Metagenics NasoClear 30 ml nasal spray

Directions

Adults:

2 sprays in each nostril, every two hours.

Direct the nozzle into your right nostril and spray twice, sniffing between each spray. Repeat in the left nostril or as directed by your healthcare professional.

Benefits

• Nasal irrigation has been shown in several clinical trials to relieve the symptoms of chronic rhinitis, sinusitis and colds.1,2,3 A controlled study of 150 adults with chronic sinusitis has shown daily nasal saline irrigation to improve symptoms in over 70% of subjects. There was also a significant decrease in the use of sinus medications in 35% of participants during the intervention.4 Potential efficacy of nasal irrigation is supported by the observation that a saline solution increases mucociliary clearance by moisturising the nasal cavity and removing encrusted material.5 Nasal irrigation may also reduce the viscosity of mucus and the concentration of inflammatory mediators found in mucus.6
• Saline solution with essential oils: Nasoclear contains a saline solution scented with essential oils from eucalyptus, thyme, lavender and peppermint for targeted nasal delivery in an easy to use nasal spray.

Ingredients

Metagenics NasoClear is free from animal products, corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, soy protein, starches and salt. Metagenics NasoClear is free from artificial colours and flavours.

Warnings

Not to be used in children under 2 years of age without medical advice. Contains sodium benzoate and potassium sorbate.

Not all cautions and contraindications are listed. For full details, references or more information contact HealthMasters in Australia by email: reception@healthmasters.com.au.

Always read the label. Use only as directed. If symptoms persist consult your healthcare professional.

Storage

Store below 30° C

Technical Information

NasoClear Antimicrobial Sinus Spray

NasoClear Antimicrobial Sinus Spray is designed to provide relief from the symptoms of sinusitis and rhinitis. Targeted for nasal delivery, saline, with the addition of xylitol and the decongesting, anti-inflammatory and antimicrobial essential oils of eucalyptus, thyme, lavender and peppermint, may help to reduce the nasal and sinus congestion that accompanies upper respiratory tract infections or hayfever.

Herbs and Nutrients That May Assist

• Sodium chloride
• Xylitol
• Eucalyptus spp. leaf essential oil
• Mentha X piperita (Peppermint) leaf essential oil
• Lavandula angustifolia (Lavender) flowering top essential oil
• Thymus vulgaris (thyme) leaf/flowering top oil essential

Clinical Applications

Key Applications

• Rhinitis
• Rhinosinusitis
• Upper respiratory tract infections with rhinitis or sinusitis
• Hay fever

Background/Technical Information

The essential oil of Eucalyptus globulus and other eucalyptus species is used traditionally in aromatherapy, both internally and topically, for its antiseptic properties, for sinusitis and other respiratory tract conditions. Along with eucalyptus essential oil’s antiinfectious activity, its anticatarrhal, anti-inflammatory, astringent, mucolytic and expectorant properties also make it valuable for the relief of coughs and sinusitis and other respiratory tract infections. It is a good remedy for hay fever, as well as infectious causes of sinusitis and stuffy noses, such as the common cold, to help clear the respiratory passages.2 Its content of 1,8 cineole is responsible for the expectorant effect and reduces swelling of mucous membranes and loosens phlegm, making breathing easier.3

Similarly, Lavandula angustifolia (lavender) essential oil is also used by aromatherapists as an internal and external antiseptic, where it is used to give relief from sinusitis and influenza, as well as lower respiratory tract diseases.4 Anti-inflammatory benefits combine with antiviral, bactericidal and decongestant actions for assistance in upper respiratory tract infections, hay fever and sinusitis.5,6

Mentha X piperita (peppermint) leaf essential oil is also used in traditional aromatherapy as a general antiseptic.7 It has antiinflammatory, astringent, decongestant, mucolytic and expectorant properties, and is beneficial for the treatment of colds and ‘flus, hay fever, and sinus congestion.8,9

Thymus vulgaris leaf and flowering top essential oil is another pulmonary antiseptic, and is used in traditional aromatherapy for influenza and sinusitis.10 The essential oils of the alcohol chemotypes of thyme, such as the linalool chemotype, * are less aggressive than the phenol chemotypes: phenols tend to be more irritating to the skin and mucous membranes. It is anti-inflammatory,11 and has immunostimulant properties, with applications in hay fever, as well as infectious sinusitis.12

* A variety of Thymus vulgaris that has an essential oil particularly high in the terpenol linalool.

