{"id":8115076432102,"title":"Designs For Health Tri-Mag Restful Night","handle":"designs-for-health-tri-mag-restful-night","description":"\u003ch2\u003eDesigns For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eContains a customised blend of 3 sources of magnesium, plus affron – a clinically studied Saffron extract to promote a deep and refreshing sleep and support muscle relaxation\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003eSize: 210g   Flavours: Dreamy Chocolate or Delicious Lemon Lemonade\u003c\/p\u003e\n\u003cp\u003eDesigns For Health Tri-Mag Restful Night Summary:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eA nutritional and herbal formulation with sedative properties to promote sleep\u003c\/li\u003e\n\u003cli\u003eProvides 300 mg of magnesium per serve\u003c\/li\u003e\n\u003cli\u003eContains a unique and specific blend of three Magnesium salts for optimal sleep support\u003c\/li\u003e\n\u003cli\u003eEach 7g serve contains 3.9gm of glycine\u003c\/li\u003e\n\u003cli\u003eUtilises affron, a standardised extract of Saffron, clinically studied in subjects reporting poor sleep\u003c\/li\u003e\n\u003cli\u003eIncludes Passionflower and California poppy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003eNo added: Gluten, dairy, soy, or nuts\u003c\/p\u003e\n\u003cp\u003eVegan Friendly\u003c\/p\u003e\n\u003cp\u003eDesigns For Health Tri-Mag Restful Night Chocolate AUST L 392710\u003c\/p\u003e\n\u003cp\u003eDesigns For Health Tri-Mag Restful Night Lemon Lemonade AUST L 393441\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDirections\u003c\/h5\u003e\n\u003ch2\u003eDirections: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eAdults:\u003c\/strong\u003e mix 7 g (one level scoop) of the chocolate-flavoured powder into 200 ml of water or your preferred milk and consume immediately. Take 1 hour before bed, or as directed by your healthcare practitioner\u003c\/p\u003e\n\u003ch5\u003eBenefits\u003c\/h5\u003e\n\u003ch2\u003eBenefits: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eImprovements to sleep quality\u003c\/li\u003e\n\u003cli\u003eA more refreshing sleep\u003c\/li\u003e\n\u003cli\u003eSteady maintenance of emotional wellbeing and mood balance\u003c\/li\u003e\n\u003cli\u003eNutritional support for a healthy nervous system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eActive ingredients (per 7g dose)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium glycinate\u003c\/td\u003e\n\u003ctd\u003e1.1g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Magnesium\u003c\/td\u003e\n\u003ctd\u003e150mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eContains Glycine\u003c\/td\u003e\n\u003ctd\u003e920mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium glycerophosphate\u003c\/td\u003e\n\u003ctd\u003e909.4mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Magnesium\u003c\/td\u003e\n\u003ctd\u003e100mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium citrate\u003c\/td\u003e\n\u003ctd\u003e309.3mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Magnesium\u003c\/td\u003e\n\u003ctd\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal Magnesium\u003c\/td\u003e\n\u003ctd\u003e300mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlycine\u003c\/td\u003e\n\u003ctd\u003e3g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal Glycine\u003c\/td\u003e\n\u003ctd\u003e3.92g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCrocus sativus (affron) ext. dry conc.\u003c\/td\u003e\n\u003ctd\u003e28mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFrom min dry stigma\u003c\/td\u003e\n\u003ctd\u003e84mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEschscholzia californica ext. dry conc.\u003c\/td\u003e\n\u003ctd\u003e100mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. dry herb top\/flower\u003c\/td\u003e\n\u003ctd\u003e1.5g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePassiflora incarnata ext. dry conc.\u003c\/td\u003e\n\u003ctd\u003e30mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. dry flower\u003c\/td\u003e\n\u003ctd\u003e3g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003cp\u003eAcacia\u003c\/p\u003e\n\u003cp\u003eCitric acid\u003c\/p\u003e\n\u003cp\u003eColloidal anhydrous silica\u003c\/p\u003e\n\u003cp\u003eNatural vanilla and chocolate powder\u003c\/p\u003e\n\u003cp\u003eNatural lemon powder\u003c\/p\u003e\n\u003cp\u003eLemon lemonade powder\u003c\/p\u003e\n\u003cp\u003eMaltodextrin\u003c\/p\u003e\n\u003cp\u003eStevia rebaudiana\u003c\/p\u003e\n\u003ch5\u003eAllergen Information\u003c\/h5\u003e\n\u003ch2\u003eAllergen Information: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003cp\u003eNo added: Gluten, dairy, lactose, soy, or nuts\u003c\/p\u003e\n\u003cp\u003eVegan Friendly\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003cp\u003eIf symptoms persist, seek the advice of a healthcare professional\u003c\/p\u003e\n\u003cp\u003eVitamin and\/or mineral supplements should not replace a balanced diet.\u003c\/p\u003e\n\u003cp\u003eNot to be used during pregnancy and\/or breastfeeding.\u003c\/p\u003e\n\u003cp\u003eContains sulfites and phenylalanine\u003c\/p\u003e\n\u003ch5\u003eEducation\u003c\/h5\u003e\n\u003ch2\u003eEducation: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003ch3\u003eMagnesium\u003c\/h3\u003e\n\u003cp\u003eMagnesium is one of the most ubiquitous and essential minerals in the body. It is a critical nutrient in almost every cellular metabolic and biological process, with enzyme databases listing over 600 enzymes that use magnesium as a co-factor and a further 200 being directly activated by magnesium. As a natural calcium channel blocker, muscle relaxant, facilitator of calming effects upon the nervous system, and a required element for electrolyte balance and proper functioning of sodium-potassium ATPase pumps, magnesium plays a crucial role in supporting, muscle contraction and relaxation, neurological health, neurotransmission and psychological balance.