{"id":5548176310430,"title":"Orthoplex Activated B Complex","handle":"orthoplex-green-activated-b-complex-60c","description":"\u003ch2\u003eOrthoplex Activated B Complex 60caps\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eB Vitamins in Activated Forms\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eOrthoplex Green (previously Orthoplex Blue)\u003c\/p\u003e\n\u003cp\u003eSize: 60 capsules\u003c\/p\u003e\n\u003cp\u003eOrthoplex Activated B Complex Summary:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOrthoplex Green Activated B Complex is a comprehensive B-Complex formula providing active B vitamin forms for optimal utilisation.\u003c\/li\u003e\n\u003cli\u003eOffers pyridoxal 5-phosphate, riboflavin sodium phosphate and folinic acid, as well as inositol, choline, and all the B vitamins.\u003c\/li\u003e\n\u003cli\u003eOrthoplex Green Activated B Complex supports overall wellbeing, especially during times of stress when nutrient needs are increased.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003eGluten Free, Dairy Free, Soy Protein Free\u003c\/p\u003e\n\u003cp\u003eVegan and Vegetarian Friendly\u003c\/p\u003e\n\u003cp\u003eOrthoplex Activated B Complex AUST L 311676\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eAdults\u003c\/p\u003e\n\u003cp\u003eTake 1 capsule daily with meals, or as recommended by your registered healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eindications\u003c\/h5\u003e\n\u003ch2\u003eIndications: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports general health and wellbeing\u003c\/li\u003e\n\u003cli\u003eHelps maintain normal blood health\u003c\/li\u003e\n\u003cli\u003eSupports a healthy stress response in the body\u003c\/li\u003e\n\u003cli\u003eAids metabolism of sugar and carbohydrates\u003c\/li\u003e\n\u003cli\u003eMaintains cardiovascular and immune system health\u003c\/li\u003e\n\u003cli\u003eSupports neurotransmitter synthesis and nervous system health and function\u003c\/li\u003e\n\u003cli\u003eSupports skin health and hair growth in healthy individuals\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eTechnical Information\u003c\/h5\u003e\n\u003ch2\u003eTechnical Information: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eBeneficial During Times of Stress\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eBiologically active forms of Vitamin B6 (Pyridoxal 5-Phosphate), Folic Acid (Folinic Acid) and Vitamin B2 (Riboflavin 5-Phosphate), can bypass the enzymatic processes in the body that lead to the active nutrient forms, and may therefore produce more significant results.\u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003eResearch has identified genetic differences in the activity of certain biologic enzymes, with some individuals exhibiting the potential inability to intrinsically activate, and therefore utilise, non-active forms of B vitamins.1,2\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003eFolinic Acid bypasses the deconjugation and reduction steps required for Folic Acid use in the body. Folinic Acid has been deemed to be a more metabolically active form of Folate, and is believed to be capable of elevating Folate coenzyme levels in circumstances where Folic Acid supplementation fails. It has been suggested that Folinic Acid is more readily transported through the blood-brain-barrier into the central nervous system, and has a longer half life in the body than Folic Acid.3\u003c\/p\u003e\n\u003cp\u003eThe active form of vitamin B6 – Pyridoxal 5-Phosphate – is a cofactor for the activity of a number of enzymes involved in metabolism.4 Riboflavin 5-Phosphate is the active form of Vitamin B2, which is an essential component of the electron transport chain, energy production and many other metabolic processes.5\u003c\/p\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_Blue_Activated_B_Complex_60c_Figure_1_10_off_RRP_at_HealthMasters_600x600.jpg?v=1596786494\" alt=\"Orthoplex Blue Activated B Complex 60c Figure 1 10% off RRP at HealthMasters\" style=\"float: none;\" width=\"610\" height=\"610\"\u003e\u003c\/div\u003e\n\u003ch3\u003e\u003cem\u003eBeneficial During Times of Stress\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eDuring periods of intense stress, there is an increased requirement for water-soluble B vitamins.6-8 This demand may be intensified by stress-induced impairment of digestive function9-11 and reduced local parasympathetic nervous system activity.12 B vitamins support the body’s response to stress by supporting the respective body systems and overall nutrient status.13\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eAids, Assists or Helps in the Maintenance of General Well-Being\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eAs an exercise,8 illness14-16 and psychological stress6,7 tax metabolic pathways that depend on B vitamins such as Thiamine, Riboflavin and Pyridoxine, the requirements for these vitamins may be increased in stressed, active, or recovering individuals.