{"id":6875979415710,"title":"Designs For Health FloraMyces 60 caps","handle":"designs-for-health-floramyces-60-caps","description":"\u003ch2\u003eDesigns For Health FloraMyces 60 caps\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eSupports healthy digestive system and reduced symptom occurrence of traveller’s diarrhoea\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eSize: 60 capsules Serving per pack: 30 - 60\u003c\/p\u003e\n\u003cp\u003eOverview of Designs For Health FloraMyces:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eProvides 500 mg Saccharomyces cerevisiae (Boulardii) per hard capsule\u003c\/li\u003e\n\u003cli\u003eRelieves diarrhoea\u003c\/li\u003e\n\u003cli\u003eHelps reduce occurrence of symptoms of traveller’s diarrhoea when travelling\u003c\/li\u003e\n\u003cli\u003eMaintains healthy digestive system function\u003c\/li\u003e\n\u003cli\u003eSupports beneficial bacteria during antibiotic use in adults and children\u003c\/li\u003e\n\u003cli\u003eShelf-stable, low-excipient, dairy-free formula\u003c\/li\u003e\n\u003cli\u003eVegan friendly\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDesigns For Health FloraMyces No added: Gluten, soy, dairy or nuts.\u003c\/p\u003e\n\u003cp\u003eDesigns For Health FloraMyces AUST L 308218\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDetails\u003c\/h5\u003e\n\u003ch2\u003eDescription: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eA probiotic yeast\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eSaccharomyces cerevisiae (Boulardii) (also known as Saccharomyces boulardii or SB) is an unusual probiotic. Most probiotics are beneficial bacteria, but S. boulardii is a yeast. Unrelated to the yeasts which can cause disease, like candida,\u003c\/p\u003e\n\u003cp\u003eS. boulardii was identified in the 1920s as an antidiarrhoeal agent after the microbiologist Henri Boulard found that indigenous peoples who consumed a drink prepared from mangosteen and lychee skins did not develop diarrhoea.\u003c\/p\u003e\n\u003cp\u003eAn important function of the intestinal epithelium is to act as a barrier to prevent bacteria and other microorganisms from crossing into the body tissues. The tight junctions between epithelial cells can widen due to lifestyle, disease or pathogens, compromising the barrier. One way in which S. boulardii protects against infection is by maintaining the structure of tight junctions.\u003c\/p\u003e\n\u003cp\u003eWhen certain pathogenic bacteria enter into the intestinal lumen, the presence of S. boulardii can mitigate the harmful effect. Not only by maintenance of the tight junctions but also by acting directly on the pathogen.\u003c\/p\u003e\n\u003cp\u003eAn oft-studied pathogen, and the effect of S. boulardii on it, is Clostridium difficile. C. difficile emits two toxins, toxin A and toxin B, which are pro-inflammatory. Animal models propose two mechanisms of action of S. boulardii during C. difficile infection: inhibition of adhesion of toxin A to its receptor, and an immunomodulatory effect whereby S. boulardii increases the circulation of anti-toxin A.\u003c\/p\u003e\n\u003cp\u003eSupplementation with S. boulardii has been found to increase levels of Bacteroides and decrease the relative level of Firmicutes. Low levels of Bacteroides have been associated with inflammation of the gut. A high level of Firmicutes is thought to be associated with weight gain.4 It is likely that dysbiosis is a causal factor to these complaints, rather than a side-effect.\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eGnosis Biootic S. boulardii\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eThe S. boulardii in FloraMyces is Gnosis Biootic. Their in-house production from initial fermentation to end product gives a guarantee of quality, with superior stability and a long shelf-life.\u003c\/p\u003e\n\u003cp\u003eGnosis Biootic is lactose-free, gluten-free, kosher, halal and verified by the Non-GMO Project.\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eSupportive during antibiotic treatment \u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eAntibiotic-associated diarrhoea (AAD) is a common side effect of antibiotic therapy. While both bacterial probiotics and S. boulardii can be beneficial for helping to reduce the symptoms and occurrence of AAD, bacterial probiotics are subject to the effect of the antibiotic potentially rendering them less effective. Unlike bacterial probiotics, S. boulardii is not affected by antibiotics.\u003c\/p\u003e\n\u003cp\u003eSeveral systematic reviews and meta-analyses found that S. boulardii reduced the risk of AAD from 17.7-18.7% to 8.0- 8.5% compared with placebo in adults, and from 20.9% to 8.8% in children, or a reduction in relative risk of AAD of 50% or more in children taking S. boulardii.\u003c\/p\u003e\n\u003cp\u003eSeveral studies have shown that taking S. boulardii during and after antibiotic therapy helps to protect the microbiome from negative effects of the antibiotic and helps the microbiome to return to its normal state at an accelerated rate.\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eSupportive while travelling\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eTraveller’s diarrhoea is a common complaint, affecting 20-40 million people a year. Despite increasing awareness of behavioural modifications to prevent traveller’s diarrhoea (for example drinking only bottled water and not taking ice in drinks) there has been a little drop in incidence. Traveller’s diarrhoea is thought to occur from increased exposure to pathogenic bacteria with concurrent dysbiosis due to stress while travelling, medications and dietary changes.\u003c\/p\u003e\n\u003cp\u003eA systematic review and meta-analysis of probiotics as a prophylactic against traveller’s diarrhoea found that S. boulardii had the strongest evidence of effectiveness for preventing traveller’s diarrhoea. This is likely due to its ability to maintain a healthy gut microbiome and its immunomodulatory effect in the presence of pathogens.\u003c\/p\u003e\n\u003cp\u003eUnlike many bacterial probiotics, S. boulardii does not need to be refrigerated. This makes it a convenient preventative to traveller’s diarrhoea, negating the need for worry over storage.