{"id":9296349835,"title":"Metagenics NeuroCalm Sleep 30 tablets","handle":"metagenics-neurocalm-sleep-30tabs","description":"\u003ch2\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/buy-naturopathic-products\" title=\"Buy Naturopathic Products 10% off RRP\"\u003e\u003cspan style=\"color: #eeeeee; background-color: #0b5394;\"\u003e  Buy Naturopathic Products 10% off RRP - Click Here  \u003c\/span\u003e\u003c\/a\u003e\u003c\/h2\u003e\n\u003ch2\u003e\u003cstrong\u003eMetagenics NeuroCalm Sleep For Insomnia And Mild Anxiety\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch2\u003eMetagenics NeuroCalm Sleep 30 tablets\u003c\/h2\u003e\n\u003cp\u003eIngredients in Metagenics NeuroCalm Sleep have been clinically shown or traditionally used:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFor insomnia - for a restful sleep, to get to sleep faster and stay asleep longer.\u003csup\u003e1,2,3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eTo relieve mild anxiety, tension and worry.\u003csup\u003e4,5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eFast acting, high strength, non-habit forming herbs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor more information go to:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/metagenics-neurocalm-sleep-review\" target=\"_blank\" title=\"Metagenics NeuroCalm Sleep Review | HealthMasters\" rel=\"noopener noreferrer\"\u003eMetagenics NeuroCalm Sleep Review\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/collections\/metagenics-neurocalm\" title=\"Metagenics NeuroCalm and Metagenics NeuroCalm Sleep Comparison | HealthMasters\"\u003eMetagenics NeuroCalm and Metagenics NeuroCalm Sleep Comparison\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDirections\u003c\/h5\u003e\n\u003ch2\u003eDirections: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eAdults:\u003c\/p\u003e\n\u003cp\u003eFor mild anxiety: Take 1 tablet twice daily with food.\u003c\/p\u003e\n\u003cp\u003eFor insomnia: Take 2 tablets once daily with your evening meal.\u003c\/p\u003e\n\u003ch5\u003eBenefits\u003c\/h5\u003e\n\u003ch2\u003eClinical Benefits: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroCalm Sleep has sedative qualities which relieve insomnia and mild anxiety.\u003c\/strong\u003e California poppy has traditionally been used for its sedating effects, therefore contributing to a calm and restful sleep.\u003csup\u003e6\u003c\/sup\u003e Animal studies have suggested this sedative effect may be due to its ability to bind to GABA receptors and activate them.6Lavender oil also acts via GABA receptors and provides additional calming effects by moderating production of stress hormones such as adrenocorticotropic hormone (ACTH), which stimulates cortisol production.\u003csup\u003e7,8\u003c\/sup\u003e Passion flower has an anxiolytic effect by affecting GABA neurotransmitter pathways.\u003csup\u003e9\u003c\/sup\u003e Flavonoids from passion flower bind to the stress receptor sites of the GABAA receptor.\u003csup\u003e10\u003c\/sup\u003e Zizyphus’ calming effects come from its ability to increase the effect of GABA.\u003csup\u003e11\u003c\/sup\u003e GABA is a calming neurotransmitter and its activity promotes sleepiness and relaxation.\u003csup\u003e12\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroCalm Sleep reduces effects of excitatory neurotransmitters.\u003c\/strong\u003e Linalool from lavender oil inhibits acetylcholine release and glutamate binding in the cerebral cortex.\u003csup\u003e13\u003c\/sup\u003e Its ability to ease tension and promote a restful sleep come from this ability to alter excitatory neurotransmitters such as glutamate and noradrenaline.\u003csup\u003e14\u003c\/sup\u003e Zizyphus also reduces the neuroexcitatory effects of glutamate thus reducing wakefulness and alertness.\u003csup\u003e15,16\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eEach tablet contains:\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eExtracts equivalent to:\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZiziphus jujuba var. spinosa, seed dry (Zizyphus)\u003c\/td\u003e\n\u003ctd\u003e5.0g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePassiflora incarnata, herb dry (Passion flower)\u003c\/td\u003e\n\u003ctd\u003e2.0g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEschscholzia californica, herb flowering dry (California poppy)\u003c\/td\u003e\n\u003ctd\u003e750mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePiscidia piscipula, root bark dry (Jamaica dogwood)\u003c\/td\u003e\n\u003ctd\u003e750mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLavender Oil\u003c\/td\u003e\n\u003ctd\u003e40mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eMetagenics NeuroCalm Sleep is free from animal products, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast and soy protein. Metagenics NeuroCalm Sleep is free from artificial colours, flavours and preservatives.