\u003c\/p\u003e\n\u003cp\u003eWhen viewing the Citric Acid Cycle (Figure 1), it is evident how vital the B group vitamins are as cofactors for the function of this pathway. If the body is deficient in any of these integral nutrients due to poor supply, reduced absorption or increased demand, it is clear how energy production and well-being may be compromised.17-21\u003c\/p\u003e\n\u003cp\u003eThiamine serves as a cofactor for several enzymes involved in carbohydrate catabolism, including pyruvate dehydrogenase, transketolase, alpha-ketoglutarate, as well as amino acid catabolism.22\u003c\/p\u003e\n\u003cp\u003eTwo fundamental co-enzymes of the Citric Acid Cycle – flavinadenine dinucleotide (FAD) and flavin mononucleotide (FMN) (Riboflavin 5-Phosphate) – are both important for the body’s production of adenosine triphosphate and rely upon Vitamin B2 as a cofactor.23 The activated form of Vitamin B2 bypasses a biochemical step24 and may offer more efficient support for energy production.\u003c\/p\u003e\n\u003cp\u003eNiacin is involved in numerous biological functions and is a precursor for the coenzymes nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide hydrogen (NADH), which are involved in a number of metabolic functions.25,26\u003c\/p\u003e\n\u003cp\u003eVitamin B5 (Pantothenic Acid) is required for coenzyme A synthesis – an important component of energy storage and release. In conjunction with Thiamine, Riboflavin and Niacin, Vitamin B5 is involved in the oxidative decarboxylation of pyruvate and alpha-ketoglutarate in the Citric Acid Cycle.27\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eReferences available upon request\u003c\/em\u003e\u003c\/p\u003e\n\u003ch5\u003eingredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach capsule contains\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eThiamine hydrochloride\u003c\/td\u003e\n\u003ctd\u003e50.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Thiamine\u003c\/td\u003e\n\u003ctd\u003e44.6mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRiboflavin sodium phosphate\u003c\/td\u003e\n\u003ctd\u003e20.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Riboflavin\u003c\/td\u003e\n\u003ctd\u003e15.2mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNicotinamide\u003c\/td\u003e\n\u003ctd\u003e80.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Vitamin B3\u003c\/td\u003e\n\u003ctd\u003e80.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNicotinic acid\u003c\/td\u003e\n\u003ctd\u003e20.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Vitamin B3\u003c\/td\u003e\n\u003ctd\u003e20.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePyridoxal 5-phosphate monohydrate\u003c\/td\u003e\n\u003ctd\u003e10.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Pyridoxine\u003c\/td\u003e\n\u003ctd\u003e6.38mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePyridoxine hydrochloride\u003c\/td\u003e\n\u003ctd\u003e20.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Pyridoxine\u003c\/td\u003e\n\u003ctd\u003e16.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalcium pantothenate\u003c\/td\u003e\n\u003ctd\u003e164.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Pantothenic acid\u003c\/td\u003e\n\u003ctd\u003e150.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCholine bitartrate\u003c\/td\u003e\n\u003ctd\u003e100.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInositol\u003c\/td\u003e\n\u003ctd\u003e100.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiotin\u003c\/td\u003e\n\u003ctd\u003e500.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCyanocobalamin\u003c\/td\u003e\n\u003ctd\u003e500.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Vitamin B12\u003c\/td\u003e\n\u003ctd\u003e500.