\u003c\/p\u003e\n\u003ch5\u003eDirections\u003c\/h5\u003e\n\u003ch2\u003eDirections: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eAdults: Take 1 – 2 capsules per day or as directed by your healthcare professional.\u003c\/p\u003e\n\u003cp\u003eAlways read the label. Follow the directions for use. If symptoms persist, worsen, or change unexpectedly, talk to your health professional. This medicine may not be right for you. Read the warnings before purchase.\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eActive Ingredients (per vegetarian hard capsule)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSaccharomyces cerevisiae (Boulardii)\u003c\/td\u003e\n\u003ctd\u003e500mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eHypromellose\u003c\/p\u003e\n\u003ch5\u003eAllergen Information\u003c\/h5\u003e\n\u003ch2\u003eAllergen Information: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eNo added: Gluten, Lactose, Dairy, Seed or Nuts\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eStore below 25°C away from direct sunlight.\u003c\/p\u003e\n\u003cp\u003eUnlike many bacterial probiotics, S. boulardii does not need to be refrigerated. This makes it a convenient preventative to traveller’s diarrhoea, negating the need for worry over storage.\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eSeek medical advice if  diarrhoea persists for more than 6 hours in infants under 6 months, 12 hours in children under 3 years, 24 hours in children aged 3 to 6 years or 48 hours in adults\u003c\/p\u003e\n\u003ch5\u003ePrescribing Information\u003c\/h5\u003e\n\u003ch2\u003ePrescribing Information: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eContraindicated in individuals have a known yeast allergy.10\u003c\/p\u003e\n\u003cp\u003eSaccharomyces boulardii is a yeast. Theoretically, antifungals might decrease its effectiveness. Antifungals include fluconazole (Diflucan), caspofungin (Cancidas), itraconazole (Sporanox) amphotericin (Ambisome), and others.10\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2022-10-11T16:14:22+11:00","created_at":"2021-08-06T15:37:28+10:00","vendor":"Designs For Health","type":"Designs For Health Naturopathic Medicines","tags":["800px","Designs For Health","Naturopathic","PB"],"price":4856,"price_min":4856,"price_max":4856,"available":true,"price_varies":false,"compare_at_price":5395,"compare_at_price_min":5395,"compare_at_price_max":5395,"compare_at_price_varies":false,"variants":[{"id":40475363213470,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"DFHFloraMyces60C","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Designs For Health FloraMyces 60 caps","public_title":null,"options":["Default Title"],"price":4856,"weight":0,"compare_at_price":5395,"inventory_quantity":9992,"inventory_management":"shopify","inventory_policy":"deny","barcode":"9353993000054","requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealth.jpg?v=1654830355","\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealthDirections.jpg?v=1654830370","\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealthIngredients.jpg?v=1654830387"],"featured_image":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealth.jpg?v=1654830355","options":["Title"],"media":[{"alt":"Designs For Health FloraMyces 10% off RRP at HealthMasters Designs For Health","id":22612560445598,"position":1,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealth.jpg?v=1654830355"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealth.jpg?v=1654830355","width":1200},{"alt":"Designs For Health FloraMyces 10% off RRP at HealthMasters Designs For Health Directions","id":22612560478366,"position":2,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealthDirections.jpg?v=1654830370"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealthDirections.jpg?v=1654830370","width":1200},{"alt":"Designs For Health FloraMyces 10% off RRP at HealthMasters Designs For Health Ingredients","id":22612560511134,"position":3,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealthIngredients.jpg?v=1654830387"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthFloraMyces10_offRRPatHealthMastersDesignsForHealthIngredients.jpg?v=1654830387","width":1200}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch2\u003eDesigns For Health FloraMyces 60 caps\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eSupports healthy digestive system and reduced symptom occurrence of traveller’s diarrhoea\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eSize: 60 capsules Serving per pack: 30 - 60\u003c\/p\u003e\n\u003cp\u003eOverview of Designs For Health FloraMyces:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eProvides 500 mg Saccharomyces cerevisiae (Boulardii) per hard capsule\u003c\/li\u003e\n\u003cli\u003eRelieves diarrhoea\u003c\/li\u003e\n\u003cli\u003eHelps reduce occurrence of symptoms of traveller’s diarrhoea when travelling\u003c\/li\u003e\n\u003cli\u003eMaintains healthy digestive system function\u003c\/li\u003e\n\u003cli\u003eSupports beneficial bacteria during antibiotic use in adults and children\u003c\/li\u003e\n\u003cli\u003eShelf-stable, low-excipient, dairy-free formula\u003c\/li\u003e\n\u003cli\u003eVegan friendly\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDesigns For Health FloraMyces No added: Gluten, soy, dairy or nuts.\u003c\/p\u003e\n\u003cp\u003eDesigns For Health FloraMyces AUST L 308218\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDetails\u003c\/h5\u003e\n\u003ch2\u003eDescription: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eA probiotic yeast\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eSaccharomyces cerevisiae (Boulardii) (also known as Saccharomyces boulardii or SB) is an unusual probiotic. Most probiotics are beneficial bacteria, but S. boulardii is a yeast. Unrelated to the yeasts which can cause disease, like candida,\u003c\/p\u003e\n\u003cp\u003eS. boulardii was identified in the 1920s as an antidiarrhoeal agent after the microbiologist Henri Boulard found that indigenous peoples who consumed a drink prepared from mangosteen and lychee skins did not develop diarrhoea.