{"id":4842122510395,"title":"BioCeuticals Clinical NuroBalance Forte 60tabs","handle":"bioceuticals-clinical-nurobalance-forte","description":"\u003ch2\u003eBioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eSupports Healthy Mood Balance\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eServing Type:\u003c\/strong\u003e Tablet\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAvailable in Sizes\u003c\/strong\u003e: 60 tablets\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte is part of the BioCeuticals Clinical Range\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte combines the latest in clinical research to provide patients with an effective mood support formula. Developed following emerging evidence in the areas of complementary medicine and mood, NuroBalance Forte features traditional and well-researched herbal ingredients.\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte is associated with Cognitive Health and Nervous System\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte has No Added Dairy, No Added Gluten, No Added Shellfish, No Added Soy Protein, Vegan Friendly, Vegetarian Friendly, No Added Yeast.\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte AUST L 307546\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe naturopathic medicines listed below are suggestions that may be used as a substitute if the naturopathic medicines you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-clinical-saffropea\" target=\"_blank\" title=\"BioCeuticals Clinical SaffroPEA 10% off RRP | HealthMasters BioCeuticals Clinical\" rel=\"noopener\"\u003eBioCeuticals Clinical SaffroPEA\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca rel=\"noopener noreferrer\" title=\"Similar Products Containing Saffron | HealthMasters Saffron\" href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/saffron\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/saffron\" target=\"_blank\"\u003eSimilar Products Containing Saffron\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate naturopathic medicines, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca title=\"Contact HealthMasters For Assistance\" href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cstrong\u003eAdults:\u003c\/strong\u003e Take 1 tablet twice daily or as directed by your healthcare practitioner.\n\u003ch5\u003eFeatures \u0026amp; Benefits\u003c\/h5\u003e\n\u003ch2\u003eFeatures \u0026amp; Benefits: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCombination of saffron and St John’s wort, used in Persian traditional medicine and traditional western herbal medicine, respectively, to support a healthy mood balance, with mimosa, Siberian ginseng, zinc and myo-inositol.\u003c\/li\u003e\n\u003cli\u003eContains affron®, a clinically trialled saffron extract shown to support healthy mood balance. affron® is standardised to contain at least 3.5% Lepticrosalides®, a measure of phyto compounds including the bioactive compounds safranal and crocin.\u003c\/li\u003e\n\u003cli\u003eContains St John’s wort extract standardised to hypericin and \u0026lt;1% hyperforin.\u003c\/li\u003e\n\u003cli\u003eContains Siberian ginseng, used in traditional western herbal medicine as an adaptogen and to relieve fatigue, standardised to syringaresinol diglucosides.\u003c\/li\u003e\n\u003cli\u003eWith the addition of: an extract equivalent to 1.5g of mimosa; zinc, to support cognitive function; and myo-inositol, which supports the signal transduction between nerve cells.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCrocus sativus (saffron)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSaffron has been used in Persian traditional medicine for supporting healthy mood balance1 and has emerged as a leading herb in healthy moods. affron® is a clinically trialled, non-GMO saffron extract standardised to \u0026gt;3.5% Lepticrosalides®, a measure of the bioactive compunds found in saffron, including safranal and crocin. In clinical trials, affron® administered at 28mg\/day was shown to improve healthy mood balance and decreased somatisation, and was reportedly well tolerated.2,3 Saffron exerts its actions through inhibition of the reuptake of the monoamines (dopamine, serotonin and noradrenaline), and enhanced binding and sensitisation of serotonin receptors.1,4-6\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHypericum perforatum (St John’s