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalcium folinate\u003c\/td\u003e\n\u003ctd\u003e521.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Folinic acid\u003c\/td\u003e\n\u003ctd\u003e400.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eGlycine, leucine, colloidal anhydrous silica, vegetable capsule (Vcaps).\u003c\/p\u003e\n\u003ch5\u003eAllergen Advice\u003c\/h5\u003e\n\u003ch2\u003eAllergen Advice: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eGluten Free, Dairy Free, Soy Protein Free\u003c\/p\u003e\n\u003cp\u003eVegan and Vegetarian Friendly\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eStore below 25°C in a cool, dry place, away from direct sunlight.\u003c\/p\u003e\n\u003ch5\u003eWarning\u003c\/h5\u003e\n\u003ch2\u003eWarning: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eIf pregnant or likely to become pregnant, consult a pharmacist or a doctor before use. Contains nicotinic acid which may cause flushing. \u003c\/p\u003e\n\u003cp\u003eVitamin supplements should not replace a balanced diet. If symptoms persist, seek the advice of a healthcare professional.\u003c\/p\u003e\n\u003ch5\u003eCompanion Products\u003c\/h5\u003e\n\u003ch2\u003eCompanion Products: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eYou may also be interested in:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOrthoplex MagPlex\u003c\/li\u003e\n\u003cli\u003eOrthoplex Iron   \u003c\/li\u003e\n\u003cli\u003eOrthoplex PreDop Lift\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eOrthoplex Green Range\u003c\/h5\u003e\n\u003ch2\u003eOrthoplex Green Range\u003c\/h2\u003e\n\u003cp\u003eThe Orthoplex Green range was developed by nutritional biochemist Henry Osiecki over 30 years ago. Henry is an award-winning biochemist who, after years in clinic, developed the Orthoplex range of Naturopathic Medicines. The Orthoplex range is known for being the first to market with new formulations, incorporating the latest in clinical research.\u003c\/p\u003e\n\u003cp\u003e\"I am impressed with the quality and effectiveness of Orthoplex products. I have prescribed Orthoplex products to my patients for over 30 years. Orthoplex products have assisted me in successfully helping many 1000's of patients to better health.\"\u003c\/p\u003e\n\u003cp\u003eHealthMasters Naturopath Kevin Tresize ND\u003c\/p\u003e\n\u003cp\u003eSince day one, Bio Concepts has been committed to providing the highest quality products, with absolute transparency and disclosure of all excipients, believing every component is important when it comes to effective treatment.\u003c\/p\u003e\n\u003cp\u003eIn his clinical years, Henry's approach to treatment plans was that they must always be tailored to the individual. As such, Bio Concepts formulations have always focused on providing the correct dosage for specific biochemical pathways, rather than just delivering the largest dose possible.\u003c\/p\u003e\n\u003cp\u003eHenry has written university courses, several books and scientific papers, and is the founder of the Bio Concepts Education Centre.\u003c\/p\u003e\n\u003cp\u003eOrthoplex Green is a practitioner supplement range and should be taken according to the recommendation of a qualified practitioner.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2022-10-11T15:59:56+11:00","created_at":"2020-08-07T16:11:32+10:00","vendor":"Orthoplex","type":"Orthoplex Green 10% off RRP","tags":["Naturopathic","Orthoplex Blue","Orthoplex Green","PB"],"price":4136,"price_min":4136,"price_max":4136,"available":true,"price_varies":false,"compare_at_price":4595,"compare_at_price_min":4595,"compare_at_price_max":4595,"compare_at_price_varies":false,"variants":[{"id":35556247732382,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"OpxActdBComplex60C","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Orthoplex Activated B Complex","public_title":null,"options":["Default Title"],"price":4136,"weight":0,"compare_at_price":4595,"inventory_quantity":19898,"inventory_management":"shopify","inventory_policy":"deny","barcode":"9319091979579","requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexGreenActivatedBComplex60caps10_offRRPatHealthMastersOrthoplexGreen.jpg?v=1646908026","\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexGreen10_offRRPHealthMastersOrthoplexGreen_7a9666b3-0d43-4637-8765-44ba15bca5a5.jpg?v=1646908026"],"featured_image":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexGreenActivatedBComplex60caps10_offRRPatHealthMastersOrthoplexGreen.jpg?v=1646908026","options":["Title"],"media":[{"alt":"Orthoplex