\u003c\/p\u003e\n\u003cp\u003eAn important function of the intestinal epithelium is to act as a barrier to prevent bacteria and other microorganisms from crossing into the body tissues. The tight junctions between epithelial cells can widen due to lifestyle, disease or pathogens, compromising the barrier. One way in which S. boulardii protects against infection is by maintaining the structure of tight junctions.\u003c\/p\u003e\n\u003cp\u003eWhen certain pathogenic bacteria enter into the intestinal lumen, the presence of S. boulardii can mitigate the harmful effect. Not only by maintenance of the tight junctions but also by acting directly on the pathogen.\u003c\/p\u003e\n\u003cp\u003eAn oft-studied pathogen, and the effect of S. boulardii on it, is Clostridium difficile. C. difficile emits two toxins, toxin A and toxin B, which are pro-inflammatory. Animal models propose two mechanisms of action of S. boulardii during C. difficile infection: inhibition of adhesion of toxin A to its receptor, and an immunomodulatory effect whereby S. boulardii increases the circulation of anti-toxin A.\u003c\/p\u003e\n\u003cp\u003eSupplementation with S. boulardii has been found to increase levels of Bacteroides and decrease the relative level of Firmicutes. Low levels of Bacteroides have been associated with inflammation of the gut. A high level of Firmicutes is thought to be associated with weight gain.4 It is likely that dysbiosis is a causal factor to these complaints, rather than a side-effect.\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eGnosis Biootic S. boulardii\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eThe S. boulardii in FloraMyces is Gnosis Biootic. Their in-house production from initial fermentation to end product gives a guarantee of quality, with superior stability and a long shelf-life.\u003c\/p\u003e\n\u003cp\u003eGnosis Biootic is lactose-free, gluten-free, kosher, halal and verified by the Non-GMO Project.\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eSupportive during antibiotic treatment \u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eAntibiotic-associated diarrhoea (AAD) is a common side effect of antibiotic therapy. While both bacterial probiotics and S. boulardii can be beneficial for helping to reduce the symptoms and occurrence of AAD, bacterial probiotics are subject to the effect of the antibiotic potentially rendering them less effective. Unlike bacterial probiotics, S. boulardii is not affected by antibiotics.\u003c\/p\u003e\n\u003cp\u003eSeveral systematic reviews and meta-analyses found that S. boulardii reduced the risk of AAD from 17.7-18.7% to 8.0- 8.5% compared with placebo in adults, and from 20.9% to 8.8% in children, or a reduction in relative risk of AAD of 50% or more in children taking S. boulardii.\u003c\/p\u003e\n\u003cp\u003eSeveral studies have shown that taking S. boulardii during and after antibiotic therapy helps to protect the microbiome from negative effects of the antibiotic and helps the microbiome to return to its normal state at an accelerated rate.\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eSupportive while travelling\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eTraveller’s diarrhoea is a common complaint, affecting 20-40 million people a year. Despite increasing awareness of behavioural modifications to prevent traveller’s diarrhoea (for example drinking only bottled water and not taking ice in drinks) there has been a little drop in incidence. Traveller’s diarrhoea is thought to occur from increased exposure to pathogenic bacteria with concurrent dysbiosis due to stress while travelling, medications and dietary changes.\u003c\/p\u003e\n\u003cp\u003eA systematic review and meta-analysis of probiotics as a prophylactic against traveller’s diarrhoea found that S. boulardii had the strongest evidence of effectiveness for preventing traveller’s diarrhoea. This is likely due to its ability to maintain a healthy gut microbiome and its immunomodulatory effect in the presence of pathogens.\u003c\/p\u003e\n\u003cp\u003eUnlike many bacterial probiotics, S. boulardii does not need to be refrigerated. This makes it a convenient preventative to traveller’s diarrhoea, negating the need for worry over storage.\u003c\/p\u003e\n\u003ch5\u003eDirections\u003c\/h5\u003e\n\u003ch2\u003eDirections: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eAdults: Take 1 – 2 capsules per day or as directed by your healthcare professional.\u003c\/p\u003e\n\u003cp\u003eAlways read the label. Follow the directions for use. If symptoms persist, worsen, or change unexpectedly, talk to your health professional. This medicine may not be right for you. Read the warnings before purchase.\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eActive Ingredients (per vegetarian hard capsule)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSaccharomyces cerevisiae (Boulardii)\u003c\/td\u003e\n\u003ctd\u003e500mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eHypromellose\u003c\/p\u003e\n\u003ch5\u003eAllergen Information\u003c\/h5\u003e\n\u003ch2\u003eAllergen Information: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eNo added: Gluten, Lactose, Dairy, Seed or Nuts\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eStore below 25°C away from direct sunlight.\u003c\/p\u003e\n\u003cp\u003eUnlike many bacterial probiotics, S. boulardii does not need to be refrigerated. This makes it a convenient preventative to traveller’s diarrhoea, negating the need for worry over storage.\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eSeek medical advice if  diarrhoea persists for more than 6 hours in infants under 6 months, 12 hours in children under 3 years, 24 hours in children aged 3 to 6 years or 48 hours in adults\u003c\/p\u003e\n\u003ch5\u003ePrescribing Information\u003c\/h5\u003e\n\u003ch2\u003ePrescribing Information: Designs For Health FloraMyces\u003c\/h2\u003e\n\u003cp\u003eContraindicated in individuals have a known yeast allergy.10\u003c\/p\u003e\n\u003cp\u003eSaccharomyces boulardii is a yeast. Theoretically, antifungals might decrease its effectiveness. Antifungals include fluconazole (Diflucan), caspofungin (Cancidas), itraconazole (Sporanox) amphotericin (Ambisome), and others.10\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}