wort)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSt John’s wort has a long history of use in traditional western herbal medicine for symptoms of mild anxiety and to support a healthy mood balance. In vivo and in vitro clinical studies have conirmed numerous effects in the body including inhibited synaptic reuptake of monoamines (dopamine, serotonin and noradrenaline), enhanced binding and sensitisation of monoamine oxidase inhibition and gamma-aminobutyric acid (GABA) receptor binding.4,7\u003c\/p\u003e\n\u003cp\u003eThe St John’s wort extract used in NuroBalance Forte contains various lavonoids, including hypericin and less than 1% of hyperforin. Hyperforin is the constituent that is attributed to enzyme modulation and subsequent medicinal disruption.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEleutherococcus senticosus (Siberian ginseng)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSiberian ginseng has traditionally been used in western herbal medicine as an adaptogen, and to relieve fatigue.8 In an animal study, the ginsenosides found in Siberian ginseng upregulated brain-derived neurotrophic factor (BDNF) signalling pathways and acted on GABA receptors.9\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional support\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMimosa, zinc and myo-inositol complete the formulation of NuroBalance Forte.\u003c\/p\u003e\n\u003cp\u003eMimosa has a history of use in traditional Chinese medicine.10\u003c\/p\u003e\n\u003cp\u003eZinc is an essential trace mineral that supports nervous system function, and cognitive and mental function.7 The highest levels of zinc are found in the brain, with altered levels linked to changes in behaviour, mood, learning and mental function.11,12\u003c\/p\u003e\n\u003cp\u003eMyo-inositol is the bioactive form of inositol and is essential for signal transduction between nerve cells; it is a constituent of the intracellular phophatidyl inositol secondary messenger system, which is linked to several neurotransmitters including alpha-1-noradrenergic, serotonin, dopamine, norepinephrine, glutamate and cholinergic receptors.13\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003ctable width='100%\"'\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach tablet contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHerbal extracts standardised equiv. to dry:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHypericum perforatum (St John's wort)\u003c\/td\u003e\n\u003ctd\u003e2.7g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 30px;\" data-mce-style=\"padding-left: 30px;\"\u003eequiv. to hyperforin\u003c\/td\u003e\n\u003ctd\u003e13.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 30px;\" data-mce-style=\"padding-left: 30px;\"\u003eequiv. to hypericins calc. as hypericin\u003c\/td\u003e\n\u003ctd\u003e1.49mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEleutherococcus senticosus (Siberian ginseng)\u003c\/td\u003e\n\u003ctd\u003e2g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 30px;\" data-mce-style=\"padding-left: 30px;\"\u003eequiv. to syringaresinol diglucosides\u003c\/td\u003e\n\u003ctd\u003e1.06mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHerbal extract equiv. to dry:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAlbizia julibrissin (mimosa) stem bark outer\u003c\/td\u003e\n\u003ctd\u003e1.5g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCrocus sativus (saffron) stigma (affron®)\u003c\/td\u003e\n\u003ctd\u003e42mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eNutrients:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZinc amino acid chelate\u003c\/td\u003e\n\u003ctd\u003e62.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 30px;\" data-mce-style=\"padding-left: 30px;\"\u003eequiv. to zinc\u003c\/td\u003e\n\u003ctd\u003e12.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInositol (myo-inositol)\u003c\/td\u003e\n\u003ctd\u003e300mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eFree Froms\u003c\/h5\u003e\n\u003ch2\u003eFree Froms: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eBioCeuticals Clinical NuroBalance Forte \u003c\/span\u003e\u003cspan\u003ehas No Added Dairy, No Added Gluten, No Added Shellfish, No Added Soy Protein, Vegan Friendly, Vegetarian Friendly, No Added Yeast.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cp\u003eSt John’s wort affects the way many prescription medicines work – including the oral contraceptive pill; consult your doctor.