Activated B Complex 60caps 10% off RRP at HealthMasters Orthoplex Green","id":29089961246950,"position":1,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexGreenActivatedBComplex60caps10_offRRPatHealthMastersOrthoplexGreen.jpg?v=1646908026"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexGreenActivatedBComplex60caps10_offRRPatHealthMastersOrthoplexGreen.jpg?v=1646908026","width":1200},{"alt":"Orthoplex Activated B Complex 10% off RRP at HealthMasters Orthoplex Green Logo","id":29089962852582,"position":2,"preview_image":{"aspect_ratio":0.776,"height":500,"width":388,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexGreen10_offRRPHealthMastersOrthoplexGreen_7a9666b3-0d43-4637-8765-44ba15bca5a5.jpg?v=1646908026"},"aspect_ratio":0.776,"height":500,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/OrthoplexGreen10_offRRPHealthMastersOrthoplexGreen_7a9666b3-0d43-4637-8765-44ba15bca5a5.jpg?v=1646908026","width":388}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch2\u003eOrthoplex Activated B Complex 60caps\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eB Vitamins in Activated Forms\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eOrthoplex Green (previously Orthoplex Blue)\u003c\/p\u003e\n\u003cp\u003eSize: 60 capsules\u003c\/p\u003e\n\u003cp\u003eOrthoplex Activated B Complex Summary:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOrthoplex Green Activated B Complex is a comprehensive B-Complex formula providing active B vitamin forms for optimal utilisation.\u003c\/li\u003e\n\u003cli\u003eOffers pyridoxal 5-phosphate, riboflavin sodium phosphate and folinic acid, as well as inositol, choline, and all the B vitamins.\u003c\/li\u003e\n\u003cli\u003eOrthoplex Green Activated B Complex supports overall wellbeing, especially during times of stress when nutrient needs are increased.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003eGluten Free, Dairy Free, Soy Protein Free\u003c\/p\u003e\n\u003cp\u003eVegan and Vegetarian Friendly\u003c\/p\u003e\n\u003cp\u003eOrthoplex Activated B Complex AUST L 311676\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eAdults\u003c\/p\u003e\n\u003cp\u003eTake 1 capsule daily with meals, or as recommended by your registered healthcare practitioner.\u003c\/p\u003e\n\u003ch5\u003eindications\u003c\/h5\u003e\n\u003ch2\u003eIndications: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports general health and wellbeing\u003c\/li\u003e\n\u003cli\u003eHelps maintain normal blood health\u003c\/li\u003e\n\u003cli\u003eSupports a healthy stress response in the body\u003c\/li\u003e\n\u003cli\u003eAids metabolism of sugar and carbohydrates\u003c\/li\u003e\n\u003cli\u003eMaintains cardiovascular and immune system health\u003c\/li\u003e\n\u003cli\u003eSupports neurotransmitter synthesis and nervous system health and function\u003c\/li\u003e\n\u003cli\u003eSupports skin health and hair growth in healthy individuals\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eTechnical Information\u003c\/h5\u003e\n\u003ch2\u003eTechnical Information: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eBeneficial During Times of Stress\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eBiologically active forms of Vitamin B6 (Pyridoxal 5-Phosphate), Folic Acid (Folinic Acid) and Vitamin B2 (Riboflavin 5-Phosphate), can bypass the enzymatic processes in the body that lead to the active nutrient forms, and may therefore produce more significant results.\u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003eResearch has identified genetic differences in the activity of certain biologic enzymes, with some individuals exhibiting the potential inability to intrinsically activate, and therefore utilise, non-active forms of B vitamins.1,2\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003eFolinic Acid bypasses the deconjugation and reduction steps required for Folic Acid use in the body. Folinic Acid has been deemed to be a more metabolically active form of Folate, and is believed to be capable of elevating Folate coenzyme levels in circumstances where Folic Acid supplementation fails. It has been suggested that Folinic Acid is more readily transported