Designs For Health FloraMyces 60 caps

Maximum quantity available reached.
Product Details

Designs For Health FloraMyces 60 caps

Supports healthy digestive system and reduced symptom occurrence of traveller’s diarrhoea

Size: 60 capsules Serving per pack: 30 - 60

Overview of Designs For Health FloraMyces:

  • Provides 500 mg Saccharomyces cerevisiae (Boulardii) per hard capsule
  • Relieves diarrhoea
  • Helps reduce occurrence of symptoms of traveller’s diarrhoea when travelling
  • Maintains healthy digestive system function
  • Supports beneficial bacteria during antibiotic use in adults and children
  • Shelf-stable, low-excipient, dairy-free formula
  • Vegan friendly

Designs For Health FloraMyces No added: Gluten, soy, dairy or nuts.

Designs For Health FloraMyces AUST L 308218

Description: Designs For Health FloraMyces

A probiotic yeast

Saccharomyces cerevisiae (Boulardii) (also known as Saccharomyces boulardii or SB) is an unusual probiotic. Most probiotics are beneficial bacteria, but S. boulardii is a yeast. Unrelated to the yeasts which can cause disease, like candida,

S. boulardii was identified in the 1920s as an antidiarrhoeal agent after the microbiologist Henri Boulard found that indigenous peoples who consumed a drink prepared from mangosteen and lychee skins did not develop diarrhoea.

