Designs For Health Ubiq-Evail
Directions: Designs For Health Ubiq-Evail
Adults: Take 1 capsule per day, or as directed by your healthcare practitioner
Ingredients: Designs For Health Ubiq-Evail
|Active ingredients per soft capsule:|
|Ubiquinol (activated Coenzyme Q10)||150mg|
Excipients: Designs For Health Ubiq-Evail
Puriﬁed water, Gamma-tocopherol, Tocopherol, Modiﬁed food starch, Silicon dioxide, Gelatin, Glycerol, Annatto, Tocofersolan, Medium chain triglycerides, Lecithin (sunﬂower)
Allergen Information: Designs For Health Ubiq-Evail
No Added: Gluten, Dairy, Soy or nuts
Warnings: Designs For Health Ubiq-Evail
Do not take whilst in warfarin therapy without medical advice.
If symptoms persist consult your healthcare practitioner
Storage: Designs For Health Ubiq-Evail
Store below 25°C away from direct sunlight.
Education: Designs For Health Ubiq-Evail
Coenzyme Q10 is a lipophilic compound existing in all cell membranes and lipoproteins. It exists in both an oxidised form as ubiquinone and reduced and functional form ubiquinol.1,2 It functions in the Mitochondrial Electron Transport Chain (ETC) in the production of Adenosine Triphosphate (ATP) and also acts as a potent lipophilic antioxidant.
The presence of Ubiquinol in the cell is essential to its functioning. Requisite amounts are vital to ensure mitochondrial health and subsequently cellular energy production, ROS scavenging and cell signalling.
Ubiquinol is a potent antioxidant acting on the regeneration of vitamins C and E. It also holds electrons loosely and can therefore freely donate them to quench lipid peroxyl radicals and other reactive oxygen species (ROS). Ubiquinol also has the ability to improve the functioning of Super Oxide Dismutase (SOD). This broad antioxidant action affects both the induction and escalation of Reactive Oxygen Species (ROS). CoQ10 protects LDL’s, polyunsaturated fatty acids, proteins, DNA, endothelial tissues, cell membranes and mitochondrial function from free radical damage.'
Ubiquinol influences the expression of multiple NF-ΚB1 dependent genes4 which are upregulated in the presence of oxidative stress. Ubiquinol is uniquely able to quench both the ROS causing the initial oxidation (via mechanisms above), and the subsequent release of inflammatory cytokines such as TNF-α and IL-63 putting a wedge in the cyclic interplay between inflammation and tissue oxidation.
Ubiquinol Supports endothelial health and function and conserves mitochondrial bioenergetics supporting the contractile function of the heart. It can also prevent the oxidation of circulating lipoproteins and enable optimal vasoreactivity and blood vessel health.
Ubiquinol is a cofactor for electron transport in ATP production in the mitochondrial Electron Transport Chain. Higher amounts are found in cells with higher energy expenditure such as the heart, kidneys, and liver. During excessive activity such as exercise and cognitive tasks, cells and tissues can become damaged by reactive oxygen species, and fatigue ensues. Recovery from fatigue occurs while this damage is repaired by antioxidant mechanisms. Ubiquinol is vital to energy production and is involved in numerous antioxidant systems giving it a unique “anti-fatigue” effect.