\u003c\/p\u003e\n\u003ch5\u003eFree Froms\u003c\/h5\u003e\n\u003ch2\u003eFree Froms: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eMetagenics NeuroCalm Sleep is free from animal products, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast and soy protein. Metagenics NeuroCalm Sleep is free from artificial colours, flavours and preservatives.\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eAntidepressant medications: Zizyphus, California poppy and lavender may have additive effects, however beneficial interaction is likely under professional supervision. Monitor, and do not exceed recommended dosage.\u003c\/p\u003e\n\u003cp\u003eBarbiturates: Magnolia and passionflower might increase the risk of drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle, or if involved in activities requiring mental alertness.\u003c\/p\u003e\n\u003cp\u003eBenzodiazepines and CNS depressants: California poppy and zizyphus may have additive sedative effects. Exercise caution if operating heavy machinery, driving a motor vehicle, or if involved in activities requiring mental alertness. Monitor, and do not exceed recommended dose.\u003c\/p\u003e\n\u003cp\u003eDiarrhoea: Zizyphus may exacerbate diarrhoea. Use with caution in people with severe diarrhoea.\u003c\/p\u003e\n\u003cp\u003eSurgery: Due to CNS depressant effects and theoretical additive effects with anaesthesia or sedatives, it has been recommended that sedative herbs, such as California poppy, passionflower and lavender, should be discontinued at least 2 weeks before elective surgical procedures.\u003c\/p\u003e\n\u003cp\u003eFor full details, references or more information contact HealthMasters in Australia by email: reception@healthmasters.com.au\u003c\/p\u003e\n\u003ch5\u003eContraindications\u003c\/h5\u003e\n\u003ch2\u003eContraindications: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eAllergies and Sensitivities: Avoid in patients with known allergy\/hypersensitivity to Zizyphus spp., its constituents, or members of the family Rhamnaceae (buckthorn) and Jamaican dogwood and\/or members of the Fabaceae family.\u003c\/p\u003e\n\u003cp\u003eSome components of some zizyphus species may cross react with latex IgE; those with severe latex allergy may react to zizyphus fruits.\u003c\/p\u003e\n\u003ch5\u003ePregnancy and Lactation\u003c\/h5\u003e\n\u003ch2\u003ePregnancy and Lactation: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003ePregnancy:\u003c\/strong\u003e Contraindicated in pregnancy. Lavender has been found to stimulate uterine contractions in an animal model. Zizyphus may also have uterine-stimulating activity. Avoid use during pregnancy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBreastfeeding:\u003c\/strong\u003e Appropriate for use at recommended dosages.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e \u003ca href=\"https:\/\/shop.healthmasters.com.au\/search?q=CalmX\" title=\"Metagenics CalmX 10% off RRP | HealthMasters\"\u003eMetagenics CalmX\u003c\/a\u003e is safe to use in pregnancy and breastfeeding and can be recommended as an alternative to NeuroCalm.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eStore below 30° C\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2017-06-29T17:41:21+10:00","created_at":"2017-06-29T17:41:21+10:00","vendor":"Metagenics","type":"Buy Naturopathic Products 10% off RRP","tags":["Anxiety","Insomnia","Metagenics","Stress and Mood"],"price":2696,"price_min":2696,"price_max":2696,"available":true,"price_varies":false,"compare_at_price":2995,"compare_at_price_min":2995,"compare_at_price_max":2995,"compare_at_price_varies":false,"variants":[{"id":33461936587,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"NeuroCalmSleep30tabs","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Metagenics NeuroCalm Sleep 30 tablets","public_title":null,"options":["Default