through the blood-brain-barrier into the central nervous system, and has a longer half life in the body than Folic Acid.3\u003c\/p\u003e\n\u003cp\u003eThe active form of vitamin B6 – Pyridoxal 5-Phosphate – is a cofactor for the activity of a number of enzymes involved in metabolism.4 Riboflavin 5-Phosphate is the active form of Vitamin B2, which is an essential component of the electron transport chain, energy production and many other metabolic processes.5\u003c\/p\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/files\/Orthoplex_Blue_Activated_B_Complex_60c_Figure_1_10_off_RRP_at_HealthMasters_600x600.jpg?v=1596786494\" alt=\"Orthoplex Blue Activated B Complex 60c Figure 1 10% off RRP at HealthMasters\" style=\"float: none;\" width=\"610\" height=\"610\"\u003e\u003c\/div\u003e\n\u003ch3\u003e\u003cem\u003eBeneficial During Times of Stress\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eDuring periods of intense stress, there is an increased requirement for water-soluble B vitamins.6-8 This demand may be intensified by stress-induced impairment of digestive function9-11 and reduced local parasympathetic nervous system activity.12 B vitamins support the body’s response to stress by supporting the respective body systems and overall nutrient status.13\u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eAids, Assists or Helps in the Maintenance of General Well-Being\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eAs an exercise,8 illness14-16 and psychological stress6,7 tax metabolic pathways that depend on B vitamins such as Thiamine, Riboflavin and Pyridoxine, the requirements for these vitamins may be increased in stressed, active, or recovering individuals.\u003c\/p\u003e\n\u003cp\u003eWhen viewing the Citric Acid Cycle (Figure 1), it is evident how vital the B group vitamins are as cofactors for the function of this pathway. If the body is deficient in any of these integral nutrients due to poor supply, reduced absorption or increased demand, it is clear how energy production and well-being may be compromised.17-21\u003c\/p\u003e\n\u003cp\u003eThiamine serves as a cofactor for several enzymes involved in carbohydrate catabolism, including pyruvate dehydrogenase, transketolase, alpha-ketoglutarate, as well as amino acid catabolism.22\u003c\/p\u003e\n\u003cp\u003eTwo fundamental co-enzymes of the Citric Acid Cycle – flavinadenine dinucleotide (FAD) and flavin mononucleotide (FMN) (Riboflavin 5-Phosphate) – are both important for the body’s production of adenosine triphosphate and rely upon Vitamin B2 as a cofactor.23 The activated form of Vitamin B2 bypasses a biochemical step24 and may offer more efficient support for energy production.\u003c\/p\u003e\n\u003cp\u003eNiacin is involved in numerous biological functions and is a precursor for the coenzymes nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide hydrogen (NADH), which are involved in a number of metabolic functions.25,26\u003c\/p\u003e\n\u003cp\u003eVitamin B5 (Pantothenic Acid) is required for coenzyme A synthesis – an important component of energy storage and release. In conjunction with Thiamine, Riboflavin and Niacin, Vitamin B5 is involved in the oxidative decarboxylation of pyruvate and alpha-ketoglutarate in the Citric Acid Cycle.27\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eReferences available upon request\u003c\/em\u003e\u003c\/p\u003e\n\u003ch5\u003eingredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach capsule contains\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eThiamine hydrochloride\u003c\/td\u003e\n\u003ctd\u003e50.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Thiamine\u003c\/td\u003e\n\u003ctd\u003e44.6mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRiboflavin sodium phosphate\u003c\/td\u003e\n\u003ctd\u003e20.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Riboflavin\u003c\/td\u003e\n\u003ctd\u003e15.2mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNicotinamide\u003c\/td\u003e\n\u003ctd\u003e80.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Vitamin B3\u003c\/td\u003e\n\u003ctd\u003e80.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNicotinic acid\u003c\/td\u003e\n\u003ctd\u003e20.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Vitamin B3\u003c\/td\u003e\n\u003ctd\u003e20.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePyridoxal 5-phosphate monohydrate\u003c\/td\u003e\n\u003ctd\u003e10.