An important function of the intestinal epithelium is to act as a barrier to prevent bacteria and other microorganisms from crossing into the body tissues. The tight junctions between epithelial cells can widen due to lifestyle, disease or pathogens, compromising the barrier. One way in which S. boulardii protects against infection is by maintaining the structure of tight junctions.

When certain pathogenic bacteria enter into the intestinal lumen, the presence of S. boulardii can mitigate the harmful effect. Not only by maintenance of the tight junctions but also by acting directly on the pathogen.

An oft-studied pathogen, and the effect of S. boulardii on it, is Clostridium difficile. C. difficile emits two toxins, toxin A and toxin B, which are pro-inflammatory. Animal models propose two mechanisms of action of S. boulardii during C. difficile infection: inhibition of adhesion of toxin A to its receptor, and an immunomodulatory effect whereby S. boulardii increases the circulation of anti-toxin A.

Supplementation with S. boulardii has been found to increase levels of Bacteroides and decrease the relative level of Firmicutes. Low levels of Bacteroides have been associated with inflammation of the gut. A high level of Firmicutes is thought to be associated with weight gain.4 It is likely that dysbiosis is a causal factor to these complaints, rather than a side-effect.

Gnosis Biootic S. boulardii

The S. boulardii in FloraMyces is Gnosis Biootic. Their in-house production from initial fermentation to end product gives a guarantee of quality, with superior stability and a long shelf-life.

Gnosis Biootic is lactose-free, gluten-free, kosher, halal and verified by the Non-GMO Project.

Supportive during antibiotic treatment

Antibiotic-associated diarrhoea (AAD) is a common side effect of antibiotic therapy. While both bacterial probiotics and S. boulardii can be beneficial for helping to reduce the symptoms and occurrence of AAD, bacterial probiotics are subject to the effect of the antibiotic potentially rendering them less effective. Unlike bacterial probiotics, S. boulardii is not affected by antibiotics.

Several systematic reviews and meta-analyses found that S. boulardii reduced the risk of AAD from 17.7-18.7% to 8.0- 8.5% compared with placebo in adults, and from 20.9% to 8.8% in children, or a reduction in relative risk of AAD of 50% or more in children taking S. boulardii.

Several studies have shown that taking S. boulardii during and after antibiotic therapy helps to protect the microbiome from negative effects of the antibiotic and helps the microbiome to return to its normal state at an accelerated rate.

Supportive while travelling

Traveller’s diarrhoea is a common complaint, affecting 20-40 million people a year. Despite increasing awareness of behavioural modifications to prevent traveller’s diarrhoea (for example drinking only bottled water and not taking ice in drinks) there has been a little drop in incidence. Traveller’s diarrhoea is thought to occur from increased exposure to pathogenic bacteria with concurrent dysbiosis due to stress while travelling, medications and dietary changes.

A systematic review and meta-analysis of probiotics as a prophylactic against traveller’s diarrhoea found that S. boulardii had the strongest evidence of effectiveness for preventing traveller’s diarrhoea. This is likely due to its ability to maintain a healthy gut microbiome and its immunomodulatory effect in the presence of pathogens.

Unlike many bacterial probiotics, S. boulardii does not need to be refrigerated. This makes it a convenient preventative to traveller’s diarrhoea, negating the need for worry over storage.

Directions: Designs For Health FloraMyces

Adults: Take 1 – 2 capsules per day or as directed by your healthcare professional.

Always read the label. Follow the directions for use. If symptoms persist, worsen, or change unexpectedly, talk to your health professional. This medicine may not be right for you. Read the warnings before purchase.

Ingredients: Designs For Health FloraMyces

Active Ingredients (per vegetarian hard capsule)
Saccharomyces cerevisiae (Boulardii) 500mg

Excipients: Designs For Health FloraMyces

Hypromellose

Allergen Information: Designs For Health FloraMyces

No added: Gluten, Lactose, Dairy, Seed or Nuts

Storage: Designs For Health FloraMyces

Store below 25°C away from direct sunlight.

Unlike many bacterial probiotics, S. boulardii does not need to be refrigerated. This makes it a convenient preventative to traveller’s diarrhoea, negating the need for worry over storage.

Warnings: Designs For Health FloraMyces

Seek medical advice if  diarrhoea persists for more than 6 hours in infants under 6 months, 12 hours in children under 3 years, 24 hours in children aged 3 to 6 years or 48 hours in adults

Prescribing Information: Designs For Health FloraMyces

Contraindicated in individuals have a known yeast allergy.10

Saccharomyces boulardii is a yeast. Theoretically, antifungals might decrease its effectiveness. Antifungals include fluconazole (Diflucan), caspofungin (Cancidas), itraconazole (Sporanox) amphotericin (Ambisome), and others.10

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