\u003c\/p\u003e\n\u003ch3\u003eSkeletal muscle \u0026amp; nervous system function\u003c\/h3\u003e\n\u003cp\u003eMagnesium is a critical regulator of the activity rate of the Sodium-Potassium ATPase pump (Na+, K+- ATPase pump), which is required for the removal of sodium from inside the cell in exchange for potassium. This makes Magnesium vital for maintaining the electrical potential of skeletal muscles and nerves and for neurotransmission across neuromuscular junctions.   As well as moderating the function and activity of the Na+, K+- ATPase pump, subsequently affecting both contraction and relaxation phases of muscle movement, magnesium also contributes to skeletal muscle function by facilitating oxygen utilisation, ATP production and electrolyte balance.   In the nervous system, Magnesium is vital for neurotransmitter binding and subsequent transmission. Magnesium can cross the blood-brain barrier and acts as a calcium antagonist at neuromuscular junctions, affecting NMDA receptors. It also agonises GABA receptors, thereby having an overall calming effect on the nervous system.   Magnesium absorption is seen as a challenge as various factors such as solubility, gastric pH, the formation of a hydration shell, and transport can influence magnesium bioavailability. Organic forms such as citrates, amino acid chelates, glycinates, aspartates and glycerophosphates tend to have the most optimal bioavailability profiles.\u003c\/p\u003e\n\u003ch3\u003eSaffron\u003c\/h3\u003e\n\u003cp\u003eSaffron is a herb that has been used for thousands of years for its effects on inflammation and the nervous system. Saffron contains three main constituents that show the most biological activity, and they are known collectively as “lepticrosalides”. They include crocin, picrocrocin and safranal. Modern investigations have confirmed Saffron’s traditional uses, particularly its effects on mood and sleep. The ability of Saffron to improve sleep quality is thought to be brought about by mechanisms relating to its possible influence over melatonin production, improvements in delta powdered sleep phases and non-rapid eye movement sleep Moreover, the general calming effects that Saffron brings to the nervous system may also contribute to its ability to promote a more refreshing sleep Driving Saffron’s effects on emotional well-being and mood balance are its serotonergic, anti-inflammatory, antioxidant, neuro-endocrine (dampens HPA response to stress), neuroprotective and soporific activity. Saffron’s constituents can interact with the cholinergic, glutamatergic and GABA systems whilst increasing cAMP response element binding protein (CREB) and brain-derived neurotropic factor (BDNF) providing neuroprotective effects.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2023-01-19T14:29:50+11:00","created_at":"2023-01-19T13:12:36+11:00","vendor":"Designs For Health","type":"Designs For Health Naturopathic Medicines","tags":["Designs For Health","Naturopathic","PB"],"price":5216,"price_min":5216,"price_max":5216,"available":true,"price_varies":false,"compare_at_price":5795,"compare_at_price_min":5795,"compare_at_price_max":5795,"compare_at_price_varies":false,"variants":[{"id":43621264523494,"title":"Chocolate 210g","option1":"Chocolate 210g","option2":null,"option3":null,"sku":"DFHTri-MagRfulNightChoc210g","requires_shipping":true,"taxable":true,"featured_image":{"id":39099959902438,"product_id":8115076432102,"position":3,"created_at":"2023-01-19T13:51:17+11:00","updated_at":"2023-01-19T13:54:08+11:00","alt":"Designs For Health Tri-Mag Restful Night Chocolate 210g 10% off RRP at HealthMasters Designs For Healt","width":1200,"height":1200,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/DesignsForHealthTri-MagRestfulNightChocolate210g10_offRRPatHealthMastersDesignsForHealt.png?v=1674096848","variant_ids":[43621264523494]},"available":true,"name":"Designs For Health Tri-Mag Restful Night - 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Take 1 hour before bed, or as directed by your healthcare practitioner\u003c\/p\u003e\n\u003ch5\u003eBenefits\u003c\/h5\u003e\n\u003ch2\u003eBenefits: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eImprovements to sleep quality\u003c\/li\u003e\n\u003cli\u003eA more refreshing sleep\u003c\/li\u003e\n\u003cli\u003eSteady maintenance of emotional wellbeing and mood balance\u003c\/li\u003e\n\u003cli\u003eNutritional support for a healthy nervous system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eActive ingredients (per 7g dose)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium glycinate\u003c\/td\u003e\n\u003ctd\u003e1.1g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Magnesium\u003c\/td\u003e\n\u003ctd\u003e150mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eContains Glycine\u003c\/td\u003e\n\u003ctd\u003e920mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium glycerophosphate\u003c\/td\u003e\n\u003ctd\u003e909.4mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Magnesium\u003c\/td\u003e\n\u003ctd\u003e100mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium citrate\u003c\/td\u003e\n\u003ctd\u003e309.3mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. Magnesium\u003c\/td\u003e\n\u003ctd\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal Magnesium\u003c\/td\u003e\n\u003ctd\u003e300mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlycine\u003c\/td\u003e\n\u003ctd\u003e3g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal Glycine\u003c\/td\u003e\n\u003ctd\u003e3.92g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCrocus sativus (affron) ext. dry conc.