{"id":8338295947494,"title":"BioActiv HealthCare NMN","handle":"bioactiv-healthcare-nmn","description":"\u003ch2\u003eBioActiv HealthCare NMN\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eNicotinamide Mono Nucleotide\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eBioActive HealthCare Compounding Range\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbig\u003eBioActiv HealthCare NMN \u003cspan style=\"color: #ff2a00;\" data-mce-style=\"color: #ff2a00;\"\u003e10% off RRP\u003c\/span\u003e\u003c\/big\u003e\u003c\/p\u003e\n\u003cp\u003eSize: 50g\u003c\/p\u003e\n\u003cp\u003eBioActiv HealthCare NMN Summary:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNMN (Methyl Sulfonyl Methane) is a powerful anti-aging molecule for NADH production which declines from age 50+.\u003c\/li\u003e\n\u003cli\u003eNADH repairs our DNA and maintains maximum mitochondrial energy production.\u003c\/li\u003e\n\u003cli\u003eBoosts peak performance and recovery.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBioActiv HealthCare NMN has No artificial colours, flavours, sweeteners or preservatives. No fillers.\u003c\/p\u003e\n\u003cp\u003eBioActiv HealthCare NMN is part of the BioActiv HealthCare Compounding Range\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe products listed below are suggestions that may be used as a substitute if the product you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/shop.healthmasters.com.au\/collections\/bioactiv-healthcare-10-off-rrp\/products\/bioactiv-healthcare-nmn\" title=\"BioActiv HealthCare NMN 10% off RRP | HealthMasters BioActiv HealthCare\" target=\"_blank\"\u003eBioActiv HealthCare NMN\u003c\/a\u003e - NMN (Nicotinamide Mono Nucleotide) 6-800mg per scoop\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/rn-labs-nicotinamide-riboside-nr\" title=\"Designs For Health NR Supreme 10% off RRP | HealthMasters Designs For Health\" target=\"_blank\"\u003eDesigns For Health NR Supreme\u003c\/a\u003e\u003c\/span\u003e - NR (Nicotinamide Riboside Chloride) 300mg per capsule\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/rn-labs-nicotinamide-riboside-nr\" title=\"RN Labs Nicotinamide Riboside NR 10% off RRP | HealthMasters RN Labs\" target=\"_blank\"\u003eRN Labs Nicotinamide Riboside NR\u003c\/a\u003e\u003c\/span\u003e - NR (Nicotinamide Riboside Chloride) 300mg per capsule\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNote:\u003c\/p\u003e\n\u003cp\u003eIn the body, NR (Nicotinamide Riboside) converts to NMN (Nicotinamide Mono Nucleotide) which is then converted in the cell to Nicotinamide NAD (Adenine Dinucleotide).\u003c\/p\u003e\n\u003cp\u003eCan't see an appropriate product, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" title=\"Contact HealthMasters For Assistance\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eDirections for use as per label\u003c\/p\u003e\n\u003cp\u003e1 scoop contains 600mg-800mg\u003c\/p\u003e\n\u003cp\u003eFrom the data available on taking NMN supplements. Studies have found health benefits with doses from 250mg of NMN per day, up to a maximum of 1,200mg per day. The medium dose is 600mg to 800mg.\u003c\/p\u003e\n\u003cp\u003eThree studies looked at the effects of taking NMN supplements over multiple doses and safety does not appear to differ across different doses used in the ranges above.\u003c\/p\u003e\n\u003cp\u003eAmateur runners were studied for the aerobic benefits of NMN supplementation. Doses of NMN at 600mg were compared with doses of MNM at 300mg and there was no difference observed in the benefits observed at a high dose of MNM 1200mg compared with a medium dose of 600 mg.\u003c\/p\u003e\n\u003cp\u003eEarly studies suggest taking NMN at doses of up to 1,200mg per day may provide health benefits related to insulin sensitivity, aerobic function and fatigue, with minimal risk of undesirable side effects.\u003c\/p\u003e\n\u003cp\u003eWhile animal studies have found that MNM supplements reversed many age-related health effects, the evidence in humans is still limited.