Title"],"price":2696,"weight":140,"compare_at_price":2995,"inventory_quantity":9963,"inventory_management":"shopify","inventory_policy":"deny","barcode":"9315771006412"}],"images":["\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/products\/Metagenics_NeuroCalm_Sleep_30_tabs_10_off_RRP_at_HealthMasters.jpg?v=1554095683","\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/products\/Metagenics_NeuroCalm_Sleep_30_tablets_10_off_RRP_at_HealthMasters.jpg?v=1567062298"],"featured_image":"\/\/cdn.shopify.com\/s\/files\/1\/2075\/8503\/products\/Metagenics_NeuroCalm_Sleep_30_tabs_10_off_RRP_at_HealthMasters.jpg?v=1554095683","options":["Title"],"content":"\u003ch2\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/buy-naturopathic-products\" title=\"Buy Naturopathic Products 10% off RRP\"\u003e\u003cspan style=\"color: #eeeeee; background-color: #0b5394;\"\u003e  Buy Naturopathic Products 10% off RRP - Click Here  \u003c\/span\u003e\u003c\/a\u003e\u003c\/h2\u003e\n\u003ch2\u003e\u003cstrong\u003eMetagenics NeuroCalm Sleep For Insomnia And Mild Anxiety\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch2\u003eMetagenics NeuroCalm Sleep 30 tablets\u003c\/h2\u003e\n\u003cp\u003eIngredients in Metagenics NeuroCalm Sleep have been clinically shown or traditionally used:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFor insomnia - for a restful sleep, to get to sleep faster and stay asleep longer.\u003csup\u003e1,2,3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eTo relieve mild anxiety, tension and worry.\u003csup\u003e4,5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eFast acting, high strength, non-habit forming herbs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor more information go to:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/pages\/metagenics-neurocalm-sleep-review\" target=\"_blank\" title=\"Metagenics NeuroCalm Sleep Review | HealthMasters\" rel=\"noopener noreferrer\"\u003eMetagenics NeuroCalm Sleep Review\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/collections\/metagenics-neurocalm\" title=\"Metagenics NeuroCalm and Metagenics NeuroCalm Sleep Comparison | HealthMasters\"\u003eMetagenics NeuroCalm and Metagenics NeuroCalm Sleep Comparison\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDirections\u003c\/h5\u003e\n\u003ch2\u003eDirections: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eAdults:\u003c\/p\u003e\n\u003cp\u003eFor mild anxiety: Take 1 tablet twice daily with food.\u003c\/p\u003e\n\u003cp\u003eFor insomnia: Take 2 tablets once daily with your evening meal.\u003c\/p\u003e\n\u003ch5\u003eBenefits\u003c\/h5\u003e\n\u003ch2\u003eClinical Benefits: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroCalm Sleep has sedative qualities which relieve insomnia and mild anxiety.\u003c\/strong\u003e California poppy has traditionally been used for its sedating effects, therefore contributing to a calm and restful sleep.\u003csup\u003e6\u003c\/sup\u003e Animal studies have suggested this sedative effect may be due to its ability to bind to GABA receptors and activate them.6Lavender oil also acts via GABA receptors and provides additional calming effects by moderating production of stress hormones such as adrenocorticotropic hormone (ACTH), which stimulates cortisol production.\u003csup\u003e7,8\u003c\/sup\u003e Passion flower has an anxiolytic effect by affecting GABA neurotransmitter pathways.\u003csup\u003e9\u003c\/sup\u003e Flavonoids from passion flower bind to the stress receptor sites of the GABAA receptor.\u003csup\u003e10\u003c\/sup\u003e Zizyphus’ calming effects come from its ability to increase the effect of GABA.\u003csup\u003e11\u003c\/sup\u003e GABA is a calming neurotransmitter and its activity promotes sleepiness and relaxation.\u003csup\u003e12\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroCalm Sleep reduces effects of excitatory neurotransmitters.\u003c\/strong\u003e Linalool from lavender oil inhibits acetylcholine release and glutamate binding in the cerebral cortex.\u003csup\u003e13\u003c\/sup\u003e Its ability to ease tension and promote a restful sleep come from this ability to alter excitatory neurotransmitters such as glutamate and noradrenaline.\u003csup\u003e14\u003c\/sup\u003e Zizyphus also reduces the neuroexcitatory effects of glutamate thus reducing wakefulness and alertness.