\u003c\/p\u003e\n\u003ch5\u003eCompanion Products:\u003c\/h5\u003e\n\u003ch2\u003eCompanion Products: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eBasti AA, Moshiri E, Noorbala AA, et al. Comparison of petal of Crocus sativus L. and luoxetine in the treatment of depressed outpatients: a pilot double-blind randomized trial. Prog Neuro-Psychopharmacol Biol Psychiatry 2007;31:439-442.\u003c\/li\u003e\n\u003cli\u003eKell G, Rao A, Beccaria G, et al. Affron®, a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial. Complement Ther Med 2017;33:58-64. 3. Lopresti AL, Drummond PD, Inarejos-García AM, et al. Affron®, a standardised extract from saffron (Crocus sativus L.) for the treatment of youth anxiety and depressive symptoms: a randomised, double-blind, placebo- scontrolled study. J Affect Disord 2018;232:349-357.\u003c\/li\u003e\n\u003cli\u003eSarris J, Panossian A, Schweitzer I, et al. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence. Eur Neuropsychopharm 2011;21(12):841-860.\u003c\/li\u003e\n\u003cli\u003eAkhondzadeh S, Tahmacebi-Pour N, Noorbala AA, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo- controlled trial. Phytother Res 2005;19(2):148-151.\u003c\/li\u003e\n\u003cli\u003eAkhondzadeh S, Fallah-Pour H, Afkham K, et al. Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double- blind randomized trial. BMC Complement Altern Med 2004;4(12).\u003c\/li\u003e\n\u003cli\u003eBraun L, Cohen M. Herbs and natural supplements: an evidence-based guide, 3rd ed. Sydney: Churchill Livingstone Elsevier, 2010.\u003c\/li\u003e\n\u003cli\u003eAmerican Botanical Council. Eleuthero root. Herbal medicine: expanded commission E, 1994. Viewed 30th July 2018, http:\/\/cms.herbalgram.org\/expandedE\/ Eleutheroroot.html?ts=1532925160\u0026amp;signature=dee3ecc afba172e 4930dcec9c4ef7f4c\u003c\/li\u003e\n\u003cli\u003eKim HJ, Kim P, Shin CY. A comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system. J Ginseng Res 2013;37(1):8-29.\u003c\/li\u003e\n\u003cli\u003eBensky D, Clavey S, Stoger E. Chinese herbal medicine materia medica, 3rd ed. Seattle: Eastland Press, 2004.\u003c\/li\u003e\n\u003cli\u003eNowak G, Szewczyk B, Pilc A. Zinc and depression. An update. Pharmacol Rep 2005;57(6):713-718.\u003c\/li\u003e\n\u003cli\u003eLai J, Moxey A, Nowak G, et al. The eficacy of zinc supplementation in depression: systematic review of randomised controlled trials. J Affect Disord 2012;136 (1 2):e31-39.\u003c\/li\u003e\n\u003cli\u003eInositol. Natural Medicines Database, 2018. Viewed 30th July 2018, https:\/\/naturalmedicines.therapeuticresearch com\/databases\/food,-herbs-supplements\/professional aspx?productid=299\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c!-- \/TABS --\u003e","published_at":"2022-10-11T14:05:49+11:00","created_at":"2020-04-26T08:08:23+10:00","vendor":"BioCeuticals","type":"BioCeuticals Clinical Naturopathic Medicines","tags":["BioCeuticals Clinical","Inositol","Naturopathic","PB","Saffron","SOOS"],"price":4316,"price_min":4316,"price_max":4316,"available":false,"price_varies":false,"compare_at_price":4795,"compare_at_price_min":4795,"compare_at_price_max":4795,"compare_at_price_varies":false,"variants":[{"id":33507478306875,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"BiCClNuroBalanceForte60T","requires_shipping":true,"taxable":true,"featured_image":null,"available":false,"name":"BioCeuticals Clinical NuroBalance Forte 60tabs","public_title":null,"options":["Default Title"],"price":4316,"weight":284,"compare_at_price":4795,"inventory_quantity":0,"inventory_management":"shopify","inventory_policy":"deny","barcode":"9337896002827","requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsClinicalNuroBalanceForte10_offRRPatHealthMasters.jpg?v=1609729811","\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsClinicalNuroBalanceFortepill10_offRRPatHealthMasters.jpg?v=1609729811"],"featured_image":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsClinicalNuroBalanceForte10_offRRPatHealthMasters.jpg?v=1609729811","options":["Title"],"media":[{"alt":"BioCeuticals Clinical NuroBalance Forte 10% off RRP at HealthMasters BioCeuticals Clinical","id":7986432704571,"position":1,"preview_image":{"aspect_ratio":0.76,"height":500,"width":380,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsClinicalNuroBalanceForte10_offRRPatHealthMasters.jpg?v=1609729811"},"aspect_ratio":0.76,"height":500,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsClinicalNuroBalanceForte10_offRRPatHealthMasters.jpg?v=1609729811","width":380},{"alt":"BioCeuticals