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Pyridoxine\u003c\/td\u003e\n\u003ctd\u003e6.38mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePyridoxine hydrochloride\u003c\/td\u003e\n\u003ctd\u003e20.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Pyridoxine\u003c\/td\u003e\n\u003ctd\u003e16.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalcium pantothenate\u003c\/td\u003e\n\u003ctd\u003e164.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Pantothenic acid\u003c\/td\u003e\n\u003ctd\u003e150.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCholine bitartrate\u003c\/td\u003e\n\u003ctd\u003e100.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInositol\u003c\/td\u003e\n\u003ctd\u003e100.0mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiotin\u003c\/td\u003e\n\u003ctd\u003e500.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCyanocobalamin\u003c\/td\u003e\n\u003ctd\u003e500.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Vitamin B12\u003c\/td\u003e\n\u003ctd\u003e500.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalcium folinate\u003c\/td\u003e\n\u003ctd\u003e521.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Folinic acid\u003c\/td\u003e\n\u003ctd\u003e400.0mcg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eGlycine, leucine, colloidal anhydrous silica, vegetable capsule (Vcaps).\u003c\/p\u003e\n\u003ch5\u003eAllergen Advice\u003c\/h5\u003e\n\u003ch2\u003eAllergen Advice: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eGluten Free, Dairy Free, Soy Protein Free\u003c\/p\u003e\n\u003cp\u003eVegan and Vegetarian Friendly\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eStore below 25°C in a cool, dry place, away from direct sunlight.\u003c\/p\u003e\n\u003ch5\u003eWarning\u003c\/h5\u003e\n\u003ch2\u003eWarning: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eIf pregnant or likely to become pregnant, consult a pharmacist or a doctor before use. Contains nicotinic acid which may cause flushing. \u003c\/p\u003e\n\u003cp\u003eVitamin supplements should not replace a balanced diet. If symptoms persist, seek the advice of a healthcare professional.\u003c\/p\u003e\n\u003ch5\u003eCompanion Products\u003c\/h5\u003e\n\u003ch2\u003eCompanion Products: Orthoplex Activated B Complex\u003c\/h2\u003e\n\u003cp\u003eYou may also be interested in:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOrthoplex MagPlex\u003c\/li\u003e\n\u003cli\u003eOrthoplex Iron   \u003c\/li\u003e\n\u003cli\u003eOrthoplex PreDop Lift\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eOrthoplex Green Range\u003c\/h5\u003e\n\u003ch2\u003eOrthoplex Green Range\u003c\/h2\u003e\n\u003cp\u003eThe Orthoplex Green range was developed by nutritional biochemist Henry Osiecki over 30 years ago. Henry is an award-winning biochemist who, after years in clinic, developed the Orthoplex range of Naturopathic Medicines. The Orthoplex range is known for being the first to market with new formulations, incorporating the latest in clinical research.\u003c\/p\u003e\n\u003cp\u003e\"I am impressed with the quality and effectiveness of Orthoplex products. I have prescribed Orthoplex products to my patients for over 30 years. Orthoplex products have assisted me in successfully helping many 1000's of patients to better health.\"\u003c\/p\u003e\n\u003cp\u003eHealthMasters Naturopath Kevin Tresize ND\u003c\/p\u003e\n\u003cp\u003eSince day one, Bio Concepts has been committed to providing the highest quality products, with absolute transparency and disclosure of all excipients, believing every component is important when it comes to effective treatment.\u003c\/p\u003e\n\u003cp\u003eIn his clinical years, Henry's approach to treatment plans was that they must always be tailored to the individual. As such, Bio Concepts formulations have always focused on providing the correct dosage for specific biochemical pathways, rather than just delivering the largest dose possible.\u003c\/p\u003e\n\u003cp\u003eHenry has written university courses, several books and scientific papers, and is the founder of the Bio Concepts Education Centre.\u003c\/p\u003e\n\u003cp\u003eOrthoplex Green is a practitioner supplement range and should be taken according to the recommendation of a qualified practitioner.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}