\u003csup\u003e15,16\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eEach tablet contains:\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eExtracts equivalent to:\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZiziphus jujuba var. spinosa, seed dry (Zizyphus)\u003c\/td\u003e\n\u003ctd\u003e5.0g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePassiflora incarnata, herb dry (Passion flower)\u003c\/td\u003e\n\u003ctd\u003e2.0g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEschscholzia californica, herb flowering dry (California poppy)\u003c\/td\u003e\n\u003ctd\u003e750mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePiscidia piscipula, root bark dry (Jamaica dogwood)\u003c\/td\u003e\n\u003ctd\u003e750mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLavender Oil\u003c\/td\u003e\n\u003ctd\u003e40mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eMetagenics NeuroCalm Sleep is free from animal products, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast and soy protein. Metagenics NeuroCalm Sleep is free from artificial colours, flavours and preservatives.\u003c\/p\u003e\n\u003ch5\u003eFree Froms\u003c\/h5\u003e\n\u003ch2\u003eFree Froms: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eMetagenics NeuroCalm Sleep is free from animal products, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast and soy protein. Metagenics NeuroCalm Sleep is free from artificial colours, flavours and preservatives.\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eAntidepressant medications: Zizyphus, California poppy and lavender may have additive effects, however beneficial interaction is likely under professional supervision. Monitor, and do not exceed recommended dosage.\u003c\/p\u003e\n\u003cp\u003eBarbiturates: Magnolia and passionflower might increase the risk of drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle, or if involved in activities requiring mental alertness.\u003c\/p\u003e\n\u003cp\u003eBenzodiazepines and CNS depressants: California poppy and zizyphus may have additive sedative effects. Exercise caution if operating heavy machinery, driving a motor vehicle, or if involved in activities requiring mental alertness. Monitor, and do not exceed recommended dose.\u003c\/p\u003e\n\u003cp\u003eDiarrhoea: Zizyphus may exacerbate diarrhoea. Use with caution in people with severe diarrhoea.\u003c\/p\u003e\n\u003cp\u003eSurgery: Due to CNS depressant effects and theoretical additive effects with anaesthesia or sedatives, it has been recommended that sedative herbs, such as California poppy, passionflower and lavender, should be discontinued at least 2 weeks before elective surgical procedures.\u003c\/p\u003e\n\u003cp\u003eFor full details, references or more information contact HealthMasters in Australia by email: reception@healthmasters.com.au\u003c\/p\u003e\n\u003ch5\u003eContraindications\u003c\/h5\u003e\n\u003ch2\u003eContraindications: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eAllergies and Sensitivities: Avoid in patients with known allergy\/hypersensitivity to Zizyphus spp., its constituents, or members of the family Rhamnaceae (buckthorn) and Jamaican dogwood and\/or members of the Fabaceae family.\u003c\/p\u003e\n\u003cp\u003eSome components of some zizyphus species may cross react with latex IgE; those with severe latex allergy may react to zizyphus fruits.\u003c\/p\u003e\n\u003ch5\u003ePregnancy and Lactation\u003c\/h5\u003e\n\u003ch2\u003ePregnancy and Lactation: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003ePregnancy:\u003c\/strong\u003e Contraindicated in pregnancy. Lavender has been found to stimulate uterine contractions in an animal model. Zizyphus may also have uterine-stimulating activity. Avoid use during pregnancy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBreastfeeding:\u003c\/strong\u003e Appropriate for use at recommended dosages.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e \u003ca href=\"https:\/\/shop.healthmasters.com.au\/search?q=CalmX\" title=\"Metagenics CalmX 10% off RRP | HealthMasters\"\u003eMetagenics CalmX\u003c\/a\u003e is safe to use in pregnancy and breastfeeding and can be recommended as an alternative to NeuroCalm.\u003c\/p\u003e\n\u003ch5\u003eStorage\u003c\/h5\u003e\n\u003ch2\u003eStorage: Metagenics NeuroCalm Sleep\u003c\/h2\u003e\n\u003cp\u003eStore below 30° C\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}

