free, Dairy Free, Soy Protein Free\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind is Vegan, Vegetarian\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind AUST L 336055\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe naturopathic medicines listed below are suggestions that may be used as a substitute if the naturopathic medicines you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/saffron\" target=\"_blank\" title=\"Similar Products Containing Saffron | HealthMasters Saffron\" rel=\"noopener noreferrer\"\u003eSimilar Products Containing Saffron\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate naturopathic medicines, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" title=\"Contact HealthMasters For Assistance\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eProduct Summary\u003c\/h5\u003e\n\u003ch2\u003eProduct Summary: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eOrthoplex White SaffroMind contains an organic French saffron extract made exclusively from 100% fresh red stigmas. Developed in a patented encapsulation technology, independent testing has verified its rich concentration of bioactive compounds including safranal and crocins.\u003c\/p\u003e\n\u003cp\u003eCombined with lavender essential oil, containing scientifically validated levels of linalool and linalyl acetate, these verified levels of active constituents link directly to the scientific literature addressing mood balance and mild anxiety.\u003c\/p\u003e\n\u003cp\u003eOrthoplex White SaffroMind also contains our industry-first turmeric delivering more than 70 bioactive turmeric molecules.\u003c\/p\u003e\n\u003cp\u003eContains:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOrganic French saffron extract delivering scientifically validated safranal, crocins and safromotivines\u003c\/li\u003e\n\u003cli\u003eSteam distilled lavender essential oil with verified levels of linalool and linalyl acetate\u003c\/li\u003e\n\u003cli\u003eSuitable alongside common mood-regulating pharmaceutical medications\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe saffron in Orthoplex White SaffroMind has been third party tested at one of Australia’s most respected phytochemical laboratories; while the lavender essential oil has verified levels of active constituents. Orthoplex White SaffroMind exhibits crocin and safranal in saffron; and linalool and linalyl acetate in lavender essential oil at levels that are consistent with clinical research finding positive effects on mood balance and mild anxiety.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFig. 1. Independent third-party testing at Australia’smost respected phytochemical laboratory reports:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_1_600x600.jpg?v=1600750881\" alt=\"Orthoplex White NeuroCare 60c 10% off RRP at HealthMasters Orthoplex White Figure 1\"\u003e\u003c\/p\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eAdult Dose\u003c\/p\u003e\n\u003cp\u003eTake 1-2 capsules daily or as recommended by your registered healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eIndications\u003c\/h5\u003e\n\u003ch2\u003eIndications: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy emotional\/mood balance\u003c\/li\u003e\n\u003cli\u003eRelieves symptoms of mild anxiety and stress\u003c\/li\u003e\n\u003cli\u003eTraditionally used in Western herbal medicine to reduce sleeplessness\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eSupports Healthy Emotional\/Mood Balance\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eMost patients with low mood suffer from impaired sleep, with about 80 percent suffering from insomnia1 and around half also experiencing nervousness or tension.2 Not only do natural medicine practitioners need a solution that covers all of these symptoms, they must navigate medically prescribed treatments. Combined saffron, lavender and turmeric have been found to do this.\u003c\/p\u003e\n\u003cp\u003eA systematic review and meta-analysis of saffron found that a daily dose of 30mg extract had a large and positive effect on those experiencing issues with both emotional balance and nervousness.3 A systematic review that included six studies found that a dose of 30mg\/day resulted in statistically significant improvements in mood symptoms after the first week, and continued for the rest of the trial (six to eight weeks).4 This effect was compared to placebo and medically prescribed treatments.4\u003c\/p\u003e\n\u003cp\u003eIt is suggested that crocin and safranal in saffron inhibit the reuptake of dopamine and norepinephrine, and serotonin; they also possess antioxidant and anti-inflammatory properties, and are able to modulate Brain Derived Neurotrophic Factor (BDNF) expression and the hypothalamus-pituitary-adrenal (HPA) axis.3\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFig. 2. Effect of 30mg saffron and placebo on mood as measured on a validated mood scale\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_2_796a4a54-5f54-4635-9060-d49e5e26a754_600x600.jpg?v=1600753258\" alt=\"Orthoplex White NeuroCare 60c 10% off RRP at HealthMasters Orthoplex White Figure 2\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_2_796a4a54-5f54-4635-9060-d49e5e26a754_600x600.jpg?v=1600753258\"\u003e\u003c\/p\u003e\n\u003cp\u003eA 2019 meta-analysis which included nine studies found curcumin had a significant positive effect on those with mild mood imbalance at baseline.6 Curcumin is involved in serotonin and dopamine release, the inhibition of the enzyme monoamine oxidase (MAO) which plays a role in the metabolism of neurotransmitters and detoxifying endogenous and exogenous amines, the regulation of the HPA axis and increasing levels of BDNF.6 Its most studied mechanisms relate to its antioxidant and anti-inflammatory properties. For example, curcumin suppresses the transcription signalling pathways of nuclear factor kappa β, essential in the production of proinflammatory cytokines; and curcuminoids reduce C-reactive protein levels.6\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eRelieves