Clinical NuroBalance Forte pill 10% off RRP at HealthMasters BioCeuticals Clinical","id":7986432737339,"position":2,"preview_image":{"aspect_ratio":1.75,"height":96,"width":168,"src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsClinicalNuroBalanceFortepill10_offRRPatHealthMasters.jpg?v=1609729811"},"aspect_ratio":1.75,"height":96,"media_type":"image","src":"\/\/shop.healthmasters.com.au\/cdn\/shop\/products\/BioCeuticalsClinicalNuroBalanceFortepill10_offRRPatHealthMasters.jpg?v=1609729811","width":168}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch2\u003eBioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003ch3\u003e\u003cem\u003eSupports Healthy Mood Balance\u003c\/em\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eServing Type:\u003c\/strong\u003e Tablet\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAvailable in Sizes\u003c\/strong\u003e: 60 tablets\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte is part of the BioCeuticals Clinical Range\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte combines the latest in clinical research to provide patients with an effective mood support formula. Developed following emerging evidence in the areas of complementary medicine and mood, NuroBalance Forte features traditional and well-researched herbal ingredients.\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte is associated with Cognitive Health and Nervous System\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte has No Added Dairy, No Added Gluten, No Added Shellfish, No Added Soy Protein, Vegan Friendly, Vegetarian Friendly, No Added Yeast.\u003c\/p\u003e\n\u003cp\u003eBioCeuticals Clinical NuroBalance Forte AUST L 307546\u003c\/p\u003e\n\u003ch4\u003eSimilar Products\u003c\/h4\u003e\n\u003cp\u003eThe naturopathic medicines listed below are suggestions that may be used as a substitute if the naturopathic medicines you are looking for is unavailable.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003ca href=\"https:\/\/shop.healthmasters.com.au\/products\/bioceuticals-clinical-saffropea\" target=\"_blank\" title=\"BioCeuticals Clinical SaffroPEA 10% off RRP | HealthMasters BioCeuticals Clinical\" rel=\"noopener\"\u003eBioCeuticals Clinical SaffroPEA\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca rel=\"noopener noreferrer\" title=\"Similar Products Containing Saffron | HealthMasters Saffron\" href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/saffron\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/collections\/all\/saffron\" target=\"_blank\"\u003eSimilar Products Containing Saffron\u003c\/a\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCan't see an appropriate naturopathic medicines, or have any other questions?\u003c\/p\u003e\n\u003cp\u003eYou can contact HealthMasters for assistance \u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003ca title=\"Contact HealthMasters For Assistance\" href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" data-mce-href=\"https:\/\/shop.healthmasters.com.au\/pages\/healthmasters-contact\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c!-- TABS --\u003e\n\u003ch5\u003eDose\u003c\/h5\u003e\n\u003ch2\u003eDose: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cstrong\u003eAdults:\u003c\/strong\u003e Take 1 tablet twice daily or as directed by your healthcare practitioner.\n\u003ch5\u003eFeatures \u0026amp; Benefits\u003c\/h5\u003e\n\u003ch2\u003eFeatures \u0026amp; Benefits: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCombination of saffron and St John’s wort, used in Persian traditional medicine and traditional western herbal medicine, respectively, to support a healthy mood balance, with mimosa, Siberian ginseng, zinc and myo-inositol.\u003c\/li\u003e\n\u003cli\u003eContains affron®, a clinically trialled saffron extract shown to support healthy mood balance. affron® is standardised to contain at least 3.5% Lepticrosalides®, a measure of phyto compounds including the bioactive compounds safranal and crocin.\u003c\/li\u003e\n\u003cli\u003eContains St John’s wort extract standardised to hypericin and \u0026lt;1% hyperforin.\u003c\/li\u003e\n\u003cli\u003eContains Siberian ginseng, used in traditional western herbal medicine as an adaptogen and to relieve fatigue, standardised to syringaresinol diglucosides.