Metagenics Inflavonoid Intensive Care 30 tablets

Directions

Adults:

For temporary relief of acute pain and joint inflammation:

Take 1 tablet every 2 hours (up to 6 tablets daily).

Benefits

Metagenics Inflavonoid Intensive Care relieves acute inflammation: The ingredients in Inflavonoid Intensive Care work at various points within the inflammatory cascade to decrease inflammation and pain associated with mild arthritis via the following mechanisms:

• Boswellia inhibits 5-lipoxygenase (5-LOX).1
• White willow bark inhibits prostaglandin synthesis by inhibiting cyclooxygenase (COX-2) mediated prostaglandin release shown in vitro.
• Ginger suppresses prostaglandin synthesis through inhibition of COX and LOX.
• Quercetin inhibits the activation of NF-ƙB demonstrated in vitro studies.

Volatile oils, naturally found in BCM-95TM turmeric, contribute to its effect. These oils exhibit anti-inflammatory activity with demonstrated ability to bind to the nuclear receptor, perisome proliferator-activated receptor γ (PPARγ), inhibit prostaglandin E2 (PGE2) production and inhibit inducible nitric oxide production during the inflammation process.

Ingredients

Metagenics Inflavonoid Intensive Care is free from animal products, dairy protein, lactose, eggs, gluten, wheat, yeast, soy protein and salt. Free from artificial colours, flavours and preservatives.

Warnings

See Pregnancy and Breastfeeding tab

Not all cautions and contraindications are listed. For full details, references or more information contact HealthMasters in Australia on 02 4369 7770 or email reception@healthmasters.com.au.

Always read the label. Use only as directed. If symptoms persist consult your healthcare professional

Pregnancy and Breastfeeding

Pregnancy: Contraindicated.

Boswelia: Evidence states that there is no increased risk of harm to the foetus from limited use in women.[255] However, the traditional text states that Boswellia is contraindicated during pregnancy.[256] A review by the Natural Standard Research Collaboration states ‘reports in Indian literature says that the resin from Boswellia may be an emmenagogue and induce abortion’.[257]

Willow bark: it is generally not advised to use salicylate-containing medicines in pregnancy, as there is positive evidence of a harmful effect on the foetus with salicylates, although no direct restrictions are known for willow bark. [258],[259],[260],[261],[262] Use practitioner discretion.

Capsicum: it is recommended to avoid due to possible uterine stimulant effects.[263] Also, observational research suggests that intake of raw capsicum peppers during pregnancy is associated with an increased risk of sensitisation to inhalant allergens in children by the age of 2 years.[264] Use practitioner discretion.

Breastfeeding: Professional supervision is recommended.

Willow bark: not advised during lactation as salicylates are excreted in breast milk and may lead to hypersensitivity reactions. Use only under professional supervision.[265],[266],[267]

Capsicum frutescens: can sometimes lead to dermatitis in breast-fed infants when mothers ingest foods heavily spiced with capsicum peppers.[268]

References

[79] Braun L, Cohen M. Ginger. In: Herbs and Natural Supplements: an evidence-based guide. 4th ed, Vol 2. Sydney: Elsevier/Churchill Livingstone. 2015: 410-411.

[80] Mills S, Bone K. Ginger In: The Essential Guide to Herbal Safety. Philadelphia, USA:  Elsevier/Churchhill Livingstone. 2005:420-423.

[81] Skidmore-Roth L. Ginger. In: Mosby’s Handbook of Herbs & Natural Supplements 4th ed. Missouri: Mosby Elsevier. 2010:62-68.

[82] Gregory PJ, editor. Capsicum. Natural Medicines. [Online]. 2016. https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=945.  [Cited 12/01/2017].

[83] Skidmore-Roth L. Capsicum. In: Mosby’s Handbook of Herbs & Natural Supplements 4th ed. Missouri: Mosby Elsevier. 2010:134-7.

[256] Bensky, D., S Clavery, and E Stoger. 2004. Chinese herbal medicine: Materia Medica. 3rd ed. Seattle: Eastland Press.

[257] Basch E, Boon H, Davies-Heerema T, et al. Boswellia: an evidence-based systematic review by the Natural Standard Research Collaboration. J Herb Pharmacother. 2004;4(3):63-83.

[258] Braun L, Cohen M. Herbs and Natural Supplements: an evidence-based guide. 4th ed. Sydney: Elsevier/Churchill Livingstone. 2015. pp.1182-1185

[259] Ulbricht CE. Natural Standard Herb & Supplement Guide. An Evidence-based Reference. Mosby Elsevier.2010.

[260] Mills S, Bone K. Willow Bark. In: The Essential Guide to Herbal Safety. Philadelphia, USA:  Elsevier/Churchhill Livingstone. 2005.

[261] Gardner Z, McGuffin M, editors. American herbal products association’s botanical safety handbook. 2nd ed. Florida: Boca Raton. 2013.

[262] ESCOP Monographs. The Scientific Foundation for Herbal Medicinal Products. 2nd ed. New York. 2003

[263] Fetrow CW, Avila JR. Capsicum. In: Professionals Handbook of Complementary and Alternative Medicines. 3rd ed. Lippincott, Williams, Wilkins. 2004:154-8.

[264] Gregory PJ, editor. Capsicum. Natural Medicines. [Online]. 2016. https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=945. [Cited 12/01/2017].

[265] Mills S, Bone K. Willow Bark. In: The Essential Guide to Herbal Safety. Philadelphia, USA:  Elsevier/Churchhill Livingstone. 2005.

[266]Gardner Z, McGuffin M, editors. American herbal products association’s botanical safety handbook. 2nd ed. Florida: Boca Raton. 2013.

[267]ESCOP Monographs. The Scientific Foundation for Herbal Medicinal Products. 2nd ed. New York. 2003

[268]Gregory PJ, editor. Capsicum. Natural Medicines. [Online]. 2016. https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=945. [Cited 12/01/2017].

Storage

Store below 30° C