Metagenics Ultra Flora GI Regulate 150 gm

Directions

Serving suggestion:

Adults:

Add 3 metric teaspoons (5 g) to 200 mL of water and stir until dissolved. Take once daily.

Metagenics Ultra Flora GI Regulate is an easily dissolved and non-flavoured powder, making it suitable for mixing with other powdered supplements.

Note: When commencing Metagenics Ultra Flora GI Regulate it is normal to experience bloating or gas. If these symptoms are experienced reduce the dose to 1 tsp and gradually increase to 3 tsp over a period of 1-2 weeks.

Benefits

Reduction of chronic constipation and IBS symptoms: Both IBS and non IBS related constipation are commonly occurring health issues in Australia, however, non IBS related constipation is twice as common in Australia as IBS.^12,13 Lactobacillus plantarum (299v) is extensively researched and shown to reduce a range of IBS symptoms.¹⁴ Partially Hydrolysed Guar Gum (PHGG) is a selective prebiotic, used as a fuel by butyrate producing bacteria.¹⁵ A meta-analysis of seven randomised trials¹⁶ of PHGG found a reduction in chronic constipation (Figure 1) while several randomised trials,^17,18 found a significant decrease in IBS symptoms.

SIBO, methane and butyrate regulation; PHGG is fermented by large intestinal commensal bacteria increasing SCFA production particularly butyrate¹⁹ (Figure 2), as well as assisting colonic blood flow and epithelial repair.²⁰ PHGG influences gut motility, secretions and vagal modulation of contraction,²¹ and has been shown to reduce methane levels. Methane production is implicated in the reduction in 5HT (gut serotonin) levels and reduced intestinal motility.²² Excessive production of methane has been linked to gastrointestinal issues such as SIBO, chronic constipation, IBS and slow transit time.^23,24 PHGG may therefore assist in reducing severity of these conditions and symptoms. Research of PHGG has also shown other benefits, including:

• Reduced methane excretion²⁵
• Improved effectiveness of antibiotic SIBO treatment (when used with PHGG)²⁵
• Improvements in chronic constipation²⁶

Visceral hypersensitivity, abdominal pain and inflammation; Probiotics can help modulate visceral hypersensitivity (increased pain sensitivity) to reduce abdominal pain²⁷ and improve patient comfort. Both L. plantarum (299v) and PHGG have been shown to reduce abdominal pain by 50%,²⁸ which can be a key symptom driving patients to seek health advice. Gut inflammation can also contribute to pain and associated symptoms that may benefit from probiotic strains, such as L. plantarum (299v), shown to exert a modulatory effect on the inflammatory response of epithelium,²⁹ helping to improve gastrointestinal comfort and health.

Nutritional Information

Average Values given

Ingredients

Metagenics Ultra Flora GI Regulate is free from animal products, corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, soy protein, salt and FODMAPS. Free from artificial colours, flavours and preservatives.

Storage

Store at 2°C to 8°C (Refrigerate. Do not freeze).