\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eNMN (Nicotinamide Mono Nucleotide)\u003c\/p\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eNo artificial colours, flavours, sweeteners or preservatives. No fillers.\u003c\/p\u003e\n\u003ch5\u003eFree From\u003c\/h5\u003e\n\u003ch2\u003eFree From: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eNo artificial colours, flavours, sweeteners or preservatives. No fillers.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eStore in a cool dry place below 25°C.\u003c\/p\u003e\n\u003ch5\u003eCautions\u003c\/h5\u003e\n\u003ch2\u003eCautions: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eKeep out of reach of children.\u003c\/li\u003e\n\u003cli\u003eDo not use if tamper evident seal is broken or missing.\u003c\/li\u003e\n\u003cli\u003eEnsure lid tightly closed after use\u003c\/li\u003e\n\u003cli\u003eContains a silica gel sachet. Do not swallow.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eProduct Information\u003c\/h5\u003e\n\u003ch2\u003eProduct Information: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eThe following is an excerpt from \u003cem\u003eThe Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule\u003c\/em\u003e (Shade C., 2020).\u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003eIn June of 2018, the World Health Organization (WHO) released the 11th edition of its International Classification of Diseases, and for the first time added aging.1 The classification of aging as a disease paves the way for new research into novel therapeutics to delay or reverse age-related illnesses such as cancer, cardiovascular and metabolic disease, and neurodegeneration.2,3 Nutrient sensing systems have been an intense focus of investigation, including mTOR (the mammalian target of rapamycin) for regulating protein synthesis and cell growth; AMPK (activated protein kinase) for sensing low energy states; and sirtuins, a family of seven proteins critical to DNA expression and aging, which can only function in conjunction with NAD+ (nicotinamide adenine dinucleotide), a coenzyme present in all living cells.4\u003c\/p\u003e\n\u003cp\u003eAcross the kingdom of life, an increase in intracellular levels of NAD+ triggers shifts that enhance survival, including boosting energy production and upregulating cellular repair.5 In fact, the slow, ineluctable process of aging has been described as a “cascade of robustness breakdown triggered by a decrease in systemic NAD+ biosynthesis and the resultant functional defects in susceptible organs and tissues.”6 Aging is marked by epigenetic shifts, genomic instability, altered nutrient sensing ability, telomere attrition, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and dysregulated intercellular communication.7,8\u003c\/p\u003e\n\u003cp\u003eBy middle age, our NAD+ levels have plummeted to half that of our youth.9 Numerous studies have demonstrated that boosting NAD+ levels increases insulin sensitivity, reverses mitochondrial dysfunction, and extends lifespan.10,11 NAD+ levels can be increased by activating enzymes that stimulate the synthesis of NAD+, by inhibiting an enzyme (CD38) that degrades NAD+, and by supplementing with NAD precursors, including nicotinamide riboside(NR) and nicotinamide mononucleotide (NMN).12,13 A conceptual framework called NAD World, formulated over the last decade by developmental biologist Shin-ichiro Imai, MD, PhD, of Washington University School of Medicine, posits NMN as a critical, systemic signaling molecule that maintains biological robustness of the communication network supporting NAD+.6\u003c\/p\u003e\n\u003cp\u003eTaken orally, NMN is rapidly absorbed and converted to NAD+.14 In numerous studies, supplementation with NMN has increased NAD+ biosynthesis, suppressed age-related adipose tissue inflammation, enhanced insulin secretion and insulin action, improved mitochondrial function, improved neuronal function in the brain, and more. Here, we look at the science behind NMN, its stability, possible pharmacokinetics, transport, function, and ability to induce biosynthesis of NAD+.15 Supplementing NMN may be an effective nutraceutical anti-aging intervention, with beneficial effects on a wide array of physiological functions.16\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003eShade C. The Science Behind NMN-A Stable, Reliable NAD+Activator and Anti-Aging Molecule. Integr Med (Encinitas). 