\u003c\/td\u003e\n\u003ctd\u003e28mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFrom min dry stigma\u003c\/td\u003e\n\u003ctd\u003e84mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEschscholzia californica ext. dry conc.\u003c\/td\u003e\n\u003ctd\u003e100mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. dry herb top\/flower\u003c\/td\u003e\n\u003ctd\u003e1.5g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePassiflora incarnata ext. dry conc.\u003c\/td\u003e\n\u003ctd\u003e30mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eequiv. dry flower\u003c\/td\u003e\n\u003ctd\u003e3g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eExcipients\u003c\/h5\u003e\n\u003ch2\u003eExcipients: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003cp\u003eAcacia\u003c\/p\u003e\n\u003cp\u003eCitric acid\u003c\/p\u003e\n\u003cp\u003eColloidal anhydrous silica\u003c\/p\u003e\n\u003cp\u003eNatural vanilla and chocolate powder\u003c\/p\u003e\n\u003cp\u003eNatural lemon powder\u003c\/p\u003e\n\u003cp\u003eLemon lemonade powder\u003c\/p\u003e\n\u003cp\u003eMaltodextrin\u003c\/p\u003e\n\u003cp\u003eStevia rebaudiana\u003c\/p\u003e\n\u003ch5\u003eAllergen Information\u003c\/h5\u003e\n\u003ch2\u003eAllergen Information: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003cp\u003eNo added: Gluten, dairy, lactose, soy, or nuts\u003c\/p\u003e\n\u003cp\u003eVegan Friendly\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003cp\u003eIf symptoms persist, seek the advice of a healthcare professional\u003c\/p\u003e\n\u003cp\u003eVitamin and\/or mineral supplements should not replace a balanced diet.\u003c\/p\u003e\n\u003cp\u003eNot to be used during pregnancy and\/or breastfeeding.\u003c\/p\u003e\n\u003cp\u003eContains sulfites and phenylalanine\u003c\/p\u003e\n\u003ch5\u003eEducation\u003c\/h5\u003e\n\u003ch2\u003eEducation: Designs For Health Tri-Mag Restful Night\u003c\/h2\u003e\n\u003ch3\u003eMagnesium\u003c\/h3\u003e\n\u003cp\u003eMagnesium is one of the most ubiquitous and essential minerals in the body. It is a critical nutrient in almost every cellular metabolic and biological process, with enzyme databases listing over 600 enzymes that use magnesium as a co-factor and a further 200 being directly activated by magnesium. As a natural calcium channel blocker, muscle relaxant, facilitator of calming effects upon the nervous system, and a required element for electrolyte balance and proper functioning of sodium-potassium ATPase pumps, magnesium plays a crucial role in supporting, muscle contraction and relaxation, neurological health, neurotransmission and psychological balance.\u003c\/p\u003e\n\u003ch3\u003eSkeletal muscle \u0026amp; nervous system function\u003c\/h3\u003e\n\u003cp\u003eMagnesium is a critical regulator of the activity rate of the Sodium-Potassium ATPase pump (Na+, K+- ATPase pump), which is required for the removal of sodium from inside the cell in exchange for potassium. This makes Magnesium vital for maintaining the electrical potential of skeletal muscles and nerves and for neurotransmission across neuromuscular junctions.   As well as moderating the function and activity of the Na+, K+- ATPase pump, subsequently affecting both contraction and relaxation phases of muscle movement, magnesium also contributes to skeletal muscle function by facilitating oxygen utilisation, ATP production and electrolyte balance.   In the nervous system, Magnesium is vital for neurotransmitter binding and subsequent transmission. Magnesium can cross the blood-brain barrier and acts as a calcium antagonist at neuromuscular junctions, affecting NMDA receptors. It also agonises GABA receptors, thereby having an overall calming effect on the nervous system.   Magnesium absorption is seen as a challenge as various factors such as solubility, gastric pH, the formation of a hydration shell, and transport can influence magnesium bioavailability. Organic forms such as citrates, amino acid chelates, glycinates, aspartates and glycerophosphates tend to have the most optimal bioavailability profiles.\u003c\/p\u003e\n\u003ch3\u003eSaffron\u003c\/h3\u003e\n\u003cp\u003eSaffron is a herb that has been used for thousands of years for its effects on inflammation and the nervous system. Saffron contains three main constituents that show the most biological activity, and they are known collectively as “lepticrosalides”. They include crocin, picrocrocin and safranal. Modern investigations have confirmed Saffron’s traditional uses, particularly its effects on mood and sleep. The ability of Saffron to improve sleep quality is thought to be brought about by mechanisms relating to its possible influence over melatonin production, improvements in delta powdered sleep phases and non-rapid eye movement sleep Moreover, the general calming effects that Saffron brings to the nervous system may also contribute to its ability to promote a more refreshing sleep Driving Saffron’s effects on emotional well-being and mood balance are its serotonergic, anti-inflammatory, antioxidant, neuro-endocrine (dampens HPA response to stress), neuroprotective and soporific activity. Saffron’s constituents can interact with the cholinergic, glutamatergic and GABA systems whilst increasing cAMP response element binding protein (CREB) and brain-derived neurotropic factor (BDNF) providing neuroprotective effects.\u003c\/p\u003e\n\u003c!-- \/TABS --\u003e"}