\u003c\/li\u003e\n\u003cli\u003eWith the addition of: an extract equivalent to 1.5g of mimosa; zinc, to support cognitive function; and myo-inositol, which supports the signal transduction between nerve cells.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e\n\u003ch5\u003eIngredient Summary\u003c\/h5\u003e\n\u003ch2\u003eIngredient Summary: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCrocus sativus (saffron)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSaffron has been used in Persian traditional medicine for supporting healthy mood balance1 and has emerged as a leading herb in healthy moods. affron® is a clinically trialled, non-GMO saffron extract standardised to \u0026gt;3.5% Lepticrosalides®, a measure of the bioactive compunds found in saffron, including safranal and crocin. In clinical trials, affron® administered at 28mg\/day was shown to improve healthy mood balance and decreased somatisation, and was reportedly well tolerated.2,3 Saffron exerts its actions through inhibition of the reuptake of the monoamines (dopamine, serotonin and noradrenaline), and enhanced binding and sensitisation of serotonin receptors.1,4-6\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHypericum perforatum (St John’s wort)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSt John’s wort has a long history of use in traditional western herbal medicine for symptoms of mild anxiety and to support a healthy mood balance. In vivo and in vitro clinical studies have conirmed numerous effects in the body including inhibited synaptic reuptake of monoamines (dopamine, serotonin and noradrenaline), enhanced binding and sensitisation of monoamine oxidase inhibition and gamma-aminobutyric acid (GABA) receptor binding.4,7\u003c\/p\u003e\n\u003cp\u003eThe St John’s wort extract used in NuroBalance Forte contains various lavonoids, including hypericin and less than 1% of hyperforin. Hyperforin is the constituent that is attributed to enzyme modulation and subsequent medicinal disruption.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEleutherococcus senticosus (Siberian ginseng)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSiberian ginseng has traditionally been used in western herbal medicine as an adaptogen, and to relieve fatigue.8 In an animal study, the ginsenosides found in Siberian ginseng upregulated brain-derived neurotrophic factor (BDNF) signalling pathways and acted on GABA receptors.9\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional support\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMimosa, zinc and myo-inositol complete the formulation of NuroBalance Forte.\u003c\/p\u003e\n\u003cp\u003eMimosa has a history of use in traditional Chinese medicine.10\u003c\/p\u003e\n\u003cp\u003eZinc is an essential trace mineral that supports nervous system function, and cognitive and mental function.7 The highest levels of zinc are found in the brain, with altered levels linked to changes in behaviour, mood, learning and mental function.11,12\u003c\/p\u003e\n\u003cp\u003eMyo-inositol is the bioactive form of inositol and is essential for signal transduction between nerve cells; it is a constituent of the intracellular phophatidyl inositol secondary messenger system, which is linked to several neurotransmitters including alpha-1-noradrenergic, serotonin, dopamine, norepinephrine, glutamate and cholinergic receptors.13\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch2\u003eIngredients: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003ctable width='100%\"'\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEach tablet contains:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHerbal extracts standardised equiv. to dry:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHypericum perforatum (St John's wort)\u003c\/td\u003e\n\u003ctd\u003e2.7g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 30px;\" data-mce-style=\"padding-left: 30px;\"\u003eequiv. to hyperforin\u003c\/td\u003e\n\u003ctd\u003e13.