2020 Feb;19(1):12-14. PMID: 32549859; PMCID: PMC7238909. Full article and references available on \u003ca title=\"The Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7238909\/#:~:text=administered%20NMN%20is%20quickly%20synthesized,linked%20changes%20in%20gene%20expression.\" target=\"_blank\"\u003eNational Library of Medicine\u003c\/a\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eFAQ's\u003c\/h5\u003e\n\u003ch2\u003eFAQ's: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003ch3\u003eWhat is nicotinamide mononucleotide (NMN)?\u003c\/h3\u003e\n\u003cp\u003eNMN is a naturally occurring molecule that helps produce energy in the body.\u003c\/p\u003e\n\u003cp\u003eNMN is a molecule called a nucleotide. Nucleotides have many roles in the body including the production of DNA.\u003c\/p\u003e\n\u003cp\u003eNMN is converted into another molecule within the cells known as nicotinamide adenine dinucleotide (NAD). Your body needs NAD for a variety of functions involved in metabolism and energy production.\u003c\/p\u003e\n\u003cp\u003eThe amount of NAD your body can make depends on the amount of NMN available in your body.\u003c\/p\u003e\n\u003ch3\u003eWhat is the difference between NR, NMN and NAD?\u003c\/h3\u003e\n\u003cp\u003eIn the body, NR (Nicotinamide Riboside) converts to NMN (Nicotinamide Mono Nucleotide) which is then converted in the cell to NAD (Nicotinamide Adenine Dinucleotide).  \u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThe best form to take is NMN (Nicotinamide Mono Nucleotide).\u003c\/p\u003e\n\u003ch3\u003eIs it better to take a supplement containing NMN or NAD?\u003c\/h3\u003e\n\u003cp\u003eResearch has found that taking a supplement containing NMN is better than taking a NAD supplement. This is because NAD is unable to enter the cell because the cells have receptors for NMN but do not have receptors for NAD. So, it is best to take NMN because NMN can enter the cells where it is converted to NAD.\u003c\/p\u003e\n\u003cp\u003eResearchers who study NMN and NAD believe that the goal is to get NAD levels in the cells to levels closer to those levels in our youth.\u003c\/p\u003e\n\u003ch3\u003eWhy is NMN so important?\u003c\/h3\u003e\n\u003cp\u003eAll the cells in your body use NAD and NMN is required to make NAD. \u003c\/p\u003e\n\u003ch3\u003eWhat are the benefits of NAD?\u003c\/h3\u003e\n\u003cp\u003eNAD helps cells regulate a number of essential functions in cells, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eenergy metabolism\u003c\/li\u003e\n\u003cli\u003eDNA repair\u003c\/li\u003e\n\u003cli\u003egene expression\u003c\/li\u003e\n\u003cli\u003ecellular stress responses\u003c\/li\u003e\n\u003cli\u003eoxidative stress\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSufficient NMN is essential to produce enough NAD to support cell functions.\u003c\/p\u003e\n\u003ch3\u003eHow is NMN and NAD related to ageing?\u003c\/h3\u003e\n\u003cp\u003eThe levels of NMN decline naturally as we age, and, as a result, your NAD levels also decline. This contributes to some of the health effects experienced during ageing.\u003c\/p\u003e\n\u003cp\u003eLow levels of NMN and NAD can be involved in conditions including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ediabetes\u003c\/li\u003e\n\u003cli\u003eliver disease\u003c\/li\u003e\n\u003cli\u003ebrain health\u003c\/li\u003e\n\u003cli\u003eheart health\u003c\/li\u003e\n\u003cli\u003elongevity\u003c\/li\u003e\n\u003cli\u003ejet lag\u003c\/li\u003e\n\u003cli\u003emuscle function and strength\u003c\/li\u003e\n\u003cli\u003eendurance\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCan NMN increase longevity?