Metagenics HPA Essentials 60 tablets
Directions: Metagenics HPA Essentials
Take 1 tablet twice daily with food.
Clinical Benefits: Metagenics HPA Essentials
- Improves the adrenal gland rhythm.4 A researched trial of 52 people demonstrated a daily combination of vitamins B1 and B6, and 900 mg ascorbic acid, improved glucocorticoid function of the adrenal glands, and simultaneously normalised the rhythmic activity of the gland.5
- Vitamins B1 and B12 help protect from HPA dysfunction and regulate the cortisol clock. Vitamin B1 has been shown to reduce cortisol activity in times of stress, thereby protecting the body against excessive cortisol.8 Although mecobalamin, the active form of vitamin B12, doesn’t increase levels of cortisol in the blood, evidence suggests it helps shift the cortisol secretion peak, helping place the cortisol clock back on schedule.8
- B vitamins needed for neurotransmitter synthesis. Vitamin B6 is important due to its function as a coenzyme in the biosynthesis of neurotransmitters GABA, noradrenaline, dopamine and serotonin.6 Pyridoxal 5-phosphate, (P5P), is the biologically active form of B6.7 Vitamin B5 is involved in the synthesis of melatonin from serotonin due to its progression to Coenzyme A (CoA), which donates its acetyl group to serotonin to convert to melatonin, which has been shown to have a favourable effect on certain dysphoric mental states such as restlessness, anxiety and depression.6,8 Vitamin B5 deficiency is specifically related to decreased adrenal function and biotin deficiency has been shown to contribute to adrenal insufficiency.9
Ingredients: Metagenics HPA Essentials
|Each tablet contains:|
|Calcium ascorbate dihydrate||545mg|
|Equivalent Ascorbic acid (Vitamin C)||450mg|
|Calcium pantothenate (Vitamin B5)||300mg|
|Citrus bioflavonoids extract||50mg|
|Thiamine hydrocholoride (Vitamin B1)||50mg|
|Nicotinamide (Vitamin B3)||50mg|
|Pyridoxal 5-phosphate monohydrate (Vitamin B6)||50mg|
|Riboflavin sodium phosphate (Vitamin B2)||20mg|
|Equivalent Levomefolic acid (5-Methyltetrahydrofolate)||200µg|
|Mecobalamin (Co-methylcobalamin) (Vitamin B12)||200µg|
Metagenics HPA Essentials is free from animal products, corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, soy protein and starches. Metagenics HPA Essentials is free from artificial colours, flavours and preservatives.
Warnings: Metagenics HPA Essentials
WARNING: This product contains B6. See your healthcare professional if you experience tingling, burning or numbness.
Always read the label. Use only as directed. If symptoms persist consult your healthcare professional.
Storage: Metagenics HPA Essentials
Store below 30° C