Intranasal saline may assist in the relief of the symptoms of sinusitis and rhinitis. In patients with upper airway inflammatory secretions, the removal of these secretions allows the achievement of clinical improvement. This is, in part, because secretions are an ideal growth medium for major pathogens, such as Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus pneumonia. Nasal irrigation with isotonic sodium chloride solution also seems to be able to reduce nasal and rhinosinusal dryness, facilitating the clearance of thick mucus and crusts in patients affected by rhinosinusitis.13

A Cochrane review of randomised, controlled clinical trials of adults and children with the symptoms of chronic rhinosinusitis concluded that there is evidence that topical nasal saline relieves symptoms, help as an adjunct to treatment and is well tolerated by the majority of patients. No recommendations could be made regarding specific solutions, dosage or delivery.14 For example, atomised isotonic saline was found to significantly improve nasal function, including mucociliary transport time in a randomised, placebo-controlled trial of 200 individuals with the common cold.13

Xylitol is a 5-carbon sugar that may enhance the innate antibacterial defence system when applied nasally. A double-blind, randomised, cross-over study involved the spraying of either a 5% xylitol solution or a 0.9% saline solution into the nasal cavity for 4 days in 21 healthy volunteers. Both solutions were found to be effective in reducing the numbers of coagulase-negative Staphylococcus determined by culture of nasal swabs.15

Cautions/Contraindications

Contraindications

• Allergy or sensitivity to any of the Lamiaceae family.
• Pregnancy (see below)

Cautions

• Nil

Pregnancy and Lactation

• Contraindicated in pregnancy: peppermint and thyme essential oils.16

References

1 Valnet J. The Practice of Aromatherapy (translated from the French). Tisserand RB, Ed. Saffron Walden, Essex; The CW Daniel Co Ltd, 1982:pp122-4.

2 Price S, Price L. Aromatherapy for Health Professionals. Edinburgh; Churchill Livingstone, 1995:p249.

3 Battaglia S. The Complete Guide to Aromatherapy. Virginia, QLD; The Perfect Potion, 1995:pp159-61. 309-10.

4 Valnet J. The Practice of Aromatherapy (translated from the French). Tisserand RB, Ed. Saffron Walden, Essex; The CW Daniel Co Ltd, 1982:pp144-8.

5 Price S, Price L. Aromatherapy for Health Professionals. Edinburgh; Churchill Livingstone, 1995:pp252-3.

6 Battaglia S. The Complete Guide to Aromatherapy. Virginia, QLD; The Perfect Potion, 1995:pp171-2, 309-10.

7 Valnet J. The Practice of Aromatherapy (translated from the French). Tisserand RB, Ed. Saffron Walden, Essex; The CW Daniel Co Ltd, 1982:pp172-4.

8 Battaglia S. The Complete Guide to Aromatherapy. Virginia, QLD; The Perfect Potion, 1995:pp189-90, 309-10.

9 Price S, Price L. Aromatherapy for Health Professionals. Edinburgh; Churchill Livingstone, 1995:pp255-6.

10 Valnet J. The Practice of Aromatherapy (translated from the French). Tisserand RB, Ed. Saffron Walden, Essex; The CW Daniel Co Ltd, 1982:pp194-7.

11 Price S, Price L. Aromatherapy for Health Professionals. Edinburgh; Churchill Livingstone, 1995:p269.

12 Battaglia S. The Complete Guide to Aromatherapy. Virginia, QLD; The Perfect Potion, 1995:pp205, 309-310.

13 Passàli D, Damiani V, Passàli FM, Passàli GC, Bellussi L. Atomized nasal douche vs nasal lavage in acute viral rhinitis. Arch Otolaryngol Head Neck Surg. 2005 Sep;131(9):788-90.

14 Harvey R, Hannan SA, Badia L, Scadding G. Nasal saline irrigations for the symptoms of chronic rhinosinusitis. Cochrane Database Syst Rev. 2007 Jul 18;(3):CD006394.

15 Zabner J, Seiler MP, Launspach JL, Karp PH, Kearney WR, Look DC, Smith JJ, Welsh MJ. The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11614-9.

16 Battaglia S. The Complete Guide to Aromatherapy. Virginia, QLD; The Perfect Potion, 1995:pp136-7.