Designs For Health Tri-Mag Restful Night

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Product Details

Designs For Health Tri-Mag Restful Night

Contains a customised blend of 3 sources of magnesium, plus affron – a clinically studied Saffron extract to promote a deep and refreshing sleep and support muscle relaxation

Size: 210g   Flavours: Dreamy Chocolate or Delicious Lemon Lemonade

Designs For Health Tri-Mag Restful Night Summary:

  • A nutritional and herbal formulation with sedative properties to promote sleep
  • Provides 300 mg of magnesium per serve
  • Contains a unique and specific blend of three Magnesium salts for optimal sleep support
  • Each 7g serve contains 3.9gm of glycine
  • Utilises affron, a standardised extract of Saffron, clinically studied in subjects reporting poor sleep
  • Includes Passionflower and California poppy

    No added: Gluten, dairy, soy, or nuts

    Vegan Friendly

    Designs For Health Tri-Mag Restful Night Chocolate AUST L 392710

    Designs For Health Tri-Mag Restful Night Lemon Lemonade AUST L 393441

    Directions: Designs For Health Tri-Mag Restful Night

    Adults: mix 7 g (one level scoop) of the chocolate-flavoured powder into 200 ml of water or your preferred milk and consume immediately. Take 1 hour before bed, or as directed by your healthcare practitioner

    Benefits: Designs For Health Tri-Mag Restful Night

    • Improvements to sleep quality
    • A more refreshing sleep
    • Steady maintenance of emotional wellbeing and mood balance
    • Nutritional support for a healthy nervous system

