Metagenics ADEK Essentials 60 capsules
Taking some fat soluble vitamins together can optimise their efficacy, for example, when vitamin A and D are taken together, the expression of the RAR, VDR and RXR receptors and osteocalcin gene transcription are optimised.3 This is likely because RXR is the main partner receptor for the vitamin A RAR and the vitamin D VDR receptors.3
Fat soluble vitamin intake can be compromised.1 For example, up to 73% of Australians have insufficient vitamin D levels 4 Vitamin D from food sources is less biologically active and in insignificant amounts in most foods.1
Vitamins A, D and K are essential for bone health.2 Vitamin A regulates the proliferation, differentiation and gene expression of chondrocytes, osteoblasts and osteoclasts which express the RXR receptor, shared by vitamin D.5, 3 Both of these vitamins stimulate gene transcription of osteocalcin which binds calcium to new bone.6, 7 Vitamin K helps in the transport of calcium. 8
A range of nutrient forms for improved efficacy. ADEK Essentials contains 2500 IU of vitamin A and the equivalent amount of betacarotene.9 ADEK Essentials also contains all eight isomers of vitamin E found in nature, including four tocopherols and four tocotrienols (alpha-, beta-, gamma- and delta-).10
|Each capsule contains:|
|Tocopherols concentrate – mixed (low-alpha type)||225mg|
|Tocotrienols complex – palm*||35mg|
|Equivalent Vitamin A||750μg RE|
|Phytomenadione (vitamin K)||1.0mg|
|Equivalent Vitamin D1||1000IU|
Free from corn, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, soy protein, starches and salt. Free from artificial colours, flavours and preservatives.
Take 1 capsule daily with food, or as directed by your healthcare professional.
Warning: When taken in excess of 3000 micrograms retinol equivalents, vitamin A can cause birth defects. If you are pregnant, or considering becoming pregnant, do not take vitamin A supplements without consulting your doctor or pharmacist.
*The tocotrienols complex in ADEK Essentials is from sustainably sourced palm oil.
The recommended daily amount of vitamin A from all sources is 700 micrograms retinol equivalents for women and 900 micrograms retinol equivalents for men.
Store below 30° C