Symptoms of Mild Anxiety and Stress\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eThe two primary terpenoid constituents of lavender essential oil, linalool and linalyl acetate, may reduce restlessness, in combination via inhibition of voltage-gated calcium channels, reduction of 5HT1A receptor activity, and increased parasympathetic tone.7\u003c\/p\u003e\n\u003cp\u003eOne study used a lavender essential oil with 36.8% linalool and 34.2% linalyl acetate, administered at either 80mg or 160mg per day, a medication or placebo for 10 weeks. Sixty per cent of those taking the higher dose of lavender experienced at least a halving of the Hamilton Anxiety Scale (HAMA) at study end. Improvements were seen after 4 weeks.8 This was compared to 51% of those taking 80mg daily; 34% taking medication and 38% of those taking placebo.8 The lower dose resulted in improvements after 6 weeks of supplementation.8 Lavender also had a significant effect on mood balance.8\u003c\/p\u003e\n\u003cp\u003eIn a meta-analysis, saffron had a large positive effect on symptoms of anxiety.3 Saffron lowers the HPA response to stress.4 Safranal and crocin prevented elevations in plasma corticosterone levels in animal models of stress.4\u003c\/p\u003e\n\u003cp\u003eCurcumin was also found to have a positive effect on anxiety symptoms as measured by validated tools including the Hamilton Anxiety Rating Scale.6 Its ability to inhibit MAO leading to reduced serotonin turnover is believed to be one of the mechanisms involved in reducing these symptoms.6\u003c\/p\u003e\n\u003cp\u003eFig. 3. Responder and remission rates for lavender supplementation versus placebo\u003c\/p\u003e\n\u003cp\u003e \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_3_67329cb5-9309-4dba-a4d3-0ca88c7e9d62_600x600.jpg?v=1600753388\" alt=\"Orthoplex White NeuroCare 60c 10% off RRP at HealthMasters Orthoplex White Figure 3\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_White_NeuroCare_60c_10_off_RRP_at_HealthMasters_Orthoplex_White_Figure_3_67329cb5-9309-4dba-a4d3-0ca88c7e9d62_600x600.jpg?v=1600753388\"\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eReduces Sleeplessness\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eIn traditional Western herbal medicine lavender oil is prescribed for sleeplessness. Patients with symptoms such as agitation or restlessness and sleep disturbance received 80mg of lavender essential oil with 36.8% linalool and 34.2% linalyl acetate for 10 weeks, or placebo – there was a 44.7% reduction in the Pittsburgh Sleep Quality Index (PSQI) compared to 30.9% in those taking placebo.9\u003c\/p\u003e\n\u003ch5\u003eingredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach Capsule contains\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCrocus sativus stigma (Dry Herb Equiv) Saffron\u003c\/td\u003e\n\u003ctd\u003e75.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurcuma longa rhizome (Dry Herb Equiv) Turmeric\u003c\/td\u003e\n\u003ctd\u003e7.81g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Curcuminoids\u003c\/td\u003e\n\u003ctd\u003e118.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLavender oil\u003c\/td\u003e\n\u003ctd\u003e80.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eMicrocrystalline cellulose, colloidal anhydrous silica, magnesium stearate, vegetable capsule (Vcaps®)*. *Incidental excipients associated with the manufacture of Vcaps: disodium edetate, gellan gum, hypromellose, potable water and potassium acetate.\u003c\/p\u003e\n\u003ch5\u003eAllergen Advice\u003c\/h5\u003e\n\u003ch2\u003eAllergen Advice: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eGluten Free, Egg Free, Dairy Free, Soy Protein Free, Vegan, Vegetarian\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eStore below 30°C in a cool, dry place away from direct sunlight.\u003c\/p\u003e\n\u003ch5\u003eWarning\u003c\/h5\u003e\n\u003ch2\u003eWarning: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003eIf symptoms persist, seek the advice of a healthcare professional.\u003c\/p\u003e\n\u003ch5\u003ePregnancy \u0026amp; Lactation\u003c\/h5\u003e\n\u003ch2\u003ePregnancy \u0026amp; Lactation: Orthoplex White SaffroMind\u003c\/h2\u003e\n\u003cp\u003ePregnancy not advised. Lactation contact HealthMasters email: reception@healthmasters.com.au\u003c\/p\u003e\n\u003ch5\u003eOrthoplex White\u003c\/h5\u003e\n\u003ch2\u003eOrthoplex White\u003c\/h2\u003e\n\u003cp\u003eOrthoplex White Label is a range for clinical practitioners, developed for the increasing complexity of ailments presenting in clinic. To purchase products in the Orthoplex White Label range, patients must have a consultation with a clinical practitioner. Stockists of this range are bound by a contractual set of selling standards, ensuring the products are used correctly, and contributing to the robust integrity of the industry.\u003c\/p\u003e\n\u003cp\u003e\"I am impressed with the quality and effectiveness of Orthoplex White Label products. I have prescribed Orthoplex White Label products to my patients for over 30 years. Orthoplex White Label products have assisted me in successfully helping many 1000's of patients to better health.\"\u003c\/p\u003e\n\u003cp\u003eHealthMasters Naturopath Kevin Tresize ND\u003c\/p\u003e\n\u003cp\u003eThe Orthoplex White Label range was developed by nutritional biochemist Henry Osieki. Henry is an award-winning biochemist who, after years in clinic, developed the Orthoplex label Range of Naturopathic Medicines. The Orthoplex White Label range is known for being the first to market with new formulations, incorporating the latest in clinical research.\u003c\/p\u003e\n\u003cp\u003eOrthoplex White Label formulations have always focused on providing the correct dosage for specific biochemical pathways, rather than just delivering the largest dose possible.\u003c\/p\u003e\n\u003cp\u003eOrthoplex White Label is a practitioner range of naturopathic products and should be taken according to the recommendation of a qualified practitioner.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}