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 30px;\" data-mce-style=\"padding-left: 30px;\"\u003eequiv. to hypericins calc. as hypericin\u003c\/td\u003e\n\u003ctd\u003e1.49mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEleutherococcus senticosus (Siberian ginseng)\u003c\/td\u003e\n\u003ctd\u003e2g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 30px;\" data-mce-style=\"padding-left: 30px;\"\u003eequiv. to syringaresinol diglucosides\u003c\/td\u003e\n\u003ctd\u003e1.06mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHerbal extract equiv. to dry:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAlbizia julibrissin (mimosa) stem bark outer\u003c\/td\u003e\n\u003ctd\u003e1.5g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCrocus sativus (saffron) stigma (affron®)\u003c\/td\u003e\n\u003ctd\u003e42mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eNutrients:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZinc amino acid chelate\u003c\/td\u003e\n\u003ctd\u003e62.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-left: 30px;\" data-mce-style=\"padding-left: 30px;\"\u003eequiv. to zinc\u003c\/td\u003e\n\u003ctd\u003e12.5mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInositol (myo-inositol)\u003c\/td\u003e\n\u003ctd\u003e300mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch5\u003eFree Froms\u003c\/h5\u003e\n\u003ch2\u003eFree Froms: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eBioCeuticals Clinical NuroBalance Forte \u003c\/span\u003e\u003cspan\u003ehas No Added Dairy, No Added Gluten, No Added Shellfish, No Added Soy Protein, Vegan Friendly, Vegetarian Friendly, No Added Yeast.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003eWarnings\u003c\/h5\u003e\n\u003ch2\u003eWarnings: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cp\u003eSt John’s wort affects the way many prescription medicines work – including the oral contraceptive pill; consult your doctor.\u003c\/p\u003e\n\u003ch5\u003eCompanion Products:\u003c\/h5\u003e\n\u003ch2\u003eCompanion Products: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003ch2\u003eReferences: BioCeuticals Clinical NuroBalance Forte\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eBasti AA, Moshiri E, Noorbala AA, et al. Comparison of petal of Crocus sativus L. and luoxetine in the treatment of depressed outpatients: a pilot double-blind randomized trial. Prog Neuro-Psychopharmacol Biol Psychiatry 2007;31:439-442.\u003c\/li\u003e\n\u003cli\u003eKell G, Rao A, Beccaria G, et al. Affron®, a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial. Complement Ther Med 2017;33:58-64. 3. Lopresti AL, Drummond PD, Inarejos-García AM, et al. Affron®, a standardised extract from saffron (Crocus sativus L.) for the treatment of youth anxiety and depressive symptoms: a randomised, double-blind, placebo- scontrolled study. J Affect Disord 2018;232:349-357.\u003c\/li\u003e\n\u003cli\u003eSarris J, Panossian A, Schweitzer I, et al. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence. Eur Neuropsychopharm 2011;21(12):841-860.\u003c\/li\u003e\n\u003cli\u003eAkhondzadeh S, Tahmacebi-Pour N, Noorbala AA, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo- controlled trial. Phytother Res 2005;19(2):148-151.\u003c\/li\u003e\n\u003cli\u003eAkhondzadeh S, Fallah-Pour H, Afkham K, et al. Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double- blind randomized trial. BMC Complement Altern Med 2004;4(12).\u003c\/li\u003e\n\u003cli\u003eBraun L, Cohen M. Herbs and natural supplements: an evidence-based guide, 3rd ed. Sydney: Churchill Livingstone Elsevier, 2010.\u003c\/li\u003e\n\u003cli\u003eAmerican Botanical Council. Eleuthero root. Herbal medicine: expanded commission E, 1994. Viewed 30th July 2018, http:\/\/cms.herbalgram.org\/expandedE\/ Eleutheroroot.html?ts=1532925160\u0026amp;signature=dee3ecc afba172e 4930dcec9c4ef7f4c\u003c\/li\u003e\n\u003cli\u003eKim HJ, Kim P, Shin CY. A comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system. J Ginseng Res 2013;37(1):8-29.\u003c\/li\u003e\n\u003cli\u003eBensky D, Clavey S, Stoger E. Chinese herbal medicine materia medica, 3rd ed. Seattle: Eastland Press, 2004.\u003c\/li\u003e\n\u003cli\u003eNowak G, Szewczyk B, Pilc A. Zinc and depression. An update. Pharmacol Rep 2005;57(6):713-718.\u003c\/li\u003e\n\u003cli\u003eLai J, Moxey A, Nowak G, et al. The eficacy of zinc supplementation in depression: systematic review of randomised controlled trials. J Affect Disord 2012;136 (1 2):e31-39.\u003c\/li\u003e\n\u003cli\u003eInositol. Natural Medicines Database, 2018. Viewed 30th July 2018, https:\/\/naturalmedicines.therapeuticresearch com\/databases\/food,-herbs-supplements\/professional aspx?productid=299\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c!-- \/TABS --\u003e"}