\u003c\/h3\u003e\n\u003cp\u003eIn the cells are proteins called Sirtuins that help repair DNA. Sirtuins are linked to longevity.\u003c\/p\u003e\n\u003ch3\u003eIs NMN safe, and does it have side effects?\u003c\/h3\u003e\n\u003cp\u003eNMN is an ideal supplement to increase cellular levels of NAD. It is well-tolerated, and both human and animal studies have observed it had minimal side effects.\u003c\/p\u003e\n\u003cp\u003eResearch in humans has shown that doses of up to 1,200 mg daily are safe to consume.\u003c\/p\u003e\n\u003ch3\u003eIs NMN in food?\u003cbr\u003e\n\u003c\/h3\u003e\n\u003cp\u003eNMN is found in a variety of foods. Some NMN-rich dietary sources:\u003c\/p\u003e\n\u003cp\u003eavocados - 0.36 to 1.60mg per 100grams\u003c\/p\u003e\n\u003cp\u003ebroccoli - 0.25 to 1.12mg per 100grams\u003c\/p\u003e\n\u003cp\u003ecabbage - up to 0.9mg per 100grams\u003c\/p\u003e\n\u003cp\u003ecucumber -  small amounts\u003c\/p\u003e\n\u003cp\u003ecow’s milk -  small amounts\u003c\/p\u003e\n\u003cp\u003eedamame  -  small amounts\u003c\/p\u003e\n\u003cp\u003etomatoes - 0.26 to 0.30mg per 100grams\u003c\/p\u003e\n\u003cp\u003eraw beef - 0.06 to 0.42mg per 100grams\u003c\/p\u003e\n\u003cp\u003eStudies in mice have found that the gut absorbs NMN readily. More studies are needed to investigate how eating foods containing NMN may increase NAD levels in cells.\u003c\/p\u003e\n\u003ch3\u003eCan NMN  help with ageing?\u003c\/h3\u003e\n\u003cp\u003eNMN and NAD levels naturally decline with age. Researchers have suggested that taking NMN supplements may help with age-related health concerns.\u003c\/p\u003e\n\u003cp\u003eA study in 10 Japanese men found that taking NMN at 100, 250, or 500mg increased levels of NAD. \u003c\/p\u003e\n\u003cp\u003eInsulin resistance can develop as we age and is one of the reasons diabetes is more common in older adults. Although studies haven’t specifically looked at the effects of taking NMN supplements, the research available suggests that it may help you maintain or regain insulin sensitivity with age.\u003c\/p\u003e\n\u003cp\u003eMore studies on these effects in humans are needed to investigate this potential benefit\u003c\/p\u003e\n\u003cp\u003eTaking NMN supplements has also been shown to reduce drowsiness and improve muscle responsiveness in older adults, which may improve both physical and mental health with age.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2023-11-06T13:43:33+11:00","created_at":"2023-11-04T12:16:13+11:00","vendor":"BioActiv HealthCare","type":"BioActiv HealthCare 10% off RRP","tags":["BioActiv HealthCare","Compounding","Naturopathic","PB"],"price":7277,"price_min":7277,"price_max":7277,"available":true,"price_varies":false,"compare_at_price":8085,"compare_at_price_min":8085,"compare_at_price_max":8085,"compare_at_price_varies":false,"variants":[{"id":44021845983462,"title":"50g","option1":"50g","option2":null,"option3":null,"sku":"BiAHCNMN50G","requires_shipping":true,"taxable":true,"featured_image":{"id":40000928612582,"product_id":8338295947494,"position":1,"created_at":"2023-11-04T12:21:51+11:00","updated_at":"2023-11-06T13:45:38+11:00","alt":"BioActiv HealthCare NMN 50g Powder 10% off RRP at HealthMasters BioActiv HealthCare Compounding","width":853,"height":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioActivHealthCareNMN10_offRRPatHealthMastersBioActivHealthCareCompounding.png?v=1699238738","variant_ids":[44021845983462]},"available":true,"name":"BioActiv HealthCare NMN - 50g","public_title":"50g","options":["50g"],"price":7277,"weight":60,"compare_at_price":8085,"inventory_quantity":9992,"inventory_management":"shopify","inventory_policy":"deny","barcode":"","featured_media":{"alt":"BioActiv HealthCare NMN 50g Powder 10% off RRP at HealthMasters BioActiv HealthCare