Designs For Health Liposomal Vitamin C 175ml
Details: Designs For Health Liposomal Vitamin C
Liposome structure and function
A liposome is a vesicle made up of at least one phospholipid bilayer, which can be used to deliver hydro- or lipophilic drugs into the cell.
The liposome vesicle’s phospholipid bilayer merges with the phospholipid bilayer of the cell wall, releasing the nutrient into the cell interior (see image)
Liposomes can range in size, with smaller vesicles giving greater absorption and cellular uptake, being cleared at a slower rate giving greater opportunity for absorption, and being able to be absorbed from the buccal cells meaning they get to the cell more quickly than waiting for absorption into the bloodstream from the stomach.
The liposomes in Designs for Health products are 50-100nm in size.
Design for health's Liposomal vitamin C provides this key foundational nutrient formulated with Liposomal Technology for optional absorption and bio-availability.
Each 5ml serve provides 1000mg of sodium ascorbate, with the sodium facilitating the absorption of vitamin C via the sodium-dependent transporters Vitamin C is the key nutrient of Immune system, adrenal function, collagen formation, skin and cardiovascular health.
Vitamin C also offers antioxidant support via its ability to recycle vitamin E and glutathione.
Benefits of liposomal delivery
- Facilitates absorption in the buccal cells
- Facilitates gastrointestinal uptake
- Prevents breakdown by stomach acid
- Able to incorporate both hydro- and lipophilic agents
- Reduces risk of side effects
- Increased circulation time with smaller nanoparticles (inverse relationship between particle size and clearance time)
- Increased absorption with smaller particle size (9-fold increase from 236nm to 97nm and 34-fold higher at 64nm)
- Increased patient compliance for those who cannot or prefer not to swallow tablets
- Increased ability for flexible dosing
Immune system support
Ascorbic acid (vitamin C) is commonly linked to the immune system. In vitro, vitamin C has been shown to positively affect the production and function of neutrophils, lymphocytes and phagocytes.
Vitamin C is also protective for these leukocytes, neutralising the reactive oxygen species (ROS) released by leukocytes to kill pathogens before they can damage healthy endogenous cells.
Other In vitro studies have shown vitamin C to increase interferon production – a type of cytokine with an antiviral effect. For daily immune system support, vitamin C intake should be at a level which maintains or saturates plasma levels – 100- 200mg per day minimum – while intake during infection should be considerably higher to meet the increased demand.
Vitamin C acts as an important cofactor for the hydroxylation of proline and lysine – a necessary step in collagen formation.
In vitro, treatment with vitamin C increased collagen secretion in skin fibroblasts and resulted in more pepsin-resistant collagen.
It is more difficult to measure the effect of vitamin C on collagen formation in vivo, though mouse models have demonstrated increased stabilisation of collagen and stimulated mRNA collagen production.
In mouse models, the addition of vitamin C to drinking water or delivered via intraperitoneal infusion resulted in higher collagen deposition in wounds, lower levels of pro-inflammatory mediators and increased expression in genes which induce wound healing, resulting in greater healing at 7- and 14-day measures.
Leukocytes are important for wound healing. One type of leukocyte, neutrophils, are active during the initial inflammatory stage, migrating to the wounded area to release ROS and antimicrobial proteins.
These then undergo apoptosis and are cleared, ending the inflammatory phase of healing.
Vitamin C influences each of these initial steps.
Vitamin C is one of the body’s principle non-enzymatic antioxidants, protecting the cells from the ROS created during immune system function, every-day metabolism and toxin exposure.
Directions for use: Designs For Health Liposomal Vitamin C
Take 5ml (1 teaspoon) daily, or as directed by your healthcare professional. Hold in mouth for 30 seconds before swallowing. Take on an empty stomach.
Ingredients: Designs For Health Liposomal Vitamin C
|Active ingredients per 5ml serve:|
|Equivalent to vitamin C||1g|
Excipients: Designs For Health Liposomal Vitamin C
Excipients: Sunflower lecithin, purified water, glycerol, ethanol, lemon oil
Designs For Health Liposomal Vitamin C does not contain gluten, dairy, lactose, seeds or nuts.
Cautions/Contra-Indications: Designs For Health Liposomal Vitamin C
If symptoms persist consult your healthcare practitioner
Contains 12% ethanol & 130mg of sodium per serve.
Should not be used in children under 2 years without medical advice
If symptoms persist consult your healthcare practitioner.
Storage: Designs For Health Liposomal Vitamin C
Store below 25°C away from direct sunlight.
*Refrigeration recommended after opening.*