    Ingredients: Designs For Health Tri-Mag Restful Night

    Active ingredients (per 7g dose)
    Magnesium glycinate 1.1g
    equiv. Magnesium 150mg
    Contains Glycine 920mg
    Magnesium glycerophosphate 909.4mg
    equiv. Magnesium 100mg
    Magnesium citrate 309.3mg
    equiv. Magnesium 50mg
    Total Magnesium 300mg
    Glycine 3g
    Total Glycine 3.92g
    Crocus sativus (affron) ext. dry conc. 28mg
    From min dry stigma 84mg
    Eschscholzia californica ext. dry conc. 100mg
    equiv. dry herb top/flower 1.5g
    Passiflora incarnata ext. dry conc. 30mg
    equiv. dry flower 3g

    Excipients: Designs For Health Tri-Mag Restful Night

    Acacia

    Citric acid

    Colloidal anhydrous silica

    Natural vanilla and chocolate powder

    Natural lemon powder

    Lemon lemonade powder

    Maltodextrin

    Stevia rebaudiana

    Allergen Information: Designs For Health Tri-Mag Restful Night

    No added: Gluten, dairy, lactose, soy, or nuts

    Vegan Friendly

    Warnings: Designs For Health Tri-Mag Restful Night

    If symptoms persist, seek the advice of a healthcare professional

    Vitamin and/or mineral supplements should not replace a balanced diet.

    Not to be used during pregnancy and/or breastfeeding.

    Contains sulfites and phenylalanine

    Education: Designs For Health Tri-Mag Restful Night

    Magnesium

    Magnesium is one of the most ubiquitous and essential minerals in the body. It is a critical nutrient in almost every cellular metabolic and biological process, with enzyme databases listing over 600 enzymes that use magnesium as a co-factor and a further 200 being directly activated by magnesium. As a natural calcium channel blocker, muscle relaxant, facilitator of calming effects upon the nervous system, and a required element for electrolyte balance and proper functioning of sodium-potassium ATPase pumps, magnesium plays a crucial role in supporting, muscle contraction and relaxation, neurological health, neurotransmission and psychological balance.

    Skeletal muscle & nervous system function

    Magnesium is a critical regulator of the activity rate of the Sodium-Potassium ATPase pump (Na+, K+- ATPase pump), which is required for the removal of sodium from inside the cell in exchange for potassium. This makes Magnesium vital for maintaining the electrical potential of skeletal muscles and nerves and for neurotransmission across neuromuscular junctions.   As well as moderating the function and activity of the Na+, K+- ATPase pump, subsequently affecting both contraction and relaxation phases of muscle movement, magnesium also contributes to skeletal muscle function by facilitating oxygen utilisation, ATP production and electrolyte balance.   In the nervous system, Magnesium is vital for neurotransmitter binding and subsequent transmission. Magnesium can cross the blood-brain barrier and acts as a calcium antagonist at neuromuscular junctions, affecting NMDA receptors. It also agonises GABA receptors, thereby having an overall calming effect on the nervous system.   Magnesium absorption is seen as a challenge as various factors such as solubility, gastric pH, the formation of a hydration shell, and transport can influence magnesium bioavailability. Organic forms such as citrates, amino acid chelates, glycinates, aspartates and glycerophosphates tend to have the most optimal bioavailability profiles.

    Saffron

    Saffron is a herb that has been used for thousands of years for its effects on inflammation and the nervous system. Saffron contains three main constituents that show the most biological activity, and they are known collectively as “lepticrosalides”. They include crocin, picrocrocin and safranal. Modern investigations have confirmed Saffron’s traditional uses, particularly its effects on mood and sleep. The ability of Saffron to improve sleep quality is thought to be brought about by mechanisms relating to its possible influence over melatonin production, improvements in delta powdered sleep phases and non-rapid eye movement sleep Moreover, the general calming effects that Saffron brings to the nervous system may also contribute to its ability to promote a more refreshing sleep Driving Saffron’s effects on emotional well-being and mood balance are its serotonergic, anti-inflammatory, antioxidant, neuro-endocrine (dampens HPA response to stress), neuroprotective and soporific activity. Saffron’s constituents can interact with the cholinergic, glutamatergic and GABA systems whilst increasing cAMP response element binding protein (CREB) and brain-derived neurotropic factor (BDNF) providing neuroprotective effects.

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