Metagenics NeuroCalm Sleep 30 tablets

Product Description
Maximum quantity available reached.

  Buy Naturopathic Products 10% off RRP - Click Here  

Metagenics NeuroCalm Sleep For Insomnia And Mild Anxiety

Metagenics NeuroCalm Sleep 30 tablets

Ingredients in Metagenics NeuroCalm Sleep have been clinically shown or traditionally used:

  • For insomnia - for a restful sleep, to get to sleep faster and stay asleep longer.1,2,3
  • To relieve mild anxiety, tension and worry.4,5
  • Fast acting, high strength, non-habit forming herbs.

For more information go to:

Metagenics NeuroCalm Sleep Review

Metagenics NeuroCalm and Metagenics NeuroCalm Sleep Comparison

Directions: Metagenics NeuroCalm Sleep

Adults:

For mild anxiety: Take 1 tablet twice daily with food.

For insomnia: Take 2 tablets once daily with your evening meal.

Clinical Benefits: Metagenics NeuroCalm Sleep

  • NeuroCalm Sleep has sedative qualities which relieve insomnia and mild anxiety. California poppy has traditionally been used for its sedating effects, therefore contributing to a calm and restful sleep.6 Animal studies have suggested this sedative effect may be due to its ability to bind to GABA receptors and activate them.6Lavender oil also acts via GABA receptors and provides additional calming effects by moderating production of stress hormones such as adrenocorticotropic hormone (ACTH), which stimulates cortisol production.7,8 Passion flower has an anxiolytic effect by affecting GABA neurotransmitter pathways.9 Flavonoids from passion flower bind to the stress receptor sites of the GABAA receptor.10 Zizyphus’ calming effects come from its ability to increase the effect of GABA.11 GABA is a calming neurotransmitter and its activity promotes sleepiness and relaxation.12
  • NeuroCalm Sleep reduces effects of excitatory neurotransmitters. Linalool from lavender oil inhibits acetylcholine release and glutamate binding in the cerebral cortex.13 Its ability to ease tension and promote a restful sleep come from this ability to alter excitatory neurotransmitters such as glutamate and noradrenaline.14 Zizyphus also reduces the neuroexcitatory effects of glutamate thus reducing wakefulness and alertness.15,16

Ingredients: Metagenics NeuroCalm Sleep

Each tablet contains:
Extracts equivalent to:
Ziziphus jujuba var. spinosa, seed dry (Zizyphus) 5.0g
Passiflora incarnata, herb dry (Passion flower) 2.0g
Eschscholzia californica, herb flowering dry (California poppy) 750mg
Piscidia piscipula, root bark dry (Jamaica dogwood) 750mg
Lavender Oil 40mg

Metagenics NeuroCalm Sleep is free from animal products, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast and soy protein. Metagenics NeuroCalm Sleep is free from artificial colours, flavours and preservatives.

Free Froms: Metagenics NeuroCalm Sleep

Metagenics NeuroCalm Sleep is free from animal products, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast and soy protein. Metagenics NeuroCalm Sleep is free from artificial colours, flavours and preservatives.

Warnings: Metagenics NeuroCalm Sleep

Antidepressant medications: Zizyphus, California poppy and lavender may have additive effects, however beneficial interaction is likely under professional supervision. Monitor, and do not exceed recommended dosage.

Barbiturates: Magnolia and passionflower might increase the risk of drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle, or if involved in activities requiring mental alertness.

Benzodiazepines and CNS depressants: California poppy and zizyphus may have additive sedative effects. Exercise caution if operating heavy machinery, driving a motor vehicle, or if involved in activities requiring mental alertness. Monitor, and do not exceed recommended dose.

Diarrhoea: Zizyphus may exacerbate diarrhoea. Use with caution in people with severe diarrhoea.

Surgery: Due to CNS depressant effects and theoretical additive effects with anaesthesia or sedatives, it has been recommended that sedative herbs, such as California poppy, passionflower and lavender, should be discontinued at least 2 weeks before elective surgical procedures.

For full details, references or more information contact HealthMasters in Australia by email: reception@healthmasters.com.au

Contraindications: Metagenics NeuroCalm Sleep

Allergies and Sensitivities: Avoid in patients with known allergy/hypersensitivity to Zizyphus spp., its constituents, or members of the family Rhamnaceae (buckthorn) and Jamaican dogwood and/or members of the Fabaceae family.

Some components of some zizyphus species may cross react with latex IgE; those with severe latex allergy may react to zizyphus fruits.

Pregnancy and Lactation: Metagenics NeuroCalm Sleep

Pregnancy: Contraindicated in pregnancy. Lavender has been found to stimulate uterine contractions in an animal model. Zizyphus may also have uterine-stimulating activity. Avoid use during pregnancy.

Breastfeeding: Appropriate for use at recommended dosages.

Note: Metagenics CalmX is safe to use in pregnancy and breastfeeding and can be recommended as an alternative to NeuroCalm.

Storage: Metagenics NeuroCalm Sleep

Store below 30° C

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