Metagenics Bio Q-Absorb Ubiquinol

Product Video

Directions

Adults: Take 1 capsule daily with food.

Benefits

Innovative and exclusive VESIsorb® colloidal delivery system, for enhanced absorption and efficiency of orally administered CoQ10: Pharmacokinetic studies in humans have measured the relative bioavailability of Coenzyme Q10 with the VESIsorb® delivery system compared to standard oil-based CoQ10 products. VESIsorb® improved CoQ10 absorption by 622% compared to an oil-based formulation (Figure 1).2 Bioavailability of CoQ10 is low due to its poor solubility in water. VESIsorb® improves absorption by imitating the naturally occurring mixed micellar transport system in the human body. The CoQ10 is microscopically and evenly dispersed throughout the VESIsorb® delivery system allowing the transport of CoQ10 through the GI lumen to the absorptive epithelium (Figure 2).

Energy production: CoQ10 supports healthy mitochondrial function by assisting with energy production and protecting mitochondrial membranes from free radical damage.3

Cardiovascular health: Mitochondria are abundant in cardiomyocytes providing adequate ATP production for healthy cardiovascular function. CoQ10 exerts potent free radical scavenging activity in lipid and mitochondrial membranes, several clinical trials have shown CoQ10 to reduce the oxidation of LDL cholesterol. CoQ10 may also help to support healthy blood pressure in healthy people, by improving endothelium-dependant vasodilation and ß-adrenoceptor-mediated arterial relaxation. Individual’s on statin medications may benefit from CoQ10 supplementation as they deplete the body of CoQ10 by interfering with the production of mevalonic acid, a precursor in the synthesis of CoQ10.

Certain groups benefit from supplementing with the active (reduced) form of CoQ10, ubiquinol, over ubiquinone due to impaired endogenous conversion.8 Ubiquinone is converted to ubiquinol by NADH dehydrogenase, which passes electrons from NADH to ubidecarenone to form ubiquinol.9 This process can be hindered by high levels of oxidative stress and some medications. 10,11,12

Ingredients

Metagenics Bio Q-Absorb Ubiquinol is Free from corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast and starches. Free from artificial colours and flavours.

Excipients

Colour, D-alpha-tocopheryl acetate, Gelatin, Glycerol, Linoleic acid, Medium chain triglycerides, Olive Oil, Orange Oil, PEG-35 castor oil, PEG-40 hydrogenated castor oil, Polysorbate 80, Purified water.

For more information about excipients used in this product, see a full excipient list HERE

Warnings

Contraindications

None of note.

Moderate Level Cautions

Warfarin and other anticoagulant medications - Concomitant use might reduce the anticoagulation effects of warfarin and other anticoagulant drugs, (such as phenindione).[109],[110] Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like pro-coagulant effects. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients that have a stable INR.

Closely monitor patients taking warfarin and coenzyme Q10. Dose adjustment may be necessary.[111],[112]

Low Level Cautions

None of note.

Pregnancy and Breastfeeding

Pregnancy

A review did not identify any concerns for use during pregnancy, however safety has not been conclusively established in humans.

Note: No risks found in humans although research is limited or unavailable prior to 20 weeks gestation.[113],[114]

Breastfeeding

A review did not identify any concerns for use during breastfeeding, however safety has not been conclusively established in humans.

Note: No risks found in humans although research is limited or unavailable.[115],[116]

Storage

Store below 30° C

FAQ's

Q1 What is the difference between Metagenics Bio-Q Absorb 150 and Metagenics Bio-Q Absorb Ubiquinol?

A Metagenics Bio-Q Absorb 150 contains CoQ10 in the form of Ubidecarenone which is converted in the body to Ubiquinol which is the active form. This is more suitable for younger people.

Metagenics Bio-Q Absorb Ubiquinol contains CoQ10 in the form of Ubiquinol-10 which is the active form and does not need to be converted in the body. This is better as we age because with age we are less efficient at converting Ubidecarenone to Ubiquinol.

Q2 What are the benefits of water-soluble?

A Both the above forms are water soluble and are six times more absorbable than other forms of CoQ10 which are fat soluble. See the video in the Product Video TAB.

Q3 If Metagenics Bio-Q Absorb Ubiquinol is unavailable can I swap to Bio-Q Absorb 150?

A You can swap from Metagenics Bio-Q Absorb Ubiquinol to Metagenics Bio-Q Absorb 150 however you may need to take two capsules of Metagenics Bio-Q Absorb 150 to get the same benefits of Metagenics Bio-Q Absorb Ubiquinol depending on your age. See Q1 above.

TruQuality

Metagenics has stringent testing policies and practices means that Practitioners can prescribe products with complete confidence to deliver an exceptional patient product experience that provides health outcomes. When Metagenics say "check us", they mean it. It's easy to say we care about quality - let us show you. TruQuality grants full visibility to product ingredients and testing information for every single product we make.

For more information about product testing, click HERE.

To learn about excipients used in this product, see our full excipient list HERE.

The products listed below are suggestions that may be used as a substitute if the product you are looking for is unavailable.

• Metagenics Bio Q-Absorb 150 60 caps see FAQ's TAB below
• Bioclinic Naturals Ubiquinol 300mg
• BioMedica SynQ10
• See our range of CoQ10

Can't see an appropriate product, or have any other questions? You can contact HealthMasters for assistance HERE