Compounding","id":32610462957798,"position":1,"preview_image":{"aspect_ratio":0.711,"height":1200,"width":853,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioActivHealthCareNMN10_offRRPatHealthMastersBioActivHealthCareCompounding.png?v=1699238738"}},"requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioActivHealthCareNMN10_offRRPatHealthMastersBioActivHealthCareCompounding.png?v=1699238738","\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioActivHealthCare10_offRRPatHealthMastersBioActivHealthCare_958fc3b2-0785-45af-8678-cde18c4ce163.png?v=1699238738"],"featured_image":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioActivHealthCareNMN10_offRRPatHealthMastersBioActivHealthCareCompounding.png?v=1699238738","options":["Select Option"],"media":[{"alt":"BioActiv HealthCare NMN 50g Powder 10% off RRP at HealthMasters BioActiv HealthCare Compounding","id":32610462957798,"position":1,"preview_image":{"aspect_ratio":0.711,"height":1200,"width":853,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioActivHealthCareNMN10_offRRPatHealthMastersBioActivHealthCareCompounding.png?v=1699238738"},"aspect_ratio":0.711,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioActivHealthCareNMN10_offRRPatHealthMastersBioActivHealthCareCompounding.png?v=1699238738","width":853},{"alt":"BioActiv HealthCare NMN 10% off RRP at HealthMasters BioActiv HealthCare Compounding Logo","id":32610453291238,"position":2,"preview_image":{"aspect_ratio":3.112,"height":338,"width":1052,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioActivHealthCare10_offRRPatHealthMastersBioActivHealthCare_958fc3b2-0785-45af-8678-cde18c4ce163.png?v=1699238738"},"aspect_ratio":3.112,"height":338,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/files\/BioActivHealthCare10_offRRPatHealthMastersBioActivHealthCare_958fc3b2-0785-45af-8678-cde18c4ce163.png?v=1699238738","width":1052}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch2\u003eBioActiv HealthCare NMN\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eNicotinamide Mono Nucleotide\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eBioActive HealthCare Compounding Range\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbig\u003eBioActiv HealthCare NMN \u003cspan style=\"color: #ff2a00;\" data-mce-style=\"color: #ff2a00;\"\u003e10% off RRP\u003c\/span\u003e\u003c\/big\u003e\u003c\/p\u003e\n\u003cp\u003eSize: 50g\u003c\/p\u003e\n\u003cp\u003eBioActiv HealthCare NMN Summary:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNMN (Methyl Sulfonyl Methane) is a powerful anti-aging molecule for NADH production which declines from age 50+.\u003c\/li\u003e\n\u003cli\u003eNADH repairs our DNA and maintains maximum mitochondrial energy production.\u003c\/li\u003e\n\u003cli\u003eBoosts peak performance and recovery.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBioActiv HealthCare NMN has No artificial colours, flavours, sweeteners or preservatives. No fillers.\u003c\/p\u003e\n\u003cp\u003eBioActiv HealthCare NMN is part of the BioActiv HealthCare Compounding Range\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe products listed below are suggestions that may be used as a substitute if the product you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/shop.healthmasters.com.au\/collections\/bioactiv-healthcare-10-off-rrp\/products\/bioactiv-healthcare-nmn\" title=\"BioActiv HealthCare NMN 10% off RRP | HealthMasters BioActiv HealthCare\" target=\"_blank\"\u003eBioActiv HealthCare NMN\u003c\/a\u003e - NMN (Nicotinamide Mono Nucleotide) 6-800mg per scoop\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/rn-labs-nicotinamide-riboside-nr\" title=\"Designs For Health NR Supreme 10% off RRP | HealthMasters Designs For Health\" target=\"_blank\"\u003eDesigns For Health NR Supreme\u003c\/a\u003e\u003c\/span\u003e - NR (Nicotinamide Riboside Chloride) 300mg per capsule\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/rn-labs-nicotinamide-riboside-nr\" title=\"RN Labs Nicotinamide Riboside NR 10% off RRP | HealthMasters RN Labs\" target=\"_blank\"\u003eRN Labs Nicotinamide Riboside NR\u003c\/a\u003e\u003c\/span\u003e - NR (Nicotinamide Riboside Chloride) 300mg per capsule\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNote:\u003c\/p\u003e\n\u003cp\u003eIn the body, NR (Nicotinamide Riboside) converts to NMN (Nicotinamide Mono Nucleotide) which is then converted in the cell to Nicotinamide NAD (Adenine Dinucleotide).\u003c\/p\u003e\n\u003cp\u003eCan't see an appropriate product, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" title=\"Contact HealthMasters For Assistance\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eDirections for use as per label\u003c\/p\u003e\n\u003cp\u003e1 scoop contains 600mg-800mg\u003c\/p\u003e\n\u003cp\u003eFrom the data available on taking NMN supplements. Studies have found health benefits with doses from 250mg of NMN per day, up to a maximum of 1,200mg per day. The medium dose is 600mg to 800mg.\u003c\/p\u003e\n\u003cp\u003eThree studies looked at the effects of taking NMN supplements over multiple doses and safety does not appear to differ across different doses used in the ranges above.\u003c\/p\u003e\n\u003cp\u003eAmateur runners were studied for the aerobic benefits of NMN supplementation. Doses of NMN at 600mg were compared with doses of MNM at 300mg and there was no difference observed in the benefits observed at a high dose of MNM 1200mg compared with a medium dose of 600 mg.\u003c\/p\u003e\n\u003cp\u003eEarly studies suggest taking NMN at doses of up to 1,200mg per day may provide health benefits related to insulin sensitivity, aerobic function and fatigue, with minimal risk of undesirable side effects.\u003c\/p\u003e\n\u003cp\u003eWhile animal studies have found that MNM supplements reversed many age-related health effects, the evidence in humans is still limited.\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eNMN (Nicotinamide Mono Nucleotide)\u003c\/p\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eNo artificial colours, flavours, sweeteners or preservatives. No fillers.\u003c\/p\u003e\n\u003ch5\u003eFree From\u003c\/h5\u003e\n\u003ch2\u003eFree From: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eNo artificial colours, flavours, sweeteners or preservatives. No fillers.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eStore in a cool dry place below 25°C.\u003c\/p\u003e\n\u003ch5\u003eCautions\u003c\/h5\u003e\n\u003ch2\u003eCautions: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eKeep out of reach of children.\u003c\/li\u003e\n\u003cli\u003eDo not use if tamper evident seal is broken or missing.\u003c\/li\u003e\n\u003cli\u003eEnsure lid tightly closed after use\u003c\/li\u003e\n\u003cli\u003eContains a silica gel sachet. Do not swallow.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eProduct Information\u003c\/h5\u003e\n\u003ch2\u003eProduct Information: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003cp\u003eThe following is an excerpt from \u003cem\u003eThe Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule\u003c\/em\u003e (Shade C., 2020).\u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003eIn June of 2018, the World Health Organization (WHO) released the 11th edition of its International Classification of Diseases, and for the first time added aging.1 The classification of aging as a disease paves the way for new research into novel therapeutics to delay or reverse age-related illnesses such as cancer, cardiovascular and metabolic disease, and neurodegeneration.2,3 Nutrient sensing systems have been an intense focus of investigation, including mTOR (the mammalian target of rapamycin) for regulating protein synthesis and cell growth; AMPK (activated protein kinase) for sensing low energy states; and sirtuins, a family of seven proteins critical to DNA expression and aging, which can only function in conjunction with NAD+ (nicotinamide adenine dinucleotide), a coenzyme present in all living cells.4\u003c\/p\u003e\n\u003cp\u003eAcross the kingdom of life, an increase in intracellular levels of NAD+ triggers shifts that enhance survival, including boosting energy production and upregulating cellular repair.5 In fact, the slow, ineluctable process of aging has been described as a “cascade of robustness breakdown triggered by a decrease in systemic NAD+ biosynthesis and the resultant functional defects in susceptible organs and tissues.”6 Aging is marked by epigenetic shifts, genomic instability, altered nutrient sensing ability, telomere attrition, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and dysregulated intercellular communication.7,8\u003c\/p\u003e\n\u003cp\u003eBy middle age, our NAD+ levels have plummeted to half that of our youth.9 Numerous studies have demonstrated that boosting NAD+ levels increases insulin sensitivity, reverses mitochondrial dysfunction, and extends lifespan.10,11 NAD+ levels can be increased by activating enzymes that stimulate the synthesis of NAD+, by inhibiting an enzyme (CD38) that degrades NAD+, and by supplementing with NAD precursors, including nicotinamide riboside(NR) and nicotinamide mononucleotide (NMN).12,13 A conceptual framework called NAD World, formulated over the last decade by developmental biologist Shin-ichiro Imai, MD, PhD, of Washington University School of Medicine, posits NMN as a critical, systemic signaling molecule that maintains biological robustness of the communication network supporting NAD+.6\u003c\/p\u003e\n\u003cp\u003eTaken orally, NMN is rapidly absorbed and converted to NAD+.14 In numerous studies, supplementation with NMN has increased NAD+ biosynthesis, suppressed age-related adipose tissue inflammation, enhanced insulin secretion and insulin action, improved mitochondrial function, improved neuronal function in the brain, and more. Here, we look at the science behind NMN, its stability, possible pharmacokinetics, transport, function, and ability to induce biosynthesis of NAD+.15 Supplementing NMN may be an effective nutraceutical anti-aging intervention, with beneficial effects on a wide array of physiological functions.16\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003eShade C. The Science Behind NMN-A Stable, Reliable NAD+Activator and Anti-Aging Molecule. Integr Med (Encinitas). 2020 Feb;19(1):12-14. PMID: 32549859; PMCID: PMC7238909. Full article and references available on \u003ca title=\"The Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7238909\/#:~:text=administered%20NMN%20is%20quickly%20synthesized,linked%20changes%20in%20gene%20expression.\" target=\"_blank\"\u003eNational Library of Medicine\u003c\/a\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eFAQ's\u003c\/h5\u003e\n\u003ch2\u003eFAQ's: BioActiv HealthCare NMN\u003c\/h2\u003e\n\u003ch3\u003eWhat is nicotinamide mononucleotide (NMN)?\u003c\/h3\u003e\n\u003cp\u003eNMN is a naturally occurring molecule that helps produce energy in the body.\u003c\/p\u003e\n\u003cp\u003eNMN is a molecule called a nucleotide. Nucleotides have many roles in the body including the production of DNA.\u003c\/p\u003e\n\u003cp\u003eNMN is converted into another molecule within the cells known as nicotinamide adenine dinucleotide (NAD). Your body needs NAD for a variety of functions involved in metabolism and energy production.\u003c\/p\u003e\n\u003cp\u003eThe amount of NAD your body can make depends on the amount of NMN available in your body.\u003c\/p\u003e\n\u003ch3\u003eWhat is the difference between NR, NMN and NAD?\u003c\/h3\u003e\n\u003cp\u003eIn the body, NR (Nicotinamide Riboside) converts to NMN (Nicotinamide Mono Nucleotide) which is then converted in the cell to NAD (Nicotinamide Adenine Dinucleotide).  \u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThe best form to take is NMN (Nicotinamide Mono Nucleotide).\u003c\/p\u003e\n\u003ch3\u003eIs it better to take a supplement containing NMN or NAD?\u003c\/h3\u003e\n\u003cp\u003eResearch has found that taking a supplement containing NMN is better than taking a NAD supplement. This is because NAD is unable to enter the cell because the cells have receptors for NMN but do not have receptors for NAD. So, it is best to take NMN because NMN can enter the cells where it is converted to NAD.\u003c\/p\u003e\n\u003cp\u003eResearchers who study NMN and NAD believe that the goal is to get NAD levels in the cells to levels closer to those levels in our youth.\u003c\/p\u003e\n\u003ch3\u003eWhy is NMN so important?\u003c\/h3\u003e\n\u003cp\u003eAll the cells in your body use NAD and NMN is required to make NAD. \u003c\/p\u003e\n\u003ch3\u003eWhat are the benefits of NAD?\u003c\/h3\u003e\n\u003cp\u003eNAD helps cells regulate a number of essential functions in cells, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eenergy metabolism\u003c\/li\u003e\n\u003cli\u003eDNA repair\u003c\/li\u003e\n\u003cli\u003egene expression\u003c\/li\u003e\n\u003cli\u003ecellular stress responses\u003c\/li\u003e\n\u003cli\u003eoxidative stress\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSufficient NMN is essential to produce enough NAD to support cell functions.\u003c\/p\u003e\n\u003ch3\u003eHow is NMN and NAD related to ageing?\u003c\/h3\u003e\n\u003cp\u003eThe levels of NMN decline naturally as we age, and, as a result, your NAD levels also decline. This contributes to some of the health effects experienced during ageing.\u003c\/p\u003e\n\u003cp\u003eLow levels of NMN and NAD can be involved in conditions including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ediabetes\u003c\/li\u003e\n\u003cli\u003eliver disease\u003c\/li\u003e\n\u003cli\u003ebrain health\u003c\/li\u003e\n\u003cli\u003eheart health\u003c\/li\u003e\n\u003cli\u003elongevity\u003c\/li\u003e\n\u003cli\u003ejet lag\u003c\/li\u003e\n\u003cli\u003emuscle function and strength\u003c\/li\u003e\n\u003cli\u003eendurance\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCan NMN increase longevity?\u003c\/h3\u003e\n\u003cp\u003eIn the cells are proteins called Sirtuins that help repair DNA. Sirtuins are linked to longevity.\u003c\/p\u003e\n\u003ch3\u003eIs NMN safe, and does it have side effects?\u003c\/h3\u003e\n\u003cp\u003eNMN is an ideal supplement to increase cellular levels of NAD. It is well-tolerated, and both human and animal studies have observed it had minimal side effects.\u003c\/p\u003e\n\u003cp\u003eResearch in humans has shown that doses of up to 1,200 mg daily are safe to consume.\u003c\/p\u003e\n\u003ch3\u003eIs NMN in food?\u003cbr\u003e\n\u003c\/h3\u003e\n\u003cp\u003eNMN is found in a variety of foods. Some NMN-rich dietary sources:\u003c\/p\u003e\n\u003cp\u003eavocados - 0.36 to 1.60mg per 100grams\u003c\/p\u003e\n\u003cp\u003ebroccoli - 0.25 to 1.12mg per 100grams\u003c\/p\u003e\n\u003cp\u003ecabbage - up to 0.9mg per 100grams\u003c\/p\u003e\n\u003cp\u003ecucumber -  small amounts\u003c\/p\u003e\n\u003cp\u003ecow’s milk -  small amounts\u003c\/p\u003e\n\u003cp\u003eedamame  -  small amounts\u003c\/p\u003e\n\u003cp\u003etomatoes - 0.26 to 0.30mg per 100grams\u003c\/p\u003e\n\u003cp\u003eraw beef - 0.06 to 0.42mg per 100grams\u003c\/p\u003e\n\u003cp\u003eStudies in mice have found that the gut absorbs NMN readily. More studies are needed to investigate how eating foods containing NMN may increase NAD levels in cells.\u003c\/p\u003e\n\u003ch3\u003eCan NMN  help with ageing?\u003c\/h3\u003e\n\u003cp\u003eNMN and NAD levels naturally decline with age. Researchers have suggested that taking NMN supplements may help with age-related health concerns.\u003c\/p\u003e\n\u003cp\u003eA study in 10 Japanese men found that taking NMN at 100, 250, or 500mg increased levels of NAD. \u003c\/p\u003e\n\u003cp\u003eInsulin resistance can develop as we age and is one of the reasons diabetes is more common in older adults. Although studies haven’t specifically looked at the effects of taking NMN supplements, the research available suggests that it may help you maintain or regain insulin sensitivity with age.\u003c\/p\u003e\n\u003cp\u003eMore studies on these effects in humans are needed to investigate this potential benefit\u003c\/p\u003e\n\u003cp\u003eTaking NMN supplements has also been shown to reduce drowsiness and improve muscle